Author results

1VPT
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AS11 VARIANT OF VACCINIA VIRUS PROTEIN VP39 IN COMPLEX WITH S-ADENOSYL-L-METHIONINE
Descriptor:VP39, S-ADENOSYLMETHIONINE
Authors:Hodel, A.E., Gershon, P.D., Shi, X., Quiocho, F.A.
Deposit date:1996-03-20
Release date:1996-08-17
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The 1.85 A structure of vaccinia protein VP39: a bifunctional enzyme that participates in the modification of both mRNA ends.
Cell(Cambridge,Mass.), 85, 1996
3OWG
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CRYSTAL STRUCTURE OF VACCINIA VIRUS POLYADENYLATE POLYMERASE(VP55)
Descriptor:Poly(A) polymerase catalytic subunit
Authors:Li, C., Li, H., Zhou, S., Gershon, P.D., Poulos, T.L.
Deposit date:2010-09-17
Release date:2011-09-21
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.86 Å)
Cite:Domain-level rocking motion within a polymerase that translocates on single-stranded nucleic acid.
Acta Crystallogr.,Sect.D, 69, 2013
1P39
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DC26 MUTANT OF VACCINIA VIRUS PROTEIN VP39 IN COMPLEX WITH S-ADENOSYLHOMOCYSTEINE AND M7G(5')PPPG
Descriptor:VP39, S-ADENOSYL-L-HOMOCYSTEINE, 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE
Authors:Hodel, A.E., Gershon, P.D., Quiocho, F.A.
Deposit date:1996-12-16
Release date:1997-09-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Specific protein recognition of an mRNA cap through its alkylated base.
Nat.Struct.Biol., 4, 1997
1V39
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DC26 MUTANT OF VACCINIA VIRUS PROTEIN VP39 IN COMPLEX WITH S-ADENOSYLHOMOCYSTEINE AND M7G(5')PPPG
Descriptor:VP39, S-ADENOSYL-L-HOMOCYSTEINE, 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE
Authors:Hodel, A.E., Gershon, P.D., Quiocho, F.A.
Deposit date:1996-12-16
Release date:1997-09-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Specific protein recognition of an mRNA cap through its alkylated base.
Nat.Struct.Biol., 4, 1997
1VP3
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VACCINIA VIRUS PROTEIN VP39 IN COMPLEX WITH S-ADENOSYLHOMOCYSTEINE
Descriptor:VP39, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Hodel, A.E., Gershon, P.D., Quiocho, F.A.
Deposit date:1996-11-21
Release date:1997-09-17
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Specific protein recognition of an mRNA cap through its alkylated base.
Nat.Struct.Biol., 4, 1997
1VP9
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DC26 MUTANT OF VACCINIA VIRUS PROTEIN VP39 IN COMPLEX WITH S-ADENOSYLHOMOCYSTEINE
Descriptor:VP39, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Hodel, A.E., Gershon, P.D., Quiocho, F.A.
Deposit date:1996-11-23
Release date:1997-09-17
Last modified:2014-02-12
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Specific protein recognition of an mRNA cap through its alkylated base.
Nat.Struct.Biol., 4, 1997
2VP3
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DC26 MUTANT OF VACCINIA VIRUS PROTEIN VP39 IN COMPLEX WITH S-ADENOSYLHOMOCYSTEINE AND M7G(5')PPPG
Descriptor:VP39, S-ADENOSYL-L-HOMOCYSTEINE, 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE
Authors:Hodel, A.E., Gershon, P.D., Quiocho, F.A.
Deposit date:1996-12-16
Release date:1997-09-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Specific protein recognition of an mRNA cap through its alkylated base.
Nat.Struct.Biol., 4, 1997
3ER8
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CRYSTAL STRUCTURE OF THE HETERODIMERIC VACCINIA VIRUS MRNA POLYADENYLATE POLYMERASE COMPLEX WITH TWO FRAGMENTS OF RNA
Descriptor:Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase, Poly(A) polymerase catalytic subunit, RNA/DNA chimera 5'-D(CP*CP*)R(UP*UP*)D(C)-3', ...
Authors:Li, C., Li, H., Zhou, S., Poulos, T.L., Gershon, P.D.
Deposit date:2008-10-01
Release date:2009-06-16
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (3.18 Å)
Cite:Polymerase Translocation with Respect to Single-Stranded Nucleic Acid: Looping or Wrapping of Primer around a Poly(A) Polymerase
Structure, 17, 2009
3ER9
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CRYSTAL STRUCTURE OF THE HETERODIMERIC VACCINIA VIRUS MRNA POLYADENYLATE POLYMERASE COMPLEX WITH UU AND 3'-DEOXY ATP
Descriptor:Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase, Poly(A) polymerase catalytic subunit, 5'-R(UP*U)-3', ...
Authors:Li, C., Li, H., Zhou, S., Poulos, T.L., Gershon, P.D.
Deposit date:2008-10-01
Release date:2009-06-16
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Polymerase Translocation with Respect to Single-Stranded Nucleic Acid: Looping or Wrapping of Primer around a Poly(A) Polymerase
Structure, 17, 2009
3ERC
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CRYSTAL STRUCTURE OF THE HETERODIMERIC VACCINIA VIRUS MRNA POLYADENYLATE POLYMERASE WITH THREE FRAGMENTS OF RNA AND 3'-DEOXY ATP
Descriptor:Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase, Poly(A) polymerase catalytic subunit, RNA/DNA chimera (5'-D(CP*)R(UP*UP*)D(CP*C)-3'), ...
Authors:Li, C., Li, H., Zhou, S., Poulos, T.L., Gershon, P.D.
Deposit date:2008-10-01
Release date:2009-06-16
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (3.21 Å)
Cite:Polymerase Translocation with Respect to Single-Stranded Nucleic Acid: Looping or Wrapping of Primer around a Poly(A) Polymerase
Structure, 17, 2009
1AV6
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VACCINIA METHYLTRANSFERASE VP39 COMPLEXED WITH M7G CAPPED RNA HEXAMER AND S-ADENOSYLHOMOCYSTEINE
Descriptor:RNA (5'-R(*GP*AP*AP*AP*AP*A)-3'), Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase, 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Hodel, A.E., Gershon, P.D., Quiocho, F.A.
Deposit date:1997-09-26
Release date:1998-02-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for sequence-nonspecific recognition of 5'-capped mRNA by a cap-modifying enzyme.
Mol.Cell, 1, 1998
1B42
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VACCINIA METHYLTRANSFERASE VP39 COMPLEXED WITH M1ADE AND S-ADENOSYLHOMOCYSTEINE
Descriptor:VP39, S-ADENOSYL-L-HOMOCYSTEINE, 6-AMINO-1-METHYLPURINE
Authors:Hu, G., Hodel, A.E., Gershon, P.D., Quiocho, F.A.
Deposit date:1999-01-05
Release date:1999-07-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:mRNA cap recognition: dominant role of enhanced stacking interactions between methylated bases and protein aromatic side chains.
Proc.Natl.Acad.Sci.USA, 96, 1999
1BKY
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VACCINIA METHYLTRANSFERASE VP39 COMPLEXED WITH M1CYT AND S-ADENOSYLHOMOCYSTEINE
Descriptor:VP39, S-ADENOSYL-L-HOMOCYSTEINE, 1-METHYLCYTOSINE
Authors:Hu, G., Hodel, A.E., Gershon, P.D., Quiocho, F.A.
Deposit date:1998-07-13
Release date:1999-07-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:mRNA cap recognition: dominant role of enhanced stacking interactions between methylated bases and protein aromatic side chains.
Proc.Natl.Acad.Sci.USA, 96, 1999
1EAM
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VACCINIA METHYLTRANSFERASE VP39 MUTANT (EC: 2.7.7.19)
Descriptor:PROTEIN (VP39), S-ADENOSYL-L-HOMOCYSTEINE
Authors:Hu, G., Hodel, A.E., Gershon, P.D., Quiocho, F.A.
Deposit date:1999-01-26
Release date:1999-06-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:mRNA cap recognition: dominant role of enhanced stacking interactions between methylated bases and protein aromatic side chains.
Proc.Natl.Acad.Sci.USA, 96, 1999
1EQA
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VACCINIA METHYLTRANSFERASE VP39 MUTANT E233Q COMPLEXED WITH M7G AND S-ADENOSYLHOMOCYSTEINE
Descriptor:VP39, S-ADENOSYL-L-HOMOCYSTEINE, 7-METHYLGUANOSINE
Authors:Hu, G., Hodel, A.E., Gershon, P.D., Quiocho, F.A.
Deposit date:1999-01-05
Release date:1999-07-22
Last modified:2018-03-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:mRNA cap recognition: dominant role of enhanced stacking interactions between methylated bases and protein aromatic side chains.
Proc.Natl.Acad.Sci.USA, 96, 1999
1JSZ
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CRYSTAL STRUCTURE ANALYSIS OF N7,9-DIMETHYLGUANINE-VP39 COMPLEX
Descriptor:VP39, S-ADENOSYL-L-HOMOCYSTEINE, 7,9-DIMETHYLGUANINE
Authors:Hu, G., Oguro, A., Gershon, P.D., Quiocho, F.A.
Deposit date:2001-08-19
Release date:2002-07-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:The "cap-binding slot" of an mRNA cap-binding protein: quantitative effects of aromatic side chain choice in the double-stacking sandwich with cap.
Biochemistry, 41, 2002
1JTE
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CRYSTAL STRUCTURE ANALYSIS OF VP39 F180W MUTANT
Descriptor:VP39, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Hu, G., Oguro, A., Gershon, P.D., Quiocho, F.A.
Deposit date:2001-08-20
Release date:2002-07-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The "cap-binding slot" of an mRNA cap-binding protein: quantitative effects of aromatic side chain choice in the double-stacking sandwich with cap.
Biochemistry, 41, 2002
1JTF
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CRYSTAL STRUCTURE ANALYSIS OF VP39-F180W MUTANT AND M7GPPPG COMPLEX
Descriptor:VP39, S-ADENOSYL-L-HOMOCYSTEINE, 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE
Authors:Hu, G., Oguro, A., Gershon, P.D., Quiocho, F.A.
Deposit date:2001-08-20
Release date:2002-07-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The "cap-binding slot" of an mRNA cap-binding protein: quantitative effects of aromatic side chain choice in the double-stacking sandwich with cap.
Biochemistry, 41, 2002
2GA9
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CRYSTAL STRUCTURE OF THE HETERODIMERIC VACCINIA VIRUS POLYADENYLATE POLYMERASE WITH BOUND ATP-GAMMA-S
Descriptor:Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase, Poly(A) polymerase catalytic subunit, CALCIUM ION, ...
Authors:Moure, C.M., Bowman, B.R., Gershon, P.D., Quiocho, F.A.
Deposit date:2006-03-08
Release date:2006-05-16
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures of the vaccinia virus polyadenylate polymerase heterodimer: insights into ATP selectivity and processivity.
Mol.Cell, 22, 2006
2GAF
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CRYSTAL STRUCTURE OF THE VACCINIA POLYADENYLATE POLYMERASE HETERODIMER (APO FORM)
Descriptor:Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase, Poly(A) polymerase catalytic subunit
Authors:Moure, C.M., Bowman, B.R., Gershon, P.D., Quiocho, F.A.
Deposit date:2006-03-08
Release date:2006-05-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structures of the vaccinia virus polyadenylate polymerase heterodimer: insights into ATP selectivity and processivity.
Mol.Cell, 22, 2006
3MAG
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VACCINIA METHYLTRANSFERASE VP39 COMPLEXED WITH M3ADE AND S-ADENOSYLHOMOCYSTEINE
Descriptor:VP39, S-ADENOSYL-L-HOMOCYSTEINE, 6-AMINO-3-METHYLPURINE
Authors:Hu, G., Hodel, A.E., Gershon, P.D., Quiocho, F.A.
Deposit date:1998-07-12
Release date:1999-07-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:mRNA cap recognition: dominant role of enhanced stacking interactions between methylated bases and protein aromatic side chains.
Proc.Natl.Acad.Sci.USA, 96, 1999
3MCT
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VACCINIA METHYLTRANSFERASE VP39 COMPLEXED WITH M3CYT AND S-ADENOSYLHOMOCYSTEINE
Descriptor:VP39, S-ADENOSYL-L-HOMOCYSTEINE, 3-METHYLCYTOSINE
Authors:Hu, G., Gershon, P.D., Hodel, A.E., Quiocho, F.A.
Deposit date:1999-01-05
Release date:1999-07-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:mRNA cap recognition: dominant role of enhanced stacking interactions between methylated bases and protein aromatic side chains.
Proc.Natl.Acad.Sci.USA, 96, 1999
4DCG
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VACCINIA METHYLTRANSFERASE VP39 MUTANT D182A COMPLEXED WITH M7G AND S-ADENOSYLHOMOCYSTEINE
Descriptor:VP39, S-ADENOSYL-L-HOMOCYSTEINE, 7-METHYLGUANOSINE
Authors:Hu, G., Hodel, A.E., Gershon, P.D., Quiocho, F.A.
Deposit date:1998-07-13
Release date:1999-07-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:mRNA cap recognition: dominant role of enhanced stacking interactions between methylated bases and protein aromatic side chains.
Proc.Natl.Acad.Sci.USA, 96, 1999