Author results

1SOX
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SULFITE OXIDASE FROM CHICKEN LIVER
Descriptor:SULFITE OXIDASE, SULFATE ION, PHOSPHONIC ACIDMONO-(2-AMINO-5,6-DIMERCAPTO-4-OXO-3,7,8A,9,10,10A-HEXAHYDRO-4H-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-7-YLMETHYL)ESTER, ...
Authors:Kisker, C., Schindelin, H., Rees, D.C.
Deposit date:1997-12-31
Release date:1998-04-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Molecular basis of sulfite oxidase deficiency from the structure of sulfite oxidase.
Cell(Cambridge,Mass.), 91, 1997
1THJ
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CARBONIC ANHYDRASE FROM METHANOSARCINA
Descriptor:CARBONIC ANHYDRASE, ZINC ION
Authors:Kisker, C., Schindelin, H., Rees, D.C.
Deposit date:1996-04-02
Release date:1996-10-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A left-hand beta-helix revealed by the crystal structure of a carbonic anhydrase from the archaeon Methanosarcina thermophila.
EMBO J., 15, 1996
2TCT
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THE COMPLEX FORMED BETWEEN TET REPRESSOR AND TETRACYCLINE-MG2+ REVEALS MECHANISM OF ANTIBIOTIC RESISTANCE
Descriptor:TETRACYCLINE REPRESSOR, MAGNESIUM ION, 7-CHLOROTETRACYCLINE
Authors:Hinrichs, W., Kisker, C., Saenger, W.
Deposit date:1995-03-02
Release date:1996-04-03
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The complex formed between Tet repressor and tetracycline-Mg2+ reveals mechanism of antibiotic resistance.
J.Mol.Biol., 247, 1995
2XB5
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TET REPRESSOR (CLASS D) IN COMPLEX WITH 7-IODOTETRACYCLINE
Descriptor:TETRACYCLINE REPRESSOR PROTEIN CLASS D, 7-IODOTETRACYCLINE, MAGNESIUM ION, ...
Authors:Kisker, C., Saenger, W., Hinrichs, W.
Deposit date:2010-04-05
Release date:2010-10-06
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of the Tet Repressor-Tetracycline Complex and Regulation of Antibiotic Resistance.
Science, 264, 1994
1QQ0
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COBALT SUBSTITUTED CARBONIC ANHYDRASE FROM METHANOSARCINA THERMOPHILA
Descriptor:CARBONIC ANHYDRASE, COBALT (II) ION
Authors:Iverson, T.M., Alber, B.E., Kisker, C., Ferry, J.G., Rees, D.C.
Deposit date:1999-06-10
Release date:1999-06-24
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:A closer look at the active site of gamma-class carbonic anhydrases: high-resolution crystallographic studies of the carbonic anhydrase from Methanosarcina thermophila.
Biochemistry, 39, 2000
1QRE
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A CLOSER LOOK AT THE ACTIVE SITE OF GAMMA-CARBONIC ANHYDRASES: HIGH RESOLUTION CRYSTALLOGRAPHIC STUDIES OF THE CARBONIC ANHYDRASE FROM METHANOSARCINA THERMOPHILA
Descriptor:CARBONIC ANHYDRASE, BICARBONATE ION, COBALT (II) ION
Authors:Iverson, T.M., Alber, B.E., Kisker, C., Ferry, J.G., Rees, D.C.
Deposit date:1999-06-13
Release date:1999-06-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.46 Å)
Cite:A closer look at the active site of gamma-class carbonic anhydrases: high-resolution crystallographic studies of the carbonic anhydrase from Methanosarcina thermophila.
Biochemistry, 39, 2000
1QRF
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A CLOSER LOOK AT THE ACTIVE SITE OF GAMMA-CARBONIC ANHYDRASES: HIGH RESOLUTION CRYSTALLOGRAPHIC STUDIES OF THE CARBONIC ANHYDRASE FROM METHANOSARCINA THERMOPHILA
Descriptor:CARBONIC ANHYDRASE, SULFATE ION, COBALT (II) ION
Authors:Iverson, T.M., Alber, B.E., Kisker, C., Ferry, J.G., Rees, D.C.
Deposit date:1999-06-13
Release date:1999-06-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:A closer look at the active site of gamma-class carbonic anhydrases: high-resolution crystallographic studies of the carbonic anhydrase from Methanosarcina thermophila.
Biochemistry, 39, 2000
1QRG
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A CLOSER LOOK AND THE ACTIVE SITE OF GAMMA-CARBONIC ANHYDRASES: HIGH RESOLUTION CRYSTALLOGRAPHIC STUDIES OF THE CARBONIC ANHYDRASE FROM METHANOSARCINA THERMOPHILA
Descriptor:CARBONIC ANHYDRASE, ZINC ION
Authors:Iverson, T.M., Alber, B.E., Kisker, C., Ferry, J.G., Rees, D.C.
Deposit date:1999-06-13
Release date:1999-06-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:A closer look at the active site of gamma-class carbonic anhydrases: high-resolution crystallographic studies of the carbonic anhydrase from Methanosarcina thermophila.
Biochemistry, 39, 2000
1QRL
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A CLOSER LOOK AT THE ACTIVE SITE OF GAMMA-CARBONIC ANHYDRASES: HIGH RESOLUTION CRYSTALLOGRAPHIC STUDIES OF THE CARBONIC ANHYDRASE FROM METHANOSARCINA THERMOPHILA
Descriptor:CARBONIC ANHYDRASE, ZINC ION, BICARBONATE ION
Authors:Iverson, T.M., Alber, B.E., Kisker, C., Ferry, J.G., Rees, D.C.
Deposit date:1999-06-15
Release date:1999-06-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:A closer look at the active site of gamma-class carbonic anhydrases: high-resolution crystallographic studies of the carbonic anhydrase from Methanosarcina thermophila.
Biochemistry, 39, 2000
1QRM
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A CLOSER LOOK AT THE ACTIVE SITE OF GAMMA-CARBONIC ANHYDRASES: HIGH RESOLUTION CRYSTAL STRUCTURES OF THE CARBONIC ANHYDRASE FROM METHANOSARCINA THERMOPHILA
Descriptor:CARBONIC ANHYDRASE, ZINC ION, SULFATE ION
Authors:Iverson, T.M., Alber, B.E., Kisker, C., Ferry, J.G., Rees, D.C.
Deposit date:1999-06-15
Release date:1999-06-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:A closer look at the active site of gamma-class carbonic anhydrases: high-resolution crystallographic studies of the carbonic anhydrase from Methanosarcina thermophila.
Biochemistry, 39, 2000
4BKQ
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ENOYL-ACP REDUCTASE FROM YERSINIA PESTIS (WILDTYPE)WITH COFACTOR NADH
Descriptor:PUTATIVE REDUCTASE YPZ3_3519, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE
Authors:Hirschbeck, M.W., Neckles, C., Tonge, P.J., Kisker, C.
Deposit date:2013-04-29
Release date:2014-05-14
Last modified:2016-06-15
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Selectivity of Pyridone- and Diphenyl Ether-Based Inhibitors for the Yersinia Pestis Fabv Enoyl-Acp Reductase.
Biochemistry, 55, 2016
4BKR
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ENOYL-ACP REDUCTASE FROM YERSINIA PESTIS (WILDTYPE, REMOVED HISTAG) WITH COFACTOR NADH
Descriptor:PUTATIVE REDUCTASE YPZ3_3519, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, GLYCEROL, ...
Authors:Hirschbeck, M.W., Neckles, C., Tonge, P.J., Kisker, C.
Deposit date:2013-04-29
Release date:2014-05-14
Last modified:2016-06-15
Method:X-RAY DIFFRACTION (1.798 Å)
Cite:Selectivity of Pyridone- and Diphenyl Ether-Based Inhibitors for the Yersinia Pestis Fabv Enoyl-Acp Reductase.
Biochemistry, 55, 2016
5G2O
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YERSINIA PESTIS FABV VARIANT T276A
Descriptor:ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [NADH], 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, DIMETHYL SULFOXIDE
Authors:Pschibul, A., Kuper, J., HIrschbeck, M., Kisker, C.
Deposit date:2016-04-11
Release date:2016-05-25
Last modified:2016-06-15
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Selectivity of Pyridone- and Diphenyl Ether-Based Inhibitors for the Yersinia Pestis Fabv Enoyl-Acp Reductase.
Biochemistry, 55, 2016
1Q51
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CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS MENB IN COMPLEX WITH ACETOACETYL-COENZYME A, A KEY ENZYME IN VITAMIN K2 BIOSYNTHESIS
Descriptor:menB, ACETOACETYL-COENZYME A
Authors:Truglio, J.J., Theis, K., Feng, Y., Gajda, R., Machutta, C., Tonge, P.J., Kisker, C., TB Structural Genomics Consortium (TBSGC)
Deposit date:2003-08-05
Release date:2004-01-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of Mycobacterium tuberculosis MenB, a key enzyme in vitamin K2 biosynthesis.
J.Biol.Chem., 278, 2003
1Q52
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CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS MENB, A KEY ENZYME IN VITAMIN K2 BIOSYNTHESIS
Descriptor:menB
Authors:Truglio, J.J., Theis, K., Feng, Y., Gajda, R., Machutta, C., Tonge, P.J., Kisker, C., TB Structural Genomics Consortium (TBSGC)
Deposit date:2003-08-05
Release date:2004-01-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of Mycobacterium tuberculosis MenB, a key enzyme in vitamin K2 biosynthesis.
J.Biol.Chem., 278, 2003
2FHS
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STRUCTURE OF ACYL CARRIER PROTEIN BOUND TO FABI, THE ENOYL REDUCTASE FROM ESCHERICHIA COLI
Descriptor:enoyl-[acyl-carrier-protein] reductase, NADH-dependent, Acyl carrier protein
Authors:Kolappan, S., Novichenok, P., Rafi, S., Simmerling, C., Tonge, P.J., Kisker, C.
Deposit date:2005-12-27
Release date:2006-10-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of Acyl Carrier Protein Bound to FabI, the FASII Enoyl Reductase from Escherichia coli.
J.Biol.Chem., 281, 2006
4BKO
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ENOYL-ACP REDUCATASE FABV FROM BURKHOLDERIA PSEUDOMALLEI (APO)
Descriptor:PUTATIVE REDUCTASE BURPS305_1051, GLYCEROL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ...
Authors:Hirschbeck, M.W., Neckles, C., Tonge, P.J., Kisker, C.
Deposit date:2013-04-29
Release date:2014-05-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Point Mutation Changes Substrate Binding Mechanism and Inhibitor Specificity of Yersinia Pestis Enoyl- Acp Reductase Fabv
To be Published
4V98
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THE 8S SNRNP ASSEMBLY INTERMEDIATE
Descriptor:Small nuclear ribonucleoprotein Sm D1, Small nuclear ribonucleoprotein Sm D2, Small nuclear ribonucleoprotein E, ...
Authors:Grimm, C., Pelz, J.P., Schindelin, H., Diederichs, K., Kuper, J., Kisker, C.
Deposit date:2012-05-15
Release date:2014-07-09
Last modified:2014-12-10
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural Basis of Assembly Chaperone- Mediated snRNP Formation.
Mol.Cell, 49, 2013
5JAI
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YERSINIA PESTIS FABV VARIANT T276G
Descriptor:Enoyl-[acyl-carrier-protein] reductase [NADH], 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, DIMETHYL SULFOXIDE, ...
Authors:Pschibul, A., Kuper, J., HIrschbeck, M., Kisker, C.
Deposit date:2016-04-12
Release date:2016-05-25
Last modified:2016-06-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Selectivity of Pyridone- and Diphenyl Ether-Based Inhibitors for the Yersinia pestis FabV Enoyl-ACP Reductase.
Biochemistry, 55, 2016
5JAM
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YERSINIA PESTIS FABV VARIANT T276V
Descriptor:Enoyl-[acyl-carrier-protein] reductase [NADH], 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, DIMETHYL SULFOXIDE
Authors:Pschibul, A., Kuper, J., HIrschbeck, M., Kisker, C.
Deposit date:2016-04-12
Release date:2016-05-25
Last modified:2016-06-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Selectivity of Pyridone- and Diphenyl Ether-Based Inhibitors for the Yersinia pestis FabV Enoyl-ACP Reductase.
Biochemistry, 55, 2016
5JAQ
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YERSINIA PESTIS FABV VARIANT T276C
Descriptor:Enoyl-[acyl-carrier-protein] reductase [NADH], 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, DIMETHYL SULFOXIDE
Authors:Pschibul, A., Kuper, J., HIrschbeck, M., Kisker, C.
Deposit date:2016-04-12
Release date:2016-05-25
Last modified:2016-06-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Selectivity of Pyridone- and Diphenyl Ether-Based Inhibitors for the Yersinia pestis FabV Enoyl-ACP Reductase.
Biochemistry, 55, 2016
5LY9
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STRUCTURE OF MITAT 1.1
Descriptor:Variant surface glycoprotein MITAT 1.1, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Schaefer, C., Bartossek, T., Jones, N., Kuper, J., Kisker, C., Engstler, M.
Deposit date:2016-09-26
Release date:2017-09-20
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structural basis for the shielding function of the dynamic trypanosome variant surface glycoprotein coat.
Nat Microbiol, 2, 2017
6FDK
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STRUCTURE OF CHLAMYDIA TRACHOMATIS EFFECTOR PROTEIN CDU1 BOUND TO UBIQUITIN
Descriptor:Deubiquitinase and deneddylase Dub1, Polyubiquitin-B, CHLORIDE ION, ...
Authors:Ramirez, Y., Kisker, C.
Deposit date:2017-12-25
Release date:2018-08-15
Last modified:2018-10-17
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural Basis of Substrate Recognition and Covalent Inhibition of Cdu1 from Chlamydia trachomatis.
ChemMedChem, 13, 2018
6FDQ
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STRUCTURE OF CHLAMYDIA TRACHOMATIS EFFECTOR PROTEIN CDU1 BOUND TO COMPOUND 5
Descriptor:Deubiquitinase and deneddylase Dub1, N-benzyl-2-[(Z)-iminomethyl]pyrimidine-5-carboxamide
Authors:Ramirez, Y., Kisker, C., Altmann, E.
Deposit date:2017-12-26
Release date:2018-08-15
Last modified:2018-10-17
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Basis of Substrate Recognition and Covalent Inhibition of Cdu1 from Chlamydia trachomatis.
ChemMedChem, 13, 2018
6FDU
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STRUCTURE OF CHLAMYDIA TRACHOMATIS EFFECTOR PROTEIN CDU1 BOUND TO COMPOUND 3
Descriptor:Deubiquitinase and deneddylase Dub1, CHLORIDE ION, (2~{S},3~{S})-2-[[(2~{S})-2-[3,5-bis(chloranyl)phenyl]-2-(dimethylamino)ethanoyl]amino]-~{N}-[[2-(iminomethyl)pyrimidin-4-yl]methyl]-3-methyl-pentanamide
Authors:Ramirez, Y., Kisker, C., Altmann, E.
Deposit date:2017-12-26
Release date:2018-08-15
Last modified:2018-10-17
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Basis of Substrate Recognition and Covalent Inhibition of Cdu1 from Chlamydia trachomatis.
ChemMedChem, 13, 2018