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1GPY
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CRYSTALLOGRAPHIC BINDING STUDIES ON THE ALLOSTERIC INHIBITOR GLUCOSE-6-PHOSPHATE TO T STATE GLYCOGEN PHOSPHORYLASE B
Descriptor:GLYCOGEN PHOSPHORYLASE B, ALPHA-D-GLUCOSE-6-PHOSPHATE, PYRIDOXAL-5'-PHOSPHATE
Authors:Johnson, L.N.
Deposit date:1993-03-31
Release date:1993-10-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystallographic binding studies on the allosteric inhibitor glucose-6-phosphate to T state glycogen phosphorylase b.
J.Mol.Biol., 232, 1993
1PKD
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THE CRYSTAL STRUCTURE OF UCN-01 IN COMPLEX WITH PHOSPHO-CDK2/CYCLIN A
Descriptor:Cell division protein kinase 2, Cyclin A2, 7-HYDROXYSTAUROSPORINE
Authors:Johnson, L.N., De Moliner, E., Brown, N.R., Song, H.
Deposit date:2003-06-05
Release date:2003-06-24
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The Crystal Structure of UCN-01 in Complex with Phospho-CDK2/Cyclin A
To be Published
1GPB
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GLYCOGEN PHOSPHORYLASE B: DESCRIPTION OF THE PROTEIN STRUCTURE
Descriptor:GLYCOGEN PHOSPHORYLASE B, PYRIDOXAL-5'-PHOSPHATE
Authors:Johnson, L.N., Acharya, K.R., Stuart, D.I.
Deposit date:1990-06-04
Release date:1992-10-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Glycogen Phosphorylase B: Description of the Protein Structure
Glycogen Phosphorylase B: Description of the Protein Structure, 1991
6GPB
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REFINED CRYSTAL STRUCTURE OF THE PHOSPHORYLASE-HEPTULOSE 2-PHOSPHATE-OLIGOSACCHARIDE-AMP COMPLEX
Descriptor:GLYCOGEN PHOSPHORYLASE B, HEPTULOSE-2-PHOSPHATE, ALPHA-D-GLUCOSE, ...
Authors:Acharya, K.R., Johnson, L.N.
Deposit date:1990-06-04
Release date:1992-10-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.86 Å)
Cite:Refined crystal structure of the phosphorylase-heptulose 2-phosphate-oligosaccharide-AMP complex.
J.Mol.Biol., 211, 1990
1NOI
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COMPLEX OF GLYCOGEN PHOSPHORYLASE WITH A TRANSITION STATE ANALOGUE NOJIRIMYCIN TETRAZOLE AND PHOSPHATE IN THE T AND R STATES
Descriptor:GLYCOGEN PHOSPHORYLASE, PHOSPHATE ION, PYRIDOXAL-5'-PHOSPHATE, ...
Authors:Johnson, L.N., Mitchell, E.P.
Deposit date:1996-03-12
Release date:1996-08-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Ternary complex crystal structures of glycogen phosphorylase with the transition state analogue nojirimycin tetrazole and phosphate in the T and R states.
Biochemistry, 35, 1996
1NOJ
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COMPLEX OF GLYCOGEN PHOSPHORYLASE WITH A TRANSITION STATE ANALOGUE NOJIRIMYCIN TETRAZOLE AND PHOSPHATE IN THE T STATE
Descriptor:GLYCOGEN PHOSPHORYLASE, PHOSPHATE ION, PYRIDOXAL-5'-PHOSPHATE, ...
Authors:Johnson, L.N., Mitchell, E.P.
Deposit date:1996-03-12
Release date:1996-07-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Ternary complex crystal structures of glycogen phosphorylase with the transition state analogue nojirimycin tetrazole and phosphate in the T and R states.
Biochemistry, 35, 1996
1NOK
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COMPLEX OF GLYCOGEN PHOSPHORYLASE WITH A TRANSITION STATE ANALOGUE NOJIRIMYCIN TETRAZOLE AND PHOSPHATE IN THE T STATE
Descriptor:GLYCOGEN PHOSPHORYLASE, PYRIDOXAL-5'-PHOSPHATE, NOJIRIMYCINE TETRAZOLE
Authors:Johnson, L.N., Mitchell, E.P.
Deposit date:1996-03-12
Release date:1996-07-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Ternary complex crystal structures of glycogen phosphorylase with the transition state analogue nojirimycin tetrazole and phosphate in the T and R states.
Biochemistry, 35, 1996
1LSY
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CRYSTAL STRUCTURE OF THE MUTANT D52S HEN EGG WHITE LYSOZYME WITH AN OLIGOSACCHARIDE PRODUCT
Descriptor:HEN EGG WHITE LYSOZYME
Authors:Johnson, L.N., Hadfield, A.T.
Deposit date:1994-09-27
Release date:1995-01-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of the mutant D52S hen egg white lysozyme with an oligosaccharide product.
J.Mol.Biol., 243, 1994
1LSZ
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CRYSTAL STRUCTURE OF THE MUTANT D52S HEN EGG WHITE LYSOZYME WITH AN OLIGOSACCHARIDE PRODUCT
Descriptor:HEN EGG WHITE LYSOZYME, 2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE, N-ACETYL-D-GLUCOSAMINE
Authors:Johnson, L.N., Hadfield, A.T.
Deposit date:1994-09-27
Release date:1995-01-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of the mutant D52S hen egg white lysozyme with an oligosaccharide product.
J.Mol.Biol., 243, 1994
1A8I
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SPIROHYDANTOIN INHIBITOR OF GLYCOGEN PHOSPHORYLASE
Descriptor:GLYCOGEN PHOSPHORYLASE B, BETA-D-GLUCOPYRANOSE SPIROHYDANTOIN
Authors:Gregoriou, M., Noble, M.E.M., Watson, K.A., Garman, E.F., Krulle, T.M., De La Fuente, C., Fleet, G.W.J., Oikonomakos, N.G., Johnson, L.N.
Deposit date:1998-03-25
Release date:1998-07-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:The structure of a glycogen phosphorylase glucopyranose spirohydantoin complex at 1.8 A resolution and 100 K: the role of the water structure and its contribution to binding.
Protein Sci., 7, 1998
1GPA
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STRUCTURAL MECHANISM FOR GLYCOGEN PHOSPHORYLASE CONTROL BY PHOSPHORYLATION AND AMP
Descriptor:GLYCOGEN PHOSPHORYLASE A, SULFATE ION, PYRIDOXAL-5'-PHOSPHATE
Authors:Barford, D., Hu, S.-H., Johnson, L.N.
Deposit date:1990-11-13
Release date:1992-10-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural mechanism for glycogen phosphorylase control by phosphorylation and AMP.
J.Mol.Biol., 218, 1991
2GPB
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COMPARISON OF THE BINDING OF GLUCOSE AND GLUCOSE-1-PHOSPHATE DERIVATIVES TO T-STATE GLYCOGEN PHOSPHORYLASE B
Descriptor:GLYCOGEN PHOSPHORYLASE B, ALPHA-D-GLUCOSE, PYRIDOXAL-5'-PHOSPHATE
Authors:Martin, J.L., Johnson, L.N.
Deposit date:1990-06-04
Release date:1992-10-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Comparison of the binding of glucose and glucose 1-phosphate derivatives to T-state glycogen phosphorylase b.
Biochemistry, 29, 1990
3GPB
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COMPARISON OF THE BINDING OF GLUCOSE AND GLUCOSE-1-PHOSPHATE DERIVATIVES TO T-STATE GLYCOGEN PHOSPHORYLASE B
Descriptor:GLYCOGEN PHOSPHORYLASE B, ALPHA-D-GLUCOSE-1-PHOSPHATE, PYRIDOXAL-5'-PHOSPHATE
Authors:Martin, J.L., Johnson, L.N.
Deposit date:1990-06-04
Release date:1992-10-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Comparison of the binding of glucose and glucose 1-phosphate derivatives to T-state glycogen phosphorylase b.
Biochemistry, 29, 1990
4GPB
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COMPARISON OF THE BINDING OF GLUCOSE AND GLUCOSE-1-PHOSPHATE DERIVATIVES TO T-STATE GLYCOGEN PHOSPHORYLASE B
Descriptor:GLYCOGEN PHOSPHORYLASE B, 2-DEOXY-2-FLUORO-ALPHA-D-GLUCOSE-1-PHOSPHATE, PYRIDOXAL-5'-PHOSPHATE
Authors:Martin, J.L., Johnson, L.N.
Deposit date:1990-06-04
Release date:1992-10-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Comparison of the binding of glucose and glucose 1-phosphate derivatives to T-state glycogen phosphorylase b.
Biochemistry, 29, 1990
5GPB
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COMPARISON OF THE BINDING OF GLUCOSE AND GLUCOSE-1-PHOSPHATE DERIVATIVES TO T-STATE GLYCOGEN PHOSPHORYLASE B
Descriptor:GLYCOGEN PHOSPHORYLASE B, GLUCOPYRANOSYL-1-METHYL-PHOSPHONIC ACID, ALPHA-D-GLUCOSE, ...
Authors:Martin, J.L., Johnson, L.N.
Deposit date:1990-06-04
Release date:1992-10-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Comparison of the binding of glucose and glucose 1-phosphate derivatives to T-state glycogen phosphorylase b.
Biochemistry, 29, 1990
7GPB
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STRUCTURAL MECHANISM FOR GLYCOGEN PHOSPHORYLASE CONTROL BY PHOSPHORYLATION AND AMP
Descriptor:GLYCOGEN PHOSPHORYLASE B, SULFATE ION, PYRIDOXAL-5'-PHOSPHATE, ...
Authors:Barford, D., Hu, S.-H., Johnson, L.N.
Deposit date:1990-11-13
Release date:1992-10-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural mechanism for glycogen phosphorylase control by phosphorylation and AMP.
J.Mol.Biol., 218, 1991
8GPB
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STRUCTURAL MECHANISM FOR GLYCOGEN PHOSPHORYLASE CONTROL BY PHOSPHORYLATION AND AMP
Descriptor:GLYCOGEN PHOSPHORYLASE B, PYRIDOXAL-5'-PHOSPHATE, ADENOSINE MONOPHOSPHATE
Authors:Barford, D., Hu, S.-H., Johnson, L.N.
Deposit date:1990-11-13
Release date:1992-10-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural mechanism for glycogen phosphorylase control by phosphorylation and AMP.
J.Mol.Biol., 218, 1991
9GPB
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THE ALLOSTERIC TRANSITION OF GLYCOGEN PHOSPHORYLASE
Descriptor:GLYCOGEN PHOSPHORYLASE B, SULFATE ION, PYRIDOXAL-5'-PHOSPHATE
Authors:Barford, D., Johnson, L.N.
Deposit date:1990-12-17
Release date:1992-10-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The allosteric transition of glycogen phosphorylase.
Nature, 340, 1989
1B4D
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AMIDOCARBAMATE INHIBITOR OF GLYCOGEN PHOSPHORYLASE
Descriptor:PROTEIN (GLYCOGEN PHOSPHORYLASE B), 1-DEOXY-1-METHOXYCARBAMIDO-BETA-D-GLUCO-2-HEPTULOPYRANOSONAMIDE, PYRIDOXAL-5'-PHOSPHATE, ...
Authors:Tsitsanou, K.E., Oikonomakos, N.G., Zographos, S.E., Skamnaki, V.T., Gregoriou, M., Watson, K.A., Johnson, L.N., Fleet, G.W.J.
Deposit date:1998-12-18
Release date:1998-12-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Effects of commonly used cryoprotectants on glycogen phosphorylase activity and structure.
Protein Sci., 8, 1999
2AMV
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THE STRUCTURE OF GLYCOGEN PHOSPHORYLASE B WITH AN ALKYL-DIHYDROPYRIDINE-DICARBOXYLIC ACID
Descriptor:PROTEIN (GLYCOGEN PHOSPHORYLASE), PYRIDOXAL-5'-PHOSPHATE, 2,3-DICARBOXY-4-(2-CHLORO-PHENYL)-1-ETHYL-5-ISOPROPOXYCARBONYL-6-METHYL-PYRIDINIUM, ...
Authors:Zographos, S.E., Oikonomakos, N.G., Johnson, L.N.
Deposit date:1998-10-13
Release date:1998-10-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The structure of glycogen phosphorylase b with an alkyldihydropyridine-dicarboxylic acid compound, a novel and potent inhibitor.
Structure, 5, 1997
1FS4
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STRUCTURES OF GLYCOGEN PHOSPHORYLASE-INHIBITOR COMPLEXES AND THE IMPLICATIONS FOR STRUCTURE-BASED DRUG DESIGN
Descriptor:GLYCOGEN PHOSPHORYLASE, 1-DEOXY-1-METHOXYCARBAMIDO-BETA-D-GLUCO-2-HEPTULOPYRANOSONAMIDE, PYRIDOXAL-5'-PHOSPHATE
Authors:Watson, K.A., Tsitsanou, K.E., Gregoriou, M., Zographos, S.E., Skamnaki, V.T., Oikonomakos, N.G., Fleet, G.W., Johnson, L.N.
Deposit date:2000-09-08
Release date:2000-10-04
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Kinetic and crystallographic studies of glucopyranose spirohydantoin and glucopyranosylamine analogs inhibitors of glycogen phosphorylase.
Proteins, 61, 2005
1FTQ
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STRUCTURES OF GLYCOGEN PHOSPHORYLASE-INHIBITOR COMPLEXES AND THE IMPLICATIONS FOR STRUCTURE-BASED DRUG DESIGN
Descriptor:GLYCOGEN PHOSPHORYLASE, 3-AMINO-8,9,10-TRIHYDROXY-7-HYDROXYMETHYL-6-OXA-1,3-DIAZA-SPIRO[4.5]DECANE-2,4-DIONE, PYRIDOXAL-5'-PHOSPHATE, ...
Authors:Watson, K.A., Tsitsanou, K.E., Gregoriou, M., Zographos, S.E., Skamnaki, V.T., Oikonomakos, N.G., Fleet, G.W., Johnson, L.N.
Deposit date:2000-09-13
Release date:2000-10-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Kinetic and crystallographic studies of glucopyranose spirohydantoin and glucopyranosylamine analogs inhibitors of glycogen phosphorylase.
Proteins, 61, 2005
1FTW
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STRUCTURES OF GLYCOGEN PHOSPHORYLASE-INHIBITOR COMPLEXES AND THE IMPLICATIONS FOR STRUCTURE-BASED DRUG DESIGN
Descriptor:GLYCOGEN PHOSPHORYLASE, 3,8,9,10-TETRAHYDROXY-7-HYDROXYMETHYL-6-OXA-1,3-DIAZA-SPIRO[4.5]DECANE-2,4-DIONE, PYRIDOXAL-5'-PHOSPHATE
Authors:Watson, K.A., Tsitsanou, K.E., Gregoriou, M., Zographos, S.E., Skamnaki, V.T., Oikonomakos, N.G., Fleet, G.W., Johnson, L.N.
Deposit date:2000-09-13
Release date:2000-10-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:Kinetic and crystallographic studies of glucopyranose spirohydantoin and glucopyranosylamine analogs inhibitors of glycogen phosphorylase.
Proteins, 61, 2005
1FTY
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STRUCTURES OF GLYCOGEN PHOSPHORYLASE-INHIBITOR COMPLEXES AND THE IMPLICATIONS FOR STRUCTURE-BASED DRUG DESIGN
Descriptor:GLYCOGEN PHOSPHORYLASE, 8,9,10-TRIHYDROXY-7-HYDROXYMETHYL-3-METHYL-6-OXA-1,3-DIAZA-SPIRO[4.5]DECANE-2,4-DIONE, PYRIDOXAL-5'-PHOSPHATE
Authors:Watson, K.A., Tsitsanou, K.E., Gregoriou, M., Zographos, S.E., Skamnaki, V.T., Oikonomakos, N.G., Fleet, G.W., Johnson, L.N.
Deposit date:2000-09-13
Release date:2000-10-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Kinetic and crystallographic studies of glucopyranose spirohydantoin and glucopyranosylamine analogs inhibitors of glycogen phosphorylase.
Proteins, 61, 2005
1FU4
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STRUCTURES OF GLYCOGEN PHOSPHORYLASE-INHIBITOR COMPLEXES AND THE IMPLICATIONS FOR STRUCTURE-BASED DRUG DESIGN
Descriptor:GLYCOGEN PHOSPHORYLASE, N-(8,9,10-TRIHYDROXY-7-HYDROXYMETHYL-2,4-DIOXO-6-OXA-1,3-DIAZA-SPIRO[4.5]DEC-3-YL-ACETAMIDE, PYRIDOXAL-5'-PHOSPHATE
Authors:Watson, K.A., Tsitsanou, K.E., Gregoriou, M., Zographos, S.E., Skamnaki, V.T., Oikonomakos, N.G., Fleet, G.W., Johnson, L.N.
Deposit date:2000-09-14
Release date:2000-10-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:Kinetic and crystallographic studies of glucopyranose spirohydantoin and glucopyranosylamine analogs inhibitors of glycogen phosphorylase.
Proteins, 61, 2005