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1A7F
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INSULIN MUTANT B16 GLU, B24 GLY, DES-B30, NMR, 20 STRUCTURES
Descriptor:INSULIN
Authors:Ludvigsen, S., Kaarsholm, N.C.
Deposit date:1998-03-12
Release date:1998-07-15
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:A structural switch in a mutant insulin exposes key residues for receptor binding.
J.Mol.Biol., 279, 1998
1HLS
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NMR STRUCTURE OF THE HUMAN INSULIN-HIS(B16)
Descriptor:INSULIN
Authors:Ludvigsen, S., Kaarsholm, N.C.
Deposit date:1995-06-28
Release date:1995-09-15
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:High-resolution structure of an engineered biologically potent insulin monomer, B16 Tyr-->His, as determined by nuclear magnetic resonance spectroscopy.
Biochemistry, 33, 1994
1HUI
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INSULIN MUTANT (B1, B10, B16, B27)GLU, DES-B30, NMR, 25 STRUCTURES
Descriptor:INSULIN
Authors:Olsen, H.B., Ludvigsen, S., Kaarsholm, N.C.
Deposit date:1996-03-29
Release date:1997-03-12
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Solution structure of an engineered insulin monomer at neutral pH.
Biochemistry, 35, 1996
1IOG
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INSULIN MUTANT A3 GLY,(B1, B10, B16, B27)GLU, DES-B30, NMR, 19 STRUCTURES
Descriptor:PROTEIN (INSULIN PRECURSOR)
Authors:Olsen, H.B., Ludvigsen, S., Kaarsholm, N.C.
Deposit date:1998-08-13
Release date:1999-01-13
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:The relationship between insulin bioactivity and structure in the NH2-terminal A-chain helix.
J.Mol.Biol., 284, 1998
1IOH
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INSULIN MUTANT A8 HIS,(B1, B10, B16, B27)GLU, DES-B30, NMR, 26 STRUCTURES
Descriptor:PROTEIN (INSULIN PRECURSOR)
Authors:Olsen, H.B., Ludvigsen, S., Kaarsholm, N.C.
Deposit date:1998-08-13
Release date:1999-01-13
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:The relationship between insulin bioactivity and structure in the NH2-terminal A-chain helix.
J.Mol.Biol., 284, 1998
1J73
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CRYSTAL STRUCTURE OF AN UNSTABLE INSULIN ANALOG WITH NATIVE ACTIVITY.
Descriptor:insulin a, insulin b, ZINC ION
Authors:Wan, Z., Zhao, M., Nakagawa, S., Jia, W., Weiss, M.A.
Deposit date:2001-05-15
Release date:2001-05-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Non-standard insulin design: structure-activity relationships at the periphery of the insulin receptor.
J.Mol.Biol., 315, 2002
1JCA
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NON-STANDARD DESIGN OF UNSTABLE INSULIN ANALOGUES WITH ENHANCED ACTIVITY
Descriptor:insulin a, insulin b, ZINC ION
Authors:Weiss, M.A., Wan, Z., Zhao, M., Chu, Y.-C., Nakagawa, S.H., Burke, G.T., Jia, W., Hellmich, R., Katsoyannis, P.G.
Deposit date:2001-06-08
Release date:2001-06-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Non-standard insulin design: structure-activity relationships at the periphery of the insulin receptor.
J.Mol.Biol., 315, 2002
1ZNI
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INSULIN
Descriptor:INSULIN, ZINC ION, CHLORIDE ION
Authors:Turkenburg, M.G.W., Whittingham, J.L., Dodson, G.G., Dodson, E.J., Xiao, B., Bentley, G.A.
Deposit date:1997-09-23
Release date:1998-01-28
Last modified:2018-07-04
Method:X-RAY DIFFRACTION (1.498 Å)
Cite:Structure of insulin in 4-zinc insulin.
Nature, 261, 1976