Author results

2Q7E
  • Download 2q7e
  • View 2q7e
Molmil generated image of 2q7e
THE STRUCTURE OF PYRROLYSYL-TRNA SYNTHETASE BOUND TO AN ATP ANALOGUE
Descriptor:Pyrrolysyl-tRNA synthetase, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Kavran, J.M., Steitz, T.A.
Deposit date:2007-06-06
Release date:2007-07-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of pyrrolysyl-tRNA synthetase, an archaeal enzyme for genetic code innovation.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2Q7G
  • Download 2q7g
  • View 2q7g
Molmil generated image of 2q7g
PYRROLYSINE TRNA SYNTHETASE BOUND TO A PYRROLYSINE ANALOGUE (CYC) AND ATP
Descriptor:Pyrrolysyl-tRNA synthetase, MAGNESIUM ION, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Kavran, J.M., Steitz, T.A.
Deposit date:2007-06-06
Release date:2007-07-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of pyrrolysyl-tRNA synthetase, an archaeal enzyme for genetic code innovation.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2Q7H
  • Download 2q7h
  • View 2q7h
Molmil generated image of 2q7h
PYRROLYSYL-TRNA SYNTHETASE BOUND TO ADENYLATED PYRROLYSINE AND PYROPHOSPHATE
Descriptor:Pyrrolysyl-tRNA synthetase, 1,2-ETHANEDIOL, (2R)-2-AMINO-6-({[(2S,3R)-3-METHYLPYRROLIDIN-2-YL]CARBONYL}AMINO)HEXANOYL [(2S,3R,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL HYDROGEN (R)-PHOSPHATE, ...
Authors:Kavran, J.M., Steitz, T.A.
Deposit date:2007-06-06
Release date:2007-07-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of pyrrolysyl-tRNA synthetase, an archaeal enzyme for genetic code innovation.
Proc.Natl.Acad.Sci.Usa, 104, 2007
3N1F
  • Download 3n1f
  • View 3n1f
Molmil generated image of 3n1f
CRYSTAL STRUCTURE OF IHHN BOUND TO CDOFN3
Descriptor:Indian hedgehog protein, Cell adhesion molecule-related/down-regulated by oncogenes, ZINC ION, ...
Authors:Kavran, J.M., Leahy, D.J.
Deposit date:2010-05-15
Release date:2010-06-02
Last modified:2013-06-19
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:All mammalian Hedgehog proteins interact with cell adhesion molecule, down-regulated by oncogenes (CDO) and brother of CDO (BOC) in a conserved manner.
J.Biol.Chem., 285, 2010
3N1G
  • Download 3n1g
  • View 3n1g
Molmil generated image of 3n1g
CRYSTAL STRUCTURE OF DHHN BOUND TO BOCFN3
Descriptor:Desert hedgehog protein, Brother of CDO, CALCIUM ION, ...
Authors:Kavran, J.M., Leahy, D.J.
Deposit date:2010-05-15
Release date:2010-06-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:All mammalian hedgehog proteins interact with CDO and BOC in a conserved manner.
J.Biol.Chem., 2010
3N1M
  • Download 3n1m
  • View 3n1m
Molmil generated image of 3n1m
CRYSTAL STRUCTURE OF IHHN BOUND TO BOCFN3
Descriptor:Indian hedgehog protein, Brother of CDO, ZINC ION, ...
Authors:Kavran, J.M., Leahy, D.J.
Deposit date:2010-05-15
Release date:2010-06-02
Last modified:2013-06-19
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:All mammalian Hedgehog proteins interact with cell adhesion molecule, down-regulated by oncogenes (CDO) and brother of CDO (BOC) in a conserved manner.
J.Biol.Chem., 285, 2010
3N1O
  • Download 3n1o
  • View 3n1o
Molmil generated image of 3n1o
CRYSTAL STRUCTURE OF IHHN
Descriptor:Indian hedgehog protein, ZINC ION, CALCIUM ION
Authors:Kavran, J.M., Leahy, D.J.
Deposit date:2010-05-16
Release date:2010-06-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:All mammalian hedgehog proteins interact with CDO and BOC in a conserved manner.
J.Biol.Chem., 2010
3N1P
  • Download 3n1p
  • View 3n1p
Molmil generated image of 3n1p
CRYSTAL STRUCTURE OF IHHN BOUND TO BOCFN3
Descriptor:Indian hedgehog protein, Brother of CDO, ZINC ION, ...
Authors:Kavran, J.M., Leahy, D.J.
Deposit date:2010-05-16
Release date:2010-06-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:All mammalian hedgehog proteins interact with CDO and BOC in a conserved manner.
J.Biol.Chem., 2010
3N1Q
  • Download 3n1q
  • View 3n1q
Molmil generated image of 3n1q
CRYSTAL STRUCTURE OF DHHN BOUND TO CDOFN3
Descriptor:Desert hedgehog protein, Cell adhesion molecule-related/down-regulated by oncogenes, ZINC ION, ...
Authors:Kavran, J.M., Leahy, D.J.
Deposit date:2010-05-16
Release date:2010-06-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.89 Å)
Cite:All mammalian hedgehog proteins interact with CDO and BOC in a conserved manner.
J.Biol.Chem., 2010
3N1R
  • Download 3n1r
  • View 3n1r
Molmil generated image of 3n1r
CRYSTAL STRUCTURE OF SHHN
Descriptor:Sonic hedgehog protein, ZINC ION, CALCIUM ION
Authors:Kavran, J.M., Leahy, D.J.
Deposit date:2010-05-16
Release date:2010-06-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:Crystal Structure of ShhN
TO BE PUBLISHED
2QA4
  • Download 2qa4
  • View 2qa4
Molmil generated image of 2qa4
A MORE COMPLETE STRUCTURE OF THE THE L7/L12 STALK OF THE HALOARCULA MARISMORTUI 50S LARGE RIBOSOMAL SUBUNIT
Descriptor:23S RIBOSOMAL RNA, 5S RIBOSOMAL RNA, 50S ribosomal protein L2P, ...
Authors:Steitz, T.A., Kavran, J.M.
Deposit date:2007-06-14
Release date:2008-04-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of the base of the L7/L12 stalk of the Haloarcula marismortui large ribosomal subunit: Analysis of L11 movements
J.Mol.Biol., 371, 2007
2ZIM
  • Download 2zim
  • View 2zim
Molmil generated image of 2zim
PYRROLYSYL-TRNA SYNTHETASE BOUND TO ADENYLATED PYRROLYSINE AND PYROPHOSPHATE
Descriptor:Pyrrolysyl-tRNA synthetase, 1,2-ETHANEDIOL, (2R)-2-AMINO-6-({[(2S,3R)-3-METHYLPYRROLIDIN-2-YL]CARBONYL}AMINO)HEXANOYL [(2S,3R,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL HYDROGEN (R)-PHOSPHATE, ...
Authors:Steitz, T.A., Kavran, J.M.
Deposit date:2008-02-19
Release date:2008-03-04
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of pyrrolysyl-tRNA synthetase, an archaeal enzyme for genetic code innovation.
Proc.Natl.Acad.Sci.Usa, 104, 2007
4PFJ
  • Download 4pfj
  • View 4pfj
Molmil generated image of 4pfj
THE STRUCTURE OF BI-ACETYLATED SAHH
Descriptor:Adenosylhomocysteinase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ADENOSINE
Authors:Kavran, J.M., Wang, Y., Cole, P.A., Leahy, D.J.
Deposit date:2014-04-29
Release date:2014-10-01
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Regulation of s-adenosylhomocysteine hydrolase by lysine acetylation.
J.Biol.Chem., 289, 2014
4PGF
  • Download 4pgf
  • View 4pgf
Molmil generated image of 4pgf
THE STRUCTURE OF MONO-ACETYLATED SAHH
Descriptor:Adenosylhomocysteinase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ADENOSINE
Authors:Kavran, J.M., Wang, Y., Cole, P.A., Leahy, D.J.
Deposit date:2014-05-01
Release date:2014-10-01
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Regulation of s-adenosylhomocysteine hydrolase by lysine acetylation.
J.Biol.Chem., 289, 2014
1FAO
  • Download 1fao
  • View 1fao
Molmil generated image of 1fao
STRUCTURE OF THE PLECKSTRIN HOMOLOGY DOMAIN FROM DAPP1/PHISH IN COMPLEX WITH INOSITOL 1,3,4,5-TETRAKISPHOSPHATE
Descriptor:DUAL ADAPTOR OF PHOSPHOTYROSINE AND 3-PHOSPHOINOSITIDES, INOSITOL-(1,3,4,5)-TETRAKISPHOSPHATE
Authors:Ferguson, K.M., Kavran, J.M., Sankaran, V.G., Fournier, E., Isakoff, S.J., Skolnik, E.Y., Lemmon, M.A.
Deposit date:2000-07-13
Release date:2000-07-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis for discrimination of 3-phosphoinositides by pleckstrin homology domains.
Mol.Cell, 6, 2000
1FB8
  • Download 1fb8
  • View 1fb8
Molmil generated image of 1fb8
STRUCTURE OF THE PLECKSTRIN HOMOLOGY DOMAIN FROM DAPP1/PHISH
Descriptor:DUAL ADAPTOR OF PHOSPHOTYROSINE AND 3-PHOSPHOINOSITIDES, PHOSPHATE ION
Authors:Ferguson, K.M., Kavran, J.M., Sankaran, V.G., Fournier, E., Isakoff, S.J., Skolnik, E.Y., Lemmon, M.A.
Deposit date:2000-07-14
Release date:2000-07-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis for discrimination of 3-phosphoinositides by pleckstrin homology domains.
Mol.Cell, 6, 2000
1FHW
  • Download 1fhw
  • View 1fhw
Molmil generated image of 1fhw
STRUCTURE OF THE PLECKSTRIN HOMOLOGY DOMAIN FROM GRP1 IN COMPLEX WITH INOSITOL(1,3,4,5,6)PENTAKISPHOSPHATE
Descriptor:GUANINE NUCLEOTIDE EXCHANGE FACTOR AND INTEGRIN BINDING PROTEIN HOMOLOG GRP1, INOSITOL-(1,3,4,5,6)-PENTAKISPHOSPHATE, SULFATE ION
Authors:Ferguson, K.M., Kavran, J.M., Sankaran, V.G., Fournier, E., Isakoff, S.J., Skolnik, E.Y., Lemmon, M.A.
Deposit date:2000-08-02
Release date:2000-08-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for discrimination of 3-phosphoinositides by pleckstrin homology domains
Mol.Cell, 6, 2000
1FHX
  • Download 1fhx
  • View 1fhx
Molmil generated image of 1fhx
STRUCTURE OF THE PLECKSTRIN HOMOLOGY DOMAIN FROM GRP1 IN COMPLEX WITH INOSITOL 1,3,4,5-TETRAKISPHOSPHATE
Descriptor:GUANINE NUCLEOTIDE EXCHANGE FACTOR AND INTEGRIN BINDING PROTEIN HOMOLOG GRP1, INOSITOL-(1,3,4,5)-TETRAKISPHOSPHATE, SULFATE ION
Authors:Ferguson, K.M., Kavran, J.M., Sankaran, V.G., Fournier, E., Isakoff, S.J., Skolnik, E.Y., Lemmon, M.A.
Deposit date:2000-08-02
Release date:2000-08-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for discrimination of 3-phosphoinositides by pleckstrin homology domains
Mol.Cell, 6, 2000
4Y6C
  • Download 4y6c
  • View 4y6c
Molmil generated image of 4y6c
Q17M CRYSTAL STRUCTURE OF PODOSOPORA ANSERINA PUTATIVE KINESIN LIGHT CHAIN NEARLY IDENTICAL TPR-LIKE REPEATS
Descriptor:ANSERINA PUTATIVE KINESIN LIGHT chain, SULFATE ION
Authors:Marold, J.D., Kavran, J.M., Bowman, G.D., Barrick, D.
Deposit date:2015-02-12
Release date:2015-10-07
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.772 Å)
Cite:A Naturally Occurring Repeat Protein with High Internal Sequence Identity Defines a New Class of TPR-like Proteins.
Structure, 23, 2015
4Y6W
  • Download 4y6w
  • View 4y6w
Molmil generated image of 4y6w
CRYSTAL STRUCTURE OF PODOSOPORA ANSERINA PUTATIVE KINESIN LIGHT CHAIN NEARLY IDENTICAL TPR-LIKE REPEATS
Descriptor:NaB(AB)3ACb - light chain TPR-like repeats
Authors:Marold, J.D., Kavran, J.M., Bowman, G.D., Barrick, D.
Deposit date:2015-02-13
Release date:2015-10-07
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (1.587 Å)
Cite:A Naturally Occurring Repeat Protein with High Internal Sequence Identity Defines a New Class of TPR-like Proteins.
Structure, 23, 2015
5KO7
  • Download 5ko7
  • View 5ko7
Molmil generated image of 5ko7
CRYSTAL STRUCTURE OF HALISCOMENOBACTER HYDROSSIS IODOTYROSINE DEIODINASE (IYD) BOUND TO FMN
Descriptor:Nitroreductase, FLAVIN MONONUCLEOTIDE
Authors:Ingavat, N., Kavran, J.M., Sun, Z., Rokita, S.
Deposit date:2016-06-29
Release date:2017-02-15
Last modified:2017-03-08
Method:X-RAY DIFFRACTION (2.248 Å)
Cite:Active Site Binding Is Not Sufficient for Reductive Deiodination by Iodotyrosine Deiodinase.
Biochemistry, 56, 2017
5KO8
  • Download 5ko8
  • View 5ko8
Molmil generated image of 5ko8
CRYSTAL STRUCTURE OF HALISCOMENOBACTER HYDROSSIS IODOTYROSINE DEIODINASE (IYD) BOUND TO FMN AND MONO-IODOTYROSINE (I-TYR)
Descriptor:Nitroreductase, FLAVIN MONONUCLEOTIDE, 3-IODO-TYROSINE
Authors:Ingavat, N., Kavran, J.M., Sun, Z., Rokita, S.E.
Deposit date:2016-06-29
Release date:2017-02-15
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Active Site Binding Is Not Sufficient for Reductive Deiodination by Iodotyrosine Deiodinase.
Biochemistry, 56, 2017
5KRD
  • Download 5krd
  • View 5krd
Molmil generated image of 5krd
CRYSTAL STRUCTURE OF HALISCOMENOBACTER HYDROSSIS IODOTYROSINE DEIODINASE (IYD) BOUND TO FMN AND 2-IODOPHENOL (2IP)
Descriptor:Nitroreductase, FLAVIN MONONUCLEOTIDE, 2-iodanylphenol
Authors:Ingavat, N., Kavran, J.M., Sun, Z., Rokita, S.
Deposit date:2016-07-07
Release date:2017-02-15
Last modified:2017-03-08
Method:X-RAY DIFFRACTION (2.103 Å)
Cite:Active Site Binding Is Not Sufficient for Reductive Deiodination by Iodotyrosine Deiodinase.
Biochemistry, 56, 2017
6BN1
  • Download 6bn1
  • View 6bn1
Molmil generated image of 6bn1
SALVADOR HIPPO SARAH DOMAIN COMPLEX
Descriptor:Serine/threonine-protein kinase hippo, Scaffold protein salvador, (4S)-2-METHYL-2,4-PENTANEDIOL, ...
Authors:Cairns, L., Kavran, J.M.
Deposit date:2017-11-15
Release date:2018-03-14
Last modified:2018-04-25
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Salvador has an extended SARAH domain that mediates binding to Hippo kinase.
J. Biol. Chem., 293, 2018
4Q6G
  • Download 4q6g
  • View 4q6g
Molmil generated image of 4q6g
CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN OF ACKRS-1 BOUND WITH N-ACETYL-LYSINE AND ADPNP
Descriptor:Pyrrolysine--tRNA ligase, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, 1,2-ETHANEDIOL, ...
Authors:Eiler, D.R., Kavran, J., Steitz, T.A.
Deposit date:2014-04-22
Release date:2014-11-12
Last modified:2014-12-10
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Polyspecific pyrrolysyl-tRNA synthetases from directed evolution.
Proc.Natl.Acad.Sci.USA, 111, 2014
<12>