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3U5Z
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BU of 3u5z by Molmil
Structure of T4 Bacteriophage clamp loader bound to the T4 clamp, primer-template DNA, and ATP analog
Descriptor: ADENOSINE-5'-DIPHOSPHATE, DNA polymerase accessory protein 44, DNA polymerase accessory protein 62, ...
Authors:Kelch, B.A, Makino, D.L, O'Donnell, M, Kuriyan, J.
Deposit date:2011-10-11
Release date:2012-01-04
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:How a DNA polymerase clamp loader opens a sliding clamp.
Science, 334, 2011
3U60
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BU of 3u60 by Molmil
Structure of T4 Bacteriophage Clamp Loader Bound To Open Clamp, DNA and ATP Analog
Descriptor: ADENOSINE-5'-DIPHOSPHATE, DNA polymerase accessory protein 44, DNA polymerase accessory protein 62, ...
Authors:Kelch, B.A, Makino, D.L, O'Donnell, M, Kuriyan, J.
Deposit date:2011-10-11
Release date:2012-01-04
Method:X-RAY DIFFRACTION (3.34 Å)
Cite:How a DNA polymerase clamp loader opens a sliding clamp.
Science, 334, 2011
3U61
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BU of 3u61 by Molmil
Structure of T4 Bacteriophage Clamp Loader Bound To Closed Clamp, DNA and ATP Analog and ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, DNA polymerase accessory protein 44, DNA polymerase accessory protein 62, ...
Authors:Kelch, B.A, Makino, D.L, O'Donnell, M, Kuriyan, J.
Deposit date:2011-10-11
Release date:2012-01-04
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:How a DNA polymerase clamp loader opens a sliding clamp.
Science, 334, 2011
3URE
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BU of 3ure by Molmil
Repack mutant (T181I, W199L, Q210I) of alpha-Lytic Protease
Descriptor: Alpha-lytic protease, SULFATE ION
Authors:Kelch, B.A, Agard, D.A.
Deposit date:2011-11-22
Release date:2012-05-23
Last modified:2012-07-18
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:Functional modulation of a protein folding landscape via side-chain distortion.
Proc.Natl.Acad.Sci.USA, 109, 2012
3URC
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BU of 3urc by Molmil
T181G mutant of alpha-Lytic Protease
Descriptor: Alpha-lytic protease, GLYCEROL, SULFATE ION
Authors:Kelch, B.A, Agard, D.A.
Deposit date:2011-11-22
Release date:2012-05-23
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Functional modulation of a protein folding landscape via side-chain distortion.
Proc.Natl.Acad.Sci.USA, 109, 2012
3URD
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BU of 3urd by Molmil
T181A mutant of alpha-Lytic Protease
Descriptor: Alpha-lytic protease, GLYCEROL, SULFATE ION
Authors:Kelch, B.A, Agard, D.A.
Deposit date:2011-11-22
Release date:2012-05-23
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (1.08 Å)
Cite:Functional modulation of a protein folding landscape via side-chain distortion.
Proc.Natl.Acad.Sci.USA, 109, 2012
2OUA
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BU of 2oua by Molmil
Crystal Structure of Nocardiopsis Protease (NAPase)
Descriptor: 1,4-DIETHYLENE DIOXIDE, 4-(2-AMINOETHYL)BENZENESULFONYL FLUORIDE, GLYCEROL, ...
Authors:Kelch, B.A, Agard, D.A.
Deposit date:2007-02-09
Release date:2007-02-20
Last modified:2012-06-06
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural and mechanistic exploration of Acid resistance: kinetic stability facilitates evolution of extremophilic behavior
J.Mol.Biol., 368, 2007
2PFE
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BU of 2pfe by Molmil
Crystal Structure of Thermobifida fusca Protease A (TFPA)
Descriptor: 4-(2-AMINOETHYL)BENZENESULFONYL FLUORIDE, Alkaline serine protease, GLYCEROL, ...
Authors:Kelch, B.A, Agard, D.A.
Deposit date:2007-04-04
Release date:2007-07-03
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (1.436 Å)
Cite:Mesophile versus Thermophile: Insights Into the Structural Mechanisms of Kinetic Stability
J.Mol.Biol., 370, 2007
6D0Q
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BU of 6d0q by Molmil
Structure of a DNA retention-prone PCNA variant
Descriptor: Proliferating cell nuclear antigen
Authors:Kelch, B.A, Gaubitz, C.
Deposit date:2018-04-10
Release date:2019-05-15
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.80051017 Å)
Cite:Effective mismatch repair depends on timely control of PCNA retention on DNA by the Elg1 complex.
Nucleic Acids Res., 47, 2019
6D0R
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BU of 6d0r by Molmil
Structure of a DNA retention-prone PCNA variant
Descriptor: Proliferating cell nuclear antigen
Authors:Kelch, B.A, Gaubitz, C.
Deposit date:2018-04-10
Release date:2019-05-15
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.85856962 Å)
Cite:Effective mismatch repair depends on timely control of PCNA retention on DNA by the Elg1 complex.
Nucleic Acids Res., 47, 2019
8VAL
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BU of 8val by Molmil
Structure of the E. coli clamp loader bound to the beta clamp in a Open-DNAp/t conformation
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Beta sliding clamp, ...
Authors:Landeck, J.T, Kelch, B.A.
Deposit date:2023-12-11
Release date:2024-03-27
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Differences between bacteria and eukaryotes in clamp loader mechanism, a conserved process underlying DNA replication.
J.Biol.Chem., 2024
8VAM
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BU of 8vam by Molmil
Structure of the E. coli clamp loader bound to the beta clamp in a Semi-Open conformation
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Beta sliding clamp, ...
Authors:Landeck, J.T, Kelch, B.A.
Deposit date:2023-12-11
Release date:2024-03-27
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Differences between bacteria and eukaryotes in clamp loader mechanism, a conserved process underlying DNA replication.
J.Biol.Chem., 2024
8VAN
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BU of 8van by Molmil
Structure of the E. coli clamp loader bound to the beta clamp in an Initial-Binding conformation
Descriptor: Beta sliding clamp, DNA polymerase III subunit delta, DNA polymerase III subunit delta', ...
Authors:Landeck, J.T, Pajak, J, Kelch, B.A.
Deposit date:2023-12-11
Release date:2024-03-27
Method:ELECTRON MICROSCOPY (7.7 Å)
Cite:Differences between bacteria and eukaryotes in clamp loader mechanism, a conserved process underlying DNA replication.
J.Biol.Chem., 2024
8VAP
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BU of 8vap by Molmil
Structure of the E. coli clamp loader bound to the beta clamp in a Fully-Open conformation
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Beta sliding clamp, ...
Authors:Landeck, J.T, Kelch, B.A.
Deposit date:2023-12-11
Release date:2024-03-27
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Differences between bacteria and eukaryotes in clamp loader mechanism, a conserved process underlying DNA replication.
J.Biol.Chem., 2024
8VAQ
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BU of 8vaq by Molmil
Structure of the E. coli clamp loader bound to the beta clamp in a Closed-DNA1 conformation
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Beta sliding clamp, ...
Authors:Landeck, J.T, Kelch, B.A.
Deposit date:2023-12-11
Release date:2024-03-27
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Differences between bacteria and eukaryotes in clamp loader mechanism, a conserved process underlying DNA replication.
J.Biol.Chem., 2024
8VAR
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BU of 8var by Molmil
Structure of the E. coli clamp loader bound to the beta clamp in a Closed-DNA2 conformation
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Beta sliding clamp, ...
Authors:Landeck, J.T, Kelch, B.A.
Deposit date:2023-12-11
Release date:2024-03-27
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Differences between bacteria and eukaryotes in clamp loader mechanism, a conserved process underlying DNA replication.
J.Biol.Chem., 2024
8VAS
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BU of 8vas by Molmil
Structure of the E. coli clamp loader bound to the beta clamp in an Altered-Collar conformation
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Beta sliding clamp, ...
Authors:Landeck, J.T, Kelch, B.A.
Deposit date:2023-12-11
Release date:2024-03-27
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Differences between bacteria and eukaryotes in clamp loader mechanism, a conserved process underlying DNA replication.
J.Biol.Chem., 2024
8VAT
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BU of 8vat by Molmil
Structure of the E. coli clamp loader bound to the beta clamp in a Open-RNAp/t conformation
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Beta sliding clamp, ...
Authors:Landeck, J.T, Kelch, B.A.
Deposit date:2023-12-11
Release date:2024-03-27
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Differences between bacteria and eukaryotes in clamp loader mechanism, a conserved process underlying DNA replication.
J.Biol.Chem., 2024
8E84
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BU of 8e84 by Molmil
Human PCNA mutant- C148S
Descriptor: Proliferating cell nuclear antigen
Authors:Magrino, J, Page, B, Gaubitz, C, Kelch, B.A.
Deposit date:2022-08-25
Release date:2023-04-12
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:A thermosensitive PCNA allele underlies an ataxia-telangiectasia-like disorder.
J.Biol.Chem., 299, 2023
6O3H
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BU of 6o3h by Molmil
Icosahedral reconstruction of the thermophilic bacteriophage P74-26 capsid
Descriptor: Major head protein, P74-26 Head Decoration Protein
Authors:Stone, N.P, Demo, G, Agnello, E, Kelch, B.A.
Deposit date:2019-02-26
Release date:2019-07-24
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Principles for enhancing virus capsid capacity and stability from a thermophilic virus capsid structure.
Nat Commun, 10, 2019
5TGE
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BU of 5tge by Molmil
Thermus Phage P74-26 Large Terminase Nuclease Domain
Descriptor: Phage terminase large subunit
Authors:Hilbert, B.J, Hayes, J.A, Stone, N.P, Kelch, B.A.
Deposit date:2016-09-27
Release date:2017-01-25
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The large terminase DNA packaging motor grips DNA with its ATPase domain for cleavage by the flexible nuclease domain.
Nucleic Acids Res., 45, 2017
6BL5
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BU of 6bl5 by Molmil
Head decoration protein from the hyperthermophilic phage P74-26
Descriptor: Head decoration protein
Authors:Stone, N.P, Hilbert, B.J, Hidalgo, D, Halloran, K.T, Kelch, B.A.
Deposit date:2017-11-09
Release date:2018-02-21
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:A Hyperthermophilic Phage Decoration Protein Suggests Common Evolutionary Origin with Herpesvirus Triplex Proteins and an Anti-CRISPR Protein.
Structure, 26, 2018
6V1I
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BU of 6v1i by Molmil
Cryo-EM reconstruction of the thermophilic bacteriophage P74-26 small terminase- symmetric
Descriptor: Small terminase protein
Authors:Hayes, J.A, Hilbert, B.J, Gaubitz, C, Stone, N.P, Kelch, B.A.
Deposit date:2019-11-20
Release date:2020-02-12
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:A thermophilic phage uses a small terminase protein with a fixed helix-turn-helix geometry.
J.Biol.Chem., 295, 2020
7U1P
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BU of 7u1p by Molmil
RFC:PCNA bound to DNA with a ssDNA gap of five nucleotides
Descriptor: ADENOSINE-5'-DIPHOSPHATE, DNA - Primer, DNA - Template, ...
Authors:Liu, X, Gaubitz, C, Pajak, J, Kelch, B.A.
Deposit date:2022-02-21
Release date:2022-07-06
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (3 Å)
Cite:A second DNA binding site on RFC facilitates clamp loading at gapped or nicked DNA.
Elife, 11, 2022
7U19
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BU of 7u19 by Molmil
RFC:PCNA bound to nicked DNA
Descriptor: ADENOSINE-5'-DIPHOSPHATE, DNA, MAGNESIUM ION, ...
Authors:Liu, X, Gaubitz, C, Pajak, J, Kelch, B.A.
Deposit date:2022-02-20
Release date:2022-07-06
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:A second DNA binding site on RFC facilitates clamp loading at gapped or nicked DNA.
Elife, 11, 2022

 

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