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3H5V
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CRYSTAL STRUCTURE OF THE GLUR2-ATD
Descriptor:Glutamate receptor 2, N-ACETYL-D-GLUCOSAMINE
Authors:Jin, R., Singh, S.K., Gu, S., Furukawa, H., Sobolevsky, A., Zhou, J., Jin, Y., Gouaux, E.
Deposit date:2009-04-22
Release date:2009-06-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.33 Å)
Cite:Crystal structure and association behaviour of the GluR2 amino-terminal domain.
Embo J., 28, 2009
3H5W
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CRYSTAL STRUCTURE OF THE GLUR2-ATD IN SPACE GROUP P212121 WITHOUT SOLVENT
Descriptor:Glutamate receptor 2
Authors:Jin, R., Singh, S.K., Gu, S., Furukawa, H., Sobolevsky, A., Zhou, J., Jin, Y., Gouaux, E.
Deposit date:2009-04-22
Release date:2009-06-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.686 Å)
Cite:Crystal structure and association behaviour of the GluR2 amino-terminal domain.
Embo J., 28, 2009
1MXU
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CRYSTAL STRUCTURE OF THE GLUR2 LIGAND BINDING CORE (S1S2J) IN COMPLEX WITH BROMO-WILLARDIINE (CONTROL FOR THE CRYSTAL TITRATION EXPERIMENTS)
Descriptor:GLUTAMATE RECEPTOR 2, ZINC ION, 2-AMINO-3-(5-BROMO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID
Authors:Jin, R., Gouaux, E.
Deposit date:2002-10-03
Release date:2003-06-10
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Probing the Function, Conformational Plasticity, and Dimer-Dimer Contacts of the GluR2 Ligand-Binding Core: Studies of 5-Substituted Willardiines and GluR2 S1S2 in the Crystal
Biochemistry, 42, 2003
1MXV
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CRYSTAL TITRATION EXPERIMENTS (AMPA CO-CRYSTALS SOAKED IN 10 MM BRW)
Descriptor:GLUTAMATE RECEPTOR 2, ZINC ION
Authors:Jin, R., Gouaux, E.
Deposit date:2002-10-03
Release date:2003-06-10
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Probing the Function, Conformational Plasticity, and Dimer-Dimer Contacts of the GluR2 Ligand-Binding Core: Studies of 5-Substituted Willardiines and GluR2 S1S2 in the Crystal
Biochemistry, 42, 2003
1MXW
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CRYSTAL TITRATION EXPERIMENTS (AMPA CO-CRYSTALS SOAKED IN 1 MM BRW)
Descriptor:GLUTAMATE RECEPTOR 2, ZINC ION
Authors:Jin, R., Gouaux, E.
Deposit date:2002-10-03
Release date:2003-06-10
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Probing the function, conformational plasticity, and dimer-dimer contacts of the GluR2 ligand-binding core: studies of 5-substituted willardiines and GluR2 S1S2 in the crystal.
Biochemistry, 42, 2003
1MXX
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CRYSTAL TITRATION EXPERIMENTS (AMPA CO-CRYSTALS SOAKED IN 100 UM BRW)
Descriptor:GLUTAMATE RECEPTOR 2, ZINC ION
Authors:Jin, R., Gouaux, E.
Deposit date:2002-10-03
Release date:2003-06-10
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:Probing the Function, Conformational Plasticity, and Dimer-Dimer Contacts of the GluR2 Ligand-Binding Core: Studies of 5-Substituted Willardiines and GluR2 S1S2 in the Crystal
Biochemistry, 42, 2003
1MXY
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CRYSTAL TITRATION EXPERIMENTS (AMPA CO-CRYSTALS SOAKED IN 10 UM BRW)
Descriptor:GLUTAMATE RECEPTOR 2, ZINC ION
Authors:Jin, R., Gouaux, E.
Deposit date:2002-10-03
Release date:2003-06-10
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Probing the function, conformational plasticity, and dimer-dimer contacts of the GluR2 ligand-binding core: studies of 5-substituted willardiines and GluR2 S1S2 in the crystal.
Biochemistry, 42, 2003
1MXZ
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CRYSTAL TITRATION EXPERIMENTS (AMPA CO-CRYSTALS SOAKED IN 1 UM BRW)
Descriptor:GLUTAMATE RECEPTOR 2, ZINC ION
Authors:Jin, R., Gouaux, E.
Deposit date:2002-10-03
Release date:2003-06-10
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Probing the function, conformational plasticity, and dimer-dimer contacts of the GluR2 ligand-binding core: studies of 5-substituted willardiines and GluR2 S1S2 in the crystal.
Biochemistry, 42, 2003
1MY0
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CRYSTAL TITRATION EXPERIMENTS (AMPA CO-CRYSTALS SOAKED IN 100 NM BRW)
Descriptor:GLUTAMATE RECEPTOR 2, ZINC ION
Authors:Jin, R., Gouaux, E.
Deposit date:2002-10-03
Release date:2003-06-10
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Probing the Function, Conformational Plasticity, and Dimer-Dimer Contacts of the GluR2 Ligand-Binding Core: Studies of 5-Substituted Willardiines and GluR2 S1S2 in the Crystal
Biochemistry, 42, 2003
1MY1
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CRYSTAL TITRATION EXPERIMENTS (AMPA CO-CRYSTALS SOAKED IN 10 NM BRW)
Descriptor:GLUTAMATE RECEPTOR 2, ZINC ION
Authors:Jin, R., Gouaux, E.
Deposit date:2002-10-03
Release date:2003-06-10
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Probing the Function, Conformational Plasticity, and Dimer-Dimer Contacts of the GluR2 Ligand-Binding Core: Studies of 5-Substituted Willardiines and GluR2 S1S2 in the Crystal
Biochemistry, 42, 2003
1MY2
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CRYSTAL TITRATION EXPERIMENT (AMPA COMPLEX CONTROL)
Descriptor:GLUTAMATE RECEPTOR 2, ZINC ION, (S)-ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID
Authors:Jin, R., Gouaux, E.
Deposit date:2002-10-03
Release date:2003-06-10
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Probing the function, conformational plasticity, and dimer-dimer contacts of the GluR2 ligand-binding core: studies of 5-substituted willardiines and GluR2 S1S2 in the crystal.
Biochemistry, 42, 2003
1MY3
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CRYSTAL STRUCTURE OF GLUTAMATE RECEPTOR LIGAND-BINDING CORE IN COMPLEX WITH BROMO-WILLARDIINE IN THE ZN CRYSTAL FORM
Descriptor:GLUTAMATE RECEPTOR 2, ZINC ION, 2-AMINO-3-(5-BROMO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID
Authors:Jin, R., Gouaux, E.
Deposit date:2002-10-03
Release date:2003-06-10
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Probing the Function, Conformational Plasticity, and Dimer-Dimer Contacts of the GluR2 Ligand-Binding Core: Studies of 5-Substituted Willardiines and GluR2 S1S2 in the Crystal
Biochemistry, 42, 2003
1MY4
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CRYSTAL STRUCTURE OF GLUTAMATE RECEPTOR LIGAND-BINDING CORE IN COMPLEX WITH IODO-WILLARDIINE IN THE ZN CRYSTAL FORM
Descriptor:GLUTAMATE RECEPTOR 2, ZINC ION, 2-AMINO-3-(5-IODO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID
Authors:Jin, R., Gouaux, E.
Deposit date:2002-10-03
Release date:2003-06-10
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Probing the Function, Conformational Plasticity, and Dimer-Dimer Contacts of the GluR2 Ligand-Binding Core: Studies of 5-Substituted Willardiines and GluR2 S1S2 in the Crystal
Biochemistry, 42, 2003
2AL4
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CRYSTAL STRUCTURE OF THE GLUR2 LIGAND BINDING CORE (S1S2J) IN COMPLEX WITH QUISQUALATE AND CX614.
Descriptor:Glutamate receptor 2, ZINC ION, (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, ...
Authors:Jin, R., Clark, S., Weeks, A.M., Dudman, J.T., Gouaux, E., Partin, K.M.
Deposit date:2005-08-04
Release date:2005-10-25
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Mechanism of positive allosteric modulators acting on AMPA receptors.
J.Neurosci., 25, 2005
2AL5
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CRYSTAL STRUCTURE OF THE GLUR2 LIGAND BINDING CORE (S1S2J) IN COMPLEX WITH FLUORO-WILLARDIINE AND ANIRACETAM
Descriptor:Glutamate receptor 2, 2-AMINO-3-(5-FLUORO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID, 1-(4-METHOXYBENZOYL)-2-PYRROLIDINONE
Authors:Jin, R., Clark, S., Weeks, A.M., Dudman, J.T., Gouaux, E., Partin, K.M.
Deposit date:2005-08-04
Release date:2005-10-25
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Mechanism of positive allosteric modulators acting on AMPA receptors.
J.Neurosci., 25, 2005
1MM6
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CRYSTAL STRUCTURE OF THE GLUR2 LIGAND BINDING CORE (S1S2J) IN COMPLEX WITH QUISQUALATE IN A NON ZINC CRYSTAL FORM AT 2.15 ANGSTROMS RESOLUTION
Descriptor:GLUTAMATE RECEPTOR 2, SULFATE ION, (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, ...
Authors:Jin, R., Horning, M., Mayer, M.L., Gouaux, E.
Deposit date:2002-09-03
Release date:2003-02-04
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Mechanism of activation and selectivity in a ligand-gated ion channel: Structural and functional studies of GluR2 and quisqualate
Biochemistry, 41, 2002
1MM7
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CRYSTAL STRUCTURE OF THE GLUR2 LIGAND BINDING CORE (S1S2J) IN COMPLEX WITH QUISQUALATE IN A ZINC CRYSTAL FORM AT 1.65 ANGSTROMS RESOLUTION
Descriptor:GLUTAMATE RECEPTOR 2, ZINC ION, (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID
Authors:Jin, R., Horning, M., Mayer, M.L., Gouaux, E.
Deposit date:2002-09-03
Release date:2003-02-04
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Mechanism of Activation and Selectivity in a Ligand-Gated Ion Channel: Structural and Functional Studies of GluR2 and Quisqualate
Biochemistry, 41, 2003
1MQG
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CRYSTAL STRUCTURE OF THE GLUR2 LIGAND BINDING CORE (S1S2J) IN COMPLEX WITH IODO-WILLARDIINE AT 2.15 ANGSTROMS RESOLUTION
Descriptor:glutamate receptor 2, SULFATE ION, 2-AMINO-3-(5-IODO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID, ...
Authors:Jin, R., Banke, T.G., Mayer, M.L., Traynelis, S.F., Gouaux, E.
Deposit date:2002-09-16
Release date:2003-08-05
Last modified:2017-05-10
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural basis for partial agonist action at ionotropic glutamate receptors
Nat.Neurosci., 6, 2003
1MQH
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CRYSTAL STRUCTURE OF THE GLUR2 LIGAND BINDING CORE (S1S2J) IN COMPLEX WITH BROMO-WILLARDIINE AT 1.8 ANGSTROMS RESOLUTION
Descriptor:glutamate receptor 2, 2-AMINO-3-(5-BROMO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID
Authors:Jin, R., Banke, T.G., Mayer, M.L., Traynelis, S.F., Gouaux, E.
Deposit date:2002-09-16
Release date:2003-08-05
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis for partial agonist action at ionotropic glutamate receptors
Nat.Neurosci., 6, 2003
1MQI
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CRYSTAL STRUCTURE OF THE GLUR2 LIGAND BINDING CORE (S1S2J) IN COMPLEX WITH FLUORO-WILLARDIINE AT 1.35 ANGSTROMS RESOLUTION
Descriptor:glutamate receptor 2, 2-AMINO-3-(5-FLUORO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID
Authors:Jin, R., Banke, T.G., Mayer, M.L., Traynelis, S.F., Gouaux, E.
Deposit date:2002-09-16
Release date:2003-08-05
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Structural basis for partial agonist action at ionotropic glutamate receptors
Nat.Neurosci., 6, 2003
1MQJ
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CRYSTAL STRUCTURE OF THE GLUR2 LIGAND BINDING CORE (S1S2J) IN COMPLEX WITH WILLARDIINE AT 1.65 ANGSTROMS RESOLUTION
Descriptor:glutamate receptor 2, ZINC ION, 2-AMINO-3-(2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID
Authors:Jin, R., Banke, T.G., Mayer, M.L., Traynelis, S.F., Gouaux, E.
Deposit date:2002-09-16
Release date:2003-08-05
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structural basis for partial agonist action at ionotropic glutamate receptors
Nat.Neurosci., 6, 2003
1ZC3
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CRYSTAL STRUCTURE OF THE RAL-BINDING DOMAIN OF EXO84 IN COMPLEX WITH THE ACTIVE RALA
Descriptor:Ras-related protein Ral-A, exocyst complex protein Exo84, MAGNESIUM ION, ...
Authors:Jin, R., Junutula, J.R., Matern, H.T., Ervin, K.E., Scheller, R.H., Brunger, A.T.
Deposit date:2005-04-10
Release date:2005-06-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Exo84 and Sec5 are competitive regulatory Sec6/8 effectors to the RalA GTPase.
Embo J., 24, 2005
1ZC4
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CRYSTAL STRUCTURE OF THE RAL-BINDING DOMAIN OF EXO84 IN COMPLEX WITH THE ACTIVE RALA
Descriptor:Ras-related protein Ral-A, exocyst complex protein Exo84, MAGNESIUM ION, ...
Authors:Jin, R., Junutula, J.R., Matern, H.T., Ervin, K.E., Scheller, R.H., Brunger, A.T.
Deposit date:2005-04-10
Release date:2005-06-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Exo84 and Sec5 are competitive regulatory Sec6/8 effectors to the RalA GTPase.
Embo J., 24, 2005
2NM1
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STRUCTURE OF BONT/B IN COMPLEX WITH ITS PROTEIN RECEPTOR
Descriptor:Botulinum neurotoxin type B, Synaptotagmin-2
Authors:Jin, R., Rummel, A., Binz, T., Brunger, A.T.
Deposit date:2006-10-20
Release date:2006-12-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Botulinum neurotoxin B recognizes its protein receptor with high affinity and specificity.
Nature, 444, 2006
2QN0
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STRUCTURE OF BOTULINUM NEUROTOXIN SEROTYPE C1 LIGHT CHAIN PROTEASE
Descriptor:Neurotoxin, ZINC ION
Authors:Jin, R., Sikorra, S., Stegmann, C.M., Pich, A., Binz, T., Brunger, A.T.
Deposit date:2007-07-17
Release date:2007-09-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural and biochemical studies of botulinum neurotoxin serotype C1 light chain protease: implications for dual substrate specificity.
Biochemistry, 46, 2007