Author results

1N5W
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CRYSTAL STRUCTURE OF THE CU,MO-CO DEHYDROGENASE (CODH); OXIDIZED FORM
Descriptor:Carbon monoxide dehydrogenase small chain, Carbon monoxide dehydrogenase large chain, Carbon monoxide dehydrogenase medium chain, ...
Authors:Dobbek, H., Gremer, L., Kiefersauer, R., Huber, R., Meyer, O.
Deposit date:2002-11-07
Release date:2002-12-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Catalysis at a dinuclear [CuSMo(=O)OH] cluster in a CO dehydrogenase resolved at 1.1-A resolution
Proc.Natl.Acad.Sci.USA, 99, 2002
1N60
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CRYSTAL STRUCTURE OF THE CU,MO-CO DEHYDROGENASE (CODH); CYANIDE-INACTIVATED FORM
Descriptor:Carbon monoxide dehydrogenase small chain, Carbon monoxide dehydrogenase large chain, Carbon monoxide dehydrogenase medium chain, ...
Authors:Dobbek, H., Gremer, L., Kiefersauer, R., Huber, R., Meyer, O.
Deposit date:2002-11-08
Release date:2002-12-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.19 Å)
Cite:Catalysis at a dinuclear [CuSMo(=O)OH] cluster in a CO dehydrogenase resolved at 1.1-A resolution
Proc.Natl.Acad.Sci.USA, 99, 2002
1N61
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CRYSTAL STRUCTURE OF THE CU,MO-CO DEHYDROGENASE (CODH); DITHIONITE REDUCED STATE
Descriptor:Carbon monoxide dehydrogenase small chain, Carbon monoxide dehydrogenase large chain, Carbon monoxide dehydrogenase medium chain, ...
Authors:Dobbek, H., Gremer, L., Kiefersauer, R., Huber, R., Meyer, O.
Deposit date:2002-11-08
Release date:2002-12-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Catalysis at a dinuclear [CuSMo(=O)OH] cluster in a CO dehydrogenase resolved at 1.1-A resolution
Proc.Natl.Acad.Sci.USA, 99, 2002
1N62
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CRYSTAL STRUCTURE OF THE MO,CU-CO DEHYDROGENASE (CODH), N-BUTYLISOCYANIDE-BOUND STATE
Descriptor:Carbon monoxide dehydrogenase small chain, Carbon monoxide dehydrogenase large chain, Carbon monoxide dehydrogenase medium chain, ...
Authors:Dobbek, H., Gremer, L., Kiefersauer, R., Huber, R., Meyer, O.
Deposit date:2002-11-08
Release date:2002-12-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.09 Å)
Cite:Catalysis at a dinuclear [CuSMo(=O)OH] cluster in a CO dehydrogenase resolved at 1.1-A resolution
Proc.Natl.Acad.Sci.USA, 99, 2002
1N63
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CRYSTAL STRUCTURE OF THE CU,MO-CO DEHYDROGENASE (CODH); CARBON MONOXIDE REDUCED STATE
Descriptor:Carbon monoxide dehydrogenase small chain, Carbon monoxide dehydrogenase large chain, Carbon monoxide dehydrogenase medium chain, ...
Authors:Dobbek, H., Gremer, L., Kiefersauer, R., Huber, R., Meyer, O.
Deposit date:2002-11-08
Release date:2002-12-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.21 Å)
Cite:Catalysis at a dinuclear [CuSMo(=O)OH] cluster in a CO dehydrogenase resolved at 1.1-A resolution
Proc.Natl.Acad.Sci.USA, 99, 2002
1ORV
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CRYSTAL STRUCTURE OF PORCINE DIPEPTIDYL PEPTIDASE IV (CD26)
Descriptor:dipeptidyl peptidase IV, N-ACETYL-D-GLUCOSAMINE, SULFATE ION, ...
Authors:Engel, M., Hoffmann, T., Wagner, L., Wermann, M., Heiser, U., Kiefersauer, R., Huber, R., Bode, W., Demuth, H.U., Brandstetter, H.
Deposit date:2003-03-16
Release date:2003-05-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The Crystal Structure of Dipeptidyl Peptidase IV (CD26) Reveals its Functional Regulation and Enzymatic Mechanism
Proc.Natl.Acad.Sci.USA, 100, 2003
1ORW
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CRYSTAL STRUCTURE OF PORCINE DIPEPTIDYL PEPTIDASE IV (CD26) IN COMPLEX WITH A PEPTIDOMIMETIC INHIBITOR
Descriptor:dipeptidyl peptidase IV, N-ACETYL-D-GLUCOSAMINE, SULFATE ION, ...
Authors:Engel, M., Hoffmann, T., Wagner, L., Wermann, M., Heiser, U., Kiefersauer, R., Huber, R., Bode, W., Demuth, H.U., Brandstetter, H.
Deposit date:2003-03-16
Release date:2003-05-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.84 Å)
Cite:The Crystal Structure of Dipeptidyl Peptidase IV (CD26) Reveals its Functional Regulation and Enzymatic Mechanism
Proc.Natl.Acad.Sci.USA, 100, 2003
1P8J
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CRYSTAL STRUCTURE OF THE PROPROTEIN CONVERTASE FURIN
Descriptor:Furin precursor, DECANOYL-ARG-VAL-LYS-ARG-CHLOROMETHYLKETONE INHIBITOR, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Henrich, S., Cameron, A., Bourenkov, G.P., Kiefersauer, R., Huber, R., Lindberg, I., Bode, W., Than, M.E.
Deposit date:2003-05-07
Release date:2003-07-08
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The Crystal Structure of the Proprotein Processing Proteinase Furin Explains its Stringent Specificity
Nat.Struct.Biol., 10, 2003
1SEZ
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CRYSTAL STRUCTURE OF PROTOPORPHYRINOGEN IX OXIDASE
Descriptor:Protoporphyrinogen oxidase, mitochondrial, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Koch, M., Breithaupt, C., Kiefersauer, R., Freigang, J., Huber, R., Messerschmidt, A.
Deposit date:2004-02-19
Release date:2004-04-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of protoporphyrinogen IX oxidase: a key enzyme in haem and chlorophyll biosynthesis.
Embo J., 23, 2004
1Z1W
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CRYSTAL STRUCTURES OF THE TRICORN INTERACTING FACOR F3 FROM THERMOPLASMA ACIDOPHILUM, A ZINC AMINOPEPTIDASE IN THREE DIFFERENT CONFORMATIONS
Descriptor:Tricorn protease interacting factor F3, ZINC ION, SULFATE ION
Authors:Kyrieleis, O.J.P., Goettig, P., Kiefersauer, R., Huber, R., Brandstetter, H.
Deposit date:2005-03-07
Release date:2005-05-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal Structures of the Tricorn Interacting Factor F3 from Thermoplasma acidophilum, a Zinc Aminopeptidase in Three Different Conformations
J.MOL.BIOL., 394, 2005
1Z5H
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CRYSTAL STRUCTURES OF THE TRICORN INTERACTING FACTOR F3 FROM THERMOPLASMA ACIDOPHILUM
Descriptor:Tricorn protease interacting factor F3, SULFATE ION, ZINC ION
Authors:Kyrieleis, O.J.P., Goettig, P., Kiefersauer, R., Huber, R., Brandstetter, H.
Deposit date:2005-03-18
Release date:2005-06-28
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structures of the Tricorn Interacting Factor F3 from Thermoplasma acidophilum, a Zinc Aminopeptidase in Three Different Conformations
J.MOL.BIOL., 349, 2005
3RO5
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CRYSTAL STRUCTURE OF INFLUENZA A VIRUS NUCLEOPROTEIN WITH LIGAND
Descriptor:Nucleocapsid protein, [4-(2-chloro-4-nitrophenyl)piperazin-1-yl][3-(2-methoxyphenyl)-5-methyl-1,2-oxazol-4-yl]methanone
Authors:Pearce, B.C., Edavettal, S., McDonnell, P.A., Lewis, H.A., Steinbacher, S., Baldwin, E.T., Langley, D.R., Maskos, K., Mortl, M., Kiefersauer, R.
Deposit date:2011-04-25
Release date:2011-09-14
Last modified:2011-09-28
Method:X-RAY DIFFRACTION (2.66 Å)
Cite:Inhibition of influenza virus replication via small molecules that induce the formation of higher-order nucleoprotein oligomers.
Proc.Natl.Acad.Sci.USA, 108, 2011
4DYA
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CRYSTAL STRUCTURE OF WSN/A INFLUENZA NUCLEOPROTEIN WITH BMS-885986 LIGAND BOUND
Descriptor:Nucleocapsid protein, N-[4-chloranyl-5-[4-[[3-(2-methoxyphenyl)-5-methyl-1,2-oxazol-4-yl]carbonyl]piperazin-1-yl]-2-nitro-phenyl]furan-2-carboxamide
Authors:Lewis, H.A., Baldwin, E.T., Steinbacher, S., Maskos, K., Mortl, M., Kiefersauer, R., Edavettal, S., McDonnell, P.A., Pearce, B.C., Langley, D.R.
Deposit date:2012-02-28
Release date:2013-03-06
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:To be determined
To be Published
4DYB
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CRYSTAL STRUCTURE OF WSN/A INFLUENZA NUCLEOPROTEIN WITH BMS-883559 LIGAND BOUND
Descriptor:Nucleocapsid protein, N-[4-chloranyl-5-[4-[[3-(2-methoxyphenyl)-5-methyl-1,2-oxazol-4-yl]carbonyl]piperazin-1-yl]-2-nitro-phenyl]thiophene-2-carboxamide
Authors:Lewis, H.A., Baldwin, E.T., Steinbacher, S., Maskos, K., Mortl, M., Kiefersauer, R., Edavettal, S., McDonnell, P.A., Pearce, B.C., Langley, D.R.
Deposit date:2012-02-28
Release date:2013-03-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:To be determined
To be Published
4DYN
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CRYSTAL STRUCTURE OF WSN/A INFLUENZA NUCLEOPROTEIN WITH BMS-885838 LIGAND BOUND
Descriptor:Nucleocapsid protein, N-[4-chloranyl-5-[4-[[3-(2-methoxyphenyl)-5-methyl-1,2-oxazol-4-yl]carbonyl]piperazin-1-yl]-2-nitro-phenyl]pyridine-2-carboxamide
Authors:Lewis, H.A., Baldwin, E.T., Steinbacher, S., Maskos, K., Mortl, M., Kiefersauer, R., Edavettal, S., McDonnell, P.A., Pearce, B.C., Langley, D.R.
Deposit date:2012-02-29
Release date:2013-03-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:To be determined
To be Published
4DYP
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CRYSTAL STRUCTURE OF WSN/A INFLUENZA NUCLEOPROTEIN WITH BMS-831780 LIGAND BOUND
Descriptor:Nucleocapsid protein, [4-(5-bromanyl-3-methyl-pyridin-2-yl)piperazin-1-yl]-[3-(2-chlorophenyl)-5-methyl-1,2-oxazol-4-yl]methanone
Authors:Lewis, H.A., Baldwin, E.T., Steinbacher, S., Maskos, K., Mortl, M., Kiefersauer, R., Edavettal, S., McDonnell, P.A., Pearce, B.C., Langley, D.R.
Deposit date:2012-02-29
Release date:2013-03-06
Method:X-RAY DIFFRACTION (2.82 Å)
Cite:To be determined
To be Published
4DYS
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CRYSTAL STRUCTURE OF APO SWINE FLU INFLUENZA NUCLEOPROTEIN
Descriptor:Nucleocapsid protein
Authors:Lewis, H.A., Baldwin, E.T., Steinbacher, S., Maskos, K., Mortl, M., Kiefersauer, R., Edavettal, S., McDonnell, P.A., Pearce, B.C., Langley, D.R.
Deposit date:2012-02-29
Release date:2013-03-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:To be determined
To be Published
4DYT
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CRYSTAL STRUCTURE OF WSN/A INFLUENZA NUCLEOPROTEIN WITH THREE MUTATIONS (E53D, Y289H, Y313V)
Descriptor:Nucleocapsid protein
Authors:Lewis, H.A., Baldwin, E.T., Steinbacher, S., Maskos, K., Mortl, M., Kiefersauer, R., Edavettal, S., McDonnell, P.A., Pearce, B.C., Langley, D.R.
Deposit date:2012-02-29
Release date:2013-03-06
Method:X-RAY DIFFRACTION (3 Å)
Cite:To be determined
To be Published
3TG6
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CRYSTAL STRUCTURE OF INFLUENZA A VIRUS NUCLEOPROTEIN WITH LIGAND
Descriptor:Nucleocapsid protein, [4-(2-chloro-4-nitrophenyl)piperazin-1-yl][3-(2-chloropyridin-3-yl)-5-methyl-1,2-oxazol-4-yl]methanone
Authors:Pearce, B.C., Lewis, H.A., McDonnell, P.A., Steinbacher, S., Kiefersauer, R., Mortl, M., Maskos, K., Edavettal, S., Baldwin, E.T., Langley, D.R.
Deposit date:2011-08-17
Release date:2012-08-29
Method:X-RAY DIFFRACTION (3 Å)
Cite:Biophysical and Structural Characterization of a Novel Class of Influenza Virus Inhibitors
To be Published
4LI5
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EGFR-K IN COMPLEX WITH N-[3-[[5-CHLORO-4-(1H-INDOL-3-YL)PYRIMIDIN-2-YL]AMINO]-4-METHOXY-PHENYL] PROP-2-ENAMIDE
Descriptor:Epidermal growth factor receptor, N-(3-{[5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino}-4-methoxyphenyl)propanamide, SODIUM ION
Authors:Debreczeni, J.E., Seiffert, G.B., Kiefersauer, R., Augustin, M., Nagel, S., Ward, R., Anderton, M., Ashton, S., Bethel, P., Box, M., Butterworth, S., Colclough, N., Chroley, C., Chuaqui, C., Cross, D., Eberlein, C., Finlay, R., Hill, G., Grist, M., Klinowska, T., Lane, C., Martin, S., Orme, J., Smith, P., Wang, F., Waring, M.
Deposit date:2013-07-02
Release date:2013-08-28
Last modified:2013-09-25
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:Structure- and Reactivity-Based Development of Covalent Inhibitors of the Activating and Gatekeeper Mutant Forms of the Epidermal Growth Factor Receptor (EGFR).
J.Med.Chem., 56, 2013
1FQ3
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CRYSTAL STRUCTURE OF HUMAN GRANZYME B
Descriptor:GRANZYME B, 2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Estebanez-Perpina, E., Fuentes-Prior, P., Belorgey, D., Rubin, H., Bode, W.
Deposit date:2000-09-03
Release date:2001-01-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal structure of the caspase activator human granzyme B, a proteinase highly specific for an Asp-P1 residue.
Biol.Chem., 381, 2000
5EOG
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STRUCTURE OF FULL-LENGTH HUMAN MAB21L1
Descriptor:Protein mab-21-like 1, CITRIC ACID
Authors:de Oliveira Mann, C.C., Witte, G., Hopfner, K.-P.
Deposit date:2015-11-10
Release date:2016-06-01
Last modified:2016-06-22
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Structural and biochemical characterization of the cell fate determining nucleotidyltransferase fold protein MAB21L1.
Sci Rep, 6, 2016
5EOM
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STRUCTURE OF FULL-LENGTH HUMAN MAB21L1 WITH BOUND CTP
Descriptor:Protein mab-21-like 1, CITRIC ACID, trimethylamine oxide, ...
Authors:de Oliveira Mann, C.C., Witte, G., Hopfner, K.-P.
Deposit date:2015-11-10
Release date:2016-06-01
Last modified:2016-06-22
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structural and biochemical characterization of the cell fate determining nucleotidyltransferase fold protein MAB21L1.
Sci Rep, 6, 2016
5NYW
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ANBU (ANCESTRAL BETA-SUBUNIT) FROM YERSINIA BERCOVIERI
Descriptor:Proteasome subunit, SULFATE ION, 1,2-ETHANEDIOL, ...
Authors:Piasecka, A., Czapinska, H., Vielberg, M., Szczepanowski, R.H., Reed, S., Groll, M., Bochtler, M.
Deposit date:2017-05-12
Release date:2017-05-24
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (2.501 Å)
Cite:The Y. bercovieri Anbu crystal structure sheds light on the evolution of highly (pseudo)symmetric multimers.
J. Mol. Biol., 430, 2018