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4BSZ
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BU of 4bsz by Molmil
Crystal Structure of the Yeast Ribosomal Protein Rps3 in Complex with its Chaperone Yar1
Descriptor: 40S RIBOSOMAL PROTEIN S3, ANKYRIN REPEAT-CONTAINING PROTEIN YAR1
Authors:Holzer, S, Ban, N, Klinge, S.
Deposit date:2013-06-12
Release date:2013-09-04
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.842 Å)
Cite:Crystal Structure of the Yeast Ribosomal Protein Rps3 in Complex with its Chaperone Yar1
J.Mol.Biol., 425, 2013
5MQI
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BU of 5mqi by Molmil
Crystal structure of the N-terminal domain of human Timeless
Descriptor: Protein timeless homolog,Protein timeless homolog, SULFATE ION
Authors:Holzer, S, Kilkenny, M.L, Pellegrini, L.
Deposit date:2016-12-20
Release date:2017-03-08
Last modified:2017-05-31
Method:X-RAY DIFFRACTION (1.847 Å)
Cite:Crystal structure of the N-terminal domain of human Timeless and its interaction with Tipin.
Nucleic Acids Res., 45, 2017
5OFN
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BU of 5ofn by Molmil
Crystal structure of the heterotrimeric PriSLX primase from S. solfataricus.
Descriptor: DNA primase large subunit PriL,PriL-X fusion protein, DNA primase small subunit PriS, ZINC ION
Authors:Pellegrini, L, Holzer, S.
Deposit date:2017-07-11
Release date:2017-11-29
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.005 Å)
Cite:Primer synthesis by a eukaryotic-like archaeal primase is independent of its Fe-S cluster.
Nat Commun, 8, 2017
5OF3
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BU of 5of3 by Molmil
Crystal structure of the heterotrimeric PriSLX primase from S. solfataricus.
Descriptor: DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, DNA primase large subunit PriL, DNA primase small subunit PriS, ...
Authors:Pellegrini, L, Holzer, S.
Deposit date:2017-07-10
Release date:2017-11-29
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.906 Å)
Cite:Primer synthesis by a eukaryotic-like archaeal primase is independent of its Fe-S cluster.
Nat Commun, 8, 2017
6TAZ
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BU of 6taz by Molmil
Timeless couples G quadruplex detection with processing by DDX11 during DNA replication
Descriptor: Protein timeless homolog
Authors:Lerner Koch, L, Holzer, S, Kilkenny, M.L, Murat, P, Svikovic, S, Schiavone, D, Bittleston, A, Maman, J.D, Branzei, D, Stott, K, Pellegrini, L, Sale, E.J.
Deposit date:2019-10-31
Release date:2020-07-01
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Timeless couples G-quadruplex detection with processing by DDX11 helicase during DNA replication.
Embo J., 39, 2020
6T9Q
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BU of 6t9q by Molmil
Crystal structure of the second, C-terminal repeat of the DNA-binding domain of human TImeless
Descriptor: Protein timeless homolog
Authors:Pellegrini, L, Holzer, S.
Deposit date:2019-10-28
Release date:2020-07-01
Last modified:2020-12-16
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Timeless couples G-quadruplex detection with processing by DDX11 helicase during DNA replication.
Embo J., 39, 2020
6R4S
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BU of 6r4s by Molmil
Crystal structure of the Pri1 subunit of human primase bound to ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, DNA primase small subunit, MANGANESE (II) ION, ...
Authors:Kilkenny, M.L, Pellegrini, L.
Deposit date:2019-03-24
Release date:2019-09-11
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structural Basis for Inhibition of Human Primase by Arabinofuranosyl Nucleoside Analogues Fludarabine and Vidarabine.
Acs Chem.Biol., 14, 2019
6R4T
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BU of 6r4t by Molmil
Crystal structure of the Pri1 subunit of human primase bound to vidarabine triphosphate
Descriptor: 1,2-ETHANEDIOL, 9-{5-O-[(S)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-beta-D-arabinofuranosyl}-9H-purin-6-amine, DNA primase small subunit, ...
Authors:Kilkenny, M.L, Pellegrini, L.
Deposit date:2019-03-24
Release date:2019-09-11
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural Basis for Inhibition of Human Primase by Arabinofuranosyl Nucleoside Analogues Fludarabine and Vidarabine.
Acs Chem.Biol., 14, 2019
6R5E
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BU of 6r5e by Molmil
Crystal structure of the Pri1 subunit of human primase bound to 2F-ATP
Descriptor: 1,2-ETHANEDIOL, 2-fluoro-ATP, DNA primase small subunit, ...
Authors:Kilkenny, M.L, Pellegrini, L.
Deposit date:2019-03-24
Release date:2019-09-11
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural Basis for Inhibition of Human Primase by Arabinofuranosyl Nucleoside Analogues Fludarabine and Vidarabine.
Acs Chem.Biol., 14, 2019
6RB4
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BU of 6rb4 by Molmil
Crystal structure of the Pri1 subunit of human primase
Descriptor: 1,2-ETHANEDIOL, DNA primase small subunit, ZINC ION
Authors:Kilkenny, M.L, Pellegrini, L.
Deposit date:2019-04-09
Release date:2019-09-11
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural Basis for Inhibition of Human Primase by Arabinofuranosyl Nucleoside Analogues Fludarabine and Vidarabine.
Acs Chem.Biol., 14, 2019
6R5D
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BU of 6r5d by Molmil
Crystal structure of the Pri1 subunit of human primase bound to dATP
Descriptor: 1,2-ETHANEDIOL, 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA primase small subunit, ...
Authors:Kilkenny, M.L, Pellegrini, L.
Deposit date:2019-03-24
Release date:2019-09-11
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural Basis for Inhibition of Human Primase by Arabinofuranosyl Nucleoside Analogues Fludarabine and Vidarabine.
Acs Chem.Biol., 14, 2019
6R4U
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BU of 6r4u by Molmil
Crystal structure of the Pri1 subunit of human primase bound to fludarabine triphosphate
Descriptor: 1,2-ETHANEDIOL, 2-fluoro-9-{5-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-beta-D-arabinofuranosyl}-9H-purin-6-a mine, DNA primase small subunit, ...
Authors:Kilkenny, M.L, Pellegrini, L.
Deposit date:2019-03-24
Release date:2019-09-11
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Basis for Inhibition of Human Primase by Arabinofuranosyl Nucleoside Analogues Fludarabine and Vidarabine.
Acs Chem.Biol., 14, 2019
5OGS
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BU of 5ogs by Molmil
Crystal structure of human AND-1 SepB domain
Descriptor: MALONATE ION, WD repeat and HMG-box DNA-binding protein 1
Authors:Pellegrini, L, Simon, A.C.
Deposit date:2017-07-13
Release date:2017-11-29
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.503 Å)
Cite:The human CTF4-orthologue AND-1 interacts with DNA polymerase alpha /primase via its unique C-terminal HMG box.
Open Biol, 7, 2017

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