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5ICD
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REGULATION OF AN ENZYME BY PHOSPHORYLATION AT THE ACTIVE SITE
Descriptor:ISOCITRATE DEHYDROGENASE, MAGNESIUM ION, ISOCITRIC ACID
Authors:Hurley, J.H., Dean, A.M., Sohl, J.L., Koshlandjunior, D.E., Stroud, R.M.
Deposit date:1990-05-30
Release date:1991-10-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Regulation of an enzyme by phosphorylation at the active site.
Science, 249, 1990
9ICD
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CATALYTIC MECHANISM OF NADP+-DEPENDENT ISOCITRATE DEHYDROGENASE: IMPLICATIONS FROM THE STRUCTURES OF MAGNESIUM-ISOCITRATE AND NADP+ COMPLEXES
Descriptor:ISOCITRATE DEHYDROGENASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Hurley, J.H., Dean, A.M., Koshland Jr., D.E., Stroud, R.M.
Deposit date:1991-07-29
Release date:1991-10-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Catalytic mechanism of NADP(+)-dependent isocitrate dehydrogenase: implications from the structures of magnesium-isocitrate and NADP+ complexes.
Biochemistry, 30, 1991
6ICD
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REGULATION OF AN ENZYME BY PHOSPHORYLATION AT THE ACTIVE SITE
Descriptor:ISOCITRATE DEHYDROGENASE
Authors:Hurley, J.H., Dean, A.M., Sohl, J.L., Koshlandjunior, D.E., Stroud, R.M.
Deposit date:1990-05-30
Release date:1991-10-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Regulation of an enzyme by phosphorylation at the active site.
Science, 249, 1990
7ICD
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REGULATION OF AN ENZYME BY PHOSPHORYLATION AT THE ACTIVE SITE
Descriptor:ISOCITRATE DEHYDROGENASE
Authors:Hurley, J.H., Dean, A.M., Sohl, J.L., Koshlandjunior, D.E., Stroud, R.M.
Deposit date:1990-05-30
Release date:1991-10-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Regulation of an enzyme by phosphorylation at the active site.
Science, 249, 1990
8ICD
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REGULATION OF AN ENZYME BY PHOSPHORYLATION AT THE ACTIVE SITE
Descriptor:ISOCITRATE DEHYDROGENASE, MAGNESIUM ION, ISOCITRIC ACID
Authors:Hurley, J.H., Dean, A.M., Sohl, J.L., Koshlandjunior, D.E., Stroud, R.M.
Deposit date:1990-05-30
Release date:1991-10-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Regulation of an enzyme by phosphorylation at the active site.
Science, 249, 1990
3ICD
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STRUCTURE OF A BACTERIAL ENZYME REGULATED BY PHOSPHORYLATION, ISOCITRATE DEHYDROGENASE
Descriptor:ISOCITRATE DEHYDROGENASE
Authors:Hurley, J.H., Thorsness, P.E., Ramalingam, V., Helmers, N.H., Koshlandjunior, D.E., Stroud, R.M.
Deposit date:1989-12-28
Release date:1991-01-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of a bacterial enzyme regulated by phosphorylation, isocitrate dehydrogenase.
Proc.Natl.Acad.Sci.USA, 86, 1989
4ICD
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REGULATION OF ISOCITRATE DEHYDROGENASE BY PHOSPHORYLATION INVOLVES NO LONG-RANGE CONFORMATIONAL CHANGE IN THE FREE ENZYME
Descriptor:PHOSPHORYLATED ISOCITRATE DEHYDROGENASE
Authors:Hurley, J.H., Dean, A.M., Thorsness, P.E., Koshlandjunior, D.E., Stroud, R.M.
Deposit date:1989-12-28
Release date:1991-01-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Regulation of isocitrate dehydrogenase by phosphorylation involves no long-range conformational change in the free enzyme.
J.Biol.Chem., 265, 1990
1GLA
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STRUCTURE OF THE REGULATORY COMPLEX OF ESCHERICHIA COLI IIIGLC WITH GLYCEROL KINASE
Descriptor:GLUCOSE-SPECIFIC PROTEIN IIIGlc, GLYCEROL KINASE, GLYCEROL
Authors:Hurley, J.H., Worthylake, D., Faber, H.R., Meadow, N.D., Roseman, S., Pettigrew, D.W., Remington, S.J.
Deposit date:1992-10-28
Release date:1993-10-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of the regulatory complex of Escherichia coli IIIGlc with glycerol kinase.
Science, 259, 1993
1GLB
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STRUCTURE OF THE REGULATORY COMPLEX OF ESCHERICHIA COLI IIIGLC WITH GLYCEROL KINASE
Descriptor:GLUCOSE-SPECIFIC PROTEIN IIIGlc, GLYCEROL KINASE, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Hurley, J.H., Worthylake, D., Faber, H.R., Meadow, N.D., Roseman, S., Pettigrew, D.W., Remington, S.J.
Deposit date:1992-10-28
Release date:1993-10-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of the regulatory complex of Escherichia coli IIIGlc with glycerol kinase.
Science, 259, 1993
1HEX
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STRUCTURE OF 3-ISOPROPYLMALATE DEHYDROGENASE IN COMPLEX WITH NAD+: LIGAND-INDUCED LOOP-CLOSING AND MECHANISM FOR COFACTOR SPECIFICITY
Descriptor:3-ISOPROPYLMALATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Hurley, J.H.
Deposit date:1994-09-09
Release date:1994-12-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of 3-isopropylmalate dehydrogenase in complex with NAD+: ligand-induced loop closing and mechanism for cofactor specificity.
Structure, 2, 1994
1ISO
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ISOCITRATE DEHYDROGENASE: STRUCTURE OF AN ENGINEERED NADP+--> NAD+ SPECIFICITY-REVERSAL MUTANT
Descriptor:ISOCITRATE DEHYDROGENASE, SULFATE ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Hurley, J.H.
Deposit date:1996-03-01
Release date:1996-12-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Determinants of cofactor specificity in isocitrate dehydrogenase: structure of an engineered NADP+ --> NAD+ specificity-reversal mutant.
Biochemistry, 35, 1996
1L77
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DESIGN AND STRUCTURAL ANALYSIS OF ALTERNATIVE HYDROPHOBIC CORE PACKING ARRANGEMENTS IN BACTERIOPHAGE T4 LYSOZYME
Descriptor:T4 LYSOZYME, CHLORIDE ION, BETA-MERCAPTOETHANOL
Authors:Hurley, J.H., Matthews, B.W.
Deposit date:1991-11-12
Release date:1993-04-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Design and structural analysis of alternative hydrophobic core packing arrangements in bacteriophage T4 lysozyme.
J.Mol.Biol., 224, 1992
1L79
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DESIGN AND STRUCTURAL ANALYSIS OF ALTERNATIVE HYDROPHOBIC CORE PACKING ARRANGEMENTS IN BACTERIOPHAGE T4 LYSOZYME
Descriptor:T4 LYSOZYME, CHLORIDE ION, BETA-MERCAPTOETHANOL
Authors:Hurley, J.H., Matthews, B.W.
Deposit date:1991-11-12
Release date:1993-04-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Design and structural analysis of alternative hydrophobic core packing arrangements in bacteriophage T4 lysozyme.
J.Mol.Biol., 224, 1992
1L80
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DESIGN AND STRUCTURAL ANALYSIS OF ALTERNATIVE HYDROPHOBIC CORE PACKING ARRANGEMENTS IN BACTERIOPHAGE T4 LYSOZYME
Descriptor:T4 LYSOZYME, CHLORIDE ION, BETA-MERCAPTOETHANOL
Authors:Hurley, J.H., Matthews, B.W.
Deposit date:1991-11-12
Release date:1993-04-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Design and structural analysis of alternative hydrophobic core packing arrangements in bacteriophage T4 lysozyme.
J.Mol.Biol., 224, 1992
1L81
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DESIGN AND STRUCTURAL ANALYSIS OF ALTERNATIVE HYDROPHOBIC CORE PACKING ARRANGEMENTS IN BACTERIOPHAGE T4 LYSOZYME
Descriptor:T4 LYSOZYME, CHLORIDE ION, BETA-MERCAPTOETHANOL
Authors:Hurley, J.H., Matthews, B.W.
Deposit date:1991-11-12
Release date:1993-04-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Design and structural analysis of alternative hydrophobic core packing arrangements in bacteriophage T4 lysozyme.
J.Mol.Biol., 224, 1992
1L82
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DESIGN AND STRUCTURAL ANALYSIS OF ALTERNATIVE HYDROPHOBIC CORE PACKING ARRANGEMENTS IN BACTERIOPHAGE T4 LYSOZYME
Descriptor:T4 LYSOZYME, CHLORIDE ION, BETA-MERCAPTOETHANOL
Authors:Hurley, J.H., Matthews, B.W.
Deposit date:1991-11-12
Release date:1993-04-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Design and structural analysis of alternative hydrophobic core packing arrangements in bacteriophage T4 lysozyme.
J.Mol.Biol., 224, 1992
2L78
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DESIGN AND STRUCTURAL ANALYSIS OF ALTERNATIVE HYDROPHOBIC CORE PACKING ARRANGEMENTS IN BACTERIOPHAGE T4 LYSOZYME
Descriptor:T4 LYSOZYME, CHLORIDE ION, BETA-MERCAPTOETHANOL
Authors:Hurley, J.H., Matthews, B.W.
Deposit date:1992-01-22
Release date:1993-04-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Design and structural analysis of alternative hydrophobic core packing arrangements in bacteriophage T4 lysozyme.
J.Mol.Biol., 224, 1992
1VFY
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PHOSPHATIDYLINOSITOL-3-PHOSPHATE BINDING FYVE DOMAIN OF VPS27P PROTEIN FROM SACCHAROMYCES CEREVISIAE
Descriptor:PHOSPHATIDYLINOSITOL-3-PHOSPHATE BINDING FYVE DOMAIN OF PROTEIN VPS27, ZINC ION
Authors:Hurley, J.H., Misra, S.
Deposit date:1999-04-26
Release date:1999-05-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Crystal structure of a phosphatidylinositol 3-phosphate-specific membrane-targeting motif, the FYVE domain of Vps27p.
Cell(Cambridge,Mass.), 97, 1999
3P9G
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CRYSTAL STRUCTURE OF THE TSG101 UEV DOMAIN IN COMPLEX WITH FA459 PEPTIDE
Descriptor:Tumor susceptibility gene 101 protein, Gag polyprotein
Authors:Hurley, J.H., Im, Y.J.
Deposit date:2010-10-17
Release date:2011-06-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Elucidation of New Binding Interactions with the Tumor Susceptibility Gene 101 (Tsg101) Protein Using Modified HIV-1 Gag-p6 Derived Peptide Ligands.
ACS Med Chem Lett, 2, 2011
3P9H
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CRYSTAL STRUCTURE OF THE TSG101 UEV DOMAIN IN COMPLEX WITH FA258 PEPTIDE
Descriptor:Tumor susceptibility gene 101 protein, Gag polyprotein
Authors:Hurley, J.H., Im, Y.J.
Deposit date:2010-10-17
Release date:2011-06-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Elucidation of New Binding Interactions with the Tumor Susceptibility Gene 101 (Tsg101) Protein Using Modified HIV-1 Gag-p6 Derived Peptide Ligands.
ACS Med Chem Lett, 2, 2011
4NEE
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CRYSTAL STRUCTURE OF AP-2 ALPHA/SIMGA2 COMPLEX BOUND TO HIV-1 NEF
Descriptor:AP-2 complex subunit sigma, AP-2 complex subunit alpha-2, Protein Nef
Authors:Hurley, J.H., Bonifacino, J.S., Ren, X., Park, S.Y.
Deposit date:2013-10-29
Release date:2014-01-29
Last modified:2014-03-05
Method:X-RAY DIFFRACTION (2.8841 Å)
Cite:How HIV-1 Nef hijacks the AP-2 clathrin adaptor to downregulate CD4.
Elife, 3, 2014
1GRO
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REGULATORY AND CATALYTIC MECHANISMS IN ESCHERICHIA COLI ISOCITRATE DEHYDROGENASE: MULTIPLE ROLES FOR N115
Descriptor:ISOCITRATE DEHYDROGENASE, MAGNESIUM ION, ISOCITRIC ACID
Authors:Grobler, J.A., Hurley, J.H.
Deposit date:1995-10-12
Release date:1996-04-03
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Second-site suppression of regulatory phosphorylation in Escherichia coli isocitrate dehydrogenase.
Protein Sci., 5, 1996
1GRP
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REGULATORY AND CATALYTIC MECHANISMS IN ESCHERICHIA COLI ISOCITRATE DEHYDROGENASE: MULTIPLE ROLES FOR N115
Descriptor:ISOCITRATE DEHYDROGENASE, MAGNESIUM ION, ISOCITRIC ACID
Authors:Grobler, J.A., Hurley, J.H.
Deposit date:1995-10-12
Release date:1996-04-03
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Second-site suppression of regulatory phosphorylation in Escherichia coli isocitrate dehydrogenase.
Protein Sci., 5, 1996
1P3Q
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MECHANISM OF UBIQUITIN RECOGNITION BY THE CUE DOMAIN OF VPS9
Descriptor:Vacuolar protein sorting-associated protein VPS9, Ubiquitin
Authors:Prag, G., Misra, S., Jones, E.A., Ghirlando, R., Davies, B.A., Horazdovsky, B.F., Hurley, J.H.
Deposit date:2003-04-18
Release date:2003-06-24
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Mechanism of Ubiquitin Recognition by the CUE Domain of Vps9p.
Cell(Cambridge,Mass.), 113, 2003
1QAS
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1-PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE PHOSPHODIESTERASE DELTA 1
Descriptor:PHOSPHOLIPASE C DELTA-1
Authors:Grobler, J.A., Hurley, J.H.
Deposit date:1996-08-02
Release date:1997-02-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:C2 domain conformational changes in phospholipase C-delta 1.
Nat.Struct.Biol., 3, 1996