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Human Cytochrome P450 3A5 (CYP3A5)
Descriptor:	Cytochrome P450 3A5, PROTOPORPHYRIN IX CONTAINING FE, RITONAVIR
Authors:	Hsu, M.-H, Johnson, E.F.
Deposit date:	2017-04-05
Release date:	2017-11-15
Last modified:	2023-10-04
Method:	X-RAY DIFFRACTION (2.91 Å)
Cite:	The X-Ray Crystal Structure of the Human Mono-Oxygenase Cytochrome P450 3A5-Ritonavir Complex Reveals Active Site Differences between P450s 3A4 and 3A5. Mol. Pharmacol., 93, 2018

Effects of the E310A Mutation of Cytochrome P450 4B1 (CYP4B1) on n-Octane binding and Heme Ruffling
Descriptor:	Cytochrome P450 4B1, N-OCTANE, PROTOPORPHYRIN IX CONTAINING FE
Authors:	Hsu, M.-H, Johnson, E.F.
Deposit date:	2018-01-25
Release date:	2018-06-20
Last modified:	2023-10-04
Method:	X-RAY DIFFRACTION (2.674 Å)
Cite:	Noncovalent interactions dominate dynamic heme distortion in cytochrome P450 4B1. J. Biol. Chem., 293, 2018

Structure Of Cytochrome P450 4B1 (CYP4B1) Complexed with the Inhibitor HET0016
Descriptor:	Cytochrome P450 4B1, N-(4-butyl-2-methylphenyl)-N'-hydroxyimidoformamide, PROTOPORPHYRIN IX CONTAINING FE
Authors:	Hsu, M.-H, Johnson, E.F.
Deposit date:	2018-01-25
Release date:	2018-06-20
Last modified:	2023-10-04
Method:	X-RAY DIFFRACTION (2.72 Å)
Cite:	Noncovalent interactions dominate dynamic heme distortion in cytochrome P450 4B1. J. Biol. Chem., 293, 2018

Cytochrome P450 (CYP) 2C9 TCA007 Inhibitor Complex
Descriptor:	Cytochrome P450 2C9, GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:	Johnson, E.F, Hsu, M.-H.
Deposit date:	2017-05-30
Release date:	2017-09-13
Last modified:	2023-10-04
Method:	X-RAY DIFFRACTION (2.001 Å)
Cite:	Determinants of the Inhibition of DprE1 and CYP2C9 by Antitubercular Thiophenes. Angew. Chem. Int. Ed. Engl., 56, 2017