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3DDC
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BU of 3ddc by Molmil
Crystal Structure of NORE1A in Complex with RAS
Descriptor: GTPase HRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
Authors:Stieglitz, B, Bee, C, Schwarz, D, Yildiz, O, Moshnikova, A, Khokhlatchev, A, Herrmann, C.
Deposit date:2008-06-05
Release date:2008-07-15
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Novel type of Ras effector interaction established between tumour suppressor NORE1A and Ras switch II
Embo J., 27, 2008
3BW8
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BU of 3bw8 by Molmil
Crystal structure of the Clostridium limosum C3 exoenzyme
Descriptor: Mono-ADP-ribosyltransferase C3, SULFATE ION
Authors:Vogelsgesang, M, Stieglitz, B, Herrmann, C, Pautsch, A, Aktories, K.
Deposit date:2008-01-08
Release date:2008-04-01
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of the Clostridium limosum C3 exoenzyme.
Febs Lett., 582, 2008
1I35
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BU of 1i35 by Molmil
SOLUTION STRUCTURE OF THE RAS-BINDING DOMAIN OF THE PROTEIN KINASE BYR2 FROM SCHIZOSACCHAROMYCES POMBE
Descriptor: PROTEIN KINASE BYR2
Authors:Gronwald, W, Huber, F, Grunewald, P, Sporner, M, Wohlgemuth, S, Herrmann, C, Kalbitzer, H.R.
Deposit date:2001-02-13
Release date:2001-12-12
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Solution structure of the Ras binding domain of the protein kinase Byr2 from Schizosaccharomyces pombe.
Structure, 9, 2001
1F5N
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BU of 1f5n by Molmil
HUMAN GUANYLATE BINDING PROTEIN-1 IN COMPLEX WITH THE GTP ANALOGUE, GMPPNP.
Descriptor: INTERFERON-INDUCED GUANYLATE-BINDING PROTEIN 1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
Authors:Prakash, B, Renault, L, Praefcke, G.J.K, Herrmann, C, Wittinghofer, A.
Deposit date:2000-06-15
Release date:2000-09-27
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Triphosphate structure of guanylate-binding protein 1 and implications for nucleotide binding and GTPase mechanism.
EMBO J., 19, 2000
2YMY
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BU of 2ymy by Molmil
Structure of the murine Nore1-Sarah domain
Descriptor: CADMIUM ION, RAS ASSOCIATION DOMAIN-CONTAINING PROTEIN 5
Authors:Makbul, C, Schwarz, D, Aruxandei, D.C, Wolf, E, Hofmann, E, Herrmann, C.
Deposit date:2012-10-10
Release date:2013-03-20
Last modified:2014-04-16
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Structural and Thermodynamic Characterization of Nore1-Sarah: A Small, Helical Module Important in Signal Transduction Networks.
Biochemistry, 52, 2013
1DG3
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BU of 1dg3 by Molmil
STRUCTURE OF HUMAN GUANYLATE BINDING PROTEIN-1 IN NUCLEOTIDE FREE FORM
Descriptor: PROTEIN (INTERFERON-INDUCED GUANYLATE-BINDING PROTEIN 1)
Authors:Prakash, B, Praefcke, G.J.K, Renault, L, Wittinghofer, A, Herrmann, C.
Deposit date:1999-11-23
Release date:2000-10-11
Last modified:2022-12-21
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of human guanylate-binding protein 1 representing a unique class of GTP-binding proteins.
Nature, 403, 2000
2B8W
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BU of 2b8w by Molmil
Crystal-structure of the N-terminal Large GTPase Domain of human Guanylate Binding protein 1 (hGBP1) in complex with GMP/AlF4
Descriptor: GUANOSINE-5'-MONOPHOSPHATE, Interferon-induced guanylate-binding protein 1, MAGNESIUM ION, ...
Authors:Ghosh, A, Praefcke, G.J.K, Renault, L, Wittinghofer, A, Herrmann, C.
Deposit date:2005-10-10
Release date:2006-03-07
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:How guanylate-binding proteins achieve assembly-stimulated processive cleavage of GTP to GMP.
Nature, 440, 2006
2B92
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BU of 2b92 by Molmil
Crystal-structure of the N-terminal Large GTPase Domain of human Guanylate Binding protein 1 (hGBP1) in complex with GDP/AlF3
Descriptor: ALUMINUM FLUORIDE, GUANOSINE-5'-DIPHOSPHATE, Interferon-induced guanylate-binding protein 1, ...
Authors:Ghosh, A, Praefcke, G.J.K, Renault, L, Wittinghofer, A, Herrmann, C.
Deposit date:2005-10-10
Release date:2006-03-07
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:How guanylate-binding proteins achieve assembly-stimulated processive cleavage of GTP to GMP.
Nature, 440, 2006
2BC9
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BU of 2bc9 by Molmil
Crystal-structure of the N-terminal large GTPase Domain of human Guanylate Binding protein 1 (hGBP1) in complex with non-hydrolysable GTP analogue GppNHp
Descriptor: Interferon-induced guanylate-binding protein 1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
Authors:Ghosh, A, Praefcke, G.J.K, Renault, L, Wittinghofer, A, Herrmann, C.
Deposit date:2005-10-19
Release date:2006-03-07
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:How guanylate-binding proteins achieve assembly-stimulated processive cleavage of GTP to GMP.
Nature, 440, 2006
2D4H
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BU of 2d4h by Molmil
Crystal-structure of the N-terminal large GTPase Domain of human Guanylate Binding protein 1 (hGBP1) in complex with GMP
Descriptor: GUANOSINE-5'-MONOPHOSPHATE, Interferon-induced guanylate-binding protein 1
Authors:Ghosh, A, Praefcke, G.J.K, Renault, L, Wittinghofer, A, Herrmann, C.
Deposit date:2005-10-19
Release date:2006-03-07
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:How guanylate-binding proteins achieve assembly-stimulated processive cleavage of GTP to GMP.
Nature, 440, 2006
2WJJ
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BU of 2wjj by Molmil
Structure and function of the FeoB G-domain from Methanococcus jannaschii
Descriptor: FERROUS IRON TRANSPORT PROTEIN B HOMOLOG, GUANOSINE-5'-DIPHOSPHATE
Authors:Koester, S, Wehner, M, Herrmann, C, Kuehlbrandt, W, Yildiz, O.
Deposit date:2009-05-26
Release date:2009-07-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.405 Å)
Cite:Structure and Function of the Feob G-Domain from Methanococcus Jannaschii
J.Mol.Biol., 392, 2009
2WJG
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BU of 2wjg by Molmil
Structure and function of the FeoB G-domain from Methanococcus jannaschii
Descriptor: FERROUS IRON TRANSPORT PROTEIN B HOMOLOG, GUANOSINE-5'-DIPHOSPHATE, POLYALANINE
Authors:Koester, S, Wehner, M, Herrmann, C, Kuehlbrandt, W, Yildiz, O.
Deposit date:2009-05-26
Release date:2009-07-28
Last modified:2019-10-09
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure and Function of the Feob G-Domain from Methanococcus Jannaschii.
J.Mol.Biol., 392, 2009
2WJH
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BU of 2wjh by Molmil
Structure and function of the FeoB G-domain from Methanococcus jannaschii
Descriptor: CITRATE ANION, FERROUS IRON TRANSPORT PROTEIN B HOMOLOG, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Koester, S, Wehner, M, Herrmann, C, Kuehlbrandt, W, Yildiz, O.
Deposit date:2009-05-26
Release date:2009-07-28
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure and Function of the Feob G-Domain from Methanococcus Jannaschii
J.Mol.Biol., 392, 2009
2WJI
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BU of 2wji by Molmil
Structure and function of the FeoB G-domain from Methanococcus jannaschii
Descriptor: FERROUS IRON TRANSPORT PROTEIN B HOMOLOG, MAGNESIUM ION, PHOSPHATE ION, ...
Authors:Koester, S, Wehner, M, Herrmann, C, Kuehlbrandt, W, Yildiz, O.
Deposit date:2009-05-26
Release date:2009-07-28
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.903 Å)
Cite:Structure and Function of the Feob G-Domain from Methanococcus Jannaschii
J.Mol.Biol., 392, 2009
2B3A
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BU of 2b3a by Molmil
Solution structure of the Ras-binding domain of the Ral Guanosine Dissociation Stimulator
Descriptor: Ral guanine nucleotide dissociation stimulator
Authors:Gronwald, W, Maurer, T, Fuechsl, R, Wohlgemuth, S, Herrmann, C, Kalbitzer, H.R.
Deposit date:2005-09-20
Release date:2006-09-26
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:New insights into binding of the possible cancer target RalGDS
To be Published
8R1A
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BU of 8r1a by Molmil
Model of the membrane-bound GBP1 oligomer
Descriptor: ALUMINUM FLUORIDE, GUANOSINE-5'-DIPHOSPHATE, Guanylate binding protein 1, ...
Authors:Weismehl, M, Chu, X, Kutsch, M, Lauterjung, P, Herrmann, C, Kudryashev, M, Daumke, O.
Deposit date:2023-11-01
Release date:2024-01-17
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (26.799999 Å)
Cite:Structural insights into the activation mechanism of antimicrobial GBP1.
Embo J., 43, 2024
3KUD
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BU of 3kud by Molmil
Complex of Ras-GDP with RafRBD(A85K)
Descriptor: GTPase HRas, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Filchtinski, D, Sharabi, O, Rueppel, A, Vetter, I.R, Herrmann, C, Shifman, J.M.
Deposit date:2009-11-27
Release date:2010-03-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:What makes Ras an efficient molecular switch: a computational, biophysical, and structural study of Ras-GDP interactions with mutants of Raf.
J.Mol.Biol., 399, 2010
3KUC
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BU of 3kuc by Molmil
Complex of Rap1A(E30D/K31E)GDP with RafRBD(A85K/N71R)
Descriptor: CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Filchtinski, D, Sharabi, O, Rueppel, A, Vetter, I.R, Herrmann, C, Shifman, J.M.
Deposit date:2009-11-27
Release date:2010-03-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:What makes Ras an efficient molecular switch: a computational, biophysical, and structural study of Ras-GDP interactions with mutants of Raf.
J.Mol.Biol., 399, 2010
3L8Y
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BU of 3l8y by Molmil
Complex of Ras with cyclen
Descriptor: 1,4,7,10-tetraazacyclododecane, CALCIUM ION, GTPase HRas, ...
Authors:Rosnizeck, I.C, Graf, T, Spoerner, M, Traenkle, J, Filchtinski, D, Herrmann, C, Gremer, L, Vetter, I.R, Wittinghofer, A, Koenig, B, Kalbitzer, H.R.
Deposit date:2010-01-04
Release date:2011-01-05
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Stabilizing a weak binding state for effectors in the human ras protein by cyclen complexes
Angew.Chem.Int.Ed.Engl., 49, 2010
3L8Z
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BU of 3l8z by Molmil
H-Ras wildtype new crystal form
Descriptor: CALCIUM ION, GTPase HRas, MAGNESIUM ION, ...
Authors:Rosnizeck, I.C, Graf, T, Spoerner, M, Traenkle, J, Filchtinski, D, Herrmann, C, Gremer, L, Vetter, I.R, Wittinghofer, A, Koenig, B, Kalbitzer, H.R.
Deposit date:2010-01-04
Release date:2011-01-05
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.44 Å)
Cite:Stabilizing a weak binding state for effectors in the human ras protein by cyclen complexes
Angew.Chem.Int.Ed.Engl., 49, 2010
2A78
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BU of 2a78 by Molmil
Crystal structure of the C3bot-RalA complex reveals a novel type of action of a bacterial exoenzyme
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Mono-ADP-ribosyltransferase C3, ...
Authors:Pautsch, A, Vogelsgesang, M, Trankle, J, Herrmann, C, Aktories, K.
Deposit date:2005-07-05
Release date:2005-10-11
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Crystal structure of the C3bot-RalA complex reveals a novel type of action of a bacterial exoenzyme.
Embo J., 24, 2005
2A9K
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BU of 2a9k by Molmil
Crystal structure of the C3bot-NAD-RalA complex reveals a novel type of action of a bacterial exoenzyme
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Mono-ADP-ribosyltransferase C3, ...
Authors:Pautsch, A, Vogelsgesang, M, Trankle, J, Herrmann, C, Aktories, K.
Deposit date:2005-07-12
Release date:2005-10-11
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Crystal structure of the C3bot-RalA complex reveals a novel type of action of a bacterial exoenzyme.
Embo J., 24, 2005
1IAQ
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BU of 1iaq by Molmil
C-H-RAS P21 PROTEIN MUTANT WITH THR 35 REPLACED BY SER (T35S) COMPLEXED WITH GUANOSINE-5'-[B,G-IMIDO] TRIPHOSPHATE
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, TRANSFORMING PROTEIN P21/H-RAS-1
Authors:Spoerner, M, Herrmann, C, Vetter, I.R, Kalbitzer, H.R, Wittinghofer, A.
Deposit date:2001-03-23
Release date:2001-06-06
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Dynamic properties of the Ras switch I region and its importance for binding to effectors.
Proc.Natl.Acad.Sci.USA, 98, 2001
1TQ2
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BU of 1tq2 by Molmil
Crystal Structure of IIGP1: a paradigm for interferon inducible p47 resistance GTPases
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
Authors:Ghosh, A, Uthaiah, R, Howard, J, Herrmann, C, Wolf, E.
Deposit date:2004-06-16
Release date:2004-09-21
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal Structure of IIGP1; A Paradigm for Interferon-Inducible p47 Resistance GTPases
Mol.Cell, 15, 2004
1TQ6
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BU of 1tq6 by Molmil
Crystal Structure of IIGP1: a paradigm for interferon inducible p47 resistance GTPases
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, interferon-inducible GTPase
Authors:Ghosh, A, Uthaiah, R, Howard, J, Herrmann, C, Wolf, E.
Deposit date:2004-06-16
Release date:2004-09-21
Last modified:2021-11-10
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal Structure of IIGP1; A Paradigm for Interferon-Inducible p47 Resistance GTPases
Mol.Cell, 15, 2004

 

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