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1ARJ
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BU of 1arj by Molmil
ARG-BOUND TAR RNA, NMR
Descriptor: ARGININE, TAR RNA
Authors:Aboul-Ela, F, Varani, G, Karn, J.
Deposit date:1995-08-30
Release date:1996-11-08
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:The structure of the human immunodeficiency virus type-1 TAR RNA reveals principles of RNA recognition by Tat protein.
J.Mol.Biol., 253, 1995
1ANR
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BU of 1anr by Molmil
CIS-ACTING RNA REGULATORY ELEMENT (HIV-1 TAR), NMR, 20 STRUCTURES
Descriptor: RNA REGULATORY ELEMENT TAR
Authors:Aboul-Ela, F, Varani, G, Karn, J.
Deposit date:1996-07-06
Release date:1997-01-11
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:Structure of HIV-1 TAR RNA in the absence of ligands reveals a novel conformation of the trinucleotide bulge.
Nucleic Acids Res., 24, 1996
1UUD
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BU of 1uud by Molmil
NMR structure of a synthetic small molecule, rbt203, bound to HIV-1 TAR RNA
Descriptor: N-[2-(2-{[(4-{[AMINO(IMINO)METHYL]AMINO}BUTYL)AMINO]METHYL}-4-METHOXYPHENOXY)ETHYL]GUANIDINE, RNA (5'-(*GP*GP*CP*AP*GP*AP*UP*CP*UP*GP*AP*GP *CP*CP*UP*GP*GP*GP*AP*GP*CP*UP*CP*UP*CP*UP*GP*CP*C) -3')
Authors:Davis, B, Afshar, M, Varani, G, Karn, J, Murchie, A.I.H, Lentzen, G, Drysdale, M.J, Potter, A.J, Bower, J, Aboul-Ela, F.
Deposit date:2003-12-18
Release date:2004-03-15
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Rational Design of Inhibitors of HIV-1 Tar RNA Through the Stabilisation of Electrostatic "Hot Spots"
J.Mol.Biol., 336, 2004
1UUI
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BU of 1uui by Molmil
NMR structure of a synthetic small molecule, rbt158, bound to HIV-1 TAR RNA
Descriptor: 4-[AMINO(IMINO)METHYL]-1-[2-(3-AMMONIOPROPOXY)-5-METHOXYBENZYL]PIPERAZIN-1-IUM, 5'-R(*GP*GP*CP*AP*GP*AP*UP*CP*UP*GP*AP*GP*CP* CP*UP*GP*GP*GP*AP*GP*CP*UP*CP*UP*CP*UP*GP*CP*C)-3'
Authors:Davis, B, Afshar, M, Varani, G, Karn, J, Murchie, A.I.H, Lentzen, G, Drysdale, M.J, Potter, A.J, Bower, J, Aboul-Ela, F.
Deposit date:2003-12-19
Release date:2004-02-12
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Rational Design of Inhibitors of HIV-1 Tar RNA Through the Stabilisation of Electrostatic "Hot Spots"
J.Mol.Biol., 336, 2004
1UTS
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BU of 1uts by Molmil
Designed HIV-1 TAR Binding Ligand
Descriptor: N-[2-(3-AMINOPROPOXY)-5-(1H-INDOL-5-YL)BENZYL]-N-(2-PIPERAZIN-1-YLETHYL)AMINE, RNA (5'-(*GP*GP*CP*AP*GP*AP*UP*CP*UP*GP*AP*GP *CP*CP*UP*GP*GP*GP*AP*GP*CP*UP*CP*UP*CP*UP*GP*CP*C) -3')
Authors:Davis, B, Murchie, A.I.H, Aboul-Ela, F, Karn, J.
Deposit date:2003-12-10
Release date:2004-02-12
Last modified:2021-05-05
Method:SOLUTION NMR
Cite:Structure-based drug design targeting an inactive RNA conformation: exploiting the flexibility of HIV-1 TAR RNA.
J.Mol.Biol., 336, 2004
6D2U
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BU of 6d2u by Molmil
Solution structure of a ultra-high affinity macrocycle bound to HIV-1 TAR RNA
Descriptor: DAB-VAL-ARG-THR-ARG-LYS-GLY-ARG-ARG-ILE-NOR-ILE-DPR-PRO, RNA (29-MER)
Authors:Shortridge, M.D, Varani, G.
Deposit date:2018-04-13
Release date:2018-12-12
Last modified:2023-11-15
Method:SOLUTION NMR
Cite:An ultra-high affinity ligand of HIV-1 TAR reveals the RNA structure recognized by P-TEFb.
Nucleic Acids Res., 47, 2019
2KDQ
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BU of 2kdq by Molmil
Simultaneous recognition of HIV-1 TAR RNA bulge and loop sequences by cyclic peptide mimic of Tat protein
Descriptor: HIV-1 TAR RNA, L-22 CYCLIC PEPTIDE
Authors:Davidson, A, Leeper, T.C, Varani, G.
Deposit date:2009-01-14
Release date:2009-06-23
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Simultaneous recognition of HIV-1 TAR RNA bulge and loop sequences by cyclic peptide mimics of Tat protein
Proc.Natl.Acad.Sci.USA, 106, 2009
1AKX
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BU of 1akx by Molmil
HIV-2 TRANS ACTIVATING REGION RNA COMPLEX WITH ARGININAMIDE, NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor: ARGININE, TAR RNA
Authors:Brodsky, A.S, Williamson, J.R.
Deposit date:1997-05-27
Release date:1997-11-19
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:Solution structure of the HIV-2 TAR-argininamide complex.
J.Mol.Biol., 267, 1997
1AJU
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BU of 1aju by Molmil
HIV-2 TAR-ARGININAMIDE COMPLEX, NMR, 20 STRUCTURES
Descriptor: ARGININE, TAR RNA
Authors:Brodsky, A.S, Williamson, J.R.
Deposit date:1997-05-10
Release date:1997-12-17
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:Solution structure of the HIV-2 TAR-argininamide complex.
J.Mol.Biol., 267, 1997

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