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6PBC
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BU of 6pbc by Molmil
Structural basis for the activation of PLC-gamma isozymes by phosphorylation and cancer-associated mutations
Descriptor: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma,1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1, CALCIUM ION, SODIUM ION
Authors:Hajicek, N, Sondek, J.
Deposit date:2019-06-13
Release date:2020-01-08
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.46 Å)
Cite:Structural basis for the activation of PLC-gamma isozymes by phosphorylation and cancer-associated mutations.
Elife, 8, 2019
4K44
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BU of 4k44 by Molmil
Auto-inhibition and phosphorylation-induced activation of PLC-gamma isozymes
Descriptor: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1
Authors:Hajicek, N, Sondek, J.
Deposit date:2013-04-11
Release date:2013-06-26
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Autoinhibition and Phosphorylation-Induced Activation of Phospholipase C-gamma Isozymes.
Biochemistry, 52, 2013
4K45
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BU of 4k45 by Molmil
Auto-inhibition and phosphorylation-induced activation of PLC-gamma isozymes
Descriptor: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1, short peptide
Authors:Sondek, J, Hajicek, N.
Deposit date:2013-04-11
Release date:2013-06-26
Last modified:2014-01-22
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Autoinhibition and Phosphorylation-Induced Activation of Phospholipase C-gamma Isozymes.
Biochemistry, 52, 2013
3AB3
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BU of 3ab3 by Molmil
Crystal structure of p115RhoGEF RGS domain in complex with G alpha 13
Descriptor: GUANOSINE-5'-DIPHOSPHATE, Guanine nucleotide-binding protein G(k) subunit alpha, Guanine nucleotide-binding protein subunit alpha-13, ...
Authors:Kukimoto-Niino, M, Mishima, C, Shirouzu, M, Kozasa, T, Yokoyama, S.
Deposit date:2009-11-30
Release date:2010-12-29
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Identification of critical residues in G(alpha)13 for stimulation of p115RhoGEF activity and the structure of the G(alpha)13-p115RhoGEF regulator of G protein signaling homology (RH) domain complex.
J.Biol.Chem., 286, 2011

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