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2D10
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CRYSTAL STRUCTURE OF THE RADIXIN FERM DOMAIN COMPLEXED WITH THE NHERF-1 C-TERMINAL TAIL PEPTIDE
Descriptor:Radixin, Ezrin-radixin-moesin binding phosphoprotein 50
Authors:Terawaki, S., Maesaki, R., Hakoshima, T.
Deposit date:2005-08-11
Release date:2006-07-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for NHERF recognition by ERM proteins
Structure, 14, 2006
2D11
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CRYSTAL STRUCTURE OF THE RADIXIN FERM DOMAIN COMPLEXED WITH THE NHERF-2 C-TERMINAL TAIL PEPTIDE
Descriptor:Radixin, Na(+)/H(+) exchange regulatory cofactor NHE-RF2
Authors:Terawaki, S., Maesaki, R., Hakoshima, T.
Deposit date:2005-08-11
Release date:2006-07-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Structural basis for NHERF recognition by ERM proteins
Structure, 14, 2006
2YVC
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CRYSTAL STRUCTURE OF THE RADIXIN FERM DOMAIN COMPLEXED WITH THE NEP CYTOPLASMIC TAIL
Descriptor:Radixin, Neprilysin
Authors:Terawaki, S., Kitano, K., Hakoshima, T.
Deposit date:2007-04-11
Release date:2007-04-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural basis for type II membrane protein binding by ERM proteins revealed by the radixin-neutral endopeptidase 24.11 (NEP) complex
J.Biol.Chem., 282, 2007
2A0B
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HISTIDINE-CONTAINING PHOSPHOTRANSFER DOMAIN OF ARCB FROM ESCHERICHIA COLI
Descriptor:HPT DOMAIN, ZINC ION
Authors:Kato, M., Mizuno, T., Shimizu, T., Hakoshima, T.
Deposit date:1998-04-02
Release date:1998-06-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:Refined structure of the histidine-containing phosphotransfer (HPt) domain of the anaerobic sensor kinase ArcB from Escherichia coli at 1.57 A resolution.
Acta Crystallogr.,Sect.D, 55, 1999
1A0B
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HISTIDINE-CONTAINING PHOSPHOTRANSFER DOMAIN OF ARCB FROM ESCHERICHIA COLI
Descriptor:AEROBIC RESPIRATION CONTROL SENSOR PROTEIN ARCB, ZINC ION
Authors:Kato, M., Mizuno, T., Shimizu, T., Hakoshima, T.
Deposit date:1997-11-27
Release date:1998-03-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Insights into multistep phosphorelay from the crystal structure of the C-terminal HPt domain of ArcB.
Cell(Cambridge,Mass.), 88, 1997
1GC6
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CRYSTAL STRUCTURE OF THE RADIXIN FERM DOMAIN COMPLEXED WITH INOSITOL-(1,4,5)-TRIPHOSPHATE
Descriptor:RADIXIN, D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE
Authors:Hamada, K., Shimizu, T., Matsui, T., Tsukita, S., Tsukita, S., Hakoshima, T.
Deposit date:2000-07-21
Release date:2000-09-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis of the membrane-targeting and unmasking mechanisms of the radixin FERM domain.
EMBO J., 19, 2000
1GC7
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CRYSTAL STRUCTURE OF THE RADIXIN FERM DOMAIN
Descriptor:RADIXIN
Authors:Hamada, K., Shimizu, T., Matsui, T., Tsukita, S., Tsukita, S., Hakoshima, T.
Deposit date:2000-07-21
Release date:2000-09-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis of the membrane-targeting and unmasking mechanisms of the radixin FERM domain.
EMBO J., 19, 2000
1GD2
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CRYSTAL STRUCTURE OF BZIP TRANSCRIPTION FACTOR PAP1 BOUND TO DNA
Descriptor:DNA (5'-D(*AP*GP*GP*TP*TP*AP*CP*GP*TP*AP*AP*CP*C)-3'), TRANSCRIPTION FACTOR PAP1
Authors:Fujii, Y., Shimizu, T., Toda, T., Yanagida, M., Hakoshima, T.
Deposit date:2000-08-25
Release date:2000-10-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for the diversity of DNA recognition by bZIP transcription factors.
Nat.Struct.Biol., 7, 2000
1NPM
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NEUROPSIN, A SERINE PROTEASE EXPRESSED IN THE LIMBIC SYSTEM OF MOUSE BRAIN
Descriptor:NEUROPSIN, N-ACETYL-D-GLUCOSAMINE
Authors:Kishi, T., Kato, M., Shimizu, T., Kato, K., Matsumoto, K., Yoshida, S., Shiosaka, S., Hakoshima, T.
Deposit date:1998-01-07
Release date:1999-03-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of neuropsin, a hippocampal protease involved in kindling epileptogenesis.
J.Biol.Chem., 274, 1999
1UJB
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STRUCTURE OF THE PROTEIN HISTIDINE PHOSPHATASE SIXA
Descriptor:Phosphohistidine phosphatase sixA, CALCIUM ION
Authors:Hamada, K., Kato, M., Shimizu, T., Ihara, K., Mizuno, T., Hakoshima, T.
Deposit date:2003-07-31
Release date:2005-01-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Crystal structure of the protein histidine phosphatase SixA in the multistep His-Asp phosphorelay.
Genes Cells, 10, 2005
1UJC
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STRUCTURE OF THE PROTEIN HISTIDINE PHOSPHATASE SIXA COMPLEXED WITH TUNGSTATE
Descriptor:Phosphohistidine phosphatase sixA, CALCIUM ION, TUNGSTATE(VI)ION
Authors:Hamada, K., Kato, M., Shimizu, T., Ihara, K., Mizuno, T., Hakoshima, T.
Deposit date:2003-07-31
Release date:2005-01-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of the protein histidine phosphatase SixA in the multistep His-Asp phosphorelay.
Genes Cells, 10, 2005
1CXZ
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CRYSTAL STRUCTURE OF HUMAN RHOA COMPLEXED WITH THE EFFECTOR DOMAIN OF THE PROTEIN KINASE PKN/PRK1
Descriptor:PROTEIN (HIS-TAGGED TRANSFORMING PROTEIN RHOA(0-181)), PROTEIN (PKN), MAGNESIUM ION, ...
Authors:Maesaki, R., Ihara, K., Shimizu, T., Kuroda, S., Kaibuchi, K., Hakoshima, T.
Deposit date:1999-08-31
Release date:1999-10-08
Last modified:2018-03-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The structural basis of Rho effector recognition revealed by the crystal structure of human RhoA complexed with the effector domain of PKN/PRK1.
Mol.Cell, 4, 1999
1J19
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CRYSTAL STRUCTURE OF THE RADXIN FERM DOMAIN COMPLEXED WITH THE ICAM-2 CYTOPLASMIC PEPTIDE
Descriptor:radixin, 16-mer peptide from Intercellular adhesion molecule-2
Authors:Hamada, K., Shimizu, T., Yonemura, S., Tsukita, S., Tsukita, S., Hakoshima, T.
Deposit date:2002-12-02
Release date:2003-03-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis of adhesion-molecule recognition by ERM proteins revealed by the crystal structure of the radixin-ICAM-2 complex
EMBO J., 22, 2003
2EMS
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CRYSTAL STRUCTURE ANALYSIS OF THE RADIXIN FERM DOMAIN COMPLEXED WITH ADHESION MOLECULE CD43
Descriptor:Radixin, Leukosialin
Authors:Takai, Y., Kitano, K., Terawaki, S., Maesaki, R., Hakoshima, T.
Deposit date:2007-03-28
Release date:2008-04-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis of the cytoplasmic tail of adhesion molecule CD43 and its binding to ERM proteins
J.Mol.Biol., 381, 2008
2EMT
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CRYSTAL STRUCTURE ANALYSIS OF THE RADIXIN FERM DOMAIN COMPLEXED WITH ADHESION MOLECULE PSGL-1
Descriptor:Radixin, P-selectin glycoprotein ligand 1
Authors:Takai, Y., Kitano, K., Terawaki, S., Maesaki, R., Hakoshima, T.
Deposit date:2007-03-28
Release date:2008-03-18
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis of PSGL-1 binding to ERM proteins
Genes Cells, 12, 2007
1BDJ
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COMPLEX STRUCTURE OF HPT DOMAIN AND CHEY
Descriptor:CHEY, AEROBIC RESPIRATION CONTROL SENSOR PROTEIN ARCB, SULFATE ION
Authors:Kato, M., Mizuno, T., Shimizu, T., Hakoshima, T.
Deposit date:1998-05-10
Release date:1999-05-11
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:Structure of the histidine-containing phosphotransfer (HPt) domain of the anaerobic sensor protein ArcB complexed with the chemotaxis response regulator CheY.
Acta Crystallogr.,Sect.D, 55, 1999
2IRF
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CRYSTAL STRUCTURE OF AN IRF-2/DNA COMPLEX.
Descriptor:DNA (5'-D(P*AP*AP*GP*TP*GP*AP*AP*AP*GP*(5IU)P*GP*A)-3'), DNA (5'-D(*TP*TP*CP*AP*CP*TP*TP*TP*CP*AP*CP*(5IU)P*T)-3'), INTERFERON REGULATORY FACTOR 2, ...
Authors:Fujii, Y., Shimizu, T., Kusumoto, M., Kyogoku, Y., Taniguchi, T., Hakoshima, T.
Deposit date:1999-05-30
Release date:1999-10-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of an IRF-DNA complex reveals novel DNA recognition and cooperative binding to a tandem repeat of core sequences.
EMBO J., 18, 1999
3A8N
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CRYSTAL STRUCTURE OF THE TIAM1 PHCCEX DOMAIN
Descriptor:T-lymphoma invasion and metastasis-inducing protein 1
Authors:Terawaki, S., Kitano, K., Mori, T., Zhai, Y., Higuchi, Y., Itoh, N., Watanabe, T., Kaibuchi, K., Hakoshima, T.
Deposit date:2009-10-07
Release date:2009-11-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (4.5 Å)
Cite:The PHCCEx domain of Tiam1/2 is a novel protein- and membrane-binding module
Embo J., 29, 2010
3A8P
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CRYSTAL STRUCTURE OF THE TIAM2 PHCCEX DOMAIN
Descriptor:T-lymphoma invasion and metastasis-inducing protein 2
Authors:Terawaki, S., Kitano, K., Mori, T., Zhai, Y., Higuchi, Y., Itoh, N., Watanabe, T., Kaibuchi, K., Hakoshima, T.
Deposit date:2009-10-07
Release date:2009-11-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The PHCCEx domain of Tiam1/2 is a novel protein- and membrane-binding module
Embo J., 29, 2010
3A8Q
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LOW-RESOLUTION CRYSTAL STRUCTURE OF THE TIAM2 PHCCEX DOMAIN
Descriptor:T-lymphoma invasion and metastasis-inducing protein 2
Authors:Terawaki, S., Kitano, K., Mori, T., Zhai, Y., Higuchi, Y., Itoh, N., Watanabe, T., Kaibuchi, K., Hakoshima, T.
Deposit date:2009-10-07
Release date:2009-11-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:The PHCCEx domain of Tiam1/2 is a novel protein- and membrane-binding module
Embo J., 29, 2010
3W6S
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YEAST N-ACETYLTRANSFERASE MPR1 INVOLVED IN OXIDATIVE STRESS TOLERANCE VIA PROLINE METABOLISM
Descriptor:MPR1 protein, HEXAETHYLENE GLYCOL, MAGNESIUM ION
Authors:Nasuno, R., Hirano, Y., Itoh, T., Hakoshima, T., Hibi, T., Takagi, H.
Deposit date:2013-02-21
Release date:2013-07-17
Last modified:2013-08-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and functional analysis of the yeast N-acetyltransferase Mpr1 involved in oxidative stress tolerance via proline metabolism
Proc.Natl.Acad.Sci.USA, 110, 2013
3W6X
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YEAST N-ACETYLTRANSFERASE MPR1 IN COMPLEX WITH CHOP
Descriptor:MPR1 protein, (4S)-4-hydroxy-L-proline, HEXAETHYLENE GLYCOL, ...
Authors:Nasuno, R., Hirano, Y., Itoh, T., Hakoshima, T., Hibi, T., Takagi, H.
Deposit date:2013-02-25
Release date:2013-08-07
Method:X-RAY DIFFRACTION (2.299 Å)
Cite:Structural and functional analysis of the yeast N-acetyltransferase Mpr1 involved in oxidative stress tolerance via proline metabolism
Proc.Natl.Acad.Sci.USA, 110, 2013
3W91
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CRYSTAL STRUCTURE OF SEMET-LABELED YEAST N-ACETYLTRANSFERASE MPR1 L87M MUTANT
Descriptor:MPR1 protein
Authors:Nasuno, R., Hirano, Y., Itoh, T., Hakoshima, T., Hibi, T., Takagi, H.
Deposit date:2013-03-23
Release date:2013-07-17
Last modified:2013-08-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and functional analysis of the yeast N-acetyltransferase Mpr1 involved in oxidative stress tolerance via proline metabolism
Proc.Natl.Acad.Sci.USA, 110, 2013
3WX1
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MOUSE CEREBLON THALIDOMIDE BINDING DOMAIN, SELENOMETHIONINE DERIVATIVE
Descriptor:Protein cereblon, ZINC ION, SULFATE ION
Authors:Mori, T., Ito, T., Hirano, Y., Yamaguchi, Y., Handa, H., Hakoshima, T.
Deposit date:2014-07-10
Release date:2014-08-06
Last modified:2014-09-17
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Structure of the human Cereblon-DDB1-lenalidomide complex reveals basis for responsiveness to thalidomide analogs
Nat.Struct.Mol.Biol., 21, 2014
3WX2
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MOUSE CEREBLON THALIDOMIDE BINDING DOMAIN, NATIVE
Descriptor:Protein cereblon, ZINC ION, SULFATE ION
Authors:Mori, T., Ito, T., Hirano, Y., Yamaguchi, Y., Handa, H., Hakoshima, T.
Deposit date:2014-07-10
Release date:2014-08-06
Last modified:2014-09-17
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of the human Cereblon-DDB1-lenalidomide complex reveals basis for responsiveness to thalidomide analogs
Nat.Struct.Mol.Biol., 21, 2014
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