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7MWC
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BU of 7mwc by Molmil
ERAP1 binds peptide C-terminus of a LPF sequence (AAAAFKARKF)
Descriptor: Endoplasmic reticulum aminopeptidase 1,LPF sequence
Authors:Guo, H.C, Sui, L.
Deposit date:2021-05-16
Release date:2021-07-28
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3 Å)
Cite:ERAP1 binds peptide C-termini of different sequences and/or lengths by a common recognition mechanism.
Immunobiology, 226, 2021
7MWB
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BU of 7mwb by Molmil
ERAP1 binds peptide C-terminus of a SPF sequence (FKARKF)
Descriptor: Endoplasmic reticulum aminopeptidase 1,SPF Sequence
Authors:Guo, H.C, Sui, L.
Deposit date:2021-05-16
Release date:2021-07-28
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:ERAP1 binds peptide C-termini of different sequences and/or lengths by a common recognition mechanism.
Immunobiology, 226, 2021
6NQ6
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BU of 6nq6 by Molmil
Structure & function of a new Aspartylglucosaminuria variant
Descriptor: N(4)-(Beta-N-acetylglucosaminyl)-L-asparaginase
Authors:Pande, S, Guo, H.C.
Deposit date:2019-01-19
Release date:2019-04-17
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The T99K variant of glycosylasparaginase shows a new structural mechanism of the genetic disease aspartylglucosaminuria.
Protein Sci., 28, 2019
4R4Y
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BU of 4r4y by Molmil
Structural basis of a point mutation that causes the genetic disease Aspartylglucosaminuria
Descriptor: N(4)-(Beta-N-acetylglucosaminyl)-L-asparaginase, N-hydroxy-L-asparagine
Authors:Sui, L, Damodharan, L, Pande, S, Guo, H.C.
Deposit date:2014-08-20
Release date:2014-12-17
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Basis of a Point Mutation that Causes the Genetic Disease Aspartylglucosaminuria.
Structure, 22, 2014
1SA3
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BU of 1sa3 by Molmil
An asymmetric complex of restriction endonuclease MspI on its palindromic DNA recognition site
Descriptor: 5'-D(*CP*CP*CP*CP*CP*GP*GP*GP*GP*G)-3', SODIUM ION, Type II restriction enzyme MspI
Authors:Xu, Q.S, Kucera, R.B, Roberts, R.J, Guo, H.C.
Deposit date:2004-02-06
Release date:2004-09-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:An Asymmetric Complex of Restriction Endonuclease MspI on Its Palindromic DNA Recognition Site.
STRUCTURE, 12, 2004
6DEY
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BU of 6dey by Molmil
Aspartylglucosaminuria mutant structure and function
Descriptor: Glycosylasparaginase, residues 188-331, residues 38-178
Authors:Pande, S, Laksminarasimhan, D, Guo, H.C.
Deposit date:2018-05-13
Release date:2018-08-01
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Biochemical and structural insights into an allelic variant causing the lysosomal storage disorder - aspartylglucosaminuria.
FEBS Lett., 592, 2018
2Q5Y
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BU of 2q5y by Molmil
Crystal Structure of the C-terminal domain of hNup98
Descriptor: Nuclear pore complex protein Nup96, Nuclear pore complex protein Nup98
Authors:Sun, Y, Guo, H.C.
Deposit date:2007-06-03
Release date:2008-10-14
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural constraints on autoprocessing of the human nucleoporin Nup98.
Protein Sci., 17, 2008
2Q5X
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BU of 2q5x by Molmil
Crystal Structure of the C-terminal domain of hNup98
Descriptor: Nuclear pore complex protein Nup98
Authors:Sun, Y, Guo, H.C.
Deposit date:2007-06-03
Release date:2008-10-14
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural constraints on autoprocessing of the human nucleoporin Nup98.
Protein Sci., 17, 2008
2GL9
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BU of 2gl9 by Molmil
Crystal Structure of Glycosylasparaginase-Substrate Complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ASPARAGINE, Glycosylasparaginase alpha chain, ...
Authors:Wang, Y, Guo, H.C.
Deposit date:2006-04-04
Release date:2007-02-13
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystallographic snapshot of a productive glycosylasparaginase-substrate complex.
J.Mol.Biol., 366, 2007
1P4V
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BU of 1p4v by Molmil
CRYSTAL STRUCTURE OF THE GLYCOSYLASPARAGINASE PRECURSOR D151N MUTANT WITH GLYCINE
Descriptor: GLYCINE, N(4)-(Beta-N-acetylglucosaminyl)-L-asparaginase precursor
Authors:Qian, X, Guan, C, Guo, H.C.
Deposit date:2003-04-24
Release date:2003-05-06
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A dual role for an aspartic acid in glycosylasparaginase autoproteolysis.
Structure, 11, 2003
1P4K
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BU of 1p4k by Molmil
CRYSTAL STRUCTURE OF THE GLYCOSYLASPARAGINASE PRECURSOR D151N MUTANT
Descriptor: GLYCEROL, N(4)-(Beta-N-acetylglucosaminyl)-L-asparaginase
Authors:Qian, X, Guan, C, Guo, H.C.
Deposit date:2003-04-23
Release date:2003-05-06
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A dual role for an aspartic acid in glycosylasparaginase autoproteolysis.
Structure, 11, 2003
1YU5
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BU of 1yu5 by Molmil
Crystal Structure of the Headpiece Domain of Chicken Villin
Descriptor: Villin
Authors:Meng, J, Vardar, D, Wang, Y, Guo, H.C, Head, J.F, McKnight, C.J.
Deposit date:2005-02-11
Release date:2005-09-06
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:High-resolution crystal structures of villin headpiece and mutants with reduced f-actin binding activity.
Biochemistry, 44, 2005
1YU8
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BU of 1yu8 by Molmil
Crystal Structure of the R37A Mutant of Villin Headpiece
Descriptor: Villin
Authors:Meng, J, Vardar, D, Wang, Y, Guo, H.C, Head, J.F, McKnight, C.J.
Deposit date:2005-02-12
Release date:2005-09-06
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:High-resolution crystal structures of villin headpiece and mutants with reduced F-actin binding activity.
Biochemistry, 44, 2005
1YU7
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BU of 1yu7 by Molmil
Crystal Structure of the W64Y mutant of Villin Headpiece
Descriptor: Villin
Authors:Meng, J, Vardar, D, Wang, Y, Guo, H.C, Head, J.F, McKnight, C.J.
Deposit date:2005-02-12
Release date:2005-09-06
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:High-resolution crystal structures of villin headpiece and mutants with reduced F-actin binding activity.
Biochemistry, 44, 2005
1HSB
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BU of 1hsb by Molmil
DIFFERENT LENGTH PEPTIDES BIND TO HLA-AW68 SIMILARLY AT THEIR ENDS BUT BULGE OUT IN THE MIDDLE
Descriptor: ALANINE, ARGININE, BETA 2-MICROGLOBULIN, ...
Authors:Guo, H.-C, Strominger, J.L, Wiley, D.C.
Deposit date:1993-03-30
Release date:1993-10-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Different length peptides bind to HLA-Aw68 similarly at their ends but bulge out in the middle.
Nature, 360, 1992
2GAW
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BU of 2gaw by Molmil
WILD TYPE GLYCOSYLASPARAGINASE FROM FLAVOBACTERIUM MENINGOSEPTICUM
Descriptor: GLYCOSYLASPARAGINASE
Authors:Guo, H.-C, Xu, Q.
Deposit date:1998-05-29
Release date:1999-06-08
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structures of Flavobacterium glycosylasparaginase. An N-terminal nucleophile hydrolase activated by intramolecular proteolysis.
J.Biol.Chem., 273, 1998
2GAC
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BU of 2gac by Molmil
T152C MUTANT GLYCOSYLASPARAGINASE FROM FLAVOBACTERIUM MENINGOSEPTICUM
Descriptor: GLYCOSYLASPARAGINASE
Authors:Guo, H.-C, Xu, Q.
Deposit date:1998-05-29
Release date:1999-06-08
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structures of Flavobacterium glycosylasparaginase. An N-terminal nucleophile hydrolase activated by intramolecular proteolysis.
J.Biol.Chem., 273, 1998
9GAF
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BU of 9gaf by Molmil
PRECURSOR OF THE W11F MUTANT GLYCOSYLASPARAGINASE FROM FLAVOBACTERIUM MENINGOSEPTICUM
Descriptor: GLYCINE, PROTEIN (GLYCOSYLASPARAGINASE)
Authors:Guo, H.-C, Xu, Q.
Deposit date:1999-06-15
Release date:2000-06-16
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural insights into the mechanism of intramolecular proteolysis.
Cell(Cambridge,Mass.), 98, 1999
9GAC
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BU of 9gac by Molmil
PRECURSOR OF THE T152C MUTANT GLYCOSYLASPARAGINASE FROM FLAVOBACTERIUM MENINGOSEPTICUM
Descriptor: GLYCINE, PROTEIN (GLYCOSYLASPARAGINASE)
Authors:Guo, H.-C, Xu, Q.
Deposit date:1999-06-15
Release date:2000-06-16
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural insights into the mechanism of intramolecular proteolysis.
Cell(Cambridge,Mass.), 98, 1999
9GAA
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BU of 9gaa by Molmil
PRECURSOR OF THE T152A MUTANT GLYCOSYLASPARAGINASE FROM FLAVOBACTERIUM MENINGOSEPTICUM
Descriptor: PROTEIN (GLYCOSYLASPARAGINASE)
Authors:Guo, H.-C, Xu, Q.
Deposit date:1999-06-15
Release date:2000-06-16
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural insights into the mechanism of intramolecular proteolysis.
Cell(Cambridge,Mass.), 98, 1999
1B0R
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BU of 1b0r by Molmil
CRYSTAL STRUCTURE OF HLA-A*0201 COMPLEXED WITH A PEPTIDE WITH THE CARBOXYL-TERMINAL GROUP SUBSTITUTED BY A METHYL GROUP
Descriptor: PROTEIN (HLA-A*0201), PROTEIN (INFLUENZA MATRIX PEPTIDE)
Authors:Bouvier, M, Guo, H, Smith, K.J, Wiley, D.C.
Deposit date:1998-11-12
Release date:1999-11-25
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structures of HLA-A*0201 complexed with antigenic peptides with either the amino- or carboxyl-terminal group substituted by a methyl group.
Proteins, 33, 1998
1JN9
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BU of 1jn9 by Molmil
Structure of Putative Asparaginase Encoded by Escherichia coli ybiK Gene
Descriptor: CALCIUM ION, CHLORIDE ION, PUTATIVE L-ASPARAGINASE, ...
Authors:Borek, D, Jaskolski, M.
Deposit date:2001-07-23
Release date:2003-09-09
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal packing of plant-type L-asparaginase from Escherichia coli.
Acta Crystallogr.,Sect.D, 64, 2008
1K2X
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BU of 1k2x by Molmil
Crystal structure of putative asparaginase encoded by Escherichia coli ybiK gene
Descriptor: CHLORIDE ION, Putative L-asparaginase, SODIUM ION
Authors:Borek, D, Jaskolski, M.
Deposit date:2001-09-30
Release date:2003-09-09
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal packing of plant-type L-asparaginase from Escherichia coli.
Acta Crystallogr.,Sect.D, 64, 2008
5V2I
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BU of 5v2i by Molmil
Crystal structure of a mutant glycosylasparaginase (G172D) that causes the genetic disease Aspartylglucosaminuria
Descriptor: Glycosylasparaginase
Authors:Pande, S, Guo, H.
Deposit date:2017-03-04
Release date:2017-05-17
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Crystal structure of a mutant glycosylasparaginase shedding light on aspartylglycosaminuria-causing mechanism as well as on hydrolysis of non-chitobiose substrate.
Mol. Genet. Metab., 121, 2017
5J5E
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BU of 5j5e by Molmil
crystal structure of antigen-ERAP1 domain complex
Descriptor: Endoplasmic reticulum aminopeptidase 1
Authors:Sui, L, Gandhi, A, Guo, H.-C.
Deposit date:2016-04-02
Release date:2017-04-12
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of a polypeptide's C-terminus in complex with the regulatory domain of ER aminopeptidase 1.
Mol.Immunol., 80, 2016

 

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