Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
8IG0
DownloadVisualize
BU of 8ig0 by Molmil
Crystal structure of menin in complex with DS-1594b
Descriptor: (1R,2S,4R)-4-[[4-(5,6-dimethoxypyridazin-3-yl)phenyl]methylamino]-2-[methyl-[6-[2,2,2-tris(fluoranyl)ethyl]thieno[2,3-d]pyrimidin-4-yl]amino]cyclopentan-1-ol, DIMETHYL SULFOXIDE, Menin, ...
Authors:Suzuki, M, Yoneyama, T, Imai, E.
Deposit date:2023-02-20
Release date:2023-03-22
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A novel Menin-MLL1 inhibitor, DS-1594a, prevents the progression of acute leukemia with rearranged MLL1 or mutated NPM1.
Cancer Cell Int, 23, 2023
6J6Y
DownloadVisualize
BU of 6j6y by Molmil
FGFR4 D2 - Fab complex
Descriptor: Fab Heavy chain, Fab light chain, Fibroblast growth factor receptor 4
Authors:Takahashi, M, Hanzawa, H.
Deposit date:2019-01-16
Release date:2019-08-07
Last modified:2019-10-16
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Preclinical Development of U3-1784, a Novel FGFR4 Antibody Against Cancer, and Avoidance of Its On-target Toxicity.
Mol.Cancer Ther., 18, 2019
3Q3K
DownloadVisualize
BU of 3q3k by Molmil
Factor Xa in complex with a phenylenediamine derivative
Descriptor: Activated factor Xa heavy chain, CALCIUM ION, Factor X light chain, ...
Authors:Suzuki, M, Imai, E.
Deposit date:2010-12-22
Release date:2011-12-28
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Design, synthesis and SAR of novel ethylenediamine and phenylenediamine derivatives as factor Xa inhibitors.
Bioorg.Med.Chem.Lett., 21, 2011

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon