Author results

1NHH
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CRYSTAL STRUCTURE OF N-TERMINAL 40KD MUTL PROTEIN (LN40) COMPLEX WITH ADPNP AND ONE RUBIDIUM
Descriptor:DNA mismatch repair protein mutL, MAGNESIUM ION, RUBIDIUM ION, ...
Authors:Hu, X., Machius, M., Yang, W.
Deposit date:2002-12-19
Release date:2003-06-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Monovalent cation dependence and preference of GHKL ATPases and kinases
FEBS Lett., 544, 2003
1NHI
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CRYSTAL STRUCTURE OF N-TERMINAL 40KD MUTL (LN40) COMPLEX WITH ADPNP AND ONE POTASSIUM
Descriptor:DNA mismatch repair protein mutL, MAGNESIUM ION, POTASSIUM ION, ...
Authors:Hu, X., Machius, M., Yang, W.
Deposit date:2002-12-19
Release date:2003-06-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Monovalent cation dependence and preference of GHKL ATPases and kinases
FEBS Lett., 544, 2003
1NHJ
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CRYSTAL STRUCTURE OF N-TERMINAL 40KD MUTL/A100P MUTANT PROTEIN COMPLEX WITH ADPNP AND ONE SODIUM
Descriptor:DNA mismatch repair protein mutL, SODIUM ION, MAGNESIUM ION, ...
Authors:Hu, X., Machius, M., Yang, W.
Deposit date:2002-12-19
Release date:2003-06-10
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Monovalent cation dependence and preference of GHKL ATPases and kinases
FEBS Lett., 544, 2003
2RB8
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HIGH RESOLUTION DESIGN OF A PROTEIN LOOP
Descriptor:Tenascin
Authors:Hu, X., Wang, H., Ke, H., Kuhlman, B.
Deposit date:2007-09-18
Release date:2007-11-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:High-resolution design of a protein loop.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2RBL
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HIGH RESOLUTION DESIGN OF A PROTEIN LOOP
Descriptor:Tenascin
Authors:Hu, X., Wang, H., Ke, H., Kuhlman, B.
Deposit date:2007-09-19
Release date:2007-11-20
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:High-resolution design of a protein loop.
Proc.Natl.Acad.Sci.Usa, 104, 2007
3B83
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COMPUTER-BASED REDESIGN OF A BETA SANDWICH PROTEIN SUGGESTS THAT EXTENSIVE NEGATIVE DESIGN IS NOT REQUIRED FOR DE NOVO BETA SHEET DESIGN.
Descriptor:TEN-D3
Authors:Hu, X., Ke, H., Kuhlman, B.
Deposit date:2007-10-31
Release date:2008-11-04
Last modified:2013-06-05
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Computer-Based Redesign of a beta Sandwich Protein Suggests that Extensive Negative Design Is Not Required for De Novo beta Sheet Design.
Structure, 16, 2008
3LA1
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HIGH RESOLUTION CRYSTAL STRUCTURE OF CYPET MUTANT A167I
Descriptor:Green fluorescent protein, SODIUM ION
Authors:Hu, X.
Deposit date:2010-01-06
Release date:2011-01-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.29 Å)
Cite:Crystal Structure of CyPet
To be Published
3ROJ
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D-FRUCTOSE 1,6-BISPHOSPHATASE CLASS 2/SEDOHEPTULOSE 1,7-BISPHOSPHATASE OF SYNECHOCYSTIS SP. PCC 6803
Descriptor:D-fructose 1,6-bisphosphatase class 2/sedoheptulose 1,7-bisphosphatase, MAGNESIUM ION, ADENOSINE MONOPHOSPHATE, ...
Authors:Hu, X., Hui, D., Lingling, F., Jian, W.
Deposit date:2011-04-26
Release date:2012-05-02
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:New insights into the structural and interactional basis for a promising route towards fructose-1,6-/sedoheptulose-1,7-bisphosphatases controlling
To be Published
3RPL
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D-FRUCTOSE 1,6-BISPHOSPHATASE CLASS 2/SEDOHEPTULOSE 1,7-BISPHOSPHATASE OF SYNECHOCYSTIS SP. PCC 6803 IN COMPLEX WITH FRUCTOSE-1,6-BISPHOSPHATE
Descriptor:D-fructose 1,6-bisphosphatase class 2/sedoheptulose 1,7-bisphosphatase, MAGNESIUM ION, BETA-FRUCTOSE-1,6-DIPHOSPHATE, ...
Authors:Hu, X., Hui, D., Lingling, F., Jian, W.
Deposit date:2011-04-26
Release date:2012-05-02
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:New insights into the structural and interactional basis for a promising route towards fructose-1,6-/sedoheptulose-1,7-bisphosphatases controlling
To be Published
3URM
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CRYSTAL STRUCTURE OF THE PERIPLASMIC SUGAR BINDING PROTEIN CHVE
Descriptor:Multiple sugar-binding periplasmic receptor ChvE, BETA-D-GALACTOSE
Authors:Hu, X., Zhao, J., Binns, A., Degrado, W.
Deposit date:2011-11-22
Release date:2012-11-28
Last modified:2013-01-23
Method:X-RAY DIFFRACTION (1.801 Å)
Cite:Agrobacterium tumefaciens recognizes its host environment using ChvE to bind diverse plant sugars as virulence signals.
Proc.Natl.Acad.Sci.USA, 110, 2013
3UUG
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CRYSTAL STRUCTURE OF THE PERIPLASMIC SUGAR BINDING PROTEIN CHVE
Descriptor:Multiple sugar-binding periplasmic receptor ChvE, BETA-D-GLUCOPYRANURONIC ACID
Authors:Hu, X., Zhao, J., Binns, A., Degrado, W.
Deposit date:2011-11-28
Release date:2012-11-28
Last modified:2013-01-23
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Agrobacterium tumefaciens recognizes its host environment using ChvE to bind diverse plant sugars as virulence signals.
Proc.Natl.Acad.Sci.USA, 110, 2013
2G6P
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CRYSTAL STRUCTURE OF TRUNCATED (DELTA 1-89) HUMAN METHIONINE AMINOPEPTIDASE TYPE 1 IN COMPLEX WITH PYRIDYL PYRIMIDINE DERIVATIVE
Descriptor:Methionine aminopeptidase 1, COBALT (II) ION, POTASSIUM ION, ...
Authors:Addlagatta, A., Hu, X., Liu, J.O., Matthews, B.W.
Deposit date:2006-02-24
Release date:2006-06-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Identification of Pyridinylpyrimidines as Inhibitors of Human Methionine Aminopeptidases.
Angew.Chem.Int.Ed.Engl., 45, 2006
3GEX
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1.6 ANGSTROM CRYSTAL STRUCTURE OF FLUORESCENT PROTEIN CYPET
Descriptor:Green fluorescent protein
Authors:Hu, X., Liu, R.
Deposit date:2009-02-26
Release date:2010-03-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:1.6 angstrom crystal structure of fluorescent protein Cypet
To be Published
3I19
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1.4 ANGSTROM CRYSTAL STRUCTURE OF FLUORESCENT PROTEIN CYPET
Descriptor:Green fluorescent protein
Authors:Hu, X.
Deposit date:2009-06-25
Release date:2010-06-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.36 Å)
Cite:1.4 Angstrom Crystal Structure of Fluorescent Protein Cypet
To be Published
5GNS
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STRUCTURES OF HUMAN MITOFUSIN 1 PROVIDE INSIGHT INTO MITOCHONDRIAL TETHERING
Descriptor:Mitofusin-1, GUANOSINE-5'-TRIPHOSPHATE
Authors:Qi, Y., Yan, L., Yu, C., Guo, X., Zhou, X., Hu, X., Huang, X., Rao, Z., Lou, Z., Hu, J.
Deposit date:2016-07-24
Release date:2016-12-07
Method:X-RAY DIFFRACTION (2.702 Å)
Cite:Structures of human Mitofusin 1 provide insight into mitochondrial tethering
To Be Published
5CB2
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THE STRUCTURE OF CANDIDA ALBICANS SEY1P IN COMPLEX WITH GMPPNP
Descriptor:Protein SEY1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
Authors:Yan, L., Sun, S., Wang, W., Shi, J., Hu, X., Wang, S., Rao, Z., Hu, J., Lou, Z.
Deposit date:2015-06-30
Release date:2015-09-23
Last modified:2015-10-07
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structures of the yeast dynamin-like GTPase Sey1p provide insight into homotypic ER fusion
J.Cell Biol., 210, 2015
1LGH
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CRYSTAL STRUCTURE OF THE LIGHT-HARVESTING COMPLEX II (B800-850) FROM RHODOSPIRILLUM MOLISCHIANUM
Descriptor:LIGHT HARVESTING COMPLEX II, BACTERIOCHLOROPHYLL A, LYCOPENE, ...
Authors:Koepke, J., Hu, X., Schulten, K., Michel, H.
Deposit date:1996-03-20
Release date:1997-06-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The crystal structure of the light-harvesting complex II (B800-850) from Rhodospirillum molischianum.
Structure, 4, 1996
2XWT
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CRYSTAL STRUCTURE OF THE TSH RECEPTOR IN COMPLEX WITH A BLOCKING TYPE TSHR AUTOANTIBODY
Descriptor:THYROID BLOCKING HUMAN AUTOANTIBODY K1-70 HEAVY CHAIN, THYROID BLOCKING HUMAN AUTOANTIBODY K1-70 LIGHT CHAIN, THYROTROPIN RECEPTOR, ...
Authors:Sanders, J., Sanders, P., Young, S., Kabelis, K., Baker, S., Sullivan, A., Evans, M., Clark, J., Wilmot, J., Hu, X., Roberts, E., Powell, M., Nunez Miguel, R., Furmaniak, J., Rees Smith, B.
Deposit date:2010-11-05
Release date:2011-03-09
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal Structure of the Tsh Receptor (Tshr) Bound to a Blocking-Type Tshr Autoantibody.
J.Mol.Endocrinol., 46, 2011
3RX2
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CRYSTAL STRUCTURE OF HUMAN ALDOSE REDUCTASE COMPLEXED WITH SULINDAC SULFONE
Descriptor:Aldose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 2-[(3Z)-6-fluoranyl-2-methyl-3-[(4-methylsulfonylphenyl)methylidene]inden-1-yl]ethanoic acid
Authors:Zheng, X., Chen, J., Luo, H., Hu, X.
Deposit date:2011-05-10
Release date:2011-11-30
Last modified:2013-07-03
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The molecular basis for inhibition of sulindac and its metabolites towards human aldose reductase
Febs Lett., 586, 2012
3RX3
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CRYSTAL STRUCTURE OF HUMAN ALDOSE REDUCTASE COMPLEXED WITH SULINDAC
Descriptor:Aldose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, [(1Z)-5-fluoro-2-methyl-1-{4-[methylsulfinyl]benzylidene}-1H-inden-3-yl]acetic acid
Authors:Zheng, X., Chen, J., Luo, H., Hu, X.
Deposit date:2011-05-10
Release date:2011-11-30
Last modified:2013-07-03
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The molecular basis for inhibition of sulindac and its metabolites towards human aldose reductase.
Febs Lett., 586, 2012
3RX4
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CRYSTAL STRUCTURE OF HUMAN ALDOSE REDUCTASE COMPLEXED WITH SULINDAC SULFIDE
Descriptor:Aldose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 2-[(3Z)-6-fluoranyl-2-methyl-3-[(4-methylsulfanylphenyl)methylidene]inden-1-yl]ethanoic acid
Authors:Zheng, X., Chen, J., Luo, H., Hu, X.
Deposit date:2011-05-10
Release date:2011-11-30
Last modified:2013-07-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:The molecular basis for inhibition of sulindac and its metabolites towards human aldose reductase.
Febs Lett., 586, 2012
3S3G
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CRYSTAL STRUCTURE OF HUMAN ALDOSE REDUCTASE COMPLEXED WITH TOLMETIN
Descriptor:Aldose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Tolmetin
Authors:Zheng, X., Chen, J., Luo, H., Hu, X.
Deposit date:2011-05-18
Release date:2012-04-04
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The molecular basis for inhibition of sulindac and its metabolites towards human aldose reductase.
Febs Lett., 586, 2012
3V35
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ALDOSE REDUCTASE COMPLEXED WITH A NITRO COMPOUND
Descriptor:Aldose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 2-[(5-nitro-1,3-thiazol-2-yl)carbamoyl]phenyl acetate, ...
Authors:Zheng, X., Zhang, L., Chen, Y., Luo, H., Hu, X.
Deposit date:2011-12-13
Release date:2012-08-29
Last modified:2014-07-23
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Partial inhibition of aldose reductase by nitazoxanide and its molecular basis.
Chemmedchem, 7, 2012
3V36
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ALDOSE REDUCTASE COMPLEXED WITH GLCERALDEHYDE
Descriptor:Aldose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, GLYCERALDEHYDE, ...
Authors:Zheng, X., Zhang, L., Chen, Y., Luo, H., Hu, X.
Deposit date:2011-12-13
Release date:2012-08-29
Last modified:2014-07-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:Partial inhibition of aldose reductase by nitazoxanide and its molecular basis.
Chemmedchem, 7, 2012
4GQG
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CRYSTAL STRUCTURE OF AKR1B10 COMPLEXED WITH NADP+
Descriptor:Aldo-keto reductase family 1 member B10, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Zhang, L., Zheng, X., Chen, S., Zhai, J., Hu, X.
Deposit date:2012-08-23
Release date:2013-08-28
Last modified:2013-12-11
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Inhibitor selectivity between aldo-keto reductase superfamily members AKR1B10 and AKR1B1: Role of Trp112 (Trp111)
Febs Lett., 587, 2013