Author results

1CF1
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ARRESTIN FROM BOVINE ROD OUTER SEGMENTS
Descriptor:PROTEIN (ARRESTIN)
Authors:Hirsch, J.A., Schubert, C., Gurevich, V.V., Sigler, P.B.
Deposit date:1999-03-23
Release date:1999-04-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The 2.8 A crystal structure of visual arrestin: a model for arrestin's regulation.
Cell(Cambridge,Mass.), 97, 1999
1JGG
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EVEN-SKIPPED HOMEODOMAIN COMPLEXED TO AT-RICH DNA
Descriptor:5'-D(P*TP*AP*AP*TP*TP*GP*AP*AP*TP*T)-3', 5'-D(P*AP*AP*TP*TP*CP*AP*AP*TP*TP*A)-3', Segmentation Protein Even-Skipped
Authors:Hirsch, J.A., Aggarwal, A.K.
Deposit date:2001-06-25
Release date:2001-07-06
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of the even-skipped homeodomain complexed to AT-rich DNA: new perspectives on homeodomain specificity.
EMBO J., 14, 1995
1T3L
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STRUCTURAL ANALYSIS OF THE VOLTAGE-DEPENDENT CALCIUM CHANNEL BETA SUBUNIT FUNCTIONAL CORE IN COMPLEX WITH ALPHA1 INTERACTION DOMAIN
Descriptor:Dihydropyridine-sensitive L-type, calcium channel beta-2 subunit, Voltage-dependent L-type calcium channel alpha-1S subunit
Authors:Opatowsky, Y., Chen, C.-C., Campbell, K.P., Hirsch, J.A.
Deposit date:2004-04-27
Release date:2004-05-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Analysis of Voltage-Dependent Calcium Channel Beta Subunit Functional Core and Its Complex with the Alpha1 Interaction Domain
NEURON, 42, 2004
1T3S
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STRUCTURAL ANALYSIS OF THE VOLTAGE-DEPENDENT CALCIUM CHANNEL BETA SUBUNIT FUNCTIONAL CORE
Descriptor:Dihydropyridine-sensitive L-type, calcium channel beta-2 subunit, MERCURY (II) ION
Authors:Opatowsky, Y., Chen, C.-C., Campbell, K.P., Hirsch, J.A.
Deposit date:2004-04-27
Release date:2004-05-25
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural analysis of the voltage-dependent calcium channel beta subunit functional core and its complex with the alpha 1 interaction domain.
Neuron, 42, 2004
3CHM
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CRYSTAL STRUCTURE OF PCI DOMAIN FROM A. THALIANA COP9 SIGNALOSOME SUBUNIT 7 (CSN7)
Descriptor:COP9 signalosome complex subunit 7, MAGNESIUM ION, ACETATE ION
Authors:Dessau, M., Hirsch, J.A.
Deposit date:2008-03-10
Release date:2008-10-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The Arabidopsis COP9 signalosome subunit 7 is a model PCI domain protein with subdomains involved in COP9 signalosome assembly
Plant Cell, 20, 2008
2HT6
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CRYSTAL STRUCTURE OF HUMAN GEM G-DOMAIN BOUND TO GDP
Descriptor:GTP-binding protein GEM, MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE
Authors:Opatowsky, Y., Hirsch, J.A.
Deposit date:2006-07-25
Release date:2006-10-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure-function studies of the G-domain from human gem, a novel small G-protein.
Febs Lett., 580, 2006
3BJ4
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THE KCNQ1 (KV7.1) C-TERMINUS, A MULTI-TIERED SCAFFOLD FOR SUBUNIT ASSEMBLY AND PROTEIN INTERACTION
Descriptor:Potassium voltage-gated channel subfamily KQT member 1, NICKEL (II) ION
Authors:Wiener, R., Hirsch, J.A.
Deposit date:2007-12-03
Release date:2008-01-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The KCNQ1 (Kv7.1) COOH terminus, a multitiered scaffold for subunit assembly and protein interaction.
J.Biol.Chem., 283, 2008
3Q72
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CRYSTAL STRUCTURE OF RAD G-DOMAIN-GTP ANALOG COMPLEX
Descriptor:GTP-binding protein RAD, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, MAGNESIUM ION, ...
Authors:Sasson, Y., Navon-Perry, L., Hirsch, J.A.
Deposit date:2011-01-04
Release date:2011-09-21
Last modified:2011-10-26
Method:X-RAY DIFFRACTION (1.655 Å)
Cite:RGK Family G-Domain:GTP Analog Complex Structures and Nucleotide-Binding Properties.
J.Mol.Biol., 413, 2011
3Q7P
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CRYSTAL STRUCTURE OF RAD G-DOMAIN-GTP ANALOG COMPLEX
Descriptor:GTP-binding protein RAD, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, MAGNESIUM ION
Authors:Sasson, Y., Navon-Perry, L., Hirsch, J.A.
Deposit date:2011-01-05
Release date:2011-09-21
Last modified:2011-10-26
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:RGK Family G-Domain:GTP Analog Complex Structures and Nucleotide-Binding Properties.
J.Mol.Biol., 413, 2011
3Q7Q
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CRYSTAL STRUCTURE OF RAD G-DOMAIN Q148A-GTP ANALOG COMPLEX
Descriptor:GTP-binding protein RAD, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, MAGNESIUM ION, ...
Authors:Sasson, Y., Navon-Perry, L., Hirsch, J.A.
Deposit date:2011-01-05
Release date:2011-09-21
Last modified:2011-10-26
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:RGK Family G-Domain:GTP Analog Complex Structures and Nucleotide-Binding Properties.
J.Mol.Biol., 413, 2011
3Q85
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CRYSTAL STRUCTURE OF REM2 G-DOMAIN -GTP ANALOG COMPLEX
Descriptor:GTP-binding protein REM 2, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, MAGNESIUM ION, ...
Authors:Navon-Perry, L., Hirsch, J.A.
Deposit date:2011-01-06
Release date:2011-09-21
Last modified:2011-10-26
Method:X-RAY DIFFRACTION (1.757 Å)
Cite:RGK Family G-Domain:GTP Analog Complex Structures and Nucleotide-Binding Properties.
J.Mol.Biol., 413, 2011
3US9
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CRYSTAL STRUCTURE OF THE NCX1 INTRACELLULAR TANDEM CALCIUM BINDING DOMAINS(CBD12)
Descriptor:Sodium/calcium exchanger 1, CALCIUM ION
Authors:Giladi, M., Sasson, Y., Hirsch, J.A., Khananshvili, D.
Deposit date:2011-11-23
Release date:2012-07-11
Last modified:2017-08-16
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:A Common Ca2+-Driven Interdomain Module Governs Eukaryotic NCX Regulation
Plos One, 7, 2012
4DEX
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CRYSTAL STRUCTURE OF THE VOLTAGE DEPENDENT CALCIUM CHANNEL BETA-2 SUBUNIT IN COMPLEX WITH THE CAV2.2 I-II LINKER.
Descriptor:Voltage-dependent L-type calcium channel subunit beta-2, Voltage-dependent N-type calcium channel subunit alpha-1B
Authors:Almagor, L., Hirsch, J.A.
Deposit date:2012-01-22
Release date:2012-06-13
Last modified:2017-08-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:The role of a voltage-dependent Ca2+ channel intracellular linker: a structure-function analysis.
J.Neurosci., 32, 2012
4DEY
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CRYSTAL STRUCTURE OF THE VOLTAGE DEPENDENT CALCIUM CHANNEL BETA-2 SUBUNIT IN COMPLEX WITH THE CAV1.2 I-II LINKER.
Descriptor:Voltage-dependent L-type calcium channel subunit alpha-1C, Voltage-dependent L-type calcium channel subunit beta-2, BROMIDE ION
Authors:Almagor, L., Hirsch, J.A.
Deposit date:2012-01-22
Release date:2012-06-13
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:The role of a voltage-dependent Ca2+ channel intracellular linker: a structure-function analysis.
J.Neurosci., 32, 2012
4GA9
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CRYSTAL STRUCTURE OF RAT GALECTIN-1 IN COMPLEX WITH LACTOSE
Descriptor:Galectin-1, ALPHA-LACTOSE
Authors:Segev, O., Hirsch, J.A.
Deposit date:2012-07-25
Release date:2013-08-07
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Gal-1 structure analysis
to be published
4LCV
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CRYSTAL STRUCTURE OF DOC2B C2A DOMAIN
Descriptor:Double C2-like domain-containing protein beta, SULFATE ION, BETA-MERCAPTOETHANOL, ...
Authors:Giladi, M., Almagor, L., Hirsch, J.A.
Deposit date:2013-06-23
Release date:2013-09-11
Last modified:2013-11-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The C2B Domain Is the Primary Ca(2+) Sensor in DOC2B: A Structural and Functional Analysis.
J.Mol.Biol., 425, 2013
4LDC
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CRYSTAL STRUCTURE OF DOC2B C2B DOMAIN
Descriptor:Double C2-like domain-containing protein beta, CALCIUM ION, CITRATE ANION
Authors:Giladi, M., Almagor, L., Hirsch, J.A.
Deposit date:2013-06-24
Release date:2013-09-11
Last modified:2013-11-13
Method:X-RAY DIFFRACTION (1.264 Å)
Cite:The C2B Domain Is the Primary Ca(2+) Sensor in DOC2B: A Structural and Functional Analysis.
J.Mol.Biol., 425, 2013
4UMO
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CRYSTAL STRUCTURE OF THE KV7.1 PROXIMAL C-TERMINAL DOMAIN IN COMPLEX WITH CALMODULIN
Descriptor:POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY KQT MEMBER 1, CALMODULIN, POTASSIUM ION, ...
Authors:Sachyani, D., Hirsch, J.A.
Deposit date:2014-05-20
Release date:2014-11-05
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural Basis of a Kv7.1 Potassium Channel Gating Module: Studies of the Intracellular C-Terminal Domain in Complex with Calmodulin
Structure, 22, 2014
4V0C
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CRYSTAL STRUCTURE OF THE KV7.1 PROXIMAL C-TERMINAL DOMAIN IN COMPLEX WITH CALMODULIN
Descriptor:POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY KQT MEMBER 1, CALMODULIN, THIOCYANATE ION, ...
Authors:Sachyani, D., Hirsch, J.A.
Deposit date:2014-09-14
Release date:2014-11-05
Last modified:2014-12-17
Method:X-RAY DIFFRACTION (2.86 Å)
Cite:Structural Basis of a Kv7.1 Potassium Channel Gating Module: Studies of the Intracellular C-Terminal Domain in Complex with Calmodulin.
Structure, 22, 2014
5J03
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CRYSTAL STRUCTURE OF A CHIMERIC KV7.2 - KV7.3 PROXIMAL C-TERMINAL DOMAIN IN COMPLEX WITH CALMODULIN
Descriptor:Potassium voltage-gated channel subfamily KQT member 3,Potassium voltage-gated channel subfamily KQT member 2, Calmodulin, CALCIUM ION, ...
Authors:Strulovich, R., Hirsch, J.A.
Deposit date:2016-03-26
Release date:2016-09-07
Last modified:2016-10-05
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Insights into the M-Channel Proximal C-Terminus/Calmodulin Complex.
Biochemistry, 55, 2016
1FOK
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STRUCTURE OF RESTRICTION ENDONUCLEASE FOKI BOUND TO DNA
Descriptor:DNA (5'-D(*TP*CP*GP*GP*AP*TP*GP*AP*TP*AP*AP*CP*GP*CP*TP*AP*G P*TP*CP*A)-3'), DNA (5'-D(*AP*TP*GP*AP*CP*TP*AP*GP*CP*GP*TP*TP*AP*TP*CP*AP*T P*CP*CP*G)-3'), PROTEIN (FOKI RESTRICTION ENDONUCLEASE)
Authors:Aggarwal, D.A., Wah, J.A., Hirsch, L.F., Dorner, I., Schildkraut, A.K.
Deposit date:1997-04-18
Release date:1997-12-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of the multimodular endonuclease FokI bound to DNA.
Nature, 388, 1997