Author results

3TEC
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CALCIUM BINDING TO THERMITASE. CRYSTALLOGRAPHIC STUDIES OF THERMITASE AT 0, 5 AND 100 MM CALCIUM
Descriptor:THERMITASE, EGLIN C, CALCIUM ION
Authors:Gros, P., Kalk, K.H., Hol, W.G.J.
Deposit date:1990-10-26
Release date:1992-01-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Calcium binding to thermitase. Crystallographic studies of thermitase at 0, 5, and 100 mM calcium.
J.Biol.Chem., 266, 1991
1TEC
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CRYSTALLOGRAPHIC REFINEMENT BY INCORPORATION OF MOLECULAR DYNAMICS. THE THERMOSTABLE SERINE PROTEASE THERMITASE COMPLEXED WITH EGLIN-C
Descriptor:THERMITASE, EGLIN C, CALCIUM ION, ...
Authors:Gros, P., Dijkstra, B.W., Hol, W.G.J.
Deposit date:1989-05-24
Release date:1989-10-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystallographic refinement by incorporation of molecular dynamics: thermostable serine protease thermitase complexed with eglin c.
Acta Crystallogr.,Sect.B, 45, 1989
2TEC
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MOLECULAR DYNAMICS REFINEMENT OF A THERMITASE-EGLIN-C COMPLEX AT 1.98 ANGSTROMS RESOLUTION AND COMPARISON OF TWO CRYSTAL FORMS THAT DIFFER IN CALCIUM CONTENT
Descriptor:THERMITASE, EGLIN C, CALCIUM ION
Authors:Gros, P., Betzel, C., Dauter, Z., Wilson, K.S., Hol, W.G.J.
Deposit date:1990-10-26
Release date:1992-01-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Molecular dynamics refinement of a thermitase-eglin-c complex at 1.98 A resolution and comparison of two crystal forms that differ in calcium content.
J.Mol.Biol., 210, 1989
6H15
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STRUCTURE OF LRP6 P3E3P4E4 IN COMPLEX WITH VHH L-P2-B10
Descriptor:Low-density lipoprotein receptor-related protein 6, VHH L-P2-B10, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Gros, P., van Scherpenzeel, R.C.
Deposit date:2018-07-11
Release date:2019-01-30
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Anti-LRP5/6 VHHs promote differentiation of Wnt-hypersensitive intestinal stem cells.
Nat Commun, 10, 2019
6H16
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STRUCTURE OF LRP6 P3E3P4E4 IN COMPLEX WITH VHH L-P2-D07
Descriptor:Low-density lipoprotein receptor-related protein 6, VHH L-P2-D07, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Gros, P., van Scherpenzeel, R.C.
Deposit date:2018-07-11
Release date:2019-01-30
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Anti-LRP5/6 VHHs promote differentiation of Wnt-hypersensitive intestinal stem cells.
Nat Commun, 10, 2019
2MPA
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BACTERICIDAL ANTIBODY AGAINST NEISSERIA MENINGITIDIS
Descriptor:MN12H2 IGG2A-KAPPA, light chain, MN12H2 IGG2A-KAPPA,heavy chain, ...
Authors:Van Den Elsen, J.M.H., Herron, J.N., Kroon, J., Gros, P.
Deposit date:1999-06-09
Release date:1999-06-23
Last modified:2017-05-31
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Bactericidal antibody recognition of a PorA epitope of Neisseria meningitidis: crystal structure of a Fab fragment in complex with a fluorescein-conjugated peptide.
Proteins, 29, 1997
1FE8
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CRYSTAL STRUCTURE OF THE VON WILLEBRAND FACTOR A3 DOMAIN IN COMPLEX WITH A FAB FRAGMENT OF IGG RU5 THAT INHIBITS COLLAGEN BINDING
Descriptor:VON WILLEBRAND FACTOR, IMMUNOGLOBULIN IGG RU5, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Bouma, B., Huizinga, E.G., Schiphorst, M.E., Sixma, J.J., Kroon, J., Gros, P.
Deposit date:2000-07-21
Release date:2001-04-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Identification of the collagen-binding site of the von Willebrand factor A3-domain.
J.Biol.Chem., 276, 2001
1UYN
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TRANSLOCATOR DOMAIN OF AUTOTRANSPORTER NALP FROM NEISSERIA MENINGITIDIS
Descriptor:NALP, PENTAETHYLENE GLYCOL MONODECYL ETHER, SULFATE ION
Authors:Oomen, C.J., Van Ulsen, P., Van Gelder, P., Feijen, M., Tommassen, J., Gros, P.
Deposit date:2004-03-02
Release date:2004-03-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of the Translocator Domain of a Bacterial Autotransporter
Embo J., 23, 2004
1UYO
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TRANSLOCATOR DOMAIN OF AUTOTRANSPORTER NALP FROM NEISSERIA MENINGITIDIS
Descriptor:NALP, PENTAETHYLENE GLYCOL MONODECYL ETHER
Authors:Oomen, C.J., Van Ulsen, P., Van Gelder, P., Feijen, M., Tommassen, J., Gros, P.
Deposit date:2004-03-02
Release date:2004-03-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structure of the Translocator Domain of a Bacterial Autotransporter
Embo J., 23, 2004
2BRR
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COMPLEX OF THE NEISSERIAL PORA P1.4 EPITOPE PEPTIDE AND TWO FAB- FRAGMENTS (ANTIBODY MN20B9.34)
Descriptor:MN20B9.34 ANTI-P1.4 ANTIBODY, FAB HEAVY CHAIN, FAB LIGHT CHAIN, ...
Authors:Oomen, C.J., Hoogerhout, P., Kuipers, B., Vidarsson, G., Van Alphen, L., Gros, P.
Deposit date:2005-05-11
Release date:2005-07-27
Last modified:2012-05-16
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal Structure of an Anti-Meningococcal Subtype P1.4 Pora Antibody Provides Basis for Peptide- Vaccine Design.
J.Mol.Biol., 351, 2005
2ERV
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CRYSTAL STRUCTURE OF THE OUTER MEMBRANE ENZYME PAGL
Descriptor:hypothetical protein Paer03002360, CALCIUM ION, PENTAETHYLENE GLYCOL MONODECYL ETHER
Authors:Rutten, L., Geurtsen, J., Lambert, W., Smolenaers, J.J., Bonvin, A.M., van der Ley, P., Egmond, M.R., Gros, P., Tommassen, J.
Deposit date:2005-10-25
Release date:2006-04-11
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure and catalytic mechanism of the LPS 3-O-deacylase PagL from Pseudomonas aeruginosa.
Proc.Natl.Acad.Sci.USA, 103, 2006
1MPA
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BACTERICIDAL ANTIBODY AGAINST NEISSERIA MENINGITIDIS
Descriptor:MN12H2 IGG2A-KAPPA, PORA P1.16 PEPTIDE FLUORESCEIN CONJUGATE, CADMIUM ION
Authors:Van Den Elsen, J.M.H., Herron, J.N., Kroon, J., Gros, P.
Deposit date:1997-02-26
Release date:1997-09-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Bactericidal antibody recognition of a PorA epitope of Neisseria meningitidis: crystal structure of a Fab fragment in complex with a fluorescein-conjugated peptide.
Proteins, 29, 1997
4A5W
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CRYSTAL STRUCTURE OF C5B6
Descriptor:COMPLEMENT C5, COMPLEMENT COMPONENT C6, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Hadders, M.A., Bubeck, D., Forneris, F., Pangburn, M., Llorca, O., Lea, S.M., Gros, P.
Deposit date:2011-10-28
Release date:2012-03-14
Last modified:2012-10-31
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Assembly and Regulation of the Membrane Attack Complex Based on Structures of C5B6 and Sc5B9.
Cell Rep., 1, 2012
5FO7
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CRYSTAL STRUCTURE OF HUMAN COMPLEMENT C3B AT 2.8 ANGSTROM RESOLUTION
Descriptor:COMPLEMENT C3 BETA CHAIN, COMPLEMENT C3B ALPHA' CHAIN, N-ACETYL-D-GLUCOSAMINE
Authors:Forneris, F., Wu, J., Xue, X., Gros, P.
Deposit date:2015-11-18
Release date:2016-04-06
Last modified:2016-06-01
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Regulators of Complement Activity Mediate Inhibitory Mechanisms Through a Common C3B-Binding Mode.
Embo J., 35, 2016
5FO8
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CRYSTAL STRUCTURE OF HUMAN COMPLEMENT C3B IN COMPLEX WITH MCP (CCP1-4)
Descriptor:COMPLEMENT C3, MEMBRANE COFACTOR PROTEIN, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Forneris, F., Wu, J., Xue, X., Gros, P.
Deposit date:2015-11-18
Release date:2016-04-06
Last modified:2016-06-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Regulators of Complement Activity Mediate Inhibitory Mechanisms Through a Common C3B-Binding Mode.
Embo J., 35, 2016
5FO9
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CRYSTAL STRUCTURE OF HUMAN COMPLEMENT C3B IN COMPLEX WITH CR1 (CCP15- 17)
Descriptor:COMPLEMENT C3 BETA CHAIN, COMPLEMENT C3B ALPHA' CHAIN, COMPLEMENT RECEPTOR TYPE 1, ...
Authors:Forneris, F., Wu, J., Xue, X., Gros, P.
Deposit date:2015-11-18
Release date:2016-04-06
Last modified:2016-06-01
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Regulators of Complement Activity Mediate Inhibitory Mechanisms Through a Common C3B-Binding Mode.
Embo J., 35, 2016
5FOA
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CRYSTAL STRUCTURE OF HUMAN COMPLEMENT C3B IN COMPLEX WITH DAF (CCP2-4)
Descriptor:COMPLEMENT C3 BETA CHAIN, COMPLEMENT C3B ALPHA CHAIN, DECAY ACCELERATING FACTOR, ...
Authors:Forneris, F., Wu, J., Xue, X., Gros, P.
Deposit date:2015-11-18
Release date:2016-04-06
Last modified:2016-06-01
Method:X-RAY DIFFRACTION (4.188 Å)
Cite:Regulators of Complement Activity Mediate Inhibitory Mechanisms Through a Common C3B-Binding Mode.
Embo J., 35, 2016
5FOB
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CRYSTAL STRUCTURE OF HUMAN COMPLEMENT C3B IN COMPLEX WITH SMALLPOX INHIBITOR OF COMPLEMENT (SPICE)
Descriptor:COMPLEMENT C3 BETA CHAIN, COMPLEMENT C3B ALPHA' CHAIN, SMALLPOX INHIBITOR OF COMPLEMENT SPICE, ...
Authors:Forneris, F., Wu, J., Xue, X., Gros, P.
Deposit date:2015-11-18
Release date:2016-04-06
Last modified:2016-06-01
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Regulators of Complement Activity Mediate Inhibitory Mechanisms Through a Common C3B-Binding Mode.
Embo J., 35, 2016
5O32
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THE STRUCTURE OF COMPLEMENT COMPLEX
Descriptor:Complement C3, Complement factor H,Complement factor H, Complement factor I, ...
Authors:Xue, X., Wu, J., Forneris, F., Gros, P.
Deposit date:2017-05-23
Release date:2017-06-28
Last modified:2017-08-16
Method:X-RAY DIFFRACTION (4.206209 Å)
Cite:Regulator-dependent mechanisms of C3b processing by factor I allow differentiation of immune responses.
Nat. Struct. Mol. Biol., 24, 2017
5O35
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STRUCTURE OF COMPLEMENT PROTEINS COMPLEX
Descriptor:Complement C3, Complement factor H,Complement factor H, N-ACETYL-D-GLUCOSAMINE
Authors:Xue, X., Wu, J., Forneris, F., Gros, P.
Deposit date:2017-05-23
Release date:2017-06-28
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (4.2 Å)
Cite:Regulator-dependent mechanisms of C3b processing by factor I allow differentiation of immune responses.
Nat. Struct. Mol. Biol., 24, 2017
1M0U
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CRYSTAL STRUCTURE OF THE DROSOPHILA GLUTATHIONE S-TRANSFERASE-2 IN COMPLEX WITH GLUTATHIONE
Descriptor:GST2 gene product, SULFATE ION, GLUTATHIONE
Authors:Agianian, B., Tucker, P.A., Schouten, A., Leonard, K., Bullard, B., Gros, P.
Deposit date:2002-06-14
Release date:2003-02-11
Last modified:2012-03-21
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structure of a Drosophila Sigma Class Glutathione S-transferase Reveals a Novel Active Site Topography Suited for Lipid Peroxidation Products
J.Mol.Biol., 326, 2003
1ATZ
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HUMAN VON WILLEBRAND FACTOR A3 DOMAIN
Descriptor:VON WILLEBRAND FACTOR
Authors:Huizinga, E.G., Gros, P.
Deposit date:1997-08-15
Release date:1998-02-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of the A3 domain of human von Willebrand factor: implications for collagen binding.
Structure, 5, 1997
1I78
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CRYSTAL STRUCTURE OF OUTER MEMBRANE PROTEASE OMPT FROM ESCHERICHIA COLI
Descriptor:PROTEASE VII, B-OCTYLGLUCOSIDE, (4S)-2-METHYL-2,4-PENTANEDIOL
Authors:Vandeputte-Rutten, L., Kramer, R.A., Kroon, J., Dekker, N., Egmond, M.R., Gros, P.
Deposit date:2001-03-08
Release date:2001-10-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of the outer membrane protease OmpT from Escherichia coli suggests a novel catalytic site.
EMBO J., 20, 2001
1I8N
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CRYSTAL STRUCTURE OF LEECH ANTI-PLATELET PROTEIN
Descriptor:ANTI-PLATELET PROTEIN, PROPIONAMIDE
Authors:Huizinga, E.G., Schouten, A., Connolly, T.M., Kroon, J., Sixma, J.J., Gros, P.
Deposit date:2001-03-15
Release date:2001-08-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The structure of leech anti-platelet protein, an inhibitor of haemostasis.
Acta Crystallogr.,Sect.D, 57, 2001
1KCM
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CRYSTAL STRUCTURE OF MOUSE PITP ALPHA VOID OF BOUND PHOSPHOLIPID AT 2.0 ANGSTROMS RESOLUTION
Descriptor:Phosphatidylinositol Transfer Protein alpha
Authors:Schouten, A., Agianian, B., Westerman, J., Kroon, J., Wirtz, K.W.A., Gros, P.
Deposit date:2001-11-09
Release date:2002-05-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of apo-phosphatidylinositol transfer protein alpha provides insight into membrane association.
EMBO J., 21, 2002