Author results

4H1L
  • Download 4h1l
  • View 4h1l
Molmil generated image of 4h1l
TCR INTERACTION WITH PEPTIDE MIMICS OF NICKEL OFFERS STRUCTURAL INSIGHTS IN NICKEL CONTACT ALLERGY
Descriptor:HLA class II histocompatibility antigen, DR alpha chain, MHC class II antigen, ...
Authors:Kappler, J.W., Yin, L., Dai, S., Marrack, P.
Deposit date:2012-09-10
Release date:2012-11-14
Last modified:2013-09-04
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:T-cell receptor (TCR) interaction with peptides that mimic nickel offers insight into nickel contact allergy.
Proc.Natl.Acad.Sci.USA, 109, 2012
4H25
  • Download 4h25
  • View 4h25
Molmil generated image of 4h25
TCR INTERACTION WITH PEPTIDE MIMICS OF NICKEL OFFERS STRUCTURE INSIGHTS TO NICKEL CONTACT ALLERGY
Descriptor:HLA class II histocompatibility antigen, DR alpha chain, MHC class II antigen, ...
Authors:Kappler, J.W., Yin, L., Dai, S., Marrack, P., Crawford, F.
Deposit date:2012-09-12
Release date:2013-10-16
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:T-cell receptor (TCR) interaction with peptides that mimic nickel offers insight into nickel contact allergy.
Proc.Natl.Acad.Sci.USA, 109, 2012
4H26
  • Download 4h26
  • View 4h26
Molmil generated image of 4h26
TCR INTERACTION WITH PEPTIDE MIMICS OF NICKEL OFFERS STRUCTURE INSIGHT TO NICKEL CONTACT ALLERGY
Descriptor:HLA class II histocompatibility antigen, DR alpha chain, MHC class II antigen, ...
Authors:Kappler, J.W., Yin, L., Dai, S., Marrack, P., Crawford, F.
Deposit date:2012-09-12
Release date:2013-10-16
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:T-cell receptor (TCR) interaction with peptides that mimic nickel offers insight into nickel contact allergy.
Proc.Natl.Acad.Sci.USA, 109, 2012
1PQ0
  • Download 1pq0
  • View 1pq0
Molmil generated image of 1pq0
CRYSTAL STRUCTURE OF MOUSE BCL-XL
Descriptor:Apoptosis regulator Bcl-X
Authors:Liu, X., Dai, S., Zhu, Y., Marrack, P., Kappler, J.W.
Deposit date:2003-06-17
Release date:2003-09-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The structure of a Bcl-xl/Bim fragment complex: Implications for Bim function
Immunity, 19, 2003
1PQ1
  • Download 1pq1
  • View 1pq1
Molmil generated image of 1pq1
CRYSTAL STRUCTURE OF BCL-XL/BIM
Descriptor:Apoptosis regulator Bcl-X, BCL2-like protein 11
Authors:Liu, X., Dai, S., Zhu, Y., Marrack, P., Kappler, J.W.
Deposit date:2003-06-17
Release date:2003-09-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:The structure of a Bcl-xl/Bim fragment complex: Implications for Bim function
Immunity, 19, 2003
2G5B
  • Download 2g5b
  • View 2g5b
Molmil generated image of 2g5b
CRYSTAL STRUCTURE OF THE ANTI-BAX MONOCLONAL ANTIBODY 6A7 AND A BAX PEPTIDE.
Descriptor:6A7 Fab Light Chain, 6A7 Fab Heavy Chain, Bax Peptide, ...
Authors:Peyerl, F.W., Dai, S., Murphy, G.A., Marrack, P., Kappler, J.W.
Deposit date:2006-02-22
Release date:2006-07-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Elucidation of some Bax conformational changes through crystallization of an antibody-peptide complex.
Cell Death Differ., 14, 2007
3C5J
  • Download 3c5j
  • View 3c5j
Molmil generated image of 3c5j
CRYSTAL STRUCTURE OF HLA DR52C
Descriptor:HLA class II histocompatibility antigen, DR alpha chain, MHC class II antigen, ...
Authors:Dai, S., Kappler, J.W.
Deposit date:2008-01-31
Release date:2008-08-05
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The structure of HLA-DR52c: comparison to other HLA-DRB3 alleles.
Proc.Natl.Acad.Sci.USA, 105, 2008
3KPL
  • Download 3kpl
  • View 3kpl
Molmil generated image of 3kpl
CRYSTAL STRUCTURE OF HLA B*4402 IN COMPLEX WITH EEYLQAFTY A SELF PEPTIDE FROM THE ABCD3 PROTEIN
Descriptor:HLA class I histocompatibility antigen, B-44 alpha chain, Beta-2-microglobulin, ...
Authors:Macdonald, W.A., Chen, Z., Gras, S., Archbold, J.K., Tynan, F.E., Clements, C.S., Bharadwaj, M., Kjer-Nielsen, L., Saunders, P.M., Wilce, M.C., Crawford, F., Stadinsky, B., Jackson, D., Brooks, A.G., Purcell, A.W., Kappler, J.W., Burrows, S.R., Rossjohn, J., McCluskey, J.
Deposit date:2009-11-16
Release date:2009-12-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:T cell allorecognition via molecular mimicry.
Immunity, 31, 2009
3KPM
  • Download 3kpm
  • View 3kpm
Molmil generated image of 3kpm
CRYSTAL STRUCTURE OF HLA B*4402 IN COMPLEX WITH EEYLKAWTF, A MIMOTOPE
Descriptor:HLA class I histocompatibility antigen, B-44 alpha chain, Beta-2-microglobulin, ...
Authors:Macdonald, W.A., Chen, Z., Gras, S., Archbold, J.K., Tynan, F.E., Clements, C.S., Bharadwaj, M., Kjer-Nielsen, L., Saunders, P.M., Wilce, M.C., Crawford, F., Stadinsky, B., Jackson, D., Brooks, A.G., Purcell, A.W., Kappler, J.W., Burrows, S.R., Rossjohn, J., McCluskey, J.
Deposit date:2009-11-16
Release date:2009-12-22
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:T cell allorecognition via molecular mimicry.
Immunity, 31, 2009
3KPN
  • Download 3kpn
  • View 3kpn
Molmil generated image of 3kpn
CRYSTAL STRUCTURE OF HLA B*4403 IN COMPLEX WITH EEYLQAFTY A SELF PEPTIDE FROM THE ABCD3 PROTEIN
Descriptor:MHC class I antigen, Beta-2-microglobulin, EEYLQAFTY, ...
Authors:Macdonald, W.A., Chen, Z., Gras, S., Archbold, J.K., Tynan, F.E., Clements, C.S., Bharadwaj, M., Kjer-Nielsen, L., Saunders, P.M., Wilce, M.C., Crawford, F., Stadinsky, B., Jackson, D., Brooks, A.G., Purcell, A.W., Kappler, J.W., Burrows, S.R., Rossjohn, J., McCluskey, J.
Deposit date:2009-11-16
Release date:2009-12-22
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:T cell allorecognition via molecular mimicry.
Immunity, 31, 2009
3KPO
  • Download 3kpo
  • View 3kpo
Molmil generated image of 3kpo
CRYSTAL STRUCTURE OF HLA B*4403 IN COMPLEX WITH EEYLKAWTF, A MIMOTOPE
Descriptor:MHC class I antigen, Beta-2-microglobulin, EEYLKAWTF, ...
Authors:Macdonald, W.A., Chen, Z., Gras, S., Archbold, J.K., Tynan, F.E., Clements, C.S., Bharadwaj, M., Kjer-Nielsen, L., Saunders, P.M., Wilce, M.C., Crawford, F., Stadinsky, B., Jackson, D., Brooks, A.G., Purcell, A.W., Kappler, J.W., Burrows, S.R., Rossjohn, J., McCluskey, J.
Deposit date:2009-11-16
Release date:2009-12-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:T cell allorecognition via molecular mimicry.
Immunity, 31, 2009
3KPP
  • Download 3kpp
  • View 3kpp
Molmil generated image of 3kpp
CRYSTAL STRUCTURE OF HLA B*4405 IN COMPLEX WITH EEYLQAFTY A SELF PEPTIDE FROM THE ABCD3 PROTEIN
Descriptor:HLA class I histocompatibility antigen, B-44 alpha chain, Beta-2-microglobulin, ...
Authors:Macdonald, W.A., Chen, Z., Gras, S., Archbold, J.K., Tynan, F.E., Clements, C.S., Bharadwaj, M., Kjer-Nielsen, L., Saunders, P.M., Wilce, M.C., Crawford, F., Stadinsky, B., Jackson, D., Brooks, A.G., Purcell, A.W., Kappler, J.W., Burrows, S.R., Rossjohn, J., McCluskey, J.
Deposit date:2009-11-16
Release date:2009-12-22
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:T cell allorecognition via molecular mimicry.
Immunity, 31, 2009
3KPQ
  • Download 3kpq
  • View 3kpq
Molmil generated image of 3kpq
CRYSTAL STRUCTURE OF HLA B*4405 IN COMPLEX WITH EEYLKAWTF, A MIMOTOPE
Descriptor:HLA class I histocompatibility antigen, B-44 alpha chain, Beta-2-microglobulin, ...
Authors:Macdonald, W.A., Chen, Z., Gras, S., Archbold, J.K., Tynan, F.E., Clements, C.S., Bharadwaj, M., Kjer-Nielsen, L., Saunders, P.M., Wilce, M.C., Crawford, F., Stadinsky, B., Jackson, D., Brooks, A.G., Purcell, A.W., Kappler, J.W., Burrows, S.R., Rossjohn, J., McCluskey, J.
Deposit date:2009-11-16
Release date:2009-12-22
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:T cell allorecognition via molecular mimicry.
Immunity, 31, 2009
3KPR
  • Download 3kpr
  • View 3kpr
Molmil generated image of 3kpr
CRYSTAL STRUCTURE OF THE LC13 TCR IN COMPLEX WITH HLA B*4405 BOUND TO EEYLKAWTF A MIMOTOPE
Descriptor:HLA class I histocompatibility antigen, B-44 alpha chain, Beta-2-microglobulin, ...
Authors:Macdonald, W.A., Chen, Z., Gras, S., Archbold, J.K., Tynan, F.E., Clements, C.S., Bharadwaj, M., Kjer-Nielsen, L., Saunders, P.M., Wilce, M.C., Crawford, F., Stadinsky, B., Jackson, D., Brooks, A.G., Purcell, A.W., Kappler, J.W., Burrows, S.R., Rossjohn, J., McCluskey, J.
Deposit date:2009-11-16
Release date:2009-12-22
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:T cell allorecognition via molecular mimicry.
Immunity, 31, 2009
3KPS
  • Download 3kps
  • View 3kps
Molmil generated image of 3kps
CRYSTAL STRUCTURE OF THE LC13 TCR IN COMPLEX WITH HLA B*4405 BOUND TO EEYLQAFTY A SELF PEPTIDE FROM THE ABCD3 PROTEIN
Descriptor:HLA class I histocompatibility antigen, B-44 alpha chain, Beta-2-microglobulin, ...
Authors:Macdonald, W.A., Chen, Z., Gras, S., Archbold, J.K., Tynan, F.E., Clements, C.S., Bharadwaj, M., Kjer-Nielsen, L., Saunders, P.M., Wilce, M.C., Crawford, F., Stadinsky, B., Jackson, D., Brooks, A.G., Purcell, A.W., Kappler, J.W., Burrows, S.R., Rossjohn, J., McCluskey, J.
Deposit date:2009-11-16
Release date:2009-12-22
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:T cell allorecognition via molecular mimicry.
Immunity, 31, 2009
3LD8
  • Download 3ld8
  • View 3ld8
Molmil generated image of 3ld8
STRUCTURE OF JMJD6 AND FAB FRAGMENTS
Descriptor:Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6, antibody Fab fragment light chain, antibody Fab fragment heavy chain, ...
Authors:Hong, X., Zang, J., White, J., Kappler, J.W., Wang, C., Zhang, G.
Deposit date:2010-01-12
Release date:2010-08-04
Last modified:2012-06-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Interaction of JMJD6 with single-stranded RNA.
Proc.Natl.Acad.Sci.USA, 107, 2010
3LDB
  • Download 3ldb
  • View 3ldb
Molmil generated image of 3ldb
STRUCTURE OF JMJD6 COMPLEXD WITH ALPHA-KETOGLUTARATE AND FAB FRAGMENT.
Descriptor:Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6, antibody Fab fragment light chain, antibody Fab fragment heavy chain, ...
Authors:Hong, X., Zang, J., White, J., Kappler, J.W., Wang, C., Zhang, G.
Deposit date:2010-01-12
Release date:2010-08-04
Last modified:2012-06-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Interaction of JMJD6 with single-stranded RNA.
Proc.Natl.Acad.Sci.USA, 107, 2010
3RGV
  • Download 3rgv
  • View 3rgv
Molmil generated image of 3rgv
A SINGLE TCR BOUND TO MHCI AND MHC II REVEALS SWITCHABLE TCR CONFORMERS
Descriptor:Yae62 TCR a chain, Yae62 TCR b chain, H-2 class I histocompatibility antigen, ...
Authors:Dai, S., Huseby, E., Scott-Browne, J., Rubtsova, K., Pinilla, C., Crawford, F., Marrack, P., Yin, L., Kappler, J.W.
Deposit date:2011-04-09
Release date:2011-07-20
Last modified:2011-08-03
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:A Single T Cell Receptor Bound to Major Histocompatibility Complex Class I and Class II Glycoproteins Reveals Switchable TCR Conformers.
Immunity, 35, 2011
4P4K
  • Download 4p4k
  • View 4p4k
Molmil generated image of 4p4k
STRUCTURAL BASIS OF CHRONIC BERYLLIUM DISEASE: BRIDGING THE GAP BETWEEN ALLERGIC HYPERSENSITIVITY AND AUTO IMMUNITY
Descriptor:HLA class II histocompatibility antigen, DP alpha 1 chain, mim2 peptide,HLA class II histocompatibility antigen, ...
Authors:Clayton, G.M., Crawford, F., Kappler, J.W.
Deposit date:2014-03-12
Release date:2014-07-16
Last modified:2015-01-07
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis of chronic beryllium disease: linking allergic hypersensitivity and autoimmunity.
Cell, 158, 2014
4P4R
  • Download 4p4r
  • View 4p4r
Molmil generated image of 4p4r
STRUCTURAL BASIS OF CHRONIC BERYLLIUM DISEASE: BRIDGING THE GAP BETWEEN ALLERGIC HYPERSENSITIVITY AND AUTOIMMUNITY
Descriptor:HLA class II histocompatibility antigen, DP alpha 1 chain, mim2 peptide,HLA class II histocompatibility antigen, ...
Authors:Clayton, G.M., Crawford, F., Kappler, J.W.
Deposit date:2014-03-13
Release date:2014-07-16
Last modified:2015-01-07
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis of chronic beryllium disease: linking allergic hypersensitivity and autoimmunity.
Cell, 158, 2014
4P57
  • Download 4p57
  • View 4p57
Molmil generated image of 4p57
MHC TCR PEPTIDE COMPLEX
Descriptor:HLA class II histocompatibility antigen, DP alpha 1 chain, mim2 peptide,HLA class II histocompatibility antigen, ...
Authors:Clayton, G.M., Crawford, F., Kappler, J.W.
Deposit date:2014-03-14
Release date:2014-07-16
Last modified:2015-01-07
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis of chronic beryllium disease: linking allergic hypersensitivity and autoimmunity.
Cell, 158, 2014
4P5K
  • Download 4p5k
  • View 4p5k
Molmil generated image of 4p5k
STRUCTURAL BASIS OF CHRONIC BERYLLIUM DISEASE: BRIDGING THE GAP BETWEEN ALLERGY AND AUTOIMMUNITY
Descriptor:HLA class II histocompatibility antigen, DP alpha 1 chain, RAS peptide,HLA class II histocompatibility antigen, ...
Authors:Clayton, G.M., Wang, Y., Crawford, F., Novikov, A., Wimberly, B.T., Kieft, J.S., Falta, M.T., Bowerman, N.A., Marrack, P., Fontenot, A.P., Dai, S., Kappler, J.W.
Deposit date:2014-03-17
Release date:2015-01-21
Last modified:2018-03-21
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Structural basis of chronic beryllium disease: linking allergic hypersensitivity and autoimmunity.
Cell, 158, 2014
5DMK
  • Download 5dmk
  • View 5dmk
Molmil generated image of 5dmk
CRYSTAL STRUCTURE OF IAG7 IN COMPLEX WITH RLGL-WE14
Descriptor:H-2 class II histocompatibility antigen, A-D alpha chain, beta chain of Major Histocompatibility Complex Class II, ...
Authors:Wang, Y., Jin, N., Dai, S., Kappler, J.W.
Deposit date:2015-09-08
Release date:2015-10-28
Last modified:2016-04-06
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:N-terminal additions to the WE14 peptide of chromogranin A create strong autoantigen agonists in type 1 diabetes.
Proc.Natl.Acad.Sci.USA, 112, 2015
1I3R
  • Download 1i3r
  • View 1i3r
Molmil generated image of 1i3r
CRYSTAL STRUCTURE OF A MUTANT IEK CLASS II MHC MOLECULE
Descriptor:H-2 CLASS II HISTOCOMPATIBILITY ANTIGEN, E-K ALPHA CHAIN, FUSION PROTEIN CONSISTING OF MHC E-BETA-K PRECURSOR, ...
Authors:Kappler, J.W., Wilson, N.
Deposit date:2001-02-15
Release date:2001-06-20
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Mutations changing the kinetics of class II MHC peptide exchange.
Immunity, 14, 2001
3C5Z
  • Download 3c5z
  • View 3c5z
Molmil generated image of 3c5z
CRYSTAL STRUCTURE OF MOUSE MHC CLASS II I-AB/3K PEPTIDE COMPLEXED WITH MOUSE TCR B3K506
Descriptor:TCR B3K506 Alpha Chain, TCR B3K506 Beta Chain, H-2 class II histocompatibility antigen, ...
Authors:Dai, S., Kappler, J.
Deposit date:2008-02-01
Release date:2008-04-29
Last modified:2017-08-16
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Crossreactive T Cells spotlight the germline rules for alphabeta T cell-receptor interactions with MHC molecules.
Immunity, 28, 2008
<12>