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CRYSTAL STRUCTURE OF THE FIRST BROMODOMAIN OF HUMAN BRD4 IN COMPLEX WITH 5-((4-FLUORO-1H-IMIDAZOL-1-YL)METHYL)QUINOLIN-8-OL
Descriptor:Bromodomain-containing protein 4, 5-[(4-fluoranylimidazol-1-yl)methyl]quinolin-8-ol
Authors:Xing, J., Zhang, R.K., Zheng, M.Y., Luo, C., Jiang, X.R.
Deposit date:2018-08-08
Release date:2018-12-12
Last modified:2018-12-26
Method:X-RAY DIFFRACTION (1.998 Å)
Cite:Rational design of 5-((1H-imidazol-1-yl)methyl)quinolin-8-ol derivatives as novel bromodomain-containing protein 4 inhibitors
Eur J Med Chem, 163, 2018