Author results

1B4E
  • Download 1b4e
  • View 1b4e
Molmil generated image of 1b4e
X-RAY STRUCTURE OF 5-AMINOLEVULINIC ACID DEHYDRATASE COMPLEXED WITH THE INHIBITOR LEVULINIC ACID
Descriptor:PROTEIN (5-AMINOLEVULINIC ACID DEHYDRATASE), SULFATE ION, ZINC ION, ...
Authors:Erskine, P.T., Cooper, J.B., Lewis, G., Spencer, P., Wood, S.P., Shoolingin-Jordan, P.M.
Deposit date:1998-12-19
Release date:1999-12-17
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:X-ray structure of 5-aminolevulinic acid dehydratase from Escherichia coli complexed with the inhibitor levulinic acid at 2.0 A resolution.
Biochemistry, 38, 1999
1E51
  • Download 1e51
  • View 1e51
Molmil generated image of 1e51
CRYSTAL STRUCTURE OF NATIVE HUMAN ERYTHROCYTE 5-AMINOLAEVULINIC ACID DEHYDRATASE
Descriptor:DELTA-AMINOLEVULINIC ACID DEHYDRATASE, 3-[5-(AMINOMETHYL)-4-(CARBOXYMETHYL)-1H-PYRROL-3-YL]PROPANOIC ACID, ZINC ION, ...
Authors:Mills-Davies, N.L., Thompson, D., Cooper, J.B., Shoolingin-Jordan, P.M.
Deposit date:2000-07-13
Release date:2001-07-12
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (2.83 Å)
Cite:The Crystal Structure of Human Ala-Dehydratase
To be Published
1EB3
  • Download 1eb3
  • View 1eb3
Molmil generated image of 1eb3
YEAST 5-AMINOLAEVULINIC ACID DEHYDRATASE 4,7-DIOXOSEBACIC ACID COMPLEX
Descriptor:5-AMINOLAEVULINIC ACID DEHYDRATASE, 4,7-DIOXOSEBACIC ACID, ZINC ION
Authors:Erskine, P.T., Coates, L., Newbold, R., Brindley, A.A., Stauffer, F., Wood, S.P., Warren, M.J., Cooper, J.B., Shoolingin-Jordan, P.M., Neier, R.
Deposit date:2001-07-18
Release date:2001-08-02
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:The X-Ray Structure of Yeast 5-Aminolaevulinic Acid Dehydratase Complexed with Two Diacid Inhibitors
FEBS Lett., 503, 2001
1GJP
  • Download 1gjp
  • View 1gjp
Molmil generated image of 1gjp
SCHIFF-BASE COMPLEX OF YEAST 5-AMINOLAEVULINIC ACID DEHYDRATASE WITH 4-OXOSEBACIC ACID
Descriptor:5-AMINOLAEVULINIC ACID DEHYDRATASE, 4-OXODECANEDIOIC ACID, ZINC ION
Authors:Erskine, P.T., Coates, L., Newbold, R., Brindley, A.A., Wood, S.P., Warren, M.J., Cooper, J.B., Shoolingin-Jordan, P.M., Neier, R.
Deposit date:2001-08-01
Release date:2001-08-02
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The X-Ray Structure of Yeast 5-Aminolaevulinic Acid Dehydratase Complexed with Two Diacid Inhibitors
FEBS Lett., 503, 2001
1H7N
  • Download 1h7n
  • View 1h7n
Molmil generated image of 1h7n
SCHIFF-BASE COMPLEX OF YEAST 5-AMINOLAEVULINIC ACID DEHYDRATASE WITH LAEVULINIC ACID AT 1.6 A RESOLUTION
Descriptor:5-AMINOLAEVULINIC ACID DEHYDRATASE, LAEVULINIC ACID, ZINC ION
Authors:Erskine, P.T., Newbold, R., Brindley, A.A., Wood, S.P., Shoolingin-Jordan, P.M., Warren, M.J., Cooper, J.B.
Deposit date:2001-07-09
Release date:2001-07-10
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The X-Ray Structure of Yeast 5-Aminolaevulinic Acid Dehydratase Complexed with Substrate and Three Inhibitors
J.Mol.Biol., 312, 2001
1H7O
  • Download 1h7o
  • View 1h7o
Molmil generated image of 1h7o
SCHIFF-BASE COMPLEX OF YEAST 5-AMINOLAEVULINIC ACID DEHYDRATASE WITH 5-AMINOLAEVULINIC ACID AT 1.7 A RESOLUTION
Descriptor:5-AMINOLAEVULINIC ACID DEHYDRATASE, DELTA-AMINO VALERIC ACID, ZINC ION
Authors:Erskine, P.T., Newbold, R., Brindley, A.A., Wood, S.P., Shoolingin-Jordan, P.M., Warren, M.J., Cooper, J.B.
Deposit date:2001-07-09
Release date:2001-07-10
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:The X-Ray Structure of Yeast 5-Aminolaevulinic Acid Dehydratase Complexed with Substrate and Three Inhibitors
J.Mol.Biol., 312, 2001
1H7P
  • Download 1h7p
  • View 1h7p
Molmil generated image of 1h7p
SCHIFF-BASE COMPLEX OF YEAST 5-AMINOLAEVULINIC ACID DEHYDRATASE WITH 4-KETO-5-AMINO-HEXANOIC (KAH) AT 1.64 A RESOLUTION
Descriptor:5-AMINOLAEVULINIC ACID DEHYDRATASE, 5-AMINO-4-HYDROXYHEXANOIC ACID, ZINC ION
Authors:Erskine, P.T., Newbold, R., Brindley, A.A., Wood, S.P., Shoolingin-Jordan, P.M., Warren, M.J., Cooper, J.B.
Deposit date:2001-07-09
Release date:2001-07-13
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:The X-Ray Structure of Yeast 5-Aminolaevulinic Acid Dehydratase Complexed with Substrate and Three Inhibitors
J.Mol.Biol., 312, 2001
1H7R
  • Download 1h7r
  • View 1h7r
Molmil generated image of 1h7r
SCHIFF-BASE COMPLEX OF YEAST 5-AMINOLAEVULINIC ACID DEHYDRATASE WITH SUCCINYLACETONE AT 2.0 A RESOLUTION.
Descriptor:5-AMINOLAEVULINIC ACID DEHYDRATASE, 4,6-DIOXOHEPTANOIC ACID, ZINC ION
Authors:Erskine, P.T., Newbold, R., Brindley, A.A., Wood, S.P., Shoolingin-Jordan, P.M., Warren, M.J., Cooper, J.B.
Deposit date:2001-07-09
Release date:2001-07-12
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:The X-Ray Structure of Yeast 5-Aminolaevulinic Acid Dehydratase Complexed with Substrate and Three Inhibitors
J.Mol.Biol., 312, 2001
1OHL
  • Download 1ohl
  • View 1ohl
Molmil generated image of 1ohl
YEAST 5-AMINOLAEVULINIC ACID DEHYDRATASE PUTATIVE CYCLIC REACTION INTERMEDIATE COMPLEX
Descriptor:DELTA-AMINOLEVULINIC ACID DEHYDRATASE, ZINC ION, BETA-MERCAPTOETHANOL, ...
Authors:Erskine, P.T., Coates, L., Butler, D., Youell, J.H., Brindley, A.A., Wood, S.P., Warren, M.J., Shoolingin-Jordan, P.M., Cooper, J.B.
Deposit date:2003-05-27
Release date:2003-06-02
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:X-Ray Structure of a Putative Reaction Intermediateof 5-Aminolaevulinic Acid Dehydratase
Biochem.J., 373, 2003
1PDA
  • Download 1pda
  • View 1pda
Molmil generated image of 1pda
STRUCTURE OF PORPHOBILINOGEN DEAMINASE REVEALS A FLEXIBLE MULTIDOMAIN POLYMERASE WITH A SINGLE CATALYTIC SITE
Descriptor:PORPHOBILINOGEN DEAMINASE, 3-[5-{[3-(2-carboxyethyl)-4-(carboxymethyl)-5-methyl-1H-pyrrol-2-yl]methyl}-4-(carboxymethyl)-1H-pyrrol-3-yl]propanoic acid, ACETIC ACID
Authors:Louie, G.V., Brownlie, P.D., Lambert, R., Cooper, J.B., Blundell, T.L., Wood, S.P., Warren, M.J., Woodcock, S.C., Jordan, P.M.
Deposit date:1992-11-17
Release date:1993-10-31
Last modified:2019-08-14
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Structure of porphobilinogen deaminase reveals a flexible multidomain polymerase with a single catalytic site.
Nature, 359, 1992
1W31
  • Download 1w31
  • View 1w31
Molmil generated image of 1w31
YEAST 5-AMINOLAEVULINIC ACID DEHYDRATASE 5-HYDROXYLAEVULINIC ACID COMPLEX
Descriptor:DELTA-AMINOLEVULINIC ACID DEHYDRATASE, 5-HYDROXYLAEVULINIC ACID, ZINC ION
Authors:Erskine, P.T., Coates, L., Newbold, R., Brindley, A.A., Stauffer, F., Beaven, G.D.E., Gill, R., Wood, S.P., Warren, M.J., Cooper, J.B., Shoolingin-Jordan, P.M., Neier, R.
Deposit date:2004-07-11
Release date:2005-08-23
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of Yeast 5-Aminolaevulinic Acid Dehydratase Complexed with the Inhibitor 5-Hydroxylaevulinic Acid
Acta Crystallogr.,Sect.D, 61, 2005
1YLV
  • Download 1ylv
  • View 1ylv
Molmil generated image of 1ylv
SCHIFF-BASE COMPLEX OF YEAST 5-AMINOLAEVULINIC ACID DEHYDRATASE WITH LAEVULINIC ACID
Descriptor:PROTEIN (5-AMINOLAEVULINIC ACID DEHYDRATASE), ZINC ION, LAEVULINIC ACID
Authors:Erskine, P.T., Newbold, R., Roper, J., Coker, A., Warren, M.J., Shoolingin-Jordan, P.M., Wood, S.P., Cooper, J.B.
Deposit date:1999-02-22
Release date:2000-02-23
Last modified:2018-04-11
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:The Schiff base complex of yeast 5-aminolaevulinic acid dehydratase with laevulinic acid.
Protein Sci., 8, 1999
2C1H
  • Download 2c1h
  • View 2c1h
Molmil generated image of 2c1h
THE X-RAY STRUCTURE OF CHLOROBIUM VIBRIOFORME 5-AMINOLAEVULINIC ACID DEHYDRATASE COMPLEXED WITH A DIACID INHIBITOR
Descriptor:DELTA-AMINOLEVULINIC ACID DEHYDRATASE, MAGNESIUM ION, 4,7-DIOXOSEBACIC ACID
Authors:Coates, L., Beaven, G., Erskine, P.T., Beale, S., Wood, S.P., Shoolingin-Jordan, P.M., Cooper, J.B.
Deposit date:2005-09-14
Release date:2005-12-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of Chlorobium Vibrioforme 5-Aminolaevulinic Acid Dehydratase Complexed with a Diacid Inhibitor.
Acta Crystallogr.,Sect.D, 61, 2005
4HTG
  • Download 4htg
  • View 4htg
Molmil generated image of 4htg
PORPHOBILINOGEN DEAMINASE FROM ARABIDOPSIS THALIANA
Descriptor:Porphobilinogen deaminase, chloroplastic, 3-[(5Z)-5-{[3-(2-carboxyethyl)-4-(carboxymethyl)-5-methyl-1H-pyrrol-2-yl]methylidene}-4-(carboxymethyl)-2-oxo-2,5-dihydro-1H-pyrrol-3-yl]propanoic acid, ...
Authors:Roberts, A., Gill, R., Hussey, R.J., Erskine, P.T., Cooper, J.B., Wood, S.P., Chrystal, E.J.T., Shoolingin-Jordan, P.M.
Deposit date:2012-11-01
Release date:2013-02-27
Last modified:2013-04-03
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Insights into the mechanism of pyrrole polymerization catalysed by porphobilinogen deaminase: high-resolution X-ray studies of the Arabidopsis thaliana enzyme.
Acta Crystallogr.,Sect.D, 69, 2013
5HMS
  • Download 5hms
  • View 5hms
Molmil generated image of 5hms
X-RAY STRUCTURE OF HUMAN RECOMBINANT 5-AMINOLAEVULINIC ACID DEHYDRATASE (HRALAD).
Descriptor:Delta-aminolevulinic acid dehydratase, ZINC ION
Authors:Butler, D., Erskine, P.T., Cooper, J.B., Shoolingin-Jordan, P.M.
Deposit date:2016-01-17
Release date:2016-01-27
Last modified:2017-03-01
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural studies of substrate and product complexes of 5-aminolaevulinic acid dehydratase from humans, Escherichia coli and the hyperthermophile Pyrobaculum calidifontis.
Acta Crystallogr D Struct Biol, 73, 2017
5HNR
  • Download 5hnr
  • View 5hnr
Molmil generated image of 5hnr
THE X-RAY STRUCTURE OF OCTAMERIC HUMAN NATIVE 5-AMINOLAEVULINIC ACID DEHYDRATASE.
Descriptor:Delta-aminolevulinic acid dehydratase, ZINC ION, SULFATE ION, ...
Authors:Mills-Davies, N.L., Thompson, D., Shoolingin-Jordan, P.M., Erskine, P.T., Cooper, J.B.
Deposit date:2016-01-18
Release date:2016-01-27
Last modified:2017-01-25
Method:X-RAY DIFFRACTION (2.83 Å)
Cite:Structural studies of substrate and product complexes of 5-aminolaevulinic acid dehydratase from humans, Escherichia coli and the hyperthermophile Pyrobaculum calidifontis.
Acta Crystallogr D Struct Biol, 73, 2017
5MHB
  • Download 5mhb
  • View 5mhb
Molmil generated image of 5mhb
PRODUCT-COMPLEX OF E.COLI 5-AMINO LAEVULINIC ACID DEHYDRATASE
Descriptor:Delta-aminolevulinic acid dehydratase, 3-[5-(AMINOMETHYL)-4-(CARBOXYMETHYL)-1H-PYRROL-3-YL]PROPANOIC ACID, ZINC ION, ...
Authors:Norton, E., Erskine, P.T., Shoolingin-Jordan, P.M., Cooper, J.B.
Deposit date:2016-11-23
Release date:2016-12-07
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural studies of substrate and product complexes of 5-aminolaevulinic acid dehydratase from humans, Escherichia coli and the hyperthermophile Pyrobaculum calidifontis.
Acta Crystallogr D Struct Biol, 73, 2017
3K6M
  • Download 3k6m
  • View 3k6m
Molmil generated image of 3k6m
DYNAMIC DOMAINS OF SUCCINYL-COA:3-KETOACID-COENZYME A TRANSFERASE FROM PIG HEART.
Descriptor:Succinyl-CoA:3-ketoacid-coenzyme A transferase 1, mitochondrial, CHLORIDE ION, ...
Authors:Coker, S., Lloyd, A., Mitchell, E., Lewis, G.R., Shoolingin-Jordan, P., Coker, A.R.
Deposit date:2009-10-09
Release date:2010-07-07
Last modified:2012-03-21
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The high-resolution structure of pig heart succinyl-CoA:3-oxoacid coenzyme A transferase.
Acta Crystallogr.,Sect.D, 66, 2010
1AW5
  • Download 1aw5
  • View 1aw5
Molmil generated image of 1aw5
5-AMINOLEVULINATE DEHYDRATASE FROM SACCHAROMYCES CEREVISIAE
Descriptor:5-AMINOLEVULINATE DEHYDRATASE, ZINC ION
Authors:Erskine, P.T., Cooper, J.B., Wood, S.P.
Deposit date:1997-10-09
Release date:1998-10-21
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:X-ray structure of 5-aminolaevulinate dehydratase, a hybrid aldolase.
Nat.Struct.Biol., 4, 1997
1B4K
  • Download 1b4k
  • View 1b4k
Molmil generated image of 1b4k
HIGH RESOLUTION CRYSTAL STRUCTURE OF A MG2-DEPENDENT 5-AMINOLEVULINIC ACID DEHYDRATASE
Descriptor:PROTEIN (5-AMINOLEVULINIC ACID DEHYDRATASE), SULFATE ION, MAGNESIUM ION, ...
Authors:Frankenberg, N., Jahn, D., Heinz, D.W.
Deposit date:1998-12-22
Release date:1999-07-13
Last modified:2012-01-18
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:High resolution crystal structure of a Mg2+-dependent porphobilinogen synthase.
J.Mol.Biol., 289, 1999
2IPH
  • Download 2iph
  • View 2iph
Molmil generated image of 2iph
X-RAY STRUCTURE AT 1.75 A RESOLUTION OF A NOROVIRUS PROTEASE LINKED TO AN ACTIVE SITE DIRECTED PEPTIDE INHIBITOR
Descriptor:Thiol protease P3C, N-ACETYL-L-ALPHA-GLUTAMYL-L-PHENYLALANYL-L-GLUTAMINYL-N-[(1S)-4-AMINO-1-(2-CARBOXYETHYL)-4-OXOBUTYL]-L-LEUCINAMIDE
Authors:Hussey, R.J.
Deposit date:2006-10-12
Release date:2007-10-23
Last modified:2012-06-20
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:A Structural Study of Norovirus 3C Protease Specificity: Binding of a Designed Active Site-Directed Peptide Inhibitor.
Biochemistry, 50, 2011
3EQ1
  • Download 3eq1
  • View 3eq1
Molmil generated image of 3eq1
THE CRYSTAL STRUCTURE OF HUMAN PORPHOBILINOGEN DEAMINASE AT 2.8A RESOLUTION
Descriptor:Porphobilinogen deaminase, 3-[5-{[3-(2-carboxyethyl)-4-(carboxymethyl)-5-methyl-1H-pyrrol-2-yl]methyl}-4-(carboxymethyl)-1H-pyrrol-3-yl]propanoic acid, SULFATE ION
Authors:Kolstoe, S.E., Gill, R., Mohammed, F., Wood, S.P.
Deposit date:2008-09-30
Release date:2009-03-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of human porphobilinogen deaminase at 2.8 A: the molecular basis of acute intermittent porphyria
Biochem.J., 420, 2009
5LZL
  • Download 5lzl
  • View 5lzl
Molmil generated image of 5lzl
PYROBACULUM CALIDIFONTIS 5-AMINOLAEVULINIC ACID DEHYDRATASE
Descriptor:Delta-aminolevulinic acid dehydratase, ZINC ION
Authors:Azim, N., Erskine, P.T., Guo, J., Cooper, J.B.
Deposit date:2016-09-30
Release date:2016-10-12
Last modified:2019-07-10
Method:X-RAY DIFFRACTION (3.47 Å)
Cite:Structural studies of substrate and product complexes of 5-aminolaevulinic acid dehydratase from humans, Escherichia coli and the hyperthermophile Pyrobaculum calidifontis.
Acta Crystallogr D Struct Biol, 73, 2017