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4Q95
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BU of 4q95 by Molmil
Crystal structure of HRASLS3/LRAT chimeric protein
Descriptor: HEPTANOIC ACID, HRAS-like suppressor 3, Lecithin retinol acyltransferase
Authors:Golczak, M, Kiser, P.D, Sears, A.E, Palczewski, K.
Deposit date:2014-04-29
Release date:2014-10-29
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:LRAT-specific domain facilitates vitamin A metabolism by domain swapping in HRASLS3.
Nat.Chem.Biol., 11, 2015
3KVC
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BU of 3kvc by Molmil
Crystal structure of bovine RPE65 at 1.9 angstrom resolution
Descriptor: FE (II) ION, Retinoid isomerohydrolase
Authors:Kiser, P.D, Lodowski, D.T, Golczak, M, Palczewski, K.
Deposit date:2009-11-29
Release date:2010-02-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Importance of membrane structural integrity for RPE65 retinoid isomerization activity.
J.Biol.Chem., 285, 2010
5HBS
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BU of 5hbs by Molmil
Crystal structure of human cellular retinol binding protein 1 in complex with all-trans-retinol at 0.89 angstrom.
Descriptor: RETINOL, Retinol-binding protein 1
Authors:Golczak, M, Arne, J.M, Silvaroli, J.A, Kiser, P.D, Banerjee, S.
Deposit date:2016-01-02
Release date:2016-03-02
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (0.89 Å)
Cite:Ligand Binding Induces Conformational Changes in Human Cellular Retinol-binding Protein 1 (CRBP1) Revealed by Atomic Resolution Crystal Structures.
J.Biol.Chem., 291, 2016
5HA1
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BU of 5ha1 by Molmil
Crystal structure of human cellular retinol binding protein 1 in complex with retinylamine
Descriptor: (2~{E},4~{E},6~{E},8~{E})-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraen-1-amine, Retinol-binding protein 1
Authors:Golczak, M, Arne, J.M, Silvaroli, J.A, Kiser, P.D, Banerjee, S.
Deposit date:2015-12-29
Release date:2016-03-02
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Ligand Binding Induces Conformational Changes in Human Cellular Retinol-binding Protein 1 (CRBP1) Revealed by Atomic Resolution Crystal Structures.
J.Biol.Chem., 291, 2016
5H9A
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BU of 5h9a by Molmil
Crystal structure of the Apo form of human cellular retinol binding protein 1
Descriptor: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Retinol-binding protein 1
Authors:Golczak, M, Arne, J.M, Silvaroli, J.A, Kiser, P.D, Banerjee, S.
Deposit date:2015-12-26
Release date:2016-03-02
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.381 Å)
Cite:Ligand Binding Induces Conformational Changes in Human Cellular Retinol-binding Protein 1 (CRBP1) Revealed by Atomic Resolution Crystal Structures.
J.Biol.Chem., 291, 2016
5H8T
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BU of 5h8t by Molmil
Crystal structure of human cellular retinol binding protein 1 in complex with all-trans-retinol
Descriptor: RETINOL, Retinol-binding protein 1
Authors:Golczak, M, Arne, J.M, Silvaroli, J.A, Kiser, P.D, Banerjee, S.
Deposit date:2015-12-23
Release date:2016-03-02
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.21 Å)
Cite:Ligand Binding Induces Conformational Changes in Human Cellular Retinol-binding Protein 1 (CRBP1) Revealed by Atomic Resolution Crystal Structures.
J.Biol.Chem., 291, 2016
4DPZ
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BU of 4dpz by Molmil
Crystal structure of human HRASLS2
Descriptor: HRAS-like suppressor 2
Authors:Kiser, P.D, Golczak, M, Sears, A.E, Lodowski, D.T, Palczewski, K.
Deposit date:2012-02-14
Release date:2012-05-30
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Structural Basis for the Acyltransferase Activity of Lecithin:Retinol Acyltransferase-like Proteins.
J.Biol.Chem., 287, 2012
4DOT
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BU of 4dot by Molmil
Crystal structure of human HRASLS3.
Descriptor: Group XVI phospholipase A2
Authors:Kiser, P.D, Golczak, M, Sears, A.E, Lodowski, D.T, Palczewski, K.
Deposit date:2012-02-10
Release date:2012-05-30
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Structural Basis for the Acyltransferase Activity of Lecithin:Retinol Acyltransferase-like Proteins.
J.Biol.Chem., 287, 2012
6AT8
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BU of 6at8 by Molmil
1.1 Angstrom Resolution Structure of Human Cellular Retinol-Binding Protein IV
Descriptor: DI(HYDROXYETHYL)ETHER, GLYCEROL, Retinoid-binding protein 7
Authors:Silvaroli, J.A, Pleshinger, M.J, Kiser, P.D, Golczak, M.
Deposit date:2017-08-28
Release date:2017-09-06
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.105 Å)
Cite:1.1 Angstrom Resolution Structure of Human Cellular Retinol-Binding Protein IV
To Be Published
7JVG
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BU of 7jvg by Molmil
Cellular retinol-binding protein 2 (CRBP2) in complex with 1-arachidonoylglycerol
Descriptor: (2S)-2,3-dihydroxypropyl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate, Retinol-binding protein 2
Authors:Silvaroli, J.A, Golczak, M.
Deposit date:2020-08-21
Release date:2021-03-10
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Molecular basis for the interaction of cellular retinol binding protein 2 (CRBP2) with nonretinoid ligands.
J.Lipid Res., 62, 2021
7RLU
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BU of 7rlu by Molmil
Structure of ALDH1L1 (10-formyltetrahydrofolate dehydrogenase) in complex with NADP
Descriptor: 4'-PHOSPHOPANTETHEINE, Cytosolic 10-formyltetrahydrofolate dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Tsybovsky, Y, Sereda, V, Golczak, M, Krupenko, N.I, Krupenko, S.A.
Deposit date:2021-07-26
Release date:2022-01-12
Last modified:2022-02-02
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structure of putative tumor suppressor ALDH1L1.
Commun Biol, 5, 2022
7RLT
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BU of 7rlt by Molmil
Structure of ligand-free ALDH1L1 (10-formyltetrahydrofolate dehydrogenase)
Descriptor: 4'-PHOSPHOPANTETHEINE, Cytosolic 10-formyltetrahydrofolate dehydrogenase
Authors:Tsybovsky, Y, Sereda, V, Golczak, M, Krupenko, N.I, Krupenko, S.A.
Deposit date:2021-07-26
Release date:2022-01-12
Last modified:2022-02-02
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structure of putative tumor suppressor ALDH1L1.
Commun Biol, 5, 2022
5VGL
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BU of 5vgl by Molmil
Crystal structure of lachrymatory factor synthase from Allium cepa
Descriptor: Lachrymatory-factor synthase
Authors:Silvaroli, J.A, Pleshinger, M.J, Banerjee, S, Kiser, P.D, Golczak, M.
Deposit date:2017-04-11
Release date:2017-07-26
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Enzyme That Makes You Cry-Crystal Structure of Lachrymatory Factor Synthase from Allium cepa.
ACS Chem. Biol., 12, 2017
5VGS
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BU of 5vgs by Molmil
Crystal structure of lachrymatory factor synthase from Allium cepa in complex with crotyl alcohol
Descriptor: (2E)-but-2-en-1-ol, (2Z)-but-2-en-1-ol, Lachrymatory-factor synthase
Authors:Silvaroli, J.A, Pleshinger, M.J, Banerjee, S, Kiser, P.D, Golczak, M.
Deposit date:2017-04-11
Release date:2017-07-26
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Enzyme That Makes You Cry-Crystal Structure of Lachrymatory Factor Synthase from Allium cepa.
ACS Chem. Biol., 12, 2017
8GEV
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BU of 8gev by Molmil
Crystal structure of human cellular retinol binding protein 1 in complex with 1-{[3-(diphenylmethyl)-1,2,4-oxadiazol-5-yl]methyl}-4-(methoxymethyl)piperidine
Descriptor: 1-{[3-(diphenylmethyl)-1,2,4-oxadiazol-5-yl]methyl}-4-(methoxymethyl)piperidine, Retinol-binding protein 1
Authors:Plau, J, Golczak, M.
Deposit date:2023-03-07
Release date:2023-10-04
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Discovery of Nonretinoid Inhibitors of CRBP1: Structural and Dynamic Insights for Ligand-Binding Mechanisms.
Acs Chem.Biol., 18, 2023
8GD2
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BU of 8gd2 by Molmil
Crystal structure of human cellular retinol binding protein 1 in complex with N-methyl-1-{3-[1-(4-methylphenyl)cyclopentyl]-1,2,4-oxadiazol-5-yl}-N-(2-thienylmethyl)methanamine
Descriptor: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, N-methyl-1-{3-[1-(4-methylphenyl)cyclopentyl]-1,2,4-oxadiazol-5-yl}-N-[(thiophen-2-yl)methyl]methanamine, Retinol-binding protein 1
Authors:Plau, J, Golczak, M.
Deposit date:2023-03-03
Release date:2023-10-04
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.13 Å)
Cite:Discovery of Nonretinoid Inhibitors of CRBP1: Structural and Dynamic Insights for Ligand-Binding Mechanisms.
Acs Chem.Biol., 18, 2023
8GEM
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BU of 8gem by Molmil
Crystal structure of human cellular retinol binding protein 1 in complex with N-ethyl-N-({3-[1-(4-methylphenyl)cyclopentyl]-1,2,4-oxadiazol-5-yl}methyl)-2-(1H-pyrazol-1-yl)ethanamine
Descriptor: N-ethyl-N-({3-[1-(4-methylphenyl)cyclopentyl]-1,2,4-oxadiazol-5-yl}methyl)-2-(1H-pyrazol-1-yl)ethan-1-amine, Retinol-binding protein 1
Authors:Plau, J, Golczak, M.
Deposit date:2023-03-07
Release date:2023-10-04
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Discovery of Nonretinoid Inhibitors of CRBP1: Structural and Dynamic Insights for Ligand-Binding Mechanisms.
Acs Chem.Biol., 18, 2023
8GDM
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BU of 8gdm by Molmil
Crystal structure of human cellular retinol binding protein 1 in complex with {[3-(diphenylmethyl)-1,2,4-oxadiazol-5-yl]methyl}(methyl)[1-(thiophen-2-yl)ethyl]amine
Descriptor: (1S)-N-{[3-(diphenylmethyl)-1,2,4-oxadiazol-5-yl]methyl}-N-methyl-1-(thiophen-2-yl)ethan-1-amine, Retinol-binding protein 1
Authors:Plau, J, Golczak, M.
Deposit date:2023-03-06
Release date:2023-10-04
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Discovery of Nonretinoid Inhibitors of CRBP1: Structural and Dynamic Insights for Ligand-Binding Mechanisms.
Acs Chem.Biol., 18, 2023
8GEU
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BU of 8geu by Molmil
Crystal structure of human cellular retinol binding protein 1 in complex with methyl({3-[1-(4-methylphenyl)cyclopentyl]-1,2,4-oxadiazol-5-yl}methyl)[(1-methylpyrazol-4-yl)methyl]amine
Descriptor: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, N-methyl-1-{3-[1-(4-methylphenyl)cyclopentyl]-1,2,4-oxadiazol-5-yl}-N-[(1-methyl-1H-pyrazol-4-yl)methyl]methanamine, Retinol-binding protein 1
Authors:Plau, J, Golczak, M.
Deposit date:2023-03-07
Release date:2023-10-11
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:Discovery of Nonretinoid Inhibitors of CRBP1: Structural and Dynamic Insights for Ligand-Binding Mechanisms.
Acs Chem.Biol., 18, 2023
8GEY
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BU of 8gey by Molmil
Crystal structure of human cellular retinol binding protein 1 in complex with 4-(hydroxymethyl)-1-[(4-methoxy-5,6,7,8-tetrahydronaphthalen-1-yl)sulfonyl]piperidin-4-ol
Descriptor: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4-(hydroxymethyl)-1-(4-methoxy-5,6,7,8-tetrahydronaphthalene-1-sulfonyl)piperidin-4-ol, Retinol-binding protein 1
Authors:Plau, J, Golczak, M.
Deposit date:2023-03-07
Release date:2023-10-04
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Discovery of Nonretinoid Inhibitors of CRBP1: Structural and Dynamic Insights for Ligand-Binding Mechanisms.
Acs Chem.Biol., 18, 2023
4CIZ
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BU of 4ciz by Molmil
Crystal structure of the complex of the Cellular Retinal Binding Protein with 9-cis-retinal
Descriptor: L(+)-TARTARIC ACID, RETINAL, RETINALDEHYDE-BINDING PROTEIN 1
Authors:Bolze, C.S, Helbling, R.E, Owen, R.L, Pearson, A.R, Pompidor, G, Dworkowski, F, Fuchs, M.R, Furrer, J, Golczak, M, Palczewski, K, Cascella, M, Stocker, A.
Deposit date:2013-12-18
Release date:2014-01-08
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.403 Å)
Cite:Human Cellular Retinaldehyde-Binding Protein Has Secondary Thermal 9-Cis-Retinal Isomerase Activity.
J.Am.Chem.Soc., 136, 2014
4CJ6
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BU of 4cj6 by Molmil
Crystal structure of the complex of the Cellular Retinal Binding Protein Mutant R234W with 9-cis-retinal
Descriptor: RETINAL, RETINALDEHYDE-BINDING PROTEIN 1
Authors:Bolze, C.S, Helbling, R.E, Owen, R.L, Pearson, A.R, Pompidor, G, Dworkowski, F, Fuchs, M.R, Furrer, J, Golczak, M, Palczewski, K, Cascella, M, Stocker, A.
Deposit date:2013-12-19
Release date:2014-01-08
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.896 Å)
Cite:Human Cellular Retinaldehyde-Binding Protein Has Secondary Thermal 9-Cis-Retinal Isomerase Activity.
J.Am.Chem.Soc., 136, 2014
7JWR
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BU of 7jwr by Molmil
Cellular retinol-binding protein 2 (CRBP2) in complex with 2-oleoylglycerol
Descriptor: 1,3-dihydroxypropan-2-yl (9Z)-octadec-9-enoate, Retinol-binding protein 2
Authors:Silvaroli, J.A, Banarjee, S, Golczak, M.
Deposit date:2020-08-26
Release date:2021-03-10
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.30000067 Å)
Cite:Molecular basis for the interaction of cellular retinol binding protein 2 (CRBP2) with nonretinoid ligands.
J.Lipid Res., 62, 2021
7JWD
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BU of 7jwd by Molmil
Cellular retinol-binding protein 2 (CRBP2) in complex with 2-linoleoylglycerol
Descriptor: 1,3-dihydroxypropan-2-yl (9Z,12Z)-octadeca-9,12-dienoate, Retinol-binding protein 2
Authors:Silvaroli, J.A, Banarjee, S, Golczak, M.
Deposit date:2020-08-25
Release date:2021-03-10
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.35000193 Å)
Cite:Molecular basis for the interaction of cellular retinol binding protein 2 (CRBP2) with nonretinoid ligands.
J.Lipid Res., 62, 2021
7K3I
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BU of 7k3i by Molmil
Cellular retinol-binding protein 2 (CRBP2) in complex with 2-lauroylglycerol
Descriptor: 1,3-dihydroxypropan-2-yl dodecanoate, Retinol-binding protein 2
Authors:Adams, C, Silvaroli, J.A, Banarjee, S, Golczak, M.
Deposit date:2020-09-11
Release date:2021-03-10
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Molecular basis for the interaction of cellular retinol binding protein 2 (CRBP2) with nonretinoid ligands.
J.Lipid Res., 62, 2021

 

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