1A6A
 
 | | THE STRUCTURE OF AN INTERMEDIATE IN CLASS II MHC MATURATION: CLIP BOUND TO HLA-DR3 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, HLA class II histocompatibility antigen, DR alpha chain, ... | | Authors: | Ghosh, P, Amaya, M, Mellins, E, Wiley, D.C. | | Deposit date: | 1998-02-22 | | Release date: | 1998-05-27 | | Last modified: | 2023-08-02 | | Method: | X-RAY DIFFRACTION (2.75 Å) | | Cite: | The structure of an intermediate in class II MHC maturation: CLIP bound to HLA-DR3.
Nature, 378, 1995
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1JYA
 | | Crystal Structure of SycE | | Descriptor: | YOPE regulator | | Authors: | Ghosh, P, Birtalan, S. | | Deposit date: | 2001-09-11 | | Release date: | 2001-10-31 | | Last modified: | 2018-01-31 | | Method: | X-RAY DIFFRACTION (1.74 Å) | | Cite: | Structure of the Yersinia type III secretory system chaperone SycE.
Nat.Struct.Biol., 8, 2001
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4DWL
 | | Avd molecule from Bordetella bacteriophage DGR | | Descriptor: | Bbp7, PHOSPHATE ION | | Authors: | Ghosh, P, Al-Ayyoubi, M. | | Deposit date: | 2012-02-24 | | Release date: | 2013-02-27 | | Last modified: | 2015-01-14 | | Method: | X-RAY DIFFRACTION (2.69 Å) | | Cite: | Structure of the essential diversity-generating retroelement protein bAvd and its functionally important interaction with reverse transcriptase.
Structure, 21, 2013
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7X7N
 | | 3D model of the 3-RBD up single trimeric spike protein of SARS-CoV2 in the presence of synthetic peptide SIH-5. | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, Synthetic peptide SIH-5 | | Authors: | Khatri, B, Pramanick, I, Malladi, S.K, Rajmani, R.S, Kumar, S, Ghosh, P, Sengupta, N, Rahisuddin, R, Kumaran, S, Ringe, R.P, Varadarajan, R, Dutta, S, Chatterjee, J. | | Deposit date: | 2022-03-10 | | Release date: | 2022-04-27 | | Last modified: | 2022-11-16 | | Method: | ELECTRON MICROSCOPY (4.47 Å) | | Cite: | A dimeric proteomimetic prevents SARS-CoV-2 infection by dimerizing the spike protein.
Nat.Chem.Biol., 18, 2022
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7SAF
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7SAY
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2XNX
 | | BC1 fragment of streptococcal M1 protein in complex with human fibrinogen | | Descriptor: | FIBRINOGEN ALPHA CHAIN, FIBRINOGEN BETA CHAIN, FIBRINOGEN GAMMA CHAIN, ... | | Authors: | Macheboeuf, P, Y Fu, C, Zinkernagel, A.S, Johnson, J.E, Nizet, V, Ghosh, P. | | Deposit date: | 2010-08-06 | | Release date: | 2011-04-13 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Streptococcal M1 Protein Constructs a Pathological Host Fibrinogen Network
Nature, 472, 2011
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2XNY
 | | A fragment of streptococcal M1 protein in complex with human fibrinogen | | Descriptor: | FIBRINOGEN ALPHA CHAIN, FIBRINOGEN BETA CHAIN, FIBRINOGEN GAMMA CHAIN, ... | | Authors: | Macheboeuf, P, Y Fu, C, Zinkernagel, A.S, Johnson, J.E, Nizet, V, Ghosh, P. | | Deposit date: | 2010-08-06 | | Release date: | 2011-04-13 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (7.5 Å) | | Cite: | Streptococcal M1 Protein Constructs a Pathological Host Fibrinogen Network
Nature, 472, 2011
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4D8M
 | | Crystal structure of Bacillus thuringiensis Cry5B nematocidal toxin | | Descriptor: | Pesticidal crystal protein cry5Ba | | Authors: | Fan, H, Hu, Y, Aroian, R.V, Ghosh, P, Berkeley Structural Genomics Center (BSGC) | | Deposit date: | 2012-01-10 | | Release date: | 2012-12-19 | | Last modified: | 2013-02-20 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structure and Glycolipid Binding Properties of the Nematicidal Protein Cry5B.
Biochemistry, 51, 2012
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4D9V
 | | Structure of the Type III Secretion System Protein | | Descriptor: | YscD; putative type III secretion protein | | Authors: | Gamez, A.M, Ghosh, P. | | Deposit date: | 2012-01-12 | | Release date: | 2012-09-26 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.519 Å) | | Cite: | Structure and interactions of the cytoplasmic domain of the Yersinia type III secretion protein YscD.
J.Bacteriol., 194, 2012
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6ORI
 | | Enterococcal surface protein, partial N-terminal region | | Descriptor: | CALCIUM ION, EF0056 | | Authors: | Spiegelman, L, Zhang, L, Tezcan, A, Ghosh, P. | | Deposit date: | 2019-04-30 | | Release date: | 2020-05-13 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Enterococcal surface protein, partial N-terminal region (CASP target)
To Be Published
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6FQ3
 | | Crystal structure of Danio rerio Lin41 filamin-NHL domains in complex with lin-29A 5'UTR 13mer RNA | | Descriptor: | CHLORIDE ION, E3 ubiquitin-protein ligase TRIM71, RNA (5'-R(*GP*GP*AP*GP*UP*CP*CP*AP*AP*CP*UP*CP*C)-3') | | Authors: | Kumari, P, Aeschimann, F, Gaidatzis, D, Keusch, J.J, Ghosh, P, Neagu, A, Pachulska-Wieczorek, K, Bujnicki, J.M, Gut, H, Grosshans, H, Ciosk, R. | | Deposit date: | 2018-02-13 | | Release date: | 2018-05-09 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.901 Å) | | Cite: | Evolutionary plasticity of the NHL domain underlies distinct solutions to RNA recognition.
Nat Commun, 9, 2018
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3N4I
 | | Crystal structure of the SHV-1 D104E beta-lactamase/beta-lactamase inhibitor protein (BLIP) complex | | Descriptor: | Beta-lactamase SHV-1, Beta-lactamase inhibitory protein | | Authors: | Hanes, M.S, Reynolds, K.A, McNamara, C, Ghosh, P, Bonomo, R.A, Kirsch, J.F, Handel, T.M. | | Deposit date: | 2010-05-21 | | Release date: | 2011-03-09 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.56 Å) | | Cite: | Specificity and Cooperativity at beta-lactamase Position 104 in TEM-1/BLIP and SHV-1/BLIP interactions
Proteins, 79, 2011
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5VF4
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6FPT
 | | Crystal structure of Danio rerio Lin41 filamin-NHL domains | | Descriptor: | E3 ubiquitin-protein ligase TRIM71 | | Authors: | Kumari, P, Aeschimann, F, Gaidatzis, D, Keusch, J.J, Ghosh, P, Neagu, A, Pachulska-Wieczorek, K, Bujnicki, J.M, Gut, H, Grosshans, H, Ciosk, R. | | Deposit date: | 2018-02-12 | | Release date: | 2018-05-09 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Evolutionary plasticity of the NHL domain underlies distinct solutions to RNA recognition.
Nat Commun, 9, 2018
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6FQL
 | | Crystal structure of Danio rerio Lin41 filamin-NHL domains in complex with mab-10 3'UTR 13mer RNA | | Descriptor: | CHLORIDE ION, E3 ubiquitin-protein ligase TRIM71, RNA (5'-R(*UP*GP*CP*AP*UP*UP*UP*AP*AP*UP*GP*CP*A)-3') | | Authors: | Kumari, P, Aeschimann, F, Gaidatzis, D, Keusch, J.J, Ghosh, P, Neagu, A, Pachulska-Wieczorek, K, Bujnicki, J.M, Gut, H, Grosshans, H, Ciosk, R. | | Deposit date: | 2018-02-14 | | Release date: | 2018-05-09 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.349 Å) | | Cite: | Evolutionary plasticity of the NHL domain underlies distinct solutions to RNA recognition.
Nat Commun, 9, 2018
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5HZP
 | | Structure of human C4b-binding protein alpha chain CCP domains 1 and 2 in complex with the hypervariable region of group A Streptococcus M49 protein. | | Descriptor: | C4b-binding protein alpha chain, M protein, serotype 49, ... | | Authors: | Buffalo, C.Z, Bahn-Suh, A.J, Ghosh, P. | | Deposit date: | 2016-02-02 | | Release date: | 2016-07-20 | | Last modified: | 2019-12-11 | | Method: | X-RAY DIFFRACTION (2.74 Å) | | Cite: | Conserved patterns hidden within group A Streptococcus M protein hypervariability recognize human C4b-binding protein.
Nat Microbiol, 1, 2016
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5HYP
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5HYT
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5HYU
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5IOO
 | | Accommodation of massive sequence variation in Nanoarchaeota by the C-type lectin fold | | Descriptor: | AvpA, MAGNESIUM ION | | Authors: | Handa, S, Paul, B, Miller, J, Valentine, D, Ghosh, P. | | Deposit date: | 2016-03-08 | | Release date: | 2016-11-09 | | Last modified: | 2019-12-11 | | Method: | X-RAY DIFFRACTION (2.521 Å) | | Cite: | Conservation of the C-type lectin fold for accommodating massive sequence variation in archaeal diversity-generating retroelements.
Bmc Struct.Biol., 16, 2016
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5I0Q
 | | Structure of human C4b-binding protein alpha chain CCP domains 1 and 2 in complex with the hypervariable region of mutant group A Streptococcus M2 (K65A, N66A) protein | | Descriptor: | C4b-binding protein alpha chain, M protein, serotype 2.1 | | Authors: | Buffalo, C.Z, Bahn-Suh, A.J, Ghosh, P. | | Deposit date: | 2016-02-04 | | Release date: | 2016-07-20 | | Last modified: | 2016-10-26 | | Method: | X-RAY DIFFRACTION (2.293 Å) | | Cite: | Conserved patterns hidden within group A Streptococcus M protein hypervariability recognize human C4b-binding protein.
Nat Microbiol, 1, 2016
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6MHE
 | | Galphai3 co-crystallized with KB752 | | Descriptor: | GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, Guanine nucleotide-binding protein G(k) subunit alpha, ... | | Authors: | Rees, S.D, Kalogriopoulos, N.A, Ngo, T, Kopcho, N, Ilatovskiy, A, Sun, N, Komives, E, Chang, G, Ghosh, P, Kufareva, I. | | Deposit date: | 2018-09-17 | | Release date: | 2019-07-31 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structural basis for GPCR-independent activation of heterotrimeric Gi proteins.
Proc.Natl.Acad.Sci.USA, 116, 2019
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6MHF
 | | Galphai3 co-crystallized with GIV/Girdin | | Descriptor: | GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, Girdin, ... | | Authors: | Rees, S.D, Kalogriopoulos, N.A, Ngo, T, Kopcho, N, Ilatovskiy, A, Sun, N, Komives, E, Chang, G, Ghosh, P, Kufareva, I. | | Deposit date: | 2018-09-17 | | Release date: | 2019-07-31 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural basis for GPCR-independent activation of heterotrimeric Gi proteins.
Proc.Natl.Acad.Sci.USA, 116, 2019
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1HQ0
 | | CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF E.COLI CYTOTOXIC NECROTIZING FACTOR TYPE 1 | | Descriptor: | CYTOTOXIC NECROTIZING FACTOR 1, PHOSPHATE ION | | Authors: | Buetow, L, Flatau, G, Chiu, K, Boquet, P, Ghosh, P. | | Deposit date: | 2000-12-13 | | Release date: | 2001-07-04 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.83 Å) | | Cite: | Structure of the Rho-activating domain of Escherichia coli cytotoxic necrotizing factor 1.
Nat.Struct.Biol., 8, 2001
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