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8FTU
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BU of 8ftu by Molmil
Crystal structure of the SNARE Use1 bound to Dsl1 complex subunits Sec39 and Dsl1, Revised Use1 structure
Descriptor: Protein transport protein DSL1, Protein transport protein SEC39, Vesicle transport protein USE1
Authors:Travis, S.M, Jeffrey, P.D, Hughson, F.M.
Deposit date:2023-01-13
Release date:2023-03-01
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (5.73 Å)
Cite:Structure of a membrane tethering complex incorporating multiple SNAREs.
Nat.Struct.Mol.Biol., 31, 2024
8EKI
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BU of 8eki by Molmil
CryoEM structure of the Dsl1 complex bound to SNAREs Sec20 and Use1
Descriptor: Protein transport protein DSL1, Protein transport protein SEC20, Protein transport protein SEC39, ...
Authors:DAmico, K.A, Jeffrey, P.D, Hughson, F.M.
Deposit date:2022-09-21
Release date:2023-10-04
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Structure of a membrane tethering complex incorporating multiple SNAREs.
Nat.Struct.Mol.Biol., 31, 2024
6U3W
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BU of 6u3w by Molmil
Crystal structure of yeast alpha/epsilon-COP of the COPI vesicular coat
Descriptor: Coatomer subunit alpha, Coatomer subunit epsilon, GLYCEROL
Authors:Travis, S.M, Hughson, F.M.
Deposit date:2019-08-22
Release date:2019-11-13
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.394 Å)
Cite:Roles of singleton tryptophan motifs in COPI coat stability and vesicle tethering.
Proc.Natl.Acad.Sci.USA, 116, 2019
1ZHH
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BU of 1zhh by Molmil
Crystal Structure of the Apo Form of Vibrio Harveyi LUXP Complexed with the Periplasmic Domain of LUXQ
Descriptor: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Autoinducer 2 sensor kinase/phosphatase luxQ, Autoinducer 2-binding periplasmic protein luxP
Authors:Neiditch, M.B, Federle, M.J, Miller, S.T, Bassler, B.L, Hughson, F.M.
Deposit date:2005-04-25
Release date:2005-05-24
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Regulation of LuxPQ Receptor Activity by the Quorum-Sensing Signal Autoinducer-2.
Mol.Cell, 18, 2005
8CUK
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BU of 8cuk by Molmil
X-ray Structure of the WD40 domain of HOPS subunit Vps11 from Yeast
Descriptor: E3 ubiquitin-protein ligase PEP5
Authors:Port, S.A, Baker, R.W, Jeffrey, P.D, Hughson, F.M.
Deposit date:2022-05-17
Release date:2022-05-25
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:X-ray Structure of the WD40 domain of HOPS subunit Vps11 from Yeast
to be published
8DIT
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BU of 8dit by Molmil
Cryo-EM structure of a HOPS core complex containing Vps33, Vps16, and Vps18
Descriptor: Vacuolar protein sorting-associated protein 16, Vacuolar protein sorting-associated protein 18, Vacuolar protein sorting-associated protein 33
Authors:Port, S.A, Farrell, P.D, Jeffrey, P.D, DiMaio, F, Hughson, F.M.
Deposit date:2022-06-29
Release date:2022-08-31
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (5.1 Å)
Cite:Cryo-EM structure of the HOPS core complex and its implication for SNARE assembly
To Be Published
4U6U
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BU of 4u6u by Molmil
Crystal Structure of the Cog5-Cog7 complex from Kluyveromyces lactis
Descriptor: Cog5, Cog7
Authors:Ha, J.Y, Jeffrey, P.D, Hughson, F.M.
Deposit date:2014-07-29
Release date:2014-10-22
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3 Å)
Cite:Cog5-Cog7 crystal structure reveals interactions essential for the function of a multisubunit tethering complex.
Proc.Natl.Acad.Sci.USA, 111, 2014
1TM2
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BU of 1tm2 by Molmil
Crystal Structure of the apo form of the Salmonella typhimurium AI-2 receptor LsrB
Descriptor: sugar transport protein
Authors:Miller, S.T, Xavier, K.B, Campagna, S.R, Taga, M.E, Semmelhack, M.F, Bassler, B.L, Hughson, F.M.
Deposit date:2004-06-10
Release date:2004-09-28
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Salmonella typhimurium Recognizes a Chemically Distinct Form of the Bacterial Quorum-Sensing Signal AI-2
Mol.Cell, 15, 2004
1TJY
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BU of 1tjy by Molmil
Crystal Structure of Salmonella typhimurium AI-2 receptor LsrB in complex with R-THMF
Descriptor: (2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran, sugar transport protein
Authors:Miller, S.T, Xavier, K.B, Campagna, S.R, Taga, M.E, Semmelhack, M.F, Bassler, B.L, Hughson, F.M.
Deposit date:2004-06-07
Release date:2004-09-28
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Salmonella typhimurium Recognizes a Chemically Distinct Form of the Bacterial Quorum-Sensing Signal AI-2
Mol.Cell, 15, 2004
1HTM
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BU of 1htm by Molmil
STRUCTURE OF INFLUENZA HAEMAGGLUTININ AT THE PH OF MEMBRANE FUSION
Descriptor: HEMAGGLUTININ HA1 CHAIN, HEMAGGLUTININ HA2 CHAIN
Authors:Bullough, P.A, Hughson, F.M, Skehel, J.J, Wiley, D.C.
Deposit date:1994-11-02
Release date:1995-02-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of influenza haemagglutinin at the pH of membrane fusion.
Nature, 371, 1994
6U3V
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BU of 6u3v by Molmil
Crystal structure of human alpha/epsilon-COP of the COPI vesicular coat bound to alpha-COP STM1
Descriptor: Coatomer subunit alpha, Coatomer subunit epsilon
Authors:Travis, S.M, Hughson, F.M.
Deposit date:2019-08-22
Release date:2019-11-13
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.96 Å)
Cite:Roles of singleton tryptophan motifs in COPI coat stability and vesicle tethering.
Proc.Natl.Acad.Sci.USA, 116, 2019
6TZT
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BU of 6tzt by Molmil
Crystal structure of human alpha/epsilon-COP of the COPI vesicular coat bound to alpha-COP STM2
Descriptor: Coatomer subunit alpha, Coatomer subunit epsilon
Authors:Travis, S.M, Hughson, F.M.
Deposit date:2019-08-13
Release date:2019-11-13
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.065 Å)
Cite:Roles of singleton tryptophan motifs in COPI coat stability and vesicle tethering.
Proc.Natl.Acad.Sci.USA, 116, 2019
6WC3
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BU of 6wc3 by Molmil
Crystal structure of the SNARE Sec20 bound to Dsl1 complex subunit Tip20
Descriptor: Protein transport protein SEC20, Protein transport protein TIP20
Authors:Travis, S.M, Jeffrey, P.D, Hughson, F.M.
Deposit date:2020-03-29
Release date:2020-05-27
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.203 Å)
Cite:Structural basis for the binding of SNAREs to the multisubunit tethering complex Dsl1.
J.Biol.Chem., 295, 2020
1EZ3
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BU of 1ez3 by Molmil
CRYSTAL STRUCTURE OF THE NEURONAL T-SNARE SYNTAXIN-1A
Descriptor: SYNTAXIN-1A
Authors:Lerman, J.C, Robblee, J, Fairman, R, Hughson, F.M.
Deposit date:2000-05-09
Release date:2000-06-07
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural analysis of the neuronal SNARE protein syntaxin-1A.
Biochemistry, 39, 2000
1FIO
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BU of 1fio by Molmil
CRYSTAL STRUCTURE OF YEAST T-SNARE PROTEIN SSO1
Descriptor: SSO1 PROTEIN, ZINC ION
Authors:Munson, M, Chen, X, Cocina, A.E, Schultz, S.M, Hughson, F.M.
Deposit date:2000-08-04
Release date:2000-10-11
Last modified:2022-12-21
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Interactions within the yeast t-SNARE Sso1p that control SNARE complex assembly.
Nat.Struct.Biol., 7, 2000
6XJL
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BU of 6xjl by Molmil
Structure of the SM protein Vps45
Descriptor: Vps45
Authors:Jeffrey, P.D, Shimamura, G.S, Allen, F, Hughson, F.M.
Deposit date:2020-06-24
Release date:2020-08-19
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Sec1/Munc18 protein Vps45 holds the Qa-SNARE Tlg2 in an open conformation.
Elife, 9, 2020
6XM1
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BU of 6xm1 by Molmil
SM Protein Vps45 in Complex with Qa SNARE Tlg2
Descriptor: Tlg2 Qa SNARE, Vps45
Authors:Jeffrey, P.D, Eisemann, T.J, Hughson, F.M.
Deposit date:2020-06-29
Release date:2020-08-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The Sec1/Munc18 protein Vps45 holds the Qa-SNARE Tlg2 in an open conformation.
Elife, 9, 2020
6XMD
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BU of 6xmd by Molmil
SM Protein Vps45 in Complex with Qa SNARE Tlg2 (1-310)
Descriptor: Tlg2 Qa SNARE, Vps45
Authors:Jeffrey, P.D, Eisemann, T.J, Hughson, F.M.
Deposit date:2020-06-30
Release date:2020-08-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:The Sec1/Munc18 protein Vps45 holds the Qa-SNARE Tlg2 in an open conformation.
Elife, 9, 2020
4KMO
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BU of 4kmo by Molmil
Crystal Structure of the Vps33-Vps16 HOPS subcomplex from Chaetomium thermophilum
Descriptor: Putative vacuolar protein sorting-associated protein, SULFATE ION, Small conjugating protein ligase-like protein
Authors:Baker, R.W, Jeffrey, P.D, Hughson, F.M.
Deposit date:2013-05-08
Release date:2013-06-26
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structures of the Sec1/Munc18 (SM) Protein Vps33, Alone and Bound to the Homotypic Fusion and Vacuolar Protein Sorting (HOPS) Subunit Vps16*
Plos One, 8, 2013
4L9O
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BU of 4l9o by Molmil
Crystal Structure of the Sec13-Sec16 blade-inserted complex from Pichia pastoris
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ...
Authors:McMahon, C, Jeffrey, P.D, Hughson, F.M.
Deposit date:2013-06-18
Release date:2013-10-02
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Sec16 influences transitional ER sites by regulating rather than organizing COPII.
Mol Biol Cell, 24, 2013
1OT8
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BU of 1ot8 by Molmil
Structure of the Ankyrin Domain of the Drosophila Notch Receptor
Descriptor: MAGNESIUM ION, Neurogenic locus Notch protein
Authors:Zweifel, M.E, Leahy, D.J, Hughson, F.M, Barrick, D.
Deposit date:2003-03-21
Release date:2003-10-28
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure and stability of the ankyrin domain of the Drosophila Notch receptor
Protein Sci., 12, 2003
1JX6
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BU of 1jx6 by Molmil
CRYSTAL STRUCTURE OF LUXP FROM VIBRIO HARVEYI COMPLEXED WITH AUTOINDUCER-2
Descriptor: 3A-METHYL-5,6-DIHYDRO-FURO[2,3-D][1,3,2]DIOXABOROLE-2,2,6,6A-TETRAOL, CALCIUM ION, LUXP PROTEIN
Authors:Chen, X, Schauder, S, Potier, N, Van Dorsselaer, A, Pelczer, I, BassleR, B.L, Hughson, F.M.
Deposit date:2001-09-05
Release date:2002-02-04
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural identification of a bacterial quorum-sensing signal containing boron.
Nature, 415, 2002
3ETU
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BU of 3etu by Molmil
Crystal structure of yeast Dsl1p
Descriptor: Protein transport protein DSL1
Authors:Ren, Y, Jeffrey, P.D, Hughson, F.M.
Deposit date:2008-10-08
Release date:2009-01-20
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural characterization of Tip20p and Dsl1p, subunits of the Dsl1p vesicle tethering complex.
Nat.Struct.Mol.Biol., 16, 2009
3ETV
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BU of 3etv by Molmil
Crystal structure of a Tip20p-Dsl1p fusion protein
Descriptor: Protein transport protein TIP20, Protein transport protein DSL1 chimera
Authors:Ren, Y, Jeffrey, P.D, Hughson, F.M.
Deposit date:2008-10-08
Release date:2009-01-20
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Structural characterization of Tip20p and Dsl1p, subunits of the Dsl1p vesicle tethering complex.
Nat.Struct.Mol.Biol., 16, 2009
3FHN
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BU of 3fhn by Molmil
Structure of Tip20p
Descriptor: Protein transport protein TIP20
Authors:Tripathi, A, Ren, Y, Jeffrey, P.D, Hughson, F.M.
Deposit date:2008-12-09
Release date:2009-01-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural characterization of Tip20p and Dsl1p, subunits of the Dsl1p vesicle tethering complex.
Nat.Struct.Mol.Biol., 16, 2009

 

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