Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
6EZU
DownloadVisualize
BU of 6ezu by Molmil
Schistosoma mansoni Phosphodiesterase 4A
Descriptor: ADENOSINE MONOPHOSPHATE, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, MAGNESIUM ION, ...
Authors:Brown, D.G, Schroeder, S, Gil, C.
Deposit date:2017-11-16
Release date:2018-12-12
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:The structure of Schistosoma mansoni Phosphodiesterase 4A in complex with cAMP
To Be Published
6FG5
DownloadVisualize
BU of 6fg5 by Molmil
Schistosoma mansoni Phosphodiesterase 4A
Descriptor: MAGNESIUM ION, Phosphodiesterase, ZINC ION
Authors:Brown, D.G, Schroeder, S, Gil, C.
Deposit date:2018-01-10
Release date:2019-01-30
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:The structure of Schistosoma mansoni Phosphodiesterase 4A
To Be Published
7QDG
DownloadVisualize
BU of 7qdg by Molmil
SARS-CoV-2 S protein S:A222V + S:D614G mutant 1-up
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Ginex, T, Marco-Marin, C, Wieczor, M, Mata, C.P, Krieger, J, Lopez-Redondo, M.L, Frances-Gomez, C, Ruiz-Rodriguez, P, Melero, R, Sanchez-Sorzano, C.O, Martinez, M, Gougeard, N, Forcada-Nadal, A, Zamora-Caballero, S, Gozalbo-Rovira, R, Sanz-Frasquet, C, Bravo, J, Rubio, V, Marina, A, Geller, R, Comas, I, Gil, C, Coscolla, M, Orozco, M, LLacer, J.L, Carazo, J.M.
Deposit date:2021-11-27
Release date:2022-05-25
Last modified:2022-08-24
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:The structural role of SARS-CoV-2 genetic background in the emergence and success of spike mutations: The case of the spike A222V mutation.
Plos Pathog., 18, 2022
7QDH
DownloadVisualize
BU of 7qdh by Molmil
SARS-CoV-2 S protein S:D614G mutant 1-up
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein,Fibritin
Authors:Ginex, T, Marco-Marin, C, Wieczor, M, Mata, C.P, Krieger, J, Lopez-Redondo, M.L, Frances-Gomez, C, Ruiz-Rodriguez, P, Melero, R, Sanchez-Sorzano, C.O, Martinez, M, Gougeard, N, Forcada-Nadal, A, Zamora-Caballero, S, Gozalbo-Rovira, R, Sanz-Frasquet, C, Bravo, J, Rubio, V, Marina, A, Geller, R, Comas, I, Gil, C, Coscolla, M, Orozco, M, LLacer, J.L, Carazo, J.M.
Deposit date:2021-11-27
Release date:2022-05-25
Last modified:2022-08-10
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:The structural role of SARS-CoV-2 genetic background in the emergence and success of spike mutations: The case of the spike A222V mutation.
Plos Pathog., 18, 2022
3G3N
DownloadVisualize
BU of 3g3n by Molmil
PDE7A catalytic domain in complex with 3-(2,6-difluorophenyl)-2-(methylthio)quinazolin-4(3H)-one
Descriptor: 3-(2,6-difluorophenyl)-2-(methylthio)quinazolin-4(3H)-one, High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A, MAGNESIUM ION, ...
Authors:Castano, T, Wang, H.
Deposit date:2009-02-02
Release date:2009-04-28
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Synthesis, structural analysis, and biological evaluation of thioxoquinazoline derivatives as phosphodiesterase 7 inhibitors
Chemmedchem, 4, 2009
6EPA
DownloadVisualize
BU of 6epa by Molmil
Structure of dNCS-1 bound to the NCS-1/Ric8a protein/protein interaction regulator IGS-1.76
Descriptor: 2-(2-METHOXYETHOXY)ETHANOL, CALCIUM ION, FI18190p1, ...
Authors:Sanchez-Barrena, M.J, Daniel, M, Infantes, L.
Deposit date:2017-10-11
Release date:2018-08-29
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Deciphering the Inhibition of the Neuronal Calcium Sensor 1 and the Guanine Exchange Factor Ric8a with a Small Phenothiazine Molecule for the Rational Generation of Therapeutic Synapse Function Regulators.
J. Med. Chem., 61, 2018
5G08
DownloadVisualize
BU of 5g08 by Molmil
Crystal structure of Drosophila NCS-1 bound to chlorpromazine
Descriptor: 1,2-ETHANEDIOL, 3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine, CALCIUM ION, ...
Authors:Chaves-Sanjuan, A, Infantes, L, Sanchez-Barrena, M.J.
Deposit date:2016-03-17
Release date:2017-01-25
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:Interference of the complex between NCS-1 and Ric8a with phenothiazines regulates synaptic function and is an approach for fragile X syndrome.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5FYX
DownloadVisualize
BU of 5fyx by Molmil
Crystal structure of Drosophila NCS-1 bound to penothiazine FD16
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, FREQUENIN 2, ...
Authors:Martinez-Gonzalez, L, Chaves-Sanjuan, A, Infantes, L, Sanchez-Barrena, M.J.
Deposit date:2016-03-10
Release date:2017-01-25
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Interference of the complex between NCS-1 and Ric8a with phenothiazines regulates synaptic function and is an approach for fragile X syndrome.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
7QHW
DownloadVisualize
BU of 7qhw by Molmil
TTBK1 kinase domain in complex with inhibitor 29
Descriptor: GLYCEROL, SULFATE ION, Tau-tubulin kinase 1, ...
Authors:Nozal, V, Liehta, D.
Deposit date:2021-12-14
Release date:2022-10-26
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:TDP-43 Modulation by Tau-Tubulin Kinase 1 Inhibitors: A New Avenue for Future Amyotrophic Lateral Sclerosis Therapy.
J.Med.Chem., 65, 2022
5AAN
DownloadVisualize
BU of 5aan by Molmil
Crystal structure of Drosophila NCS-1 bound to penothiazine FD44
Descriptor: 2-(2-METHOXYETHOXY)ETHANOL, CALCIUM ION, CG5907-PA, ...
Authors:Chaves-Sanjuan, A, Infantes, L, Sanchez-Barrena, M.J.
Deposit date:2015-07-27
Release date:2017-01-25
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Interference of the complex between NCS-1 and Ric8a with phenothiazines regulates synaptic function and is an approach for fragile X syndrome.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
7Q8V
DownloadVisualize
BU of 7q8v by Molmil
Crystal structure of TTBK1 in complex with VNG2.73 (compound 42)
Descriptor: PHOSPHATE ION, Tau-tubulin kinase 1, ~{N}-[4-(2-chloranylphenoxy)phenyl]-7~{H}-pyrrolo[2,3-d]pyrimidin-4-amine
Authors:Chaikuad, A, Nozal, V, Martinez, A, Knapp, S, Structural Genomics Consortium (SGC)
Deposit date:2021-11-11
Release date:2022-03-09
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:TDP-43 Modulation by Tau-Tubulin Kinase 1 Inhibitors: A New Avenue for Future Amyotrophic Lateral Sclerosis Therapy.
J.Med.Chem., 65, 2022
7Q8Y
DownloadVisualize
BU of 7q8y by Molmil
Crystal structure of TTBK2 in complex with VNG2.73 (compound 42)
Descriptor: PHOSPHATE ION, Tau-tubulin kinase 2, ~{N}-[4-(2-chloranylphenoxy)phenyl]-7~{H}-pyrrolo[2,3-d]pyrimidin-4-amine
Authors:Chaikuad, A, Nozal, V, Martinez, A, Knapp, S, Structural Genomics Consortium (SGC)
Deposit date:2021-11-11
Release date:2022-03-09
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:TDP-43 Modulation by Tau-Tubulin Kinase 1 Inhibitors: A New Avenue for Future Amyotrophic Lateral Sclerosis Therapy.
J.Med.Chem., 65, 2022
7Q8W
DownloadVisualize
BU of 7q8w by Molmil
Crystal structure of TTBK1 in complex with VNG1.35 (compound 23)
Descriptor: 1,2-ETHANEDIOL, PHOSPHATE ION, Tau-tubulin kinase 1, ...
Authors:Chaikuad, A, Nozal, V, Martinez, A, Knapp, S, Structural Genomics Consortium (SGC)
Deposit date:2021-11-11
Release date:2022-03-09
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:TDP-43 Modulation by Tau-Tubulin Kinase 1 Inhibitors: A New Avenue for Future Amyotrophic Lateral Sclerosis Therapy.
J.Med.Chem., 65, 2022
7Q90
DownloadVisualize
BU of 7q90 by Molmil
Crystal structure of TTBK2 in complex with VNG1.63 (compound 32)
Descriptor: PHOSPHATE ION, Tau-tubulin kinase 2, ~{N}-[4-(4-methoxyphenoxy)phenyl]-7~{H}-pyrrolo[2,3-d]pyrimidin-4-amine
Authors:Chaikuad, A, Nozal, V, Martinez, A, Knapp, S, Structural Genomics Consortium (SGC)
Deposit date:2021-11-11
Release date:2022-03-09
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:TDP-43 Modulation by Tau-Tubulin Kinase 1 Inhibitors: A New Avenue for Future Amyotrophic Lateral Sclerosis Therapy.
J.Med.Chem., 65, 2022
7Q8Z
DownloadVisualize
BU of 7q8z by Molmil
Crystal structure of TTBK2 in complex with VNG1.33 (compound 27)
Descriptor: PHOSPHATE ION, Tau-tubulin kinase 2, ~{N}-(4-phenoxyphenyl)-7~{H}-pyrrolo[2,3-d]pyrimidin-4-amine
Authors:Chaikuad, A, Nozal, V, Martinez, A, Knapp, S, Structural Genomics Consortium (SGC)
Deposit date:2021-11-11
Release date:2022-03-09
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:TDP-43 Modulation by Tau-Tubulin Kinase 1 Inhibitors: A New Avenue for Future Amyotrophic Lateral Sclerosis Therapy.
J.Med.Chem., 65, 2022

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon