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5FU7
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BU of 5fu7 by Molmil
drosophila nanos NBR peptide bound to the NOT module of the human CCR4-NOT complex
Descriptor: CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1, CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 2, CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 3, ...
Authors:Raisch, T, Bhandari, D, Sabath, K, Helms, S, Valkov, E, Weichenrieder, O, Izaurralde, E.
Deposit date:2016-01-21
Release date:2016-03-23
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Distinct Modes of Recruitment of the Ccr4-not Complex by Drosophila and Vertebrate Nanos
Embo J., 35, 2016
5FU6
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BU of 5fu6 by Molmil
NOT module of the human CCR4-NOT complex (Crystallization mutant)
Descriptor: CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1, CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 2, CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 3
Authors:Raisch, T, Bhandari, D, Sabath, K, Helms, S, Valkov, E, Weichenrieder, O, Izaurralde, E.
Deposit date:2016-01-21
Release date:2016-03-23
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Distinct Modes of Recruitment of the Ccr4-not Complex by Drosophila and Vertebrate Nanos
Embo J., 35, 2016
5J3Q
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BU of 5j3q by Molmil
Crystal structure of S. pombe Dcp1:Edc1 mRNA decapping complex
Descriptor: Edc1, mRNA-decapping enzyme subunit 1
Authors:Valkov, E, Muthukumar, S, Chang, C.T, Jonas, S, Weichenrieder, O, Izaurralde, E.
Deposit date:2016-03-31
Release date:2016-05-18
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Structure of the Dcp2-Dcp1 mRNA-decapping complex in the activated conformation.
Nat.Struct.Mol.Biol., 23, 2016
1FT8
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BU of 1ft8 by Molmil
CRYSTAL STRUCTURE OF THE RNA-BINDING DOMAIN OF THE MRNA EXPORT FACTOR TAP
Descriptor: TIP ASSOCIATING PROTEIN
Authors:Liker, E, Fernandez, E, Izaurralde, E, Conti, E.
Deposit date:2000-09-12
Release date:2000-12-11
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:The structure of the mRNA export factor TAP reveals a cis arrangement of a non-canonical RNP domain and an LRR domain.
EMBO J., 19, 2000
5J3Y
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BU of 5j3y by Molmil
Crystal structure of S. pombe Dcp2:Dcp1 mRNA decapping complex
Descriptor: mRNA decapping complex subunit 2, mRNA-decapping enzyme subunit 1
Authors:Valkov, E, Muthukumar, S, Chang, C.T, Jonas, S, Weichenrieder, O, Izaurralde, E.
Deposit date:2016-03-31
Release date:2016-05-18
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.288 Å)
Cite:Structure of the Dcp2-Dcp1 mRNA-decapping complex in the activated conformation.
Nat.Struct.Mol.Biol., 23, 2016
5J3T
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BU of 5j3t by Molmil
Crystal structure of S. pombe Dcp2:Dcp1:Edc1 mRNA decapping complex
Descriptor: Edc1, FORMIC ACID, MAGNESIUM ION, ...
Authors:Valkov, E, Muthukumar, S, Chang, C.T, Jonas, S, Weichenrieder, O, Izaurralde, E.
Deposit date:2016-03-31
Release date:2016-05-18
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure of the Dcp2-Dcp1 mRNA-decapping complex in the activated conformation.
Nat.Struct.Mol.Biol., 23, 2016
1FO1
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BU of 1fo1 by Molmil
CRYSTAL STRUCTURE OF THE RNA-BINDING DOMAIN OF THE MRNA EXPORT FACTOR TAP
Descriptor: NUCLEAR RNA EXPORT FACTOR 1
Authors:Liker, E, Fernandez, E, Izaurralde, E, Conti, E.
Deposit date:2000-08-24
Release date:2000-11-03
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The structure of the mRNA export factor TAP reveals a cis arrangement of a non-canonical RNP domain and an LRR domain.
EMBO J., 19, 2000
4GMJ
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BU of 4gmj by Molmil
Structure of human NOT1 MIF4G domain co-crystallized with CAF1
Descriptor: CCR4-NOT transcription complex subunit 1, CCR4-NOT transcription complex subunit 7, CHLORIDE ION, ...
Authors:Petit, P, Weichenrieder, O, Wohlbold, L, Izaurralde, E.
Deposit date:2012-08-16
Release date:2012-10-03
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The structural basis for the interaction between the CAF1 nuclease and the NOT1 scaffold of the human CCR4-NOT deadenylase complex
Nucleic Acids Res., 40, 2012
4GML
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BU of 4gml by Molmil
Crystal structure of human NOT1 MIF4G domain
Descriptor: CCR4-NOT transcription complex subunit 1
Authors:Petit, P, Weichenrieder, O, Wohlbold, L, Izaurralde, E.
Deposit date:2012-08-16
Release date:2012-10-03
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The structural basis for the interaction between the CAF1 nuclease and the NOT1 scaffold of the human CCR4-NOT deadenylase complex
Nucleic Acids Res., 40, 2012
2B9Z
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BU of 2b9z by Molmil
Solution structure of FHV B2, a viral suppressor of RNAi
Descriptor: B2 protein
Authors:Lingel, A, Simon, B, Izaurralde, E, Sattler, M.
Deposit date:2005-10-13
Release date:2005-11-29
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:The structure of the flock house virus B2 protein, a viral suppressor of RNA interference, shows a novel mode of double-stranded RNA recognition.
Embo Rep., 6, 2005
3ZHE
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BU of 3zhe by Molmil
Structure of the C. elegans SMG5-SMG7 complex
Descriptor: NONSENSE-MEDIATED MRNA DECAY PROTEIN, PROTEIN SMG-7
Authors:Jonas, S, Weichenrieder, O, Izaurralde, E.
Deposit date:2012-12-21
Release date:2013-02-06
Method:X-RAY DIFFRACTION (3 Å)
Cite:An Unusual Arrangement of Two 14-3-3-Like Domains in the Smg5-Smg7 Heterodimer is Required for Efficient Nonsense-Mediated Mrna Decay.
Genes Dev., 27, 2013
6HOM
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BU of 6hom by Molmil
Drosophila NOT4 CBM peptide bound to human CAF40
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CCR4-NOT transcription complex subunit 4, isoform L, ...
Authors:Raisch, T, Izaurralde, E, Weichenrieder, O.
Deposit date:2018-09-17
Release date:2019-02-06
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A conserved CAF40-binding motif in metazoan NOT4 mediates association with the CCR4-NOT complex.
Genes Dev., 33, 2019
6HON
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BU of 6hon by Molmil
Drosophila NOT4 CBM peptide bound to human CAF40
Descriptor: CCR4-NOT transcription complex subunit 4, isoform L, CCR4-NOT transcription complex subunit 9, ...
Authors:Raisch, T, Izaurralde, E, Weichenrieder, O.
Deposit date:2018-09-17
Release date:2019-02-06
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A conserved CAF40-binding motif in metazoan NOT4 mediates association with the CCR4-NOT complex.
Genes Dev., 33, 2019
1HL6
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BU of 1hl6 by Molmil
A novel mode of RBD-protein recognition in the Y14-mago complex
Descriptor: CG8781 PROTEIN, MAGO NASHI PROTEIN
Authors:Fribourg, S, Gatfield, D, Yao, W, Izaurralde, E, Conti, E.
Deposit date:2003-03-13
Release date:2003-05-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A Novel Mode of Rbd-Protein Recognition in the Y14-Mago Complex
Nat.Struct.Biol., 10, 2003
1T2S
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BU of 1t2s by Molmil
Structural basis for 3' end recognition of nucleic acids by the Drosophila Argonaute 2 PAZ domain
Descriptor: 5'-D(*CP*TP*CP*AP*C)-3', Argonaute 2
Authors:Lingel, A, Simon, B, Izaurralde, E, Sattler, M.
Deposit date:2004-04-22
Release date:2004-06-01
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Nucleic acid 3'-end recognition by the Argonaute2 PAZ domain.
Nat.Struct.Mol.Biol., 11, 2004
1T2R
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BU of 1t2r by Molmil
Structural basis for 3' end recognition of nucleic acids by the Drosophila Argonaute 2 PAZ domain
Descriptor: 5'-R(*CP*UP*CP*AP*C)-3', Argonaute 2
Authors:Lingel, A, Simon, B, Izaurralde, E, Sattler, M.
Deposit date:2004-04-22
Release date:2004-06-01
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Nucleic acid 3'-end recognition by the Argonaute2 PAZ domain.
Nat.Struct.Mol.Biol., 11, 2004
1W3B
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BU of 1w3b by Molmil
The superhelical TPR domain of O-linked GlcNAc transferase reveals structural similarities to importin alpha.
Descriptor: CALCIUM ION, UDP-N-ACETYLGLUCOSAMINE--PEPTIDE N-ACETYLGLUCOSAMINYLTRANSFERASE 110
Authors:Jinek, M, Rehwinkel, J, Lazarus, B.D, Izaurralde, E, Hanover, J.A, Conti, E.
Deposit date:2004-07-14
Release date:2004-09-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:The Superhelical Tpr-Repeat Domain of O-Linked Glcnac Transferase Exhibits Structural Similarities to Importin Alpha
Nat.Struct.Mol.Biol., 11, 2004
1RK8
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BU of 1rk8 by Molmil
Structure of the cytosolic protein PYM bound to the Mago-Y14 core of the exon junction complex
Descriptor: CALCIUM ION, CG8781-PA protein, Mago nashi protein, ...
Authors:Bono, F, Ebert, J, Guettler, T, Izaurralde, E, Conti, E.
Deposit date:2003-11-21
Release date:2004-04-13
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Molecular insights into the interaction of PYM with the Mago-Y14 core of the exon junction complex
EMBO Rep., 5, 2004
1YA0
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BU of 1ya0 by Molmil
Crystal structure of the N-terminal domain of human SMG7
Descriptor: SMG-7 transcript variant 2, SULFATE ION
Authors:Fukuhara, N, Ebert, J, Unterholzner, L, Lindner, D, Izaurralde, E, Conti, E.
Deposit date:2004-12-17
Release date:2005-03-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:SMG7 Is a 14-3-3-like Adaptor in the Nonsense-Mediated mRNA Decay Pathway.
Mol.Cell, 17, 2005
3RW6
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BU of 3rw6 by Molmil
Structure of nuclear RNA export factor TAP bound to CTE RNA
Descriptor: Nuclear RNA export factor 1, constitutive transport element(CTE)of Mason-Pfizer monkey virus RNA
Authors:Teplova, M, Khin, N.W, Patel, D.J, Izaurralde, E.
Deposit date:2011-05-07
Release date:2011-08-10
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure-function studies of nucleocytoplasmic transport of retroviral genomic RNA by mRNA export factor TAP.
Nat.Struct.Mol.Biol., 18, 2011
3RW7
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BU of 3rw7 by Molmil
Structure of N-terminal domain of nuclear RNA export factor TAP
Descriptor: Nuclear RNA export factor 1
Authors:Teplova, M, Khin, N.W, Wohlbold, L, Izaurralde, E, Patel, D.J.
Deposit date:2011-05-07
Release date:2011-08-10
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure-function studies of nucleocytoplasmic transport of retroviral genomic RNA by mRNA export factor TAP.
Nat.Struct.Mol.Biol., 18, 2011
1JKG
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BU of 1jkg by Molmil
Structural basis for the recognition of a nucleoporin FG-repeat by the NTF2-like domain of TAP-p15 mRNA nuclear export factor
Descriptor: TAP, p15
Authors:Fribourg, S, Braun, I.C, Izaurralde, E, Conti, E.
Deposit date:2001-07-12
Release date:2001-10-17
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for the recognition of a nucleoporin FG repeat by the NTF2-like domain of the TAP/p15 mRNA nuclear export factor.
Mol.Cell, 8, 2001
1JN5
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BU of 1jn5 by Molmil
Structural basis for the recognition of a nucleoporin FG-repeat by the NTF2-like domain of TAP-p15 mRNA export factor
Descriptor: FG-repeat, TAP, p15
Authors:Fribourg, S, Braun, I.C, Izaurralde, E, Conti, E.
Deposit date:2001-07-23
Release date:2001-10-17
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for the recognition of a nucleoporin FG repeat by the NTF2-like domain of the TAP/p15 mRNA nuclear export factor.
Mol.Cell, 8, 2001
2HWX
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BU of 2hwx by Molmil
Structure of human SMG6 E1282C PIN domain mutant.
Descriptor: Telomerase-binding protein EST1A
Authors:Glavan, F, Behm-Ansmant, I, Izaurralde, E, Conti, E.
Deposit date:2006-08-02
Release date:2006-11-14
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structures of the PIN domains of SMG6 and SMG5 reveal a nuclease within the mRNA surveillance complex.
Embo J., 25, 2006
2HWW
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BU of 2hww by Molmil
Structure of PIN domain of human SMG6
Descriptor: Telomerase-binding protein EST1A
Authors:Glavan, F, Behm-Ansmant, I, Izaurralde, E, Conti, E.
Deposit date:2006-08-02
Release date:2006-11-14
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structures of the PIN domains of SMG6 and SMG5 reveal a nuclease within the mRNA surveillance complex.
Embo J., 25, 2006

 

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