Author results

2LM3
  • Download 2lm3
  • View 2lm3
Molmil generated image of 2lm3
STRUCTURE OF THE RHESUS MONKEY TRIM5ALPHA PRYSPRY DOMAIN
Descriptor:Tripartite motif-containing protein 5
Authors:Biris, N., Yang, Y., Taylor, A.B., Tomashevski, A., Guo, M., Hart, P.J., Diaz-Griffero, F., Ivanov, D.N.
Deposit date:2011-11-21
Release date:2012-08-08
Last modified:2013-06-19
Method:SOLUTION NMR
Cite:Structure of the rhesus monkey TRIM5alpha PRYSPRY domain, the HIV capsid recognition module.
Proc.Natl.Acad.Sci.USA, 109, 2012
4TKP
  • Download 4tkp
  • View 4tkp
Molmil generated image of 4tkp
COMPLEX OF UBC13 WITH THE RING DOMAIN OF THE TRIM5ALPHA RETROVIRAL RESTRICTION FACTOR
Descriptor:Ubiquitin-conjugating enzyme E2 N, Tripartite motif-containing protein 5, SULFATE ION, ...
Authors:Johnson, R., Taylor, A.B., Hart, P.J., Ivanov, D.N.
Deposit date:2014-05-27
Release date:2015-07-22
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Activation of the Ubc13-Ub adduct by the RING domain of the TRIM5alpha retroviral restriction factor offers insight into the mechanism of molecular pattern recognition by TRIM proteins
Cell Rep, 2015
4WYM
  • Download 4wym
  • View 4wym
Molmil generated image of 4wym
STRUCTURAL BASIS OF HIV-1 CAPSID RECOGNITION BY CPSF6
Descriptor:Capsid protein p24, ISOFORM 2 OF CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 6
Authors:Battacharya, A., Taylor, A.B., Hart, P.J., Ivanov, D.N.
Deposit date:2014-11-17
Release date:2014-12-17
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis of HIV-1 capsid recognition by PF74 and CPSF6.
Proc.Natl.Acad.Sci.USA, 111, 2014
3UV9
  • Download 3uv9
  • View 3uv9
Molmil generated image of 3uv9
STRUCTURE OF THE RHESUS MONKEY TRIM5ALPHA DELTAV1 PRYSPRY DOMAIN
Descriptor:Tripartite motif-containing protein 5
Authors:Biris, N., Yang, Y., Taylor, A.B., Tomashevskii, A., Guo, M., Hart, P.J., Diaz-Griffero, F., Ivanov, D.
Deposit date:2011-11-29
Release date:2012-08-08
Last modified:2017-08-16
Method:X-RAY DIFFRACTION (1.549 Å)
Cite:Structure of the rhesus monkey TRIM5alpha PRYSPRY domain, the HIV capsid recognition module.
Proc.Natl.Acad.Sci.USA, 109, 2012
4QNB
  • Download 4qnb
  • View 4qnb
Molmil generated image of 4qnb
DISULFIDE STABILIZED HIV-1 CA HEXAMER IN COMPLEX WITH PHENYL-L-PHENYLALANINAMIDE INHIBITOR
Descriptor:CAPSID PROTEIN P24, N-METHYL-NALPHA-[(2-METHYL-1H-INDOL-3-YL)ACETYL]-N-PHENYL-L-PHENYLALANINAMIDE
Authors:Pornillos, O.
Deposit date:2014-06-17
Release date:2014-12-31
Last modified:2015-02-25
Method:X-RAY DIFFRACTION (1.996 Å)
Cite:Structural basis of HIV-1 capsid recognition by PF74 and CPSF6.
Proc.Natl.Acad.Sci.USA, 111, 2014
5JVT
  • Download 5jvt
  • View 5jvt
Molmil generated image of 5jvt
CRYSTAL STRUCTURE OF THE DNA BINDING DOMAIN OF TRANSCRIPTION FACTOR FLI1 IN COMPLEX WITH AN 11-MER DNA GACCGGAAGTG
Descriptor:Friend leukemia integration 1 transcription factor, DNA (5'-D(*GP*AP*CP*CP*GP*GP*AP*AP*GP*TP*G)-3'), DNA (5'-D(*CP*AP*CP*TP*TP*CP*CP*GP*GP*TP*C)-3'), ...
Authors:Hou, C., Tsodikov, O.V.
Deposit date:2016-05-11
Release date:2016-09-14
Last modified:2016-10-26
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structures of mithramycin analogues bound to DNA and implications for targeting transcription factor FLI1.
Nucleic Acids Res., 44, 2016
5JVW
  • Download 5jvw
  • View 5jvw
Molmil generated image of 5jvw
CRYSTAL STRUCTURE OF MITHRAMYCIN ANALOGUE MTM SA-TRP IN COMPLEX WITH A 10-MER DNA AGAGGCCTCT.
Descriptor:DNA (5'-D(*AP*GP*AP*GP*GP*CP*CP*TP*CP*T)-3'), ZINC ION, SODIUM ION, ...
Authors:Hou, C., Rohr, J., Tsodikov, O.V.
Deposit date:2016-05-11
Release date:2016-09-14
Last modified:2016-10-26
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of mithramycin analogues bound to DNA and implications for targeting transcription factor FLI1.
Nucleic Acids Res., 44, 2016
5JW0
  • Download 5jw0
  • View 5jw0
Molmil generated image of 5jw0
CRYSTAL STRUCTURE OF MITHRAMYCIN ANALOGUE MTM SA-PHE IN COMPLEX WITH A 10-MER DNA AGGGTACCCT
Descriptor:DNA (5'-D(P*AP*GP*GP*GP*TP*AP*CP*CP*CP*T)-3'), Plicamycin, mithramycin analogue MTM SA-Phe, ...
Authors:Hou, C., Rohr, J., Tsodikov, O.V.
Deposit date:2016-05-11
Release date:2016-09-14
Last modified:2016-10-26
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structures of mithramycin analogues bound to DNA and implications for targeting transcription factor FLI1.
Nucleic Acids Res., 44, 2016
5JW2
  • Download 5jw2
  • View 5jw2
Molmil generated image of 5jw2
CRYSTAL STRUCTURE OF MITHRAMYCIN ANALOGUE MTM SA-PHE IN COMPLEX WITH A 10-MER DNA AGGGATCCCT
Descriptor:DNA (5'-D(*AP*GP*GP*GP*AP*TP*CP*CP*CP*T)-3'), Plicamycin, mithramycin analogue MTM SA-Phe, ...
Authors:Hou, C., Rohr, J., Tsodikov, O.V.
Deposit date:2016-05-11
Release date:2016-09-14
Last modified:2016-10-26
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structures of mithramycin analogues bound to DNA and implications for targeting transcription factor FLI1.
Nucleic Acids Res., 44, 2016
5VA4
  • Download 5va4
  • View 5va4
Molmil generated image of 5va4
TRIM-CYCLOPHILIN A B-BOX 2 AND COILED-COIL CHIMERA
Descriptor:TRIM5/cyclophilin A V4 fusion protein, ZINC ION
Authors:Wagner, J.M., Ganser-Pornillos, B.K., Pornillos, O.W.
Deposit date:2017-03-24
Release date:2017-11-22
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (2.306 Å)
Cite:General Model for Retroviral Capsid Pattern Recognition by TRIM5 Proteins.
J. Virol., 92, 2018
6OVQ
  • Download 6ovq
  • View 6ovq
Molmil generated image of 6ovq
CRYSTAL STRUCTURE OF MITHRAMYCIN 3-SIDE CHAIN KETO-REDUCTASE MTMW
Descriptor:Putative Side chain reductase, GLYCEROL
Authors:Hou, C., Yu, X., Rohr, J., Tsodikov, O.V.
Deposit date:2019-05-08
Release date:2019-11-27
Last modified:2020-01-15
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Discovery of a Cryptic Intermediate in Late Steps of Mithramycin Biosynthesis.
Angew.Chem.Int.Ed.Engl., 59, 2020
6OVX
  • Download 6ovx
  • View 6ovx
Molmil generated image of 6ovx
CRYSTAL STRUCTURE OF MITHRAMYCIN 3-SIDE CHAIN KETO-REDUCTASE MTMW IN COMPLEX WITH NAD+, P422 FORM
Descriptor:Putative side chain reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, GLYCEROL
Authors:Hou, C., Yu, X., Rohr, J., Tsodikov, O.V.
Deposit date:2019-05-08
Release date:2019-11-27
Last modified:2020-01-15
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Discovery of a Cryptic Intermediate in Late Steps of Mithramycin Biosynthesis.
Angew.Chem.Int.Ed.Engl., 59, 2020
6OW0
  • Download 6ow0
  • View 6ow0
Molmil generated image of 6ow0
CRYSTAL STRUCTURE OF MITHRAMYCIN 3-SIDE CHAIN KETO-REDUCTASE MTMW IN COMPLEX WITH NAD+ AND PEG
Descriptor:MtmW, DI(HYDROXYETHYL)ETHER, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Hou, C., Yu, X., Rohr, J., Tsodikov, O.V.
Deposit date:2019-05-08
Release date:2019-11-27
Last modified:2020-01-15
Method:X-RAY DIFFRACTION (2.67 Å)
Cite:Discovery of a Cryptic Intermediate in Late Steps of Mithramycin Biosynthesis.
Angew.Chem.Int.Ed.Engl., 59, 2020