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4YWZ
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CRYSTAL STRUCTURE OF THE EXTRACELLULAR RECEPTOR DOMAIN OF THE ESSENTIAL SENSOR KINASE WALK FROM STAPHYLOCOCCUS AUREUS
Descriptor:Sensor protein kinase WalK
Authors:Ji, Q., Wawrzak, Z., He, C.
Deposit date:2015-03-21
Release date:2016-03-30
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure and mechanism of the essential two-component signal-transduction system WalKR in Staphylococcus aureus.
Nat Commun, 7, 2016
4HQM
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THE CRYSTAL STRUCTURE OF QSRR-MENADIONE COMPLEX
Descriptor:QsrR protein, 2-methylnaphthalene-1,4-diol
Authors:Ji, Q., Zhang, L., Jones, M.B., Sun, F., Deng, X., Liang, H., Brugarolas, P., Gao, N., Peterson, S.N., Lan, L., Bae, T., He, C.
Deposit date:2012-10-25
Release date:2013-03-06
Last modified:2013-05-22
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Molecular mechanism of quinone signaling mediated through S-quinonization of a YodB family repressor QsrR.
Proc.Natl.Acad.Sci.USA, 110, 2013
3T8R
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CRYSTAL STRUCTURE OF STAPHYLOCOCCUS AUREUS CYMR
Descriptor:Staphylococcus aureus CymR
Authors:He, C., Ji, Q.
Deposit date:2011-08-01
Release date:2012-05-16
Last modified:2012-07-18
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Staphylococcus aureus CymR Is a New Thiol-based Oxidation-sensing Regulator of Stress Resistance and Oxidative Response.
J.Biol.Chem., 287, 2012
3T8T
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CRYSTAL STRUCTURE OF STAPHYLOCOCCUS AUREUS CYMR OXIDIZED FORM
Descriptor:Staphylococcus aureus CymR (oxidized form)
Authors:He, C., Ji, Q.
Deposit date:2011-08-01
Release date:2012-05-16
Last modified:2012-07-18
Method:X-RAY DIFFRACTION (1.752 Å)
Cite:Staphylococcus aureus CymR Is a New Thiol-based Oxidation-sensing Regulator of Stress Resistance and Oxidative Response.
J.Biol.Chem., 287, 2012
4HQE
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THE CRYSTAL STRUCTURE OF QSRR-DNA COMPLEX
Descriptor:Transcriptional regulator QsrR, DNA (5'-D(*GP*GP*TP*AP*TP*AP*AP*TP*AP*AP*TP*TP*AP*TP*AP*CP*T)-3'), DNA (5'-D(*AP*GP*TP*AP*TP*AP*AP*TP*TP*AP*TP*TP*AP*TP*AP*CP*C)-3')
Authors:He, C., Ji, Q., Zhang, L.
Deposit date:2012-10-25
Release date:2013-03-06
Last modified:2013-05-22
Method:X-RAY DIFFRACTION (2.299 Å)
Cite:Molecular mechanism of quinone signaling mediated through S-quinonization of a YodB family repressor QsrR.
Proc.Natl.Acad.Sci.USA, 110, 2013
5YH8
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THE CRYSTAL STRUCTURE OF STAPHYLOCOCCUS AUREUS CNTA IN COMPLEX WITH STAPHYLOPINE AND NICKEL
Descriptor:Nickel ABC transporter substrate-binding protein, NICKEL (II) ION, (2~{S})-4-[[(2~{R})-3-(1~{H}-imidazol-4-yl)-1-oxidanyl-1-oxidanylidene-propan-2-yl]amino]-2-[[(2~{S})-1-oxidanyl-1-oxidanylidene-propan-2-yl]amino]butanoic acid, ...
Authors:Ji, Q., Song, L.
Deposit date:2017-09-27
Release date:2018-03-28
Last modified:2018-04-25
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:Mechanistic insights into staphylopine-mediated metal acquisition
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5YHG
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THE CRYSTAL STRUCTURE OF STAPHYLOCOCCUS AUREUS CNTA IN COMPLEX WITH STAPHYLOPINE AND ZINC
Descriptor:Nickel ABC transporter substrate-binding protein, ZINC ION, GLYCEROL, ...
Authors:Ji, Q., Song, L.
Deposit date:2017-09-28
Release date:2018-03-28
Last modified:2018-04-25
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Mechanistic insights into staphylopine-mediated metal acquisition
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
4GXO
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CRYSTAL STRUCTURE OF STAPHYLOCOCCUS AUREUS PROTEIN SARZ MUTANT C13E
Descriptor:MarR family regulatory protein, GLYCEROL
Authors:Sun, F., Ding, Y., Ji, Q., Liang, Z., Deng, X., Wong, C.C., Yi, C., Zhang, L., Xie, S., Alvarez, S., Hicks, L.M., Luo, C., Jiang, H., Lan, L., He, C.
Deposit date:2012-09-04
Release date:2012-09-26
Last modified:2012-10-03
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Protein cysteine phosphorylation of SarA/MgrA family transcriptional regulators mediates bacterial virulence and antibiotic resistance.
Proc.Natl.Acad.Sci.USA, 109, 2012
4ID7
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ACK1 KINASE IN COMPLEX WITH THE INHIBITOR CIS-3-[8-AMINO-1-(4-PHENOXYPHENYL)IMIDAZO[1,5-A]PYRAZIN-3-YL]CYCLOBUTANOL
Descriptor:Activated CDC42 kinase 1, cis-3-[8-amino-1-(4-phenoxyphenyl)imidazo[1,5-a]pyrazin-3-yl]cyclobutanol, SULFATE ION
Authors:Jin, M., Wang, J., Kleinberg, A., Kadalbajoo, M., Siu, K., Cooke, A., Bittner, M., Yao, Y., Thelemann, A., Ji, Q., Bhagwat, S., Crew, A.P., Pachter, J., Epstein, D., Mulvihill, M.J.
Deposit date:2012-12-11
Release date:2013-01-30
Last modified:2013-02-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Discovery of potent, selective and orally bioavailable imidazo[1,5-a]pyrazine derived ACK1 inhibitors.
Bioorg.Med.Chem.Lett., 23, 2013
5XS9
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CRYSTAL STRUCTURE OF MYCOBACTERIUM SMEGMATIS BIOQ
Descriptor:TetR family transcriptional regulator
Authors:Zhang, Y., Ji, Q., Feng, Y.
Deposit date:2017-06-13
Release date:2018-06-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural analysis of BioQ suggests a distinct regulatory mechanism for biotin, a nutritional virulence factor in Mycobacterium
To Be Published
5Y6I
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CRYSTAL STRUCTURE OF PSEUDOMONAS AERUGINOSA HMGR
Descriptor:Transcriptional regulator KdgR
Authors:Gu, T., Ji, Q., Liang, H.
Deposit date:2017-08-11
Release date:2018-08-15
Method:X-RAY DIFFRACTION (2.517 Å)
Cite:Crystal structure of Pseudomonas aeruginosa HmgR
To Be Published
5YH5
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THE CRYSTAL STRUCTURE OF STAPHYLOCOCCUS AUREUS CNTA IN APO FORM
Descriptor:Nickel ABC transporter substrate-binding protein, 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER
Authors:Song, L., Ji, Q.
Deposit date:2017-09-27
Release date:2018-03-28
Last modified:2018-04-25
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Mechanistic insights into staphylopine-mediated metal acquisition
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5YHE
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THE CRYSTAL STRUCTURE OF STAPHYLOCOCCUS AUREUS CNTA IN COMPLEX WITH STAPHYLOPINE AND COBALT
Descriptor:Nickel ABC transporter substrate-binding protein, CHLORIDE ION, ACETATE ION, ...
Authors:Song, L., Ji, Q.
Deposit date:2017-09-28
Release date:2018-03-28
Last modified:2018-04-25
Method:X-RAY DIFFRACTION (2.465 Å)
Cite:Mechanistic insights into staphylopine-mediated metal acquisition
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6JV3
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CRYSTAL STRUCTURE OF 5-HYDOXYLMETHYLCYTOSINE CONTAINING DECAMER DSDNA
Descriptor:DNA (5'-D(*CP*CP*AP*GP*(5HC)P*GP*CP*TP*GP*G)-3')
Authors:Zhang, L., Wang, Y.X.
Deposit date:2019-04-15
Release date:2019-07-31
Method:X-RAY DIFFRACTION (2.851 Å)
Cite:Thymine DNA glycosylase recognizes the geometry alteration of minor grooves induced by 5-formylcytosine and 5-carboxylcytosine
Chem Sci, 2019
6JV5
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CRYSTAL STRUCTURE OF 5-METHYLCYTOSINE CONTAINING DECAMER DSDNA
Descriptor:DNA (5'-D(*CP*CP*AP*GP*(5CM)P*GP*CP*TP*GP*G)-3')
Authors:Zhang, L., Wang, Y.X.
Deposit date:2019-04-15
Release date:2019-07-31
Method:X-RAY DIFFRACTION (1.401 Å)
Cite:Thymine DNA glycosylase recognizes the geometry alteration of minor grooves induced by 5-formylcytosine and 5-carboxylcytosine
Chem Sci, 2019
4NPL
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CRYSTAL STRUCTURE OF ZEBRAFISH ALKBH5 IN COMPLEX WITH ALPHA-KETOGLUTARATE
Descriptor:RNA demethylase ALKBH5, MANGANESE (II) ION, 2-OXOGLUTARIC ACID
Authors:He, C., Chen, W., Zhang, L.
Deposit date:2013-11-21
Release date:2014-02-19
Last modified:2014-04-02
Method:X-RAY DIFFRACTION (1.651 Å)
Cite:Crystal structure of the RNA demethylase ALKBH5 from zebrafish.
Febs Lett., 588, 2014
4NPM
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CRYSTAL STRUCTURE OF ZEBRAFISH ALKBH5 IN COMPLEX WITH SUCCINIC ACID
Descriptor:RNA demethylase ALKBH5, MANGANESE (II) ION, SUCCINIC ACID
Authors:He, C., Chen, W., Zhang, L.
Deposit date:2013-11-21
Release date:2014-02-19
Last modified:2014-04-02
Method:X-RAY DIFFRACTION (1.803 Å)
Cite:Crystal structure of the RNA demethylase ALKBH5 from zebrafish.
Febs Lett., 588, 2014
5EPO
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THE THREE-DIMENSIONAL STRUCTURE OF CLOSTRIDIUM ABSONUM 7ALPHA-HYDROXYSTEROID DEHYDROGENASE
Descriptor:7-alpha-hydroxysteroid deydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, TAUROCHENODEOXYCHOLIC ACID, ...
Authors:Lou, D., Wang, B., Wang, F.
Deposit date:2015-11-12
Release date:2016-03-23
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:The three-dimensional structure of Clostridium absonum 7 alpha-hydroxysteroid dehydrogenase: new insights into the conserved arginines for NADP(H) recognition
Sci Rep, 6, 2016