Author results

4BCS
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CRYSTAL STRUCTURE OF AN AVIDIN MUTANT
Descriptor:CHIMERIC AVIDIN, ACETATE ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Airenne, T.T., Niederhauser, B., Hytonen, V.P., Kulomaa, M.S., Johnson, M.S.
Deposit date:2012-10-03
Release date:2013-10-16
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A Novel Chimeric Avidin with Increased Thermal Stability Using DNA Shuffling.
Plos One, 9, 2014
1WBI
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AVR2
Descriptor:AVIDIN-RELATED PROTEIN 2, BIOTIN, GLYCEROL, ...
Authors:Airenne, T.T., Hytonen, V.P., Maatta, J.H., Kidron, H., Halling, K.K., Horha, J., Kulomaa, T., Nyholm, T.K.M., Johnson, M.S., Salminen, T.A., Kulomaa, M.S.
Deposit date:2004-11-01
Release date:2005-10-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Avidin Related Protein 2 Shows Unique Structural and Functional Features Among the Avidin Protein Family.
Bmc Biotechnol., 5, 2005
2C1Q
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X-RAY STRUCTURE OF BIOTIN BINDING PROTEIN FROM CHICKEN
Descriptor:BIOTIN BINDING PROTEIN A, BIOTIN, GLYCEROL
Authors:Hytonen, V.P., Niskanen, E.A., Maatta, J.A.E., Huuskonen, J., Helttunen, K.J., Halling, K.K., Slotte, J.P., Nordlund, H.R., Rissanen, K., Johnson, M.S., Salminen, T.A., Kulomaa, M.S., Laitinen, O.H., Airenne, T.T.
Deposit date:2005-09-19
Release date:2007-02-20
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure and Characterization of a Novel Chicken Biotin-Binding Protein a (Bbp-A).
Bmc Struct.Biol., 7, 2007
2C1S
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X-RAY STRUCTURE OF BIOTIN BINDING PROTEIN FROM CHICKEN
Descriptor:BIOTIN BINDING PROTEIN A, BIOTIN-D-SULFOXIDE
Authors:Hytonen, V.P., Niskanen, E.A., Maatta, J.A.E., Huuskonen, J., Helttunen, K.J., Halling, K.K., Slotte, J.P., Nordlund, H.R., Rissanen, K., Johnson, M.S., Salminen, T.A., Kulomaa, M.S., Laitinen, O.H., Airenne, T.T.
Deposit date:2005-09-19
Release date:2007-02-13
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structure and Characterization of a Novel Chicken Biotin-Binding Protein a (Bbp-A).
Bmc Struct.Biol., 7, 2007
2C4I
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CRYSTAL STRUCTURE OF ENGINEERED AVIDIN
Descriptor:AVIDIN, BIOTIN, SULFATE ION
Authors:Hytonen, V.P., Horha, J., Airenne, T.T., Niskanen, E.A., Helttunen, K., Johnson, M.S., Salminen, T.A., Kulomaa, M.S., Nordlund, H.R.
Deposit date:2005-10-19
Release date:2006-07-05
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Controlling Quaternary Structure Assembly: Subunit Interface Engineering and Crystal Structure of Dual Chain Avidin.
J.Mol.Biol., 359, 2006
2JGS
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CIRCULAR PERMUTANT OF AVIDIN
Descriptor:CIRCULAR PERMUTANT OF AVIDIN, BIOTIN
Authors:Maatta, J.A.E., Hytonen, V.P., Airenne, T.T., Niskanen, E., Johnson, M.S., Kulomaa, M.S., Nordlund, H.R.
Deposit date:2007-02-14
Release date:2008-03-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Rational Modification of Ligand-Binding Preference of Avidin by Circular Permutation and Mutagenesis.
Chembiochem, 9, 2008
2UYW
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CRYSTAL STRUCTURE OF XENAVIDIN
Descriptor:XENAVIDIN, BIOTIN, FORMIC ACID
Authors:Helppolainen, S.H., Maatta, J.A.E., Airenne, T.T., Johnson, M.S., Kulomaa, M.S., Nordlund, H.R.
Deposit date:2007-04-20
Release date:2008-05-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural and Functional Characteristics of Xenavidin, the First Frog Avidin from Xenopus Tropicalis.
Bmc Struct.Biol., 9, 2009
2UZ2
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CRYSTAL STRUCTURE OF XENAVIDIN
Descriptor:XENAVIDIN, ACETATE ION, BIOTIN
Authors:Helppolainen, S.H., Maatta, J.A.E., Airenne, T.T., Johnson, M.S., Kulomaa, M.S., Nordlund, H.R.
Deposit date:2007-04-24
Release date:2008-06-03
Last modified:2017-06-28
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural and Functional Characteristics of Xenavidin, the First Frog Avidin from Xenopus Tropicalis.
Bmc Struct.Biol., 9, 2009
2Y32
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CRYSTAL STRUCTURE OF BRADAVIDIN
Descriptor:BLR5658 PROTEIN
Authors:Leppiniemi, J., Gronroos, T., Johnson, M.S., Kulomaa, M.S., Hytonen, V.P., Airenne, T.T.
Deposit date:2010-12-17
Release date:2011-12-28
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Structure of Bradavidin - C-Terminal Residues Act as Intrinsic Ligands.
Plos One, 7, 2012
4BBO
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CRYSTAL STRUCTURE OF CORE-BRADAVIDIN
Descriptor:BLR5658 PROTEIN, BIOTIN, GLYCEROL, ...
Authors:Airenne, T.T., Johnson, M.S., Maatta, J.A.E., Hytonen, V.H., Kulomaa, M.S.
Deposit date:2012-09-27
Release date:2013-10-16
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal Structure of Core-Bradavidin
To be Published
4BJ8
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ZEBAVIDIN
Descriptor:ZEBAVIDIN, BIOTIN, GLYCEROL
Authors:Airenne, T.T., Parthiban, M., Niederhauser, B., Zmurko, J., Kulomaa, M.S., Hytonen, V.P., Johnson, M.S.
Deposit date:2013-04-17
Release date:2013-11-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Zebavidin
Plos One, 8, 2013
4U46
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CRYSTAL STRUCTURE OF AN AVIDIN MUTANT
Descriptor:Avidin, CHLORIDE ION
Authors:Agrawal, N., Lehtonen, S., Kahkonen, N., Riihimaki, T., Hytonen, V.P., Kulomaa, M.S., Johnson, M.S., Airenne, T.T.
Deposit date:2014-07-23
Release date:2015-08-05
Last modified:2016-09-28
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Artificial Avidin-Based Receptors for a Panel of Small Molecules.
Acs Chem.Biol., 11, 2016
5LUR
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AN AVIDIN MUTANT
Descriptor:Avidin, PROGESTERONE, CHLORIDE ION
Authors:Agrawal, N., Lehtonen, S.I., Riihimaki, T.A., Kulomaa, M.S., Hytonen, V.P., Johnson, M.S., Airenne, T.T.
Deposit date:2016-09-09
Release date:2017-09-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:An avidin mutant
TO BE PUBLISHED
1US1
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CRYSTAL STRUCTURE OF HUMAN VASCULAR ADHESION PROTEIN-1
Descriptor:MEMBRANE COPPER AMINE OXIDASE, COPPER (II) ION, CALCIUM ION, ...
Authors:Airenne, T.T., Nymalm, Y., Kidron, H., Soderholm, A., Johnson, M.S., Salminen, T.A.
Deposit date:2003-11-17
Release date:2005-02-16
Last modified:2018-02-28
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal Structure of the Human Vascular Adhesion Protein-1: Unique Structural Features with Functional Implications.
Protein Sci., 14, 2005
1VYO
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CRYSTAL STRUCTURE OF AVIDIN
Descriptor:AVIDIN, GLYCEROL
Authors:Airenne, T.T., Johnson, M.S., Salminen, T.A.
Deposit date:2004-05-03
Release date:2005-07-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Binding Properties of Haba-Type Azo Derivatives to Avidin and Avidin-Related Protein 4.
Chem.Biol., 13, 2006
1F6L
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VARIABLE LIGHT CHAIN DIMER OF ANTI-FERRITIN ANTIBODY
Descriptor:ANTI-FERRITIN IMMUNOGLOBULIN LIGHT CHAIN
Authors:Nymalm, Y., Kravchuk, Z., Salminen, T., Chumanevich, A.A., Dubnovitsky, A.P., Kankare, J., Pentikainen, O., Lehtonen, J., Arosio, P., Martsev, S., Johnson, M.S.
Deposit date:2000-06-22
Release date:2002-10-23
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Antiferritin VL homodimer binds human spleen ferritin with high specificity
J.STRUCT.BIOL., 138, 2002
1PT6
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I DOMAIN FROM HUMAN INTEGRIN ALPHA1-BETA1
Descriptor:Integrin alpha-1, MAGNESIUM ION, GLYCEROL
Authors:Nymalm, Y., Puranen, J.S., Nyholm, T.K.M., Kapyla, J., Kidron, H., Pentikainen, O., Airenne, T.T., Heino, J., Slotte, J.P., Johnson, M.S., Salminen, T.A.
Deposit date:2003-06-23
Release date:2004-04-13
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Jararhagin-derived RKKH peptides induce structural changes in alpha1I domain of human integrin alpha1beta1.
J.Biol.Chem., 279, 2004
1QCY
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THE CRYSTAL STRUCTURE OF THE I-DOMAIN OF HUMAN INTEGRIN ALPHA1BETA1
Descriptor:I-DOMAIN OF INTEGRIN ALPHA1BETA1, MAGNESIUM ION
Authors:Kankare, J.A., Salminen, T.A., Nymalm, Y., Kaepylae, J., Heino, J., Johnson, M.S.
Deposit date:1999-05-12
Release date:2003-09-02
Last modified:2014-11-12
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Jararhagin-derived RKKH Peptides Induce Structural Changes in a1I Domain of Human Integrin a1b1
J.Biol.Chem., 279, 2004
2JXR
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STRUCTURE OF YEAST PROTEINASE A
Descriptor:PROTEINASE A, N-(morpholin-4-ylcarbonyl)-L-phenylalanyl-N-[(1R)-1-(cyclohexylmethyl)-3,3-difluoro-2,2-dihydroxy-4-(methylamino)-4-oxobutyl]-L-norleucinamide, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Aguilar, C.F., Badasso, M., Dreyer, T., Cronin, N.B., Newman, M.P., Cooper, J.B., Hoover, D.J., Wood, S.P., Johnson, M.S., Blundell, T.L.
Deposit date:1997-04-24
Release date:1997-10-29
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The three-dimensional structure at 2.4 A resolution of glycosylated proteinase A from the lysosome-like vacuole of Saccharomyces cerevisiae.
J.Mol.Biol., 267, 1997
1PU4
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CRYSTAL STRUCTURE OF HUMAN VASCULAR ADHESION PROTEIN-1
Descriptor:Membrane copper amine oxidase, N-ACETYL-D-GLUCOSAMINE, COPPER (II) ION, ...
Authors:Salminen, T.A., Airenne, T.T.
Deposit date:2003-06-24
Release date:2005-05-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal structure of the human vascular adhesion protein-1: unique structural features with functional implications.
Protein Sci., 14, 2005
5K7K
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DESIGN AND OPTIMIZATION OF BIARYL ETHER ARYL SULFONAMIDES AS SELECTIVE INHIBITORS OF NAV1.7: DISCOVERY OF CLINICAL CANDIDATE PF-05089771
Descriptor:Cytochrome P450 2C9, PROTOPORPHYRIN IX CONTAINING FE, 4-[4-chloranyl-2-(1~{H}-pyrazol-4-yl)phenoxy]-3-cyano-~{N}-(1,3-thiazol-2-yl)benzenesulfonamide
Authors:Swain, N., Chrencik, J.
Deposit date:2016-05-26
Release date:2017-06-07
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Discovery of Clinical Candidate 4-[2-(5-Amino-1H-pyrazol-4-yl)-4-chlorophenoxy]-5-chloro-2-fluoro-N-1,3-thiazol-4-ylbenzenesulfonamide (PF-05089771): Design and Optimization of Diaryl Ether Aryl Sulfonamides as Selective Inhibitors of NaV1.7.
J. Med. Chem., 60, 2017
6CEQ
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THE AER2 RECEPTOR FROM VIBRIO CHOLERAE IS A DUAL PAS-HEME OXYGEN SENSOR
Descriptor:Methyl-accepting chemotaxis protein, PROTOPORPHYRIN IX CONTAINING FE
Authors:Crane, B.R., Chua, T.K., Sukomon, N.
Deposit date:2018-02-12
Release date:2018-05-16
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:THE AER2 RECEPTOR FROM VIBRIO CHOLERAE IS A DUAL PAS-HEME OXYGEN SENSOR.
Mol. Microbiol., 2018
1DP5
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THE STRUCTURE OF PROTEINASE A COMPLEXED WITH A IA3 MUTANT INHIBITOR
Descriptor:PROTEINASE A, PROTEINASE INHIBITOR IA3, BETA-D-MANNOSE, ...
Authors:Li, M., Phylip, H.L., Lees, W.E., Winther, J.R., Dunn, B.M., Wlodawer, A., Kay, J., Guschina, A.
Deposit date:1999-12-23
Release date:2000-05-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The aspartic proteinase from Saccharomyces cerevisiae folds its own inhibitor into a helix.
Nat.Struct.Biol., 7, 2000
1DPJ
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THE STRUCTURE OF PROTEINASE A COMPLEXED WITH IA3 PEPTIDE INHIBITOR
Descriptor:PROTEINASE A, PROTEINASE INHIBITOR IA3 PEPTIDE, BETA-D-MANNOSE, ...
Authors:Li, M., Phylip, H.L., Lees, W.E., Winther, J.R., Dunn, B.M., Wlodawer, A., Kay, J., Guschina, A.
Deposit date:1999-12-27
Release date:2000-05-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The aspartic proteinase from Saccharomyces cerevisiae folds its own inhibitor into a helix.
Nat.Struct.Biol., 7, 2000
1FQ4
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CRYSTAL STRUCTURE OF A COMPLEX BETWEEN HYDROXYETHYLENE INHIBITOR CP-108,420 AND YEAST ASPARTIC PROTEINASE A
Descriptor:SACCHAROPEPSIN, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Cronin, N.B., Badasso, M.O., Tickle, I.J., Dreyer, T., Hoover, D.J., Rosati, R.L., Humblet, C.C., Lunney, E.A., Cooper, J.B.
Deposit date:2000-09-03
Release date:2000-09-20
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:X-ray structures of five renin inhibitors bound to saccharopepsin: exploration of active-site specificity.
J.Mol.Biol., 303, 2000
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