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7ZAY
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BU of 7zay by Molmil
Human heparan sulfate polymerase complex EXT1-EXT2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Exostosin-1, Exostosin-2, ...
Authors:Leisico, F, Omeiri, J, Hons, M, Schoehn, G, Lortat-Jacob, H, Wild, R.
Deposit date:2022-03-23
Release date:2022-12-07
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structure of the human heparan sulfate polymerase complex EXT1-EXT2.
Nat Commun, 13, 2022
6ZG0
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BU of 6zg0 by Molmil
SARM1 SAM1-2 domains
Descriptor: 1,2-ETHANEDIOL, BETA-MERCAPTOETHANOL, DI(HYDROXYETHYL)ETHER, ...
Authors:Sporny, M, Guez-Haddad, J, Khazma, T, Yaron, A, Dessau, M, Mim, C, Isupov, M.N, Zalk, R, Hons, M, Opatowsky, Y.
Deposit date:2020-06-18
Release date:2020-11-11
Last modified:2020-12-09
Method:ELECTRON MICROSCOPY (7.7 Å)
Cite:Structural basis for SARM1 inhibition and activation under energetic stress.
Elife, 9, 2020
6ZFX
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BU of 6zfx by Molmil
hSARM1 GraFix-ed
Descriptor: (~{E})-4-methylnon-4-enedial, NAD(+) hydrolase SARM1
Authors:Sporny, M, Guez-Haddad, J, Khazma, T, Yaron, A, Dessau, M, Mim, C, Isupov, M.N, Zalk, R, Hons, M, Opatowsky, Y.
Deposit date:2020-06-18
Release date:2020-11-18
Last modified:2022-11-09
Method:ELECTRON MICROSCOPY (2.88 Å)
Cite:Structural basis for SARM1 inhibition and activation under energetic stress.
Elife, 9, 2020
6ZG1
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BU of 6zg1 by Molmil
SARM1 SAM1-2 domains
Descriptor: 1,2-ETHANEDIOL, BETA-MERCAPTOETHANOL, DI(HYDROXYETHYL)ETHER, ...
Authors:Sporny, M, Guez-Haddad, J, Khazma, T, Yaron, A, Dessau, M, Mim, C, Isupov, M.N, Zalk, R, Hons, M, Opatowsky, Y.
Deposit date:2020-06-18
Release date:2020-11-11
Last modified:2020-12-09
Method:ELECTRON MICROSCOPY (3.77 Å)
Cite:Structural basis for SARM1 inhibition and activation under energetic stress.
Elife, 9, 2020
7ANW
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BU of 7anw by Molmil
hSARM1 NAD+ complex
Descriptor: NAD(+) hydrolase SARM1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Sporny, M, Guez-Haddad, J, Khazma, T, Yaron, A, Mim, C, Isupov, M.N, Zalk, R, Dessau, M, Hons, M, Opatowsky, Y.
Deposit date:2020-10-13
Release date:2020-11-11
Last modified:2020-12-09
Method:ELECTRON MICROSCOPY (2.68 Å)
Cite:Structural basis for SARM1 inhibition and activation under energetic stress.
Elife, 9, 2020
6GGS
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BU of 6ggs by Molmil
Structure of RIP2 CARD filament
Descriptor: Receptor-interacting serine/threonine-protein kinase 2
Authors:Pellegrini, E, Cusack, S, Desfosses, A, Schoehn, G, Malet, H, Gutsche, I, Sachse, C, Hons, M.
Deposit date:2018-05-03
Release date:2018-10-17
Method:ELECTRON MICROSCOPY (3.94 Å)
Cite:RIP2 filament formation is required for NOD2 dependent NF-kappa B signalling.
Nat Commun, 9, 2018
8AOW
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BU of 8aow by Molmil
CryoEM structure of the Chikungunya virus nsP1 capping pores in complex with m7GTP and SAH ligands
Descriptor: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, S-ADENOSYL-L-HOMOCYSTEINE, ...
Authors:Jones, R, Hons, M, Reguera, J.
Deposit date:2022-08-08
Release date:2023-03-29
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Structural basis and dynamics of Chikungunya alphavirus RNA capping by nsP1 capping pores.
Proc.Natl.Acad.Sci.USA, 120, 2023
8AOX
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BU of 8aox by Molmil
CryoEM structure of the Chikungunya virus nsP1 capping pores in complex with SAM
Descriptor: S-ADENOSYLMETHIONINE, ZINC ION, mRNA-capping enzyme nsP1
Authors:Jones, R, Hons, M, Reguera, J.
Deposit date:2022-08-08
Release date:2023-03-29
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structural basis and dynamics of Chikungunya alphavirus RNA capping by nsP1 capping pores.
Proc.Natl.Acad.Sci.USA, 120, 2023
8AXV
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BU of 8axv by Molmil
Structure of an open form of CHIKV nsP1 capping pores
Descriptor: 2-amino-7-methyl-1,7-dihydro-6H-purin-6-one, ZINC ION, mRNA-capping enzyme nsP1
Authors:Reguera, J, Jones, R, Hons, M.
Deposit date:2022-09-01
Release date:2023-03-29
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structural basis and dynamics of Chikungunya alphavirus RNA capping by nsP1 capping pores.
Proc.Natl.Acad.Sci.USA, 120, 2023
8APX
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BU of 8apx by Molmil
CryoEM structure of the Chikungunya virus nsP1 capping pores in covalent complex with a 7GMP cap structure
Descriptor: Polyprotein P1234, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION
Authors:Jones, R, Hons, M, Reguera, J.
Deposit date:2022-08-10
Release date:2023-05-03
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural basis and dynamics of Chikungunya alphavirus RNA capping by nsP1 capping pores.
Proc.Natl.Acad.Sci.USA, 120, 2023
8AOV
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BU of 8aov by Molmil
CryoEM structure of the Chikungunya virus nsP1 capping pores in complex with GTP
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, ZINC ION, mRNA-capping enzyme nsP1
Authors:Jones, R, Hons, M, Reguera, J.
Deposit date:2022-08-08
Release date:2023-05-31
Method:ELECTRON MICROSCOPY (2.48 Å)
Cite:Structural basis and dynamics of Chikungunya alphavirus RNA capping by nsP1 capping pores.
Proc.Natl.Acad.Sci.USA, 120, 2023
7QG0
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BU of 7qg0 by Molmil
Inhibitor-induced hSARM1 duplex
Descriptor: NAD(+) hydrolase SARM1
Authors:Zalk, R, Kahzma, T, Guez-Haddad, J.
Deposit date:2021-12-07
Release date:2022-12-21
Last modified:2023-01-11
Method:ELECTRON MICROSCOPY (4.02 Å)
Cite:A duplex structure of SARM1 octamers stabilized by a new inhibitor.
Cell.Mol.Life Sci., 80, 2022
6RLP
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BU of 6rlp by Molmil
Cryo-EM reconstruction of TMV coat protein
Descriptor: Capsid protein, RNA (5'-R(P*GP*AP*A)-3')
Authors:Kandiah, E, Effantin, G.
Deposit date:2019-05-02
Release date:2022-11-23
Method:ELECTRON MICROSCOPY (2.3 Å)
Cite:Cryo-EM reconstruction of TMV coat protein
To Be Published
8P2M
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BU of 8p2m by Molmil
C. elegans TIR-1 protein.
Descriptor: NAD(+) hydrolase tir-1
Authors:Isupov, M.N, Opatowsky, Y.
Deposit date:2023-05-16
Release date:2023-09-06
Method:ELECTRON MICROSCOPY (3.82 Å)
Cite:Structure-function analysis of ceTIR-1/hSARM1 explains the lack of Wallerian axonal degeneration in C. elegans.
Cell Rep, 42, 2023
8P2L
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BU of 8p2l by Molmil
A CHIMERA construct containing human SARM1 ARM and SAM domains and C. elegans TIR domain.
Descriptor: NAD(+) hydrolase SARM1,NAD(+) hydrolase tir-1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Isupov, M.N, Opatowsky, Y.
Deposit date:2023-05-16
Release date:2023-09-06
Method:ELECTRON MICROSCOPY (2.68 Å)
Cite:Structure-function analysis of ceTIR-1/hSARM1 explains the lack of Wallerian axonal degeneration in C. elegans.
Cell Rep, 42, 2023
8AZA
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BU of 8aza by Molmil
Structure of RIP2K dimer bound to the XIAP BIR2 domain
Descriptor: E3 ubiquitin-protein ligase XIAP, Receptor-interacting serine/threonine-protein kinase 2, ZINC ION
Authors:Pellegrini, E, Cusack, S.
Deposit date:2022-09-05
Release date:2022-10-26
Last modified:2023-09-20
Method:ELECTRON MICROSCOPY (3.15 Å)
Cite:Structure shows that the BIR2 domain of E3 ligase XIAP binds across the RIPK2 kinase dimer interface.
Life Sci Alliance, 6, 2023
8QHC
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BU of 8qhc by Molmil
Cryo-EM structure of SidH from Legionella pneumophila in complex with LubX
Descriptor: E3 ubiquitin--protein ligase, Elongation factor Tu, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Sharma, R, Adams, M, Bhogaraju, S.
Deposit date:2023-09-07
Release date:2023-10-11
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis for the toxicity of Legionella pneumophila effector SidH.
Nat Commun, 14, 2023
8QFS
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BU of 8qfs by Molmil
Cryo-EM structure of SidH from Legionella pneumophila
Descriptor: Elongation factor Tu, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Sharma, R, Weis, F, Bhogaraju, S.
Deposit date:2023-09-04
Release date:2023-10-11
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Structural basis for the toxicity of Legionella pneumophila effector SidH.
Nat Commun, 14, 2023
6GFJ
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BU of 6gfj by Molmil
Structure of RIP2 CARD domain fused to crystallisable MBP tag
Descriptor: Sugar ABC transporter substrate-binding protein,Receptor-interacting serine/threonine-protein kinase 2, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
Authors:Pellegrini, E, Cusack, S.
Deposit date:2018-04-30
Release date:2019-03-13
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:RIP2 filament formation is required for NOD2 dependent NF-kappa B signalling.
Nat Commun, 9, 2018

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PDB entries from 2024-03-27

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