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1Y4K
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BU of 1y4k by Molmil
Lipoxygenase-1 (Soybean) at 100K, N694G Mutant
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, FE (II) ION, ...
Authors:Chruszcz, M, Segraves, E, Holman, T.R, Minor, W.
Deposit date:2004-12-01
Release date:2005-12-13
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Kinetic, spectroscopic, and structural investigations of the soybean lipoxygenase-1 first-coordination sphere mutant, Asn694Gly.
Biochemistry, 45, 2006
1FGM
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BU of 1fgm by Molmil
LIPOXYGENASE-1 (SOYBEAN) AT 100K, N694H MUTANT
Descriptor: FE (III) ION, SEED LIPOXYGENASE-1
Authors:Tomchick, D.R, Minor, W, Holman, T.R.
Deposit date:2000-07-28
Release date:2001-10-24
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and functional characterization of second-coordination sphere mutants of soybean lipoxygenase-1.
Biochemistry, 40, 2001
1FGT
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BU of 1fgt by Molmil
LIPOXYGENASE-1 (SOYBEAN) AT 100K, Q697N MUTANT
Descriptor: FE (III) ION, SEED LIPOXYGENASE-1
Authors:Tomchick, D.R, Minor, W, Holman, T.
Deposit date:2000-07-28
Release date:2001-07-04
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Structural and functional characterization of second-coordination sphere mutants of soybean lipoxygenase-1.
Biochemistry, 40, 2001
1F8N
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BU of 1f8n by Molmil
LIPOXYGENASE-1 (SOYBEAN) AT 100K, NEW REFINEMENT
Descriptor: FE (II) ION, LIPOXYGENASE-1
Authors:Tomchick, D.R, Minor, W, Holman, T.
Deposit date:2000-06-30
Release date:2001-07-04
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural and functional characterization of second-coordination sphere mutants of soybean lipoxygenase-1.
Biochemistry, 40, 2001
1FGQ
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BU of 1fgq by Molmil
LIPOXYGENASE-1 (SOYBEAN) AT 100K, Q495E MUTANT
Descriptor: FE (III) ION, SEED LIPOXYGENASE-1
Authors:Tomchick, D.R, Minor, W, Holman, T.
Deposit date:2000-07-28
Release date:2001-07-04
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural and functional characterization of second-coordination sphere mutants of soybean lipoxygenase-1.
Biochemistry, 40, 2001
1FGR
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BU of 1fgr by Molmil
LIPOXYGENASE-1 (SOYBEAN) AT 100K, Q697E MUTANT
Descriptor: FE (III) ION, SEED LIPOXYGENASE-1
Authors:Tomchick, D.R, Minor, W, Holman, T.
Deposit date:2000-07-28
Release date:2001-07-04
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural and functional characterization of second-coordination sphere mutants of soybean lipoxygenase-1.
Biochemistry, 40, 2001
1FGO
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BU of 1fgo by Molmil
LIPOXYGENASE-1 (SOYBEAN) AT 100K, Q495A MUTANT
Descriptor: FE (III) ION, SEED LIPOXYGENASE-1
Authors:Tomchick, D.R, Minor, W, Holman, T.
Deposit date:2000-07-28
Release date:2001-07-04
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Structural and functional characterization of second-coordination sphere mutants of soybean lipoxygenase-1.
Biochemistry, 40, 2001
8GHB
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BU of 8ghb by Molmil
The structure of h12-LOX in monomeric form
Descriptor: FE (II) ION, Polyunsaturated fatty acid lipoxygenase ALOX12
Authors:Black, K.A, Mobbs, J.I, Venugopal, H, Thal, D.M, Glukhova, A.
Deposit date:2023-03-09
Release date:2023-08-09
Last modified:2023-10-11
Method:ELECTRON MICROSCOPY (2.76 Å)
Cite:Cryo-EM structures of human arachidonate 12S-lipoxygenase bound to endogenous and exogenous inhibitors.
Blood, 142, 2023
8GHE
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BU of 8ghe by Molmil
The structure of h12-LOX in tetrameric form bound to endogenous inhibitor oleoyl-CoA
Descriptor: FE (II) ION, Polyunsaturated fatty acid lipoxygenase ALOX12, S-{(3R,5R,9R)-1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-3,5,9-trihydroxy-8,8-dimethyl-3,5-dioxido-10,14-dioxo-2,4,6-trioxa-11,15-diaza-3lambda~5~,5lambda~5~-diphosphaheptadecan-17-yl} (9Z)-octadec-9-enethioate (non-preferred name)
Authors:Black, K.A, Mobbs, J.I, Venugopal, H, Thal, D.M, Glukhova, A.
Deposit date:2023-03-09
Release date:2023-08-09
Last modified:2023-10-11
Method:ELECTRON MICROSCOPY (2.05 Å)
Cite:Cryo-EM structures of human arachidonate 12S-lipoxygenase bound to endogenous and exogenous inhibitors.
Blood, 142, 2023
8GHC
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BU of 8ghc by Molmil
The structure of h12-LOX in dimeric form
Descriptor: FE (II) ION, Polyunsaturated fatty acid lipoxygenase ALOX12
Authors:Black, K.A, Mobbs, J.I, Venugopal, H, Thal, D.M, Glukhova, A.
Deposit date:2023-03-09
Release date:2023-08-09
Last modified:2023-10-11
Method:ELECTRON MICROSCOPY (2.3 Å)
Cite:Cryo-EM structures of human arachidonate 12S-lipoxygenase bound to endogenous and exogenous inhibitors.
Blood, 142, 2023
8GHD
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BU of 8ghd by Molmil
The structure of h12-LOX in hexameric form bound to inhibitor ML355 and arachidonic acid
Descriptor: ARACHIDONIC ACID, FE (II) ION, N-(1,3-benzothiazol-2-yl)-4-{[(2-hydroxy-3-methoxyphenyl)methyl]amino}benzene-1-sulfonamide, ...
Authors:Black, K.A, Mobbs, J.I, Venugopal, H, Thal, D.M, Glukhova, A.
Deposit date:2023-03-09
Release date:2023-08-09
Last modified:2023-10-11
Method:ELECTRON MICROSCOPY (2.2 Å)
Cite:Cryo-EM structures of human arachidonate 12S-lipoxygenase bound to endogenous and exogenous inhibitors.
Blood, 142, 2023
7LAF
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BU of 7laf by Molmil
15-lipoxygenase-2 loop mutant bound to imidazole-based inhibitor
Descriptor: 3-{[(4-methylphenyl)methyl]sulfanyl}-1-phenyl-1H-1,2,4-triazole, MANGANESE (II) ION, Polyunsaturated fatty acid lipoxygenase ALOX15B
Authors:Newcomer, M.E, Gilbert, N.C, Neau, D.B.
Deposit date:2021-01-06
Release date:2022-01-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.44 Å)
Cite:Kinetic and structural investigations of novel inhibitors of human epithelial 15-lipoxygenase-2.
Bioorg.Med.Chem., 46, 2021

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