Author results

1QRJ
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SOLUTION STRUCTURE OF HTLV-I CAPSID PROTEIN
Descriptor:HTLV-I CAPSID PROTEIN
Authors:Khorasanizadeh, S., Campos-Olivas, R., Clark, C.A., Summers, M.F.
Deposit date:1999-06-14
Release date:1999-07-13
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Sequence-specific 1H, 13C and 15N chemical shift assignment and secondary structure of the HTLV-I capsid protein.
J.Biomol.NMR, 14, 1999
5TFP
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CRYSTAL STRUCTURE OF THE SETDB2 AMINO TERMINAL DOMAIN
Descriptor:Histone-lysine N-methyltransferase SETDB2, GLYCEROL, L(+)-TARTARIC ACID
Authors:Khorasanizadeh, S., Kim, Y.
Deposit date:2016-09-26
Release date:2017-10-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Identification of a helical dimerization domain in SETDB2 lysine methyltransferase
To Be Published
1MT6
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STRUCTURE OF HISTONE H3 K4-SPECIFIC METHYLTRANSFERASE SET7/9 WITH ADOHCY
Descriptor:SET9, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Jacobs, S.A., Harp, J.M., Devarakonda, S., Kim, Y., Rastinejad, F., Khorasanizadeh, S.
Deposit date:2002-09-20
Release date:2002-11-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The active site of the SET domain is constructed on a knot
Nat.Struct.Biol., 9, 2002
1MUF
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STRUCTURE OF HISTONE H3 K4-SPECIFIC METHYLTRANSFERASE SET7/9
Descriptor:SET9
Authors:Jacobs, S.A., Harp, J.M., Devarakonda, S., Kim, Y., Rastinejad, F., Khorasanizadeh, S.
Deposit date:2002-09-23
Release date:2002-11-06
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:The active site of the SET domain is constructed on a knot
Nat.Struct.Biol., 9, 2002
1OSV
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STRUCTURAL BASIS FOR BILE ACID BINDING AND ACTIVATION OF THE NUCLEAR RECEPTOR FXR
Descriptor:Bile acid receptor, Nuclear receptor coactivator 2, 6-ETHYL-CHENODEOXYCHOLIC ACID
Authors:Mi, L.Z., Devarakonda, S., Harp, J.M., Han, Q., Pellicciari, R., Willson, T.M., Khorasanizadeh, S., Rastinejad, F.
Deposit date:2003-03-20
Release date:2004-03-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Basis for Bile Acid Binding and Activation of the Nuclear Receptor FXR
Mol.Cell, 11, 2003
1OT7
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STRUCTURAL BASIS FOR 3-DEOXY-CDCA BINDING AND ACTIVATION OF FXR
Descriptor:Bile Acid Receptor, dodecamer peptide fragment of RPGR-interacting protein 1, 6-ETHYL-CHENODEOXYCHOLIC ACID, ...
Authors:Mi, L.Z., Devarakonda, S., Harp, J.M., Han, Q., Pellicciari, R., Willson, T.M., Khorasanizadeh, S., Rastinejad, F.
Deposit date:2003-03-21
Release date:2004-03-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural Basis for Bile Acid Binding and Activation of the Nuclear Receptor FXR
Mol.Cell, 11, 2003
6E3S
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CRYSTAL STRUCTURE OF THE HETERODIMERIC HIF-2 COMPLEX WITH ANTAGONIST PT2385
Descriptor:Aryl hydrocarbon receptor nuclear translocator, Endothelial PAS domain-containing protein 1, 3-{[(1S)-2,2-difluoro-1-hydroxy-7-(methylsulfonyl)-2,3-dihydro-1H-inden-4-yl]oxy}-5-fluorobenzonitrile
Authors:Wu, D., Su, X., Lu, J., Li, S., Hood, B., Vasile, S., Potluri, N., Diao, X., Kim, Y., Khorasanizadeh, S., Rastinejad, F.
Deposit date:2018-07-15
Release date:2019-02-13
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (3 Å)
Cite:Bidirectional modulation of HIF-2 activity through chemical ligands.
Nat. Chem. Biol., 15, 2019
6E3T
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CRYSTAL STRUCTURE OF THE HETERODIMERIC HIF-2 COMPLEX WITH ANTAGONIST T1001
Descriptor:Aryl hydrocarbon receptor nuclear translocator, Endothelial PAS domain-containing protein 1, (6S)-6-(4-bromophenyl)-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole
Authors:Wu, D., Su, X., Lu, J., Li, S., Hood, B., Vasile, S., Potluri, N., Diao, X., Kim, Y., Khorasanizadeh, S., Rastinejad, F.
Deposit date:2018-07-15
Release date:2019-02-13
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (3 Å)
Cite:Bidirectional modulation of HIF-2 activity through chemical ligands.
Nat. Chem. Biol., 15, 2019
6E3U
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CRYSTAL STRUCTURE OF THE HETERODIMERIC HIF-2 COMPLEX WITH AGONIST M1001
Descriptor:Aryl hydrocarbon receptor nuclear translocator, Endothelial PAS domain-containing protein 1, 3-{[2-(pyrrolidin-1-yl)phenyl]amino}-1H-1lambda~6~,2-benzothiazole-1,1-dione
Authors:Wu, D., Su, X., Lu, J., Li, S., Hood, B., Vasile, S., Potluri, N., Diao, X., Kim, Y., Khorasanizadeh, S., Rastinejad, F.
Deposit date:2018-07-15
Release date:2019-02-13
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Bidirectional modulation of HIF-2 activity through chemical ligands.
Nat. Chem. Biol., 15, 2019
1A6Y
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REVERBA ORPHAN NUCLEAR RECEPTOR/DNA COMPLEX
Descriptor:DNA (5'-D(*CP*AP*AP*CP*TP*AP*GP*GP*TP*CP*AP*CP*(5IT)P*AP*GP*GP*TP*CP*AP*G)-3'), DNA (5'-D(*CP*TP*GP*AP*CP*CP*TP*AP*GP*TP*GP*AP*CP*CP*TP*AP*GP*TP*TP*G)-3'), ORPHAN NUCLEAR RECEPTOR NR1D1, ...
Authors:Zhao, Q., Khorasanizadeh, S., Rastinejad, F.
Deposit date:1998-03-04
Release date:1998-10-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural elements of an orphan nuclear receptor-DNA complex.
Mol.Cell, 1, 1998
1DSZ
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STRUCTURE OF THE RXR/RAR DNA-BINDING DOMAIN HETERODIMER IN COMPLEX WITH THE RETINOIC ACID RESPONSE ELEMENT DR1
Descriptor:DNA (5'-D(*CP*AP*GP*GP*TP*CP*AP*AP*AP*GP*GP*TP*CP*AP*G)-3'), DNA (5'-D(*CP*TP*GP*AP*CP*CP*TP*TP*TP*GP*AP*CP*CP*TP*G)-3'), RETINOIC ACID RECEPTOR ALPHA, ...
Authors:Rastinejad, F., Wagner, T., Zhao, Q., Khorasanizadeh, S.
Deposit date:2000-01-10
Release date:2000-07-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure of the RXR-RAR DNA-binding complex on the retinoic acid response element DR1.
EMBO J., 19, 2000
1KNA
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CHROMO DOMAIN OF HP1 COMPLEXED WITH HISTONE H3 TAIL CONTAINING DIMETHYLLYSINE 9.
Descriptor:HETEROCHROMATIN PROTEIN 1, METHYLATED Histone H3
Authors:Jacobs, S.A., Khorasanizadeh, S.
Deposit date:2001-12-18
Release date:2002-03-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of HP1 chromodomain bound to a lysine 9-methylated histone H3 tail.
Science, 295, 2002
1KNE
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CHROMO DOMAIN OF HP1 COMPLEXED WITH HISTONE H3 TAIL CONTAINING TRIMETHYLLYSINE 9
Descriptor:HETEROCHROMATIN PROTEIN 1, Trimethylated Histone H3
Authors:Jacobs, S.A., Khorasanizadeh, S.
Deposit date:2001-12-18
Release date:2002-03-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of HP1 chromodomain bound to a lysine 9-methylated histone H3 tail.
Science, 295, 2002
1PDQ
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POLYCOMB CHROMODOMAIN COMPLEXED WITH THE HISTONE H3 TAIL CONTAINING TRIMETHYLLYSINE 27.
Descriptor:Polycomb protein, Histone H3.3
Authors:Fischle, W., Wang, Y., Jacobs, S.A., Kim, Y., Allis, C.D., Khorasanizadeh, S.
Deposit date:2003-05-20
Release date:2003-08-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Molecular basis for the discrimination of repressive methyl-lysine marks in histone H3 by Polycomb and HP1 chromodomains
Genes Dev., 17, 2003
1Q3L
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CHROMODOMAIN OF HP1 COMPLEXED WITH HISTONE H3 TAIL CONTAINING MONOMETHYLLYSINE 9.
Descriptor:Heterochromatin protein 1, Histone H3
Authors:Jacobs, S.A., Khorasanizadeh, S.
Deposit date:2003-07-30
Release date:2004-10-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Chromodomain Of HP1 Complexed With Histone H3 Tail Containing monomethyllysine 9
To be Published
2B2T
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TANDEM CHROMODOMAINS OF HUMAN CHD1 COMPLEXED WITH HISTONE H3 TAIL CONTAINING TRIMETHYLLYSINE 4 AND PHOSPHOTHREONINE 3
Descriptor:Chromodomain-helicase-DNA-binding protein 1, Histone H3 tail
Authors:Flanagan IV, J.F., Mi, L.-Z., Chruszcz, M., Cymborowski, M., Clines, K.L., Kim, Y., Minor, W., Rastinejad, F., Khorasanizadeh, S.
Deposit date:2005-09-19
Release date:2005-12-27
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Double chromodomains cooperate to recognize the methylated histone H3 tail.
Nature, 438, 2005
2B2U
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TANDEM CHROMODOMAINS OF HUMAN CHD1 COMPLEXED WITH HISTONE H3 TAIL CONTAINING TRIMETHYLLYSINE 4 AND DIMETHYLARGININE 2
Descriptor:Chromodomain-helicase-DNA-binding protein 1, Histone H3
Authors:Flanagan IV, J.F., Mi, L.-Z., Chruszcz, M., Cymborowski, M., Clines, K.L., Kim, Y., Minor, W., Rastinejad, F., Khorasanizadeh, S.
Deposit date:2005-09-19
Release date:2005-12-27
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Double chromodomains cooperate to recognize the methylated histone H3 tail.
Nature, 438, 2005
2B2V
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CRYSTAL STRUCTURE ANALYSIS OF HUMAN CHD1 CHROMODOMAINS 1 AND 2 BOUND TO HISTONE H3 RESI 1-15 MEK4
Descriptor:Chromodomain-helicase-DNA-binding protein 1, Histone H3
Authors:Flanagan IV, J.F., Mi, L.-Z., Chruszcz, M., Cymborowski, M., Clines, K.L., Kim, Y., Minor, W., Rastinejad, F., Khorasanizadeh, S.
Deposit date:2005-09-19
Release date:2005-12-27
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Double chromodomains cooperate to recognize the methylated histone H3 tail.
Nature, 438, 2005
2B2W
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TANDEM CHROMODOMAINS OF HUMAN CHD1 COMPLEXED WITH HISTONE H3 TAIL CONTAINING TRIMETHYLLYSINE 4
Descriptor:Chromodomain-helicase-DNA-binding protein 1, Histone H3
Authors:Flanagan IV, J.F., Mi, L.-Z., Chruszcz, M., Cymborowski, M., Clines, K.L., Kim, Y., Minor, W., Rastinejad, F., Khorasanizadeh, S.
Deposit date:2005-09-19
Release date:2005-12-27
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Double chromodomains cooperate to recognize the methylated histone H3 tail.
Nature, 438, 2005
2B2Y
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TANDEM CHROMODOMAINS OF HUMAN CHD1
Descriptor:Chromodomain-helicase-DNA-binding protein 1
Authors:Flanagan IV, J.F., Mi, L.-Z., Chruszcz, M., Cymborowski, M., Clines, K.L., Kim, Y., Minor, W., Rastinejad, F., Khorasanizadeh, S.
Deposit date:2005-09-19
Release date:2005-12-27
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Double chromodomains cooperate to recognize the methylated histone H3 tail.
Nature, 438, 2005
2H1E
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TANDEM CHROMODOMAINS OF BUDDING YEAST CHD1
Descriptor:Chromo domain protein 1
Authors:Flanagan IV, J.F., Khorasanizadeh, S.
Deposit date:2006-05-16
Release date:2007-03-27
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Molecular Implications of Evolutionary Differences in CHD Double Chromodomains.
J.Mol.Biol., 369, 2007
2M2L
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SOLUTION STRUCTURE OF ENTAMOEBA HISTOLYTICA HP1 CHROMODOMAIN
Descriptor:Putative uncharacterized protein
Authors:Wiggins, K.R., Ren, X., Ali, I.K.M., Petri, W.A., Khorasanizadeh, S.
Deposit date:2012-12-28
Release date:2014-05-14
Method:SOLUTION NMR
Cite:Characterization of putative readers of epigenetic methyl-marks from Entamoeba histolytica
To be Published
3M9Q
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DROSOPHILA MSL3 CHROMODOMAIN
Descriptor:Protein male-specific lethal-3
Authors:Kim, D., Huang, P., Rastinejad, F., Khorasanizadeh, S.
Deposit date:2010-03-22
Release date:2010-07-21
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.29 Å)
Cite:Corecognition of DNA and a methylated histone tail by the MSL3 chromodomain.
Nat.Struct.Mol.Biol., 17, 2010
3OA6
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HUMAN MSL3 CHROMODOMAIN BOUND TO DNA AND H4K20ME1 PEPTIDE
Descriptor:Male-specific lethal 3 homolog, DNA (5'-D(*GP*CP*TP*AP*GP*GP*TP*CP*AP*AP*AP*GP*GP*TP*CP*A)-3'), DNA (5'-D(*CP*TP*GP*AP*CP*CP*TP*TP*TP*GP*AP*CP*CP*TP*AP*G)-3'), ...
Authors:Kim, D., Huang, P., Rastinejad, F., Khorasanizadeh, S.
Deposit date:2010-08-04
Release date:2010-08-18
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Corecognition of DNA and a methylated histone tail by the MSL3 chromodomain.
Nat.Struct.Mol.Biol., 17, 2010
3P7J
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DROSOPHILA HP1A CHROMO SHADOW DOMAIN
Descriptor:Heterochromatin protein 1, GLYCEROL
Authors:Kim, D., Chruszcz, M., Minor, W., Khorasanizadeh, S.
Deposit date:2010-10-12
Release date:2011-02-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The HP1a Disordered C Terminus and Chromo Shadow Domain Cooperate to Select Target Peptide Partners.
Chembiochem, 12, 2011
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