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4V6V
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BU of 4v6v by Molmil
Tetracycline resistance protein Tet(O) bound to the ribosome
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Li, W, Atkinson, G.C, Thakor, N.S, Allas, U, Lu, C, Chan, K.Y, Tenson, T, Schulten, K, Wilson, K.S, Hauryliuk, V, Frank, J.
Deposit date:2013-02-25
Release date:2014-07-09
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (9.8 Å)
Cite:Mechanism of tetracycline resistance by ribosomal protection protein Tet(O).
Nat Commun, 4, 2013
7NHM
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BU of 7nhm by Molmil
70S ribosome from Staphylococcus aureus
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Crowe-McAuliffe, C, Murina, V, Hauryliuk, V, Wilson, D.N.
Deposit date:2021-02-10
Release date:2021-05-05
Last modified:2021-06-23
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis of ABCF-mediated resistance to pleuromutilin, lincosamide, and streptogramin A antibiotics in Gram-positive pathogens.
Nat Commun, 12, 2021
7NHL
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BU of 7nhl by Molmil
VgaA-LC, an antibiotic resistance ABCF, in complex with 70S ribosome from Staphylococcus aureus
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Crowe-McAuliffe, C, Murina, V, Hauryliuk, V, Wilson, D.N.
Deposit date:2021-02-10
Release date:2021-05-05
Last modified:2021-06-23
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis of ABCF-mediated resistance to pleuromutilin, lincosamide, and streptogramin A antibiotics in Gram-positive pathogens.
Nat Commun, 12, 2021
6S47
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BU of 6s47 by Molmil
Saccharomyces cerevisiae 80S ribosome bound with ABCF protein New1
Descriptor: 18S rRNA (1707-MER), 28S ribosomal RNA, 40S ribosomal protein S0-A, ...
Authors:Kasari, V, Pochopien, A.A, Margus, T, Murina, V, Turnbull, K, Zhou, Y, Nissan, T, Graf, M, Novacek, J, Atkinson, G.C, Johansson, M.J.O, Wilson, D.N, Hauryliuk, V.
Deposit date:2019-06-26
Release date:2019-07-24
Last modified:2019-10-23
Method:ELECTRON MICROSCOPY (3.28 Å)
Cite:A role for the Saccharomyces cerevisiae ABCF protein New1 in translation termination/recycling.
Nucleic Acids Res., 47, 2019
7NHN
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BU of 7nhn by Molmil
VgaL, an antibiotic resistance ABCF, in complex with 70S ribosome from Listeria monocytogenes
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Crowe-McAuliffe, C, Turnbull, K.J, Hauryliuk, V, Wilson, D.N.
Deposit date:2021-02-10
Release date:2021-05-05
Last modified:2021-06-23
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural basis of ABCF-mediated resistance to pleuromutilin, lincosamide, and streptogramin A antibiotics in Gram-positive pathogens.
Nat Commun, 12, 2021
3MCA
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BU of 3mca by Molmil
Structure of the Dom34-Hbs1 Complex and implications for its role in No-Go decay
Descriptor: Elongation factor 1 alpha-like protein, Protein dom34
Authors:Chen, L, Song, H.
Deposit date:2010-03-28
Release date:2010-10-06
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.74 Å)
Cite:Structure of the Dom34-Hbs1 complex and implications for no-go decay
Nat.Struct.Mol.Biol., 17, 2010
8BUU
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BU of 8buu by Molmil
ARE-ABCF VmlR2 bound to a 70S ribosome
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Crowe-McAuliffe, C, Wilson, D.N.
Deposit date:2022-11-30
Release date:2023-04-05
Last modified:2023-05-31
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Genome-encoded ABCF factors implicated in intrinsic antibiotic resistance in Gram-positive bacteria: VmlR2, Ard1 and CplR.
Nucleic Acids Res., 51, 2023
7NHK
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BU of 7nhk by Molmil
LsaA, an antibiotic resistance ABCF, in complex with 70S ribosome from Enterococcus faecalis
Descriptor: 1,4-DIAMINOBUTANE, 16S rRNA, 23S rRNA, ...
Authors:Crowe-McAuliffe, C, Kasari, M, Hauryliuk, V.H, Wilson, D.N.
Deposit date:2021-02-10
Release date:2021-05-05
Last modified:2021-06-23
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural basis of ABCF-mediated resistance to pleuromutilin, lincosamide, and streptogramin A antibiotics in Gram-positive pathogens.
Nat Commun, 12, 2021
6HA8
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BU of 6ha8 by Molmil
Cryo-EM structure of the ABCF protein VmlR bound to the Bacillus subtilis ribosome
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Crowe-McAuliffe, C, Graf, M, Huter, P, Abdelshahid, M, Novacek, J, Wilson, D.N.
Deposit date:2018-08-07
Release date:2018-08-29
Last modified:2021-01-27
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural basis for antibiotic resistance mediated by theBacillus subtilisABCF ATPase VmlR.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6HA1
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BU of 6ha1 by Molmil
Cryo-EM structure of a 70S Bacillus subtilis ribosome translating the ErmD leader peptide in complex with telithromycin
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Crowe-McAuliffe, C, Graf, M, Huter, P, Abdelshahid, M, Novacek, J, Wilson, D.N.
Deposit date:2018-08-07
Release date:2018-08-29
Last modified:2021-01-27
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis for antibiotic resistance mediated by theBacillus subtilisABCF ATPase VmlR.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
7P7Q
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BU of 7p7q by Molmil
E. faecalis 70S ribosome bound by PoxtA-EQ2, high-resolution combined volume
Descriptor: 1,4-DIAMINOBUTANE, 16S rRNA, 23S rRNA, ...
Authors:Crowe-McAuliffe, C, Wilson, D.N.
Deposit date:2021-07-20
Release date:2022-02-23
Last modified:2022-12-07
Method:ELECTRON MICROSCOPY (2.4 Å)
Cite:Structural basis for PoxtA-mediated resistance to phenicol and oxazolidinone antibiotics.
Nat Commun, 13, 2022
7P7U
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BU of 7p7u by Molmil
E. faecalis 70S ribosome with P-tRNA, state IV
Descriptor: 1,4-DIAMINOBUTANE, 16S rRNA, 23S rRNA, ...
Authors:Crowe-McAuliffe, C, Wilson, D.N.
Deposit date:2021-07-20
Release date:2022-02-23
Last modified:2022-04-20
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis for PoxtA-mediated resistance to phenicol and oxazolidinone antibiotics.
Nat Commun, 13, 2022
7P7T
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BU of 7p7t by Molmil
PoxtA-EQ2 antibiotic resistance ABCF bound to E. faecalis 70S ribosome, state III
Descriptor: 1,4-DIAMINOBUTANE, 16S rRNA, 23S rRNA, ...
Authors:Crowe-McAuliffe, C, Wilson, D.N.
Deposit date:2021-07-20
Release date:2022-02-23
Last modified:2022-04-20
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural basis for PoxtA-mediated resistance to phenicol and oxazolidinone antibiotics.
Nat Commun, 13, 2022
7P7S
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BU of 7p7s by Molmil
PoxtA-EQ2 antibiotic resistance ABCF bound to E. faecalis 70S ribosome, state II
Descriptor: 1,4-DIAMINOBUTANE, 16S rRNA, 23S rRNA, ...
Authors:Crowe-McAuliffe, C, Wilson, D.N.
Deposit date:2021-07-20
Release date:2022-02-23
Last modified:2022-04-20
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural basis for PoxtA-mediated resistance to phenicol and oxazolidinone antibiotics.
Nat Commun, 13, 2022
7P7R
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BU of 7p7r by Molmil
PoxtA-EQ2 antibiotic resistance ABCF bound to E. faecalis 70S ribosome, state I
Descriptor: 1,4-DIAMINOBUTANE, 16S rRNA, 23S rRNA, ...
Authors:Crowe-McAuliffe, C, Wilson, D.N.
Deposit date:2021-07-20
Release date:2022-03-23
Last modified:2022-04-20
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural basis for PoxtA-mediated resistance to phenicol and oxazolidinone antibiotics.
Nat Commun, 13, 2022
7AS9
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BU of 7as9 by Molmil
Bacillus subtilis ribosome-associated quality control complex state A. Ribosomal 50S subunit with peptidyl tRNA in the A/P position and RqcH.
Descriptor: 23S rRNA, 50S ribosomal protein L10, 50S ribosomal protein L11, ...
Authors:Crowe-McAuliffe, C, Wilson, D.N.
Deposit date:2020-10-27
Release date:2020-12-23
Last modified:2021-01-20
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural Basis for Bacterial Ribosome-Associated Quality Control by RqcH and RqcP.
Mol.Cell, 81, 2021
7ASA
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BU of 7asa by Molmil
Bacillus subtilis ribosome-associated quality control complex state B, multibody refinement focussed on RqcH. Ribosomal 50S subunit with P-tRNA, RqcH, and RqcP/YabO
Descriptor: 23S rRNA, 50S ribosomal protein L11, Rqc2 homolog RqcH, ...
Authors:Crowe-McAuliffe, C, Wilson, D.N.
Deposit date:2020-10-27
Release date:2020-12-23
Last modified:2021-01-20
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural Basis for Bacterial Ribosome-Associated Quality Control by RqcH and RqcP.
Mol.Cell, 81, 2021
7AS8
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BU of 7as8 by Molmil
Bacillus subtilis ribosome quality control complex state B. Ribosomal 50S subunit with P-tRNA, RqcH, and RqcP/YabO
Descriptor: 23S rRNA, 50S ribosomal protein L10, 50S ribosomal protein L11, ...
Authors:Crowe-McAuliffe, C, Wilson, D.N.
Deposit date:2020-10-27
Release date:2020-12-09
Last modified:2021-01-20
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural Basis for Bacterial Ribosome-Associated Quality Control by RqcH and RqcP.
Mol.Cell, 81, 2021
5L3P
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BU of 5l3p by Molmil
Cryo-EM structure of stringent response factor RelA bound to ErmCL-stalled ribosome complex
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Arenz, S, Wilson, D.N.
Deposit date:2016-05-24
Release date:2016-07-20
Last modified:2019-10-02
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:The stringent factor RelA adopts an open conformation on the ribosome to stimulate ppGpp synthesis.
Nucleic Acids Res., 44, 2016
7OPE
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BU of 7ope by Molmil
RqcH DR variant bound to 50S-peptidyl-tRNA-RqcP RQC complex (rigid body refinement)
Descriptor: 23S rRNA, 50S ribosomal protein L10, 50S ribosomal protein L11, ...
Authors:Crowe-McAuliffe, C, Wilson, D.N.
Deposit date:2021-05-31
Release date:2021-07-21
Last modified:2021-09-22
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:RqcH and RqcP catalyze processive poly-alanine synthesis in a reconstituted ribosome-associated quality control system.
Nucleic Acids Res., 49, 2021
7P48
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BU of 7p48 by Molmil
Staphylococcus aureus ribosome in complex with Sal(B)
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Nicholson, D, Ranson, N.A, O'Neill, A.J.
Deposit date:2021-07-09
Release date:2022-02-02
Last modified:2022-03-09
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Sal-type ABC-F proteins: intrinsic and common mediators of pleuromutilin resistance by target protection in staphylococci.
Nucleic Acids Res., 50, 2022
6EX0
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BU of 6ex0 by Molmil
Crystal structure of RelP (SAS2) from Staphylococcus aureus bound to pppGpp in the post-catalytic state
Descriptor: FE (II) ION, GTP pyrophosphokinase, guanosine 5'-(tetrahydrogen triphosphate) 3'-(trihydrogen diphosphate)
Authors:Manav, M.C, Brodersen, D.E.
Deposit date:2017-11-07
Release date:2018-01-24
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.78 Å)
Cite:Structural basis for (p)ppGpp synthesis by theStaphylococcus aureussmall alarmone synthetase RelP.
J. Biol. Chem., 293, 2018
6EWZ
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BU of 6ewz by Molmil
Crystal structure of RelP (SAS2) from Staphylococcus aureus bound to AMPCPP and GTP in the pre-catalytic state
Descriptor: DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, FE (III) ION, GTP pyrophosphokinase, ...
Authors:Manav, M.C, Brodersen, D.E.
Deposit date:2017-11-07
Release date:2018-01-24
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:Structural basis for (p)ppGpp synthesis by theStaphylococcus aureussmall alarmone synthetase RelP.
J. Biol. Chem., 293, 2018
8A63
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BU of 8a63 by Molmil
Cryo-EM structure of Listeria monocytogenes 50S ribosomal subunit.
Descriptor: 1,4-DIAMINOBUTANE, 23S ribosomal RNA, 50S ribosomal protein L13, ...
Authors:Koller, T.O, Crowe-McAuliffe, C, Wilson, D.N.
Deposit date:2022-06-16
Release date:2022-11-02
Last modified:2022-11-16
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis for HflXr-mediated antibiotic resistance in Listeria monocytogenes.
Nucleic Acids Res., 50, 2022
8A5I
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BU of 8a5i by Molmil
Cryo-EM structure of Lincomycin bound to the Listeria monocytogenes 50S ribosomal subunit.
Descriptor: 1,4-DIAMINOBUTANE, 23S ribosomal RNA, 50S ribosomal protein L13, ...
Authors:Koller, T.O, Crowe-McAuliffe, C, Wilson, D.N.
Deposit date:2022-06-15
Release date:2022-11-02
Last modified:2022-11-16
Method:ELECTRON MICROSCOPY (2.3 Å)
Cite:Structural basis for HflXr-mediated antibiotic resistance in Listeria monocytogenes.
Nucleic Acids Res., 50, 2022

 

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