1ARJ
| ARG-BOUND TAR RNA, NMR | Descriptor: | ARGININE, TAR RNA | Authors: | Aboul-Ela, F, Varani, G, Karn, J. | Deposit date: | 1995-08-30 | Release date: | 1996-11-08 | Last modified: | 2022-02-16 | Method: | SOLUTION NMR | Cite: | The structure of the human immunodeficiency virus type-1 TAR RNA reveals principles of RNA recognition by Tat protein. J.Mol.Biol., 253, 1995
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1ANR
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1UUD
| NMR structure of a synthetic small molecule, rbt203, bound to HIV-1 TAR RNA | Descriptor: | N-[2-(2-{[(4-{[AMINO(IMINO)METHYL]AMINO}BUTYL)AMINO]METHYL}-4-METHOXYPHENOXY)ETHYL]GUANIDINE, RNA (5'-(*GP*GP*CP*AP*GP*AP*UP*CP*UP*GP*AP*GP *CP*CP*UP*GP*GP*GP*AP*GP*CP*UP*CP*UP*CP*UP*GP*CP*C) -3') | Authors: | Davis, B, Afshar, M, Varani, G, Karn, J, Murchie, A.I.H, Lentzen, G, Drysdale, M.J, Potter, A.J, Bower, J, Aboul-Ela, F. | Deposit date: | 2003-12-18 | Release date: | 2004-03-15 | Last modified: | 2011-07-13 | Method: | SOLUTION NMR | Cite: | Rational Design of Inhibitors of HIV-1 Tar RNA Through the Stabilisation of Electrostatic "Hot Spots" J.Mol.Biol., 336, 2004
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1UUI
| NMR structure of a synthetic small molecule, rbt158, bound to HIV-1 TAR RNA | Descriptor: | 4-[AMINO(IMINO)METHYL]-1-[2-(3-AMMONIOPROPOXY)-5-METHOXYBENZYL]PIPERAZIN-1-IUM, 5'-R(*GP*GP*CP*AP*GP*AP*UP*CP*UP*GP*AP*GP*CP* CP*UP*GP*GP*GP*AP*GP*CP*UP*CP*UP*CP*UP*GP*CP*C)-3' | Authors: | Davis, B, Afshar, M, Varani, G, Karn, J, Murchie, A.I.H, Lentzen, G, Drysdale, M.J, Potter, A.J, Bower, J, Aboul-Ela, F. | Deposit date: | 2003-12-19 | Release date: | 2004-02-12 | Last modified: | 2011-07-13 | Method: | SOLUTION NMR | Cite: | Rational Design of Inhibitors of HIV-1 Tar RNA Through the Stabilisation of Electrostatic "Hot Spots" J.Mol.Biol., 336, 2004
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1UTS
| Designed HIV-1 TAR Binding Ligand | Descriptor: | N-[2-(3-AMINOPROPOXY)-5-(1H-INDOL-5-YL)BENZYL]-N-(2-PIPERAZIN-1-YLETHYL)AMINE, RNA (5'-(*GP*GP*CP*AP*GP*AP*UP*CP*UP*GP*AP*GP *CP*CP*UP*GP*GP*GP*AP*GP*CP*UP*CP*UP*CP*UP*GP*CP*C) -3') | Authors: | Davis, B, Murchie, A.I.H, Aboul-Ela, F, Karn, J. | Deposit date: | 2003-12-10 | Release date: | 2004-02-12 | Last modified: | 2021-05-05 | Method: | SOLUTION NMR | Cite: | Structure-based drug design targeting an inactive RNA conformation: exploiting the flexibility of HIV-1 TAR RNA. J.Mol.Biol., 336, 2004
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6D2U
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2KDQ
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1AKX
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1AJU
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