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6HV8
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BU of 6hv8 by Molmil
Cryo-EM structure of S. cerevisiae Polymerase epsilon deltacat mutant
Descriptor: DNA polymerase epsilon catalytic subunit A, DNA polymerase epsilon subunit B, ZINC ION
Authors:Goswami, P, Purkiss, A, Cheung, A, Costa, A.
Deposit date:2018-10-10
Release date:2018-12-12
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Structure of DNA-CMG-Pol epsilon elucidates the roles of the non-catalytic polymerase modules in the eukaryotic replisome.
Nat Commun, 9, 2018
6QM8
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BU of 6qm8 by Molmil
Leishmania tarentolae proteasome 20S subunit apo structure
Descriptor: Proteasome alpha1 chain, Proteasome alpha2 chain, Proteasome alpha3 chain, ...
Authors:Rowland, P, Goswami, P.
Deposit date:2019-02-01
Release date:2019-04-17
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Preclinical candidate for the treatment of visceral leishmaniasis that acts through proteasome inhibition.
Proc.Natl.Acad.Sci.USA, 116, 2019
6QM7
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BU of 6qm7 by Molmil
Leishmania tarentolae proteasome 20S subunit complexed with GSK3494245
Descriptor: Proteasome alpha1 chain, Proteasome alpha2 chain, Proteasome alpha3 chain, ...
Authors:Rowland, P, Goswami, P.
Deposit date:2019-02-01
Release date:2019-04-17
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Preclinical candidate for the treatment of visceral leishmaniasis that acts through proteasome inhibition.
Proc.Natl.Acad.Sci.USA, 116, 2019
2IWV
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BU of 2iwv by Molmil
Structure of the monomeric outer membrane porin OmpG in the open and closed conformation
Descriptor: CALCIUM ION, LAURYL DIMETHYLAMINE-N-OXIDE, OUTER MEMBRANE PROTEIN G, ...
Authors:Yildiz, O, Vinothkumar, K.R, Goswami, P, Kuehlbrandt, W.
Deposit date:2006-07-04
Release date:2006-08-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of the Monomeric Outer-Membrane Porin Ompg in the Open and Closed Conformation.
Embo J., 25, 2006
2IWW
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BU of 2iww by Molmil
Structure of the monomeric outer membrane porin OmpG in the open and closed conformation
Descriptor: LAURYL DIMETHYLAMINE-N-OXIDE, OUTER MEMBRANE PROTEIN G, beta-D-glucopyranose, ...
Authors:Yildiz, O, Vinothkumar, K.R, Goswami, P, Kuehlbrandt, W.
Deposit date:2006-07-05
Release date:2006-08-14
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of the Monomeric Outer-Membrane Porin Ompg in the Open and Closed Conformation.
Embo J., 25, 2006
6HV9
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BU of 6hv9 by Molmil
S. cerevisiae CMG-Pol epsilon-DNA
Descriptor: Cell division control protein 45, DNA (5'-D(*GP*CP*AP*GP*CP*CP*AP*CP*GP*CP*TP*GP*GP*CP*CP*GP*TP*TP*TP*TP*A)-3'), DNA (5'-D(P*TP*AP*AP*AP*AP*CP*GP*GP*CP*CP*AP*GP*CP*GP*TP*GP*GP*CP*TP*GP*C)-3'), ...
Authors:Abid Ali, F, Purkiss, A.G, Cheung, A, Costa, A.
Deposit date:2018-10-10
Release date:2018-12-12
Last modified:2023-07-05
Method:ELECTRON MICROSCOPY (4.98 Å)
Cite:Structure of DNA-CMG-Pol epsilon elucidates the roles of the non-catalytic polymerase modules in the eukaryotic replisome.
Nat Commun, 9, 2018
8OLU
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BU of 8olu by Molmil
Leishmania tarentolae proteasome 20S subunit in complex with 1-Benzyl-N-(3-(cyclopropylcarbamoyl)phenyl)-6-oxo-1,6-dihydropyridazine-3-carboxamide
Descriptor: Proteasome alpha 1 subunit, putative, Proteasome alpha 5 subunit, ...
Authors:Rowland, P.
Deposit date:2023-03-30
Release date:2023-08-09
Last modified:2023-08-23
Method:ELECTRON MICROSCOPY (2.59 Å)
Cite:Structure-Guided Design and Synthesis of a Pyridazinone Series of Trypanosoma cruzi Proteasome Inhibitors.
J.Med.Chem., 66, 2023

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