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2N80
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BU of 2n80 by Molmil
p75NTR DD:RhoGDI
Descriptor: Rho GDP-dissociation inhibitor 1, Tumor necrosis factor receptor superfamily member 16
Authors:Lin, Z, Ibanez, C.F.
Deposit date:2015-09-30
Release date:2015-12-23
Method:SOLUTION NMR
Cite:Structural basis of death domain signaling in the p75 neurotrophin receptor
Elife, 4, 2015
2N97
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BU of 2n97 by Molmil
DD homodimer
Descriptor: Tumor necrosis factor receptor superfamily member 16
Authors:Lin, Z, Ibanez, C.F.
Deposit date:2015-11-07
Release date:2015-12-23
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural basis of death domain signaling in the p75 neurotrophin receptor
Elife, 4, 2015
2N7Z
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BU of 2n7z by Molmil
Solution structure of RIP2 CARD
Descriptor: Receptor-interacting serine/threonine-protein kinase 2
Authors:Lin, Z, Ibanez, C.F.
Deposit date:2015-09-28
Release date:2015-12-23
Last modified:2016-01-13
Method:SOLUTION NMR
Cite:Structural basis of death domain signaling in the p75 neurotrophin receptor
Elife, 4, 2015
2N83
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BU of 2n83 by Molmil
p75NTR DD:RIP2 CARD
Descriptor: Receptor-interacting serine/threonine-protein kinase 2, Tumor necrosis factor receptor superfamily member 16
Authors:Lin, Z, Ibanez, C.F.
Deposit date:2015-10-02
Release date:2015-12-23
Last modified:2016-04-27
Method:SOLUTION NMR
Cite:Structural basis of death domain signaling in the p75 neurotrophin receptor
Elife, 4, 2015
5ZGG
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BU of 5zgg by Molmil
NMR structure of p75NTR transmembrane domain in complex with NSC49652
Descriptor: (2E)-1-(2-hydroxyphenyl)-3-(pyridin-3-yl)prop-2-en-1-one, Tumor necrosis factor receptor superfamily member 16
Authors:Lin, Z, Ibanez, C.
Deposit date:2018-03-08
Release date:2019-03-13
Last modified:2019-09-25
Method:SOLUTION NMR
Cite:A Small Molecule Targeting the Transmembrane Domain of Death Receptor p75NTRInduces Melanoma Cell Death and Reduces Tumor Growth.
Cell Chem Biol, 25, 2018
8X8T
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BU of 8x8t by Molmil
NMR structure of p75NTR juxtamembrane domain in complex with RhoGDI N-terminal domain containing a phosphorylation-mimicking S34D mutation
Descriptor: Rho GDP-dissociation inhibitor 1, Tumor necrosis factor receptor superfamily member 16
Authors:Lin, Z, Li, Z.
Deposit date:2023-11-28
Release date:2024-04-03
Method:SOLUTION NMR
Cite:RhoGDI phosphorylation by PKC promotes its interaction with death receptor p75 NTR to gate axon growth and neuron survival.
Embo Rep., 25, 2024
7CSQ
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BU of 7csq by Molmil
Solution structure of the complex between p75NTR-DD and TRADD-DD
Descriptor: Tumor necrosis factor receptor superfamily member 16, Tumor necrosis factor receptor type 1-associated DEATH domain protein
Authors:Lin, Z, Zhang, N.
Deposit date:2020-08-16
Release date:2021-08-25
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Structural basis of NF-kappa B signaling by the p75 neurotrophin receptor interaction with adaptor protein TRADD through their respective death domains.
J.Biol.Chem., 297, 2021
1NGR
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BU of 1ngr by Molmil
DEATH DOMAIN OF P75 LOW AFFINITY NEUROTROPHIN RECEPTOR, RESIDUES 334-418, NMR, 20 STRUCTURES
Descriptor: P75 LOW AFFINITY NEUROTROPHIN RECEPTOR
Authors:Otting, G, Liepinsh, E.
Deposit date:1997-01-28
Release date:1997-07-29
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:NMR structure of the death domain of the p75 neurotrophin receptor.
EMBO J., 16, 1997
2IVS
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BU of 2ivs by Molmil
Crystal structure of non-phosphorylated RET tyrosine kinase domain
Descriptor: 2',3'- cyclic AMP, FORMIC ACID, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE RECEPTOR RET
Authors:Knowles, P.P, Murray-Rust, J, McDonald, N.Q.
Deposit date:2006-06-16
Release date:2006-08-14
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure and Chemical Inhibition of the Ret Tyrosine Kinase Domain.
J.Biol.Chem., 281, 2006
2IVT
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BU of 2ivt by Molmil
Crystal structure of phosphorylated RET tyrosine kinase domain
Descriptor: ADENOSINE MONOPHOSPHATE, FORMIC ACID, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE RECEPTOR RET PRECURSOR
Authors:Knowles, P.P, Murray-Rust, J, McDonald, N.Q.
Deposit date:2006-06-16
Release date:2006-08-14
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure and chemical inhibition of the RET tyrosine kinase domain.
J. Biol. Chem., 281, 2006
2IVV
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BU of 2ivv by Molmil
Crystal structure of phosphorylated RET tyrosine kinase domain complexed with the inhibitor PP1
Descriptor: 1-TER-BUTYL-3-P-TOLYL-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-YLAMINE, FORMIC ACID, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE RECEPTOR RET PRECURSOR
Authors:Knowles, P.P, Murray-Rust, J, McDonald, N.Q.
Deposit date:2006-06-16
Release date:2006-08-14
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structure and chemical inhibition of the RET tyrosine kinase domain.
J. Biol. Chem., 281, 2006
2IVU
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BU of 2ivu by Molmil
Crystal structure of phosphorylated RET tyrosine kinase domain complexed with the inhibitor ZD6474
Descriptor: FORMIC ACID, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE RECEPTOR RET PRECURSOR, Vandetanib
Authors:Knowles, P.P, Murray-Rust, J, McDonald, N.Q.
Deposit date:2006-06-16
Release date:2006-08-10
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure and chemical inhibition of the RET tyrosine kinase domain.
J. Biol. Chem., 281, 2006

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