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4DL2
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HUMAN DNA POLYMERASE ETA INSERTING DCMPNPP OPPOSITE CG TEMPLATE (GG0A)
Descriptor:DNA polymerase eta, DNA (5'-D(*AP*CP*GP*GP*CP*TP*CP*AP*CP*AP*CP*T)-3'), DNA (5'-D(*TP*AP*GP*TP*GP*TP*GP*AP*G)-3'), ...
Authors:Zhao, Y., Biertumpfel, C., Gregory, M., Hua, Y., Hanaoka, F., Yang, W.
Deposit date:2012-02-05
Release date:2012-05-09
Last modified:2013-06-26
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural Basis for Chemoresistance to Cisplatin Mediated by DNA Polymerase eta
Proc.Natl.Acad.Sci.USA, 109, 2012
4DL3
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HUMAN DNA POLYMERASE ETA INSERTING DCMPNPP OPPOSITE GG TEMPLATE (GG0B).
Descriptor:DNA polymerase eta, DNA (5'-D(*TP*AP*CP*GP*GP*TP*CP*AP*CP*AP*CP*T)-3'), DNA (5'-D(*TP*AP*GP*TP*GP*TP*GP*AP*C)-3'), ...
Authors:Zhao, Y., Biertumpfel, C., Gregory, M., Hua, Y., Hanaoka, F., Yang, W.
Deposit date:2012-02-05
Release date:2012-05-09
Last modified:2013-06-26
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Basis for Chemoresistance to Cisplatin Mediated by DNA Polymerase eta
Proc.Natl.Acad.Sci.USA, 109, 2012
4DL4
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HUMAN DNA POLYMERASE ETA INSERTING DCMPNPP OPPOSITE THE 3'G OF CISPLATIN CROSSLINKED GS (PT-GG1).
Descriptor:DNA polymerase eta, DNA (5'-D(P*GP*GP*CP*TP*CP*AP*CP*AP*CP*T)-3'), DNA (5'-D(*TP*AP*GP*TP*GP*TP*GP*AP*G)-3'), ...
Authors:Zhao, Y., Biertumpfel, C., Gregory, M., Hua, Y.-J., Hanaoka, F., Yang, W.
Deposit date:2012-02-05
Release date:2012-05-09
Last modified:2013-07-17
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Basis for Chemoresistance to Cisplatin Mediated by DNA Polymerase eta
Proc.Natl.Acad.Sci.USA, 109, 2012
4DL5
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HUMAN DNA POLYMERASE ETA INSERTING DCMPNPP OPPOSITE THE 5'G OF CISPLATIN CROSSLINKED GS (PT-GG2).
Descriptor:DNA polymerase eta, DNA (5'-D(*TP*AP*CP*GP*GP*TP*CP*AP*CP*AP*CP*T)-3'), DNA (5'-D(P*TP*AP*GP*TP*GP*TP*GP*AP*C)-3'), ...
Authors:Zhao, Y., Biertumpfel, C., Gregory, M., Hanaoka, F., Hua, Y., Yang, W.
Deposit date:2012-02-05
Release date:2012-05-09
Last modified:2014-10-08
Method:X-RAY DIFFRACTION (2.92 Å)
Cite:Structural Basis for Chemoresistance to Cisplatin Mediated by DNA Polymerase eta
Proc.Natl.Acad.Sci.USA, 109, 2012
4DL6
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HUMAN DNA POLYMERASE ETA EXTENDING PRIMER IMMEDIATELY AFTER CISPLATIN CROSSLINK (PT-GG3).
Descriptor:DNA polymerase eta, DNA (5'-D(*TP*AP*TP*CP*GP*GP*CP*AP*CP*AP*CP*T)-3'), DNA (5'-D(*TP*AP*GP*TP*GP*TP*GP*CP*C)-3'), ...
Authors:Zhao, Y., Biertumpfel, C., Gregory, M., Hua, Y., Hanaoka, F., Yang, W.
Deposit date:2012-02-05
Release date:2012-05-09
Last modified:2013-06-26
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Basis for Chemoresistance to Cisplatin Mediated by DNA Polymerase eta
Proc.Natl.Acad.Sci.USA, 109, 2012
4DL7
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HUMAN DNA POLYMERASE ETA FAILS TO EXTEND PRIMER 2 NUCLEOTIDE AFTER CISPLATIN CROSSLINK (PT-GG4).
Descriptor:DNA polymerase eta, DNA (5'-D(*TP*AP*CP*TP*CP*GP*GP*TP*CP*AP*CP*T)-3'), DNA (5'-D(*TP*AP*GP*TP*GP*AP*CP*CP*G)-3'), ...
Authors:Zhao, Y., Biertumpfel, C., Gregory, M., Hua, Y., Hanaoka, F., Yang, W.
Deposit date:2012-02-05
Release date:2012-05-09
Last modified:2013-07-17
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Structural Basis for Chemoresistance to Cisplatin Mediated by DNA Polymerase eta
Proc.Natl.Acad.Sci.USA, 109, 2012
4J9K
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HUMAN DNA POLYMERASE ETA-DNA TERNARY COMPLEX: MISINCORPORATION G OPPOSITE T AFTER A T AT THE PRIMER 3' END (TA/G)
Descriptor:DNA polymerase eta, DNA, MAGNESIUM ION, ...
Authors:Zhao, Y., Gregory, M., Biertumpfel, C., Hua, Y., Hanaoka, F., Yang, W.
Deposit date:2013-02-16
Release date:2013-05-01
Last modified:2013-08-28
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Mechanism of somatic hypermutation at the WA motif by human DNA polymerase eta.
Proc.Natl.Acad.Sci.USA, 110, 2013
4J9L
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HUMAN DNA POLYMERASE ETA-DNA TERNARY COMPLEX: MISINCORPORATION G OPPOSITE T AFTER A C AT THE PRIMER 3' END (CA/G)
Descriptor:DNA polymerase eta, DNA, MAGNESIUM ION, ...
Authors:Zhao, Y., Gregory, M., Biertumpfel, C., Hua, Y., Hanaoka, F., Yang, W.
Deposit date:2013-02-16
Release date:2013-05-01
Last modified:2013-08-28
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Mechanism of somatic hypermutation at the WA motif by human DNA polymerase eta.
Proc.Natl.Acad.Sci.USA, 110, 2013
4J9M
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HUMAN DNA POLYMERASE ETA-DNA TERNARY COMPLEX: MISINCORPORATION G OPPOSITE T AFTER AN A AT THE PRIMER 3' END (AA/G)
Descriptor:DNA polymerase eta, DNA, MAGNESIUM ION, ...
Authors:Zhao, Y., Gregory, M., Biertumpfel, C., Hua, Y., Hanaoka, F., Yang, W.
Deposit date:2013-02-16
Release date:2013-05-01
Last modified:2013-08-28
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Mechanism of somatic hypermutation at the WA motif by human DNA polymerase eta.
Proc.Natl.Acad.Sci.USA, 110, 2013
4J9N
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HUMAN DNA POLYMERASE ETA-DNA TERNARY COMPLEX: MISINCORPORATION G OPPOSITE T AFTER A G AT THE PRIMER 3' END (GA/G)
Descriptor:DNA polymerase eta, DNA, MAGNESIUM ION, ...
Authors:Zhao, Y., Gregory, M., Biertumpfel, C., Hua, Y., Hanaoka, F., Yang, W.
Deposit date:2013-02-16
Release date:2013-05-01
Last modified:2013-08-28
Method:X-RAY DIFFRACTION (1.956 Å)
Cite:Mechanism of somatic hypermutation at the WA motif by human DNA polymerase eta.
Proc.Natl.Acad.Sci.USA, 110, 2013
4J9O
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HUMAN DNA POLYMERASE ETA-DNA TERNARY COMPLEX: PRIMER EXTENSION AFTER A T:G MISPAIR
Descriptor:DNA polymerase eta, DNA (5'-D(*T*AP*CP*TP*TP*AP*TP*GP*AP*CP*GP*T)-3'), DNA (5'-D(*T*AP*CP*GP*TP*CP*AP*TP*G)-3'), ...
Authors:Zhao, Y., Gregory, M., Biertumpfel, C., Hua, Y., Hanaoka, F., Yang, W.
Deposit date:2013-02-16
Release date:2013-05-01
Last modified:2013-08-28
Method:X-RAY DIFFRACTION (2.597 Å)
Cite:Mechanism of somatic hypermutation at the WA motif by human DNA polymerase eta.
Proc.Natl.Acad.Sci.USA, 110, 2013
4J9P
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HUMAN DNA POLYMERASE ETA-DNA POSTINSERTION BINARY COMPLEX WITH TA BASE PAIR
Descriptor:DNA polymerase eta, DNA (5'-D(*C*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), DNA (5'-D(*TP*AP*GP*CP*GP*TP*CP*AP*TP*A)-3'), ...
Authors:Zhao, Y., Gregory, M., Biertumpfel, C., Hua, Y., Hanaoka, F., Yang, W.
Deposit date:2013-02-16
Release date:2013-05-01
Last modified:2013-08-28
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Mechanism of somatic hypermutation at the WA motif by human DNA polymerase eta.
Proc.Natl.Acad.Sci.USA, 110, 2013
4J9Q
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HUMAN DNA POLYMERASE ETA-DNA POSTINSERTION BINARY COMPLEX WITH TG MISPAIR
Descriptor:DNA polymerase eta, DNA (5'-D(*TP*C*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), DNA (5'-D(*TP*AP*GP*CP*GP*TP*CP*AP*TP*G)-3'), ...
Authors:Zhao, Y., Gregory, M., Biertumpfel, C., Hua, Y., Hanaoka, F., Yang, W.
Deposit date:2013-02-16
Release date:2013-05-01
Last modified:2013-08-28
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Mechanism of somatic hypermutation at the WA motif by human DNA polymerase eta.
Proc.Natl.Acad.Sci.USA, 110, 2013
4J9R
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HUMAN DNA POLYMERASE ETA-DNA TRANSLOCATED BINARY COMPLEX WITH TG MISPAIR
Descriptor:DNA polymerase eta, DNA (5'-D(*T*AP*CP*TP*TP*AP*TP*GP*AP*CP*GP*T)-3'), DNA (5'-D(P*TP*AP*CP*GP*TP*CP*AP*TP*G)-3'), ...
Authors:Zhao, Y., Gregory, M., Biertumpfel, C., Hua, Y., Hanaoka, F., Yang, W.
Deposit date:2013-02-16
Release date:2013-05-01
Last modified:2013-08-28
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Mechanism of somatic hypermutation at the WA motif by human DNA polymerase eta.
Proc.Natl.Acad.Sci.USA, 110, 2013
4J9S
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HUMAN DNA POLYMERASE ETA-DNA TRANSLOCATED BINARY COMPLEX: WITH TA BASE PAIR
Descriptor:DNA polymerase eta, DNA (5'-D(*T*AP*TP*TP*TP*AP*TP*GP*AP*CP*GP*T)-3'), DNA (5'-D(*TP*AP*CP*GP*TP*CP*AP*TP*A)-3'), ...
Authors:Zhao, Y., Gregory, M., Biertumpfel, C., Hua, Y., Hanaoka, F., Yang, W.
Deposit date:2013-02-16
Release date:2013-05-01
Last modified:2013-08-28
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Mechanism of somatic hypermutation at the WA motif by human DNA polymerase eta.
Proc.Natl.Acad.Sci.USA, 110, 2013
4OCH
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APO STRUCTURE OF SMR DOMAIN OF MUTS2 FROM DEINOCOCCUS RADIODURANS
Descriptor:Endonuclease MutS2, GLYCEROL
Authors:Zhang, H., Zhao, Y., Xu, Q., Hua, Y.J.
Deposit date:2014-01-09
Release date:2014-06-25
Last modified:2014-08-20
Method:X-RAY DIFFRACTION (1.4001 Å)
Cite:Structural and functional studies of MutS2 from Deinococcus radiodurans.
Dna Repair, 21, 2014
4OD6
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STRUCTURE OF SMR DOMAIN OF MUTS2 FROM DEINOCOCCUS RADIODURANS, MN2+ SOAKED
Descriptor:Endonuclease MutS2
Authors:Zhang, H., Zhao, Y., Xu, Q., Hua, Y.J.
Deposit date:2014-01-10
Release date:2014-06-25
Last modified:2014-08-20
Method:X-RAY DIFFRACTION (1.199 Å)
Cite:Structural and functional studies of MutS2 from Deinococcus radiodurans.
Dna Repair, 21, 2014
4ECQ
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HUMAN DNA POLYMERASE ETA- DNA TERNARY COMPLEX: AT CRYSTAL AT PH6.8(K+ MES) WITH 1 CA2+ ION
Descriptor:DNA polymerase eta, DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*TP*A)-3'), ...
Authors:Nakamura, T., Zhao, Y., Yang, W.
Deposit date:2012-03-26
Release date:2012-07-11
Last modified:2012-07-25
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Watching DNA polymerase eta make a phosphodiester bond
Nature, 487, 2012
4ECR
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HUMAN DNA POLYMERASE ETA - DNA TERNARY COMPLEX: REACTION IN THE AT CRYSTAL AT PH 7.0 FOR 40 SEC
Descriptor:DNA polymerase eta, DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ...
Authors:Nakamura, T., Zhao, Y., Yang, W.
Deposit date:2012-03-26
Release date:2012-07-11
Last modified:2012-07-25
Method:X-RAY DIFFRACTION (1.892 Å)
Cite:Watching DNA polymerase eta make a phosphodiester bond
Nature, 487, 2012
4ECS
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HUMAN DNA POLYMERASE ETA - DNA TERNARY COMPLEX: REACTION IN THE AT CRYSTAL AT PH 7.0 FOR 80 SEC
Descriptor:DNA polymerase eta, DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*TP*A)-3'), ...
Authors:Nakamura, T., Zhao, Y., Yang, W.
Deposit date:2012-03-26
Release date:2012-07-11
Last modified:2012-07-25
Method:X-RAY DIFFRACTION (1.951 Å)
Cite:Watching DNA polymerase eta make a phosphodiester bond
Nature, 487, 2012
4ECT
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HUMAN DNA POLYMERASE ETA - DNA TERNARY COMPLEX: REACTION IN THE AT CRYSTAL AT PH 7.0 FOR 140 SEC
Descriptor:DNA polymerase eta, DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*TP*A)-3'), ...
Authors:Nakamura, T., Zhao, Y., Yang, W.
Deposit date:2012-03-26
Release date:2012-07-11
Last modified:2012-07-25
Method:X-RAY DIFFRACTION (1.795 Å)
Cite:Watching DNA polymerase eta make a phosphodiester bond
Nature, 487, 2012
4ECU
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HUMAN DNA POLYMERASE ETA - DNA TERNARY COMPLEX: REACTION IN THE AT CRYSTAL AT PH 7.0 FOR 200 SEC
Descriptor:DNA polymerase eta, DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*TP*A)-3'), ...
Authors:Nakamura, T., Zhao, Y., Yang, W.
Deposit date:2012-03-26
Release date:2012-07-11
Last modified:2012-07-25
Method:X-RAY DIFFRACTION (1.949 Å)
Cite:Watching DNA polymerase eta make a phosphodiester bond
Nature, 487, 2012
4ECV
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HUMAN DNA POLYMERASE ETA - DNA TERNARY COMPLEX: REACTION IN THE AT CRYSTAL AT PH 7.0 FOR 230 SEC
Descriptor:DNA polymerase eta, DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*TP*A)-3'), ...
Authors:Nakamura, T., Zhao, Y., Yang, W.
Deposit date:2012-03-26
Release date:2012-07-11
Last modified:2012-07-25
Method:X-RAY DIFFRACTION (1.521 Å)
Cite:Watching DNA polymerase eta make a phosphodiester bond
Nature, 487, 2012
4ECW
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HUMAN DNA POLYMERASE ETA - DNA TERNARY COMPLEX: REACTION IN THE AT CRYSTAL AT PH 7.0 FOR 250 SEC
Descriptor:DNA polymerase eta, DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*TP*A)-3'), ...
Authors:Nakamura, T., Zhao, Y., Yang, W.
Deposit date:2012-03-26
Release date:2012-07-11
Last modified:2012-07-25
Method:X-RAY DIFFRACTION (1.896 Å)
Cite:Watching DNA polymerase eta make a phosphodiester bond
Nature, 487, 2012
4ECX
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HUMAN DNA POLYMERASE ETA - DNA TERNARY COMPLEX: REACTION IN THE AT CRYSTAL AT PH 7.0 FOR 300 SEC
Descriptor:DNA polymerase eta, DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*TP*A)-3'), ...
Authors:Nakamura, T., Zhao, Y., Yang, W.
Deposit date:2012-03-26
Release date:2012-07-11
Last modified:2012-07-25
Method:X-RAY DIFFRACTION (1.744 Å)
Cite:Watching DNA polymerase eta make a phosphodiester bond
Nature, 487, 2012
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