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1BY9
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BU of 1by9 by Molmil
CRYSTAL STRUCTURE OF THE E2 DNA-BINDING DOMAIN FROM HUMAN PAPILLOMAVIRUS TYPE-16: IMPLICATIONS FOR ITS DNA BINDING-SITE SELECTION MECHANISM
Descriptor: REGULATORY PROTEIN E2
Authors:Hegde, R.S, Androphy, E.J.
Deposit date:1998-10-27
Release date:1999-04-27
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of the E2 DNA-binding domain from human papillomavirus type 16: implications for its DNA binding-site selection mechanism.
J.Mol.Biol., 284, 1998
2BOP
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BU of 2bop by Molmil
CRYSTAL STRUCTURE AT 1.7 ANGSTROMS OF THE BOVINE PAPILLOMAVIRUS-1 E2 DNA-BINDING DOMAIN BOUND TO ITS DNA TARGET
Descriptor: DNA (5'-D(*CP*CP*GP*AP*CP*CP*GP*AP*CP*GP*TP*CP*GP*GP*TP*CP*G )-3'), PROTEIN (E2), YTTERBIUM (III) ION
Authors:Hegde, R.S, Grossman, S.R, Laimins, L.A, Sigler, P.B.
Deposit date:1994-01-13
Release date:1994-01-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure at 1.7 A of the bovine papillomavirus-1 E2 DNA-binding domain bound to its DNA target.
Nature, 359, 1992
1JJH
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BU of 1jjh by Molmil
E2 DNA-binding Domain from Bovine Papillomavirus Type 1
Descriptor: REGULATORY PROTEIN E2
Authors:Hegde, R.S, Wang, A.F, Kim, S.S, Schapira, M.
Deposit date:2001-07-05
Release date:2001-07-18
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Subunit rearrangement accompanies sequence-specific DNA binding by the bovine papillomavirus-1 E2 protein.
J.Mol.Biol., 276, 1998
6Y4L
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BU of 6y4l by Molmil
Crystal structure of human ER membrane protein complex subunits EMC2 and EMC9
Descriptor: 1,2-ETHANEDIOL, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, DI(HYDROXYETHYL)ETHER, ...
Authors:Hegde, R.S, O'Donnell, J.P.
Deposit date:2020-02-21
Release date:2020-05-27
Last modified:2020-06-10
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The architecture of EMC reveals a path for membrane protein insertion.
Elife, 9, 2020
6Z3W
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BU of 6z3w by Molmil
Human ER membrane protein complex
Descriptor: ER membrane protein complex subunit 1,ER membrane protein complex subunit 1,ER membrane protein complex subunit 1,ER membrane protein complex subunit 1, ER membrane protein complex subunit 10, ER membrane protein complex subunit 2, ...
Authors:Hegde, R.S, O'Donnell, J.P.
Deposit date:2020-05-22
Release date:2020-07-15
Method:ELECTRON MICROSCOPY (6.4 Å)
Cite:The architecture of EMC reveals a path for membrane protein insertion.
Elife, 9, 2020
2F61
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BU of 2f61 by Molmil
Crystal structure of partially deglycosylated acid beta-glucosidase
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Acid beta-glucosidase, ...
Authors:Hegde, R.S, Grabowski, G.
Deposit date:2005-11-28
Release date:2005-12-27
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Analyses of Variant Acid beta-Glucosidases: EFFECTS OF GAUCHER DISEASE MUTATIONS.
J.Biol.Chem., 281, 2006
8BPO
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BU of 8bpo by Molmil
Structure of rabbit 80S ribosome translating beta-tubulin in complex with tetratricopeptide protein 5 (TTC5) and S-phase Cyclin A Associated Protein residing in the ER (SCAPER)
Descriptor: 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ...
Authors:Hopfler, M, Absmeier, E, Passmore, L.A, Hegde, R.S.
Deposit date:2022-11-17
Release date:2023-07-05
Last modified:2023-07-19
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Mechanism of ribosome-associated mRNA degradation during tubulin autoregulation.
Mol.Cell, 83, 2023
8RJC
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BU of 8rjc by Molmil
Structure of the rabbit 80S ribosome stalled on a 2-TMD rhodopsin intermediate in complex with Sec61-TRAP, open conformation 1
Descriptor: 28S rRNA, 5.8S rRNA, 5S rRNA, ...
Authors:Lewis, A.J.O, Hegde, R.S.
Deposit date:2023-12-20
Release date:2024-01-24
Method:ELECTRON MICROSCOPY (2.90061 Å)
Cite:Structure of the rabbit 80S ribosome stalled on a 2-TMD rhodopsin intermediate in complex with Sec61-TRAP, open conformation 1
To Be Published
8RJB
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BU of 8rjb by Molmil
Structure of the rabbit 80S ribosome stalled on a 2-TMD rhodopsin intermediate in complex with Sec61-RAMP4
Descriptor: 28S rRNA, 5.8S rRNA, 5S rRNA, ...
Authors:Lewis, A.J.O, Hegde, R.S.
Deposit date:2023-12-20
Release date:2024-01-24
Method:ELECTRON MICROSCOPY (2.69243 Å)
Cite:Structure of the rabbit 80S ribosome stalled on a 2-TMD rhodopsin intermediate in complex with Sec61-RAMP4
To Be Published
8RJD
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BU of 8rjd by Molmil
Structure of the rabbit 80S ribosome stalled on a 2-TMD rhodopsin intermediate in complex with Sec61-TRAP, open conformation 2
Descriptor: 28S rRNA, 5.8S rRNA, 5S rRNA, ...
Authors:Lewis, A.J.O, Hegde, R.S.
Deposit date:2023-12-20
Release date:2024-01-24
Method:ELECTRON MICROSCOPY (2.78574 Å)
Cite:Structure of the rabbit 80S ribosome stalled on a 2-TMD rhodopsin intermediate in complex with Sec61-TRAP, open conformation 2
To Be Published
7TUT
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BU of 7tut by Molmil
Structure of the rabbit 80S ribosome stalled on a 4-TMD Rhodopsin intermediate in complex with the multipass translocon
Descriptor: 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ...
Authors:Kim, M.K, Lewis, A.J.O, Keenan, R.J, Hegde, R.S.
Deposit date:2022-02-03
Release date:2022-10-19
Last modified:2022-11-16
Method:ELECTRON MICROSCOPY (3.88 Å)
Cite:Mechanism of an intramembrane chaperone for multipass membrane proteins.
Nature, 611, 2022
6HCF
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BU of 6hcf by Molmil
Structure of the rabbit 80S ribosome stalled on globin mRNA at the stop codon
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ...
Authors:Juszkiewicz, S, Chandrasekaran, V, Lin, Z, Kraatz, S, Ramakrishnan, V, Hegde, R.S.
Deposit date:2018-08-14
Release date:2018-10-17
Last modified:2019-01-23
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:ZNF598 Is a Quality Control Sensor of Collided Ribosomes.
Mol. Cell, 72, 2018
6HCQ
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BU of 6hcq by Molmil
Structure of the rabbit collided di-ribosome (collided monosome)
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ...
Authors:Juszkiewicz, S, Chandrasekaran, V, Lin, Z, Kraatz, S, Ramakrishnan, V, Hegde, R.S.
Deposit date:2018-08-16
Release date:2018-10-17
Last modified:2018-11-14
Method:ELECTRON MICROSCOPY (6.5 Å)
Cite:ZNF598 Is a Quality Control Sensor of Collided Ribosomes.
Mol. Cell, 72, 2018
6HCJ
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BU of 6hcj by Molmil
Structure of the rabbit 80S ribosome on globin mRNA in the rotated state with A/P and P/E tRNAs
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ...
Authors:Juszkiewicz, S, Chandrasekaran, V, Lin, Z, Kraatz, S, Ramakrishnan, V, Hegde, R.S.
Deposit date:2018-08-15
Release date:2018-10-17
Last modified:2018-11-14
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:ZNF598 Is a Quality Control Sensor of Collided Ribosomes.
Mol. Cell, 72, 2018
6HCM
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BU of 6hcm by Molmil
Structure of the rabbit collided di-ribosome (stalled monosome)
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ...
Authors:Juszkiewicz, S, Chandrasekaran, V, Lin, Z, Kraatz, S, Ramakrishnan, V, Hegde, R.S.
Deposit date:2018-08-15
Release date:2018-10-17
Last modified:2019-01-23
Method:ELECTRON MICROSCOPY (6.8 Å)
Cite:ZNF598 Is a Quality Control Sensor of Collided Ribosomes.
Mol. Cell, 72, 2018
2OQS
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BU of 2oqs by Molmil
Structure of the hDLG/SAP97 PDZ2 in complex with HPV-18 papillomavirus E6 peptide
Descriptor: C-terminal HPV-18 E6 peptide, Disks large homolog 1
Authors:Liu, Y, Baleja, J.D, Henry, G.D, Hegde, R.S.
Deposit date:2007-02-01
Release date:2007-09-04
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Solution structure of the hDlg/SAP97 PDZ2 domain and its mechanism of interaction with HPV-18 papillomavirus E6 protein.
Biochemistry, 46, 2007
5LZU
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BU of 5lzu by Molmil
Structure of the mammalian ribosomal termination complex with accommodated eRF1
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ...
Authors:Shao, S, Murray, J, Brown, A, Taunton, J, Ramakrishnan, V, Hegde, R.S.
Deposit date:2016-10-02
Release date:2016-11-30
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.75 Å)
Cite:Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes.
Cell, 167, 2016
5LZT
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BU of 5lzt by Molmil
Structure of the mammalian ribosomal termination complex with eRF1 and eRF3.
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 5.8S ribosomal RNA, ...
Authors:Shao, S, Murray, J, Brown, A, Taunton, J, Ramakrishnan, V, Hegde, R.S.
Deposit date:2016-10-02
Release date:2016-11-30
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.65 Å)
Cite:Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes.
Cell, 167, 2016
5LZS
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BU of 5lzs by Molmil
Structure of the mammalian ribosomal elongation complex with aminoacyl-tRNA, eEF1A, and didemnin B
Descriptor: (2~{S})-~{N}-[(2~{R})-1-[[(3~{S},6~{S},8~{S},12~{S},13~{R},16~{S},17~{R},20~{S},23~{S})-13-[(2~{S})-butan-2-yl]-20-[(4-methoxyphenyl)methyl]-6,17,21-trimethyl-3-(2-methylpropyl)-12-oxidanyl-2,5,7,10,15,19,22-heptakis(oxidanylidene)-8-propan-2-yl-9,18-dioxa-1,4,14,21-tetrazabicyclo[21.3.0]hexacosan-16-yl]amino]-4-methyl-1-oxidanylidene-pentan-2-yl]-~{N}-methyl-1-[(2~{S})-2-oxidanylpropanoyl]pyrrolidine-2-carboxamide, 18S ribosomal RNA, 28S ribosomal RNA, ...
Authors:Shao, S, Murray, J, Brown, A, Taunton, J, Ramakrishnan, V, Hegde, R.S.
Deposit date:2016-10-02
Release date:2016-11-30
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.31 Å)
Cite:Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes.
Cell, 167, 2016
3ZQ6
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BU of 3zq6 by Molmil
ADP-ALF4 COMPLEX OF M. THERM. TRC40
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, POTASSIUM ION, ...
Authors:Sherrill, J, Mariappan, M, Dominik, P, Hegde, R.S, Keenan, R.J.
Deposit date:2011-06-08
Release date:2011-06-22
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.107 Å)
Cite:A Conserved Archaeal Pathway for Tail-Anchored Membrane Protein Insertion.
Traffic, 12, 2011
3ZS9
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BU of 3zs9 by Molmil
S. cerevisiae Get3-ADP-AlF4- complex with a cytosolic Get2 fragment
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATPASE GET3, GOLGI TO ER TRAFFIC PROTEIN 2, ...
Authors:Mariappan, M, Mateja, A, Dobosz, M, Bove, E, Hegde, R.S, Keenan, R.J.
Deposit date:2011-06-24
Release date:2011-09-07
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.095 Å)
Cite:The Mechanism of Membrane-Associated Steps in Tail-Anchored Protein Insertion.
Nature, 477, 2011
3ZS8
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BU of 3zs8 by Molmil
S. cerevisiae Get3 complexed with a cytosolic Get1 fragment
Descriptor: ATPASE GET3, GOLGI TO ER TRAFFIC PROTEIN 1, ZINC ION
Authors:Mariappan, M, Mateja, A, Dobosz, M, Bove, E, Hegde, R.S, Keenan, R.J.
Deposit date:2011-06-24
Release date:2011-09-07
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:The Mechanism of Membrane-Associated Steps in Tail-Anchored Protein Insertion.
Nature, 477, 2011
4XTR
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BU of 4xtr by Molmil
Structure of Get3 bound to the transmembrane domain of Pep12
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATPase GET3, ...
Authors:Mateja, A, Paduch, M, Chang, H.-Y, Szydlowska, A, Kossiakoff, A.A, Hegde, R.S, Keenan, R.J.
Deposit date:2015-01-23
Release date:2015-03-18
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Protein targeting. Structure of the Get3 targeting factor in complex with its membrane protein cargo.
Science, 347, 2015
4XVU
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BU of 4xvu by Molmil
Structure of Get3 bound to the transmembrane domain of Nyv1
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, ATPase GET3, Antibody heavy chain, ...
Authors:Mateja, A, Paduch, M, Chang, H.-Y, Szydlowska, A, Kossiakoff, A.A, Hegde, R.S, Keenan, R.J.
Deposit date:2015-01-28
Release date:2015-03-18
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Protein targeting. Structure of the Get3 targeting factor in complex with its membrane protein cargo.
Science, 347, 2015
4XWO
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BU of 4xwo by Molmil
Structure of Get3 bound to the transmembrane domain of Sec22
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATPase GET3, ...
Authors:Mateja, A, Paduch, M, Chang, H.-Y, Szydlowska, A, Kossiakoff, A.A, Hegde, R.S, Keenan, R.J.
Deposit date:2015-01-29
Release date:2015-03-25
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Protein targeting. Structure of the Get3 targeting factor in complex with its membrane protein cargo.
Science, 347, 2015

 

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