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8KI5
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BU of 8ki5 by Molmil
PhmA, a type I diterpene synthase without NST/DTE motif
Descriptor: (2Z,6Z)-3,7,11-trimethyldodeca-2,6,10-trien-1-ol, PhmA
Authors:Zhang, B, Ge, H.M, Zhu, A, Zhang, Y.
Deposit date:2023-08-22
Release date:2023-10-04
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Biosynthesis of Platelet Activating Factor Antagonist Phomactins Revealing a New Class of Type I Diterpene Synthase
To Be Published
8KIH
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BU of 8kih by Molmil
PhmA, a type I diterpene synthase without NST/DTE motif
Descriptor: (2Z,6E,10E)-2-fluoro-3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraen-1-yl trihydrogen diphosphate, MAGNESIUM ION, diterpene synthase, ...
Authors:Zhang, B, Ge, H.M, Zhu, A, Zhang, Y.
Deposit date:2023-08-23
Release date:2023-10-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:Biosynthesis of Platelet Activating Factor Antagonist Phomactins Revealing a New Class of Type I Diterpene Synthase
To Be Published
7XSI
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BU of 7xsi by Molmil
SdnG, a Diels Alderase catalyzed the formation of norbornene skeleton in Sordarin biosynthetic pathway
Descriptor: Sordarin/hypoxysordarin biosynthesis cluster protein G
Authors:Zhang, B, Ge, H.M.
Deposit date:2022-05-14
Release date:2022-12-28
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Biosynthesis of Sordarin Revealing a Diels-Alderase for the Formation of the Norbornene Skeleton.
Angew.Chem.Int.Ed.Engl., 61, 2022
7YVV
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BU of 7yvv by Molmil
AcmP1, R-4-hydroxymandelate synthase
Descriptor: 4-hydroxyphenylpyruvate dioxygenase, CHLORIDE ION, FE (III) ION, ...
Authors:Zhang, B, Ge, H.M.
Deposit date:2022-08-19
Release date:2023-09-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Characterization of AcmP1 as the native R-4-hydroxymandelate synthase from biosynthetic pathway of Amycolamycins
To Be Published
7E36
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BU of 7e36 by Molmil
A [6+4]-cycloaddition adduct is the biosynthetic intermediate in streptoseomycin biosynthesis
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Alkanesulfonate monooxygenase SsuD/methylene tetrahydromethanopterin reductase-like flavin-dependent oxidoreductase (Luciferase family), ...
Authors:Zhang, B, Ge, H.M.
Deposit date:2021-02-08
Release date:2021-03-10
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:A [6+4]-cycloaddition adduct is the biosynthetic intermediate in streptoseomycin biosynthesis.
Nat Commun, 12, 2021
6J31
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BU of 6j31 by Molmil
Crystal Structure Analysis of the Glycotransferase of kitacinnamycin
Descriptor: (2E,2'E)-3,3'-(1,2-phenylene)di(prop-2-enoic acid), DBB-DSG-VAL-MEA-VAL-GLY-GLY-DVA-DLE, kcn28
Authors:Shi, J, Liu, C.L, Zhang, B, Guo, W.J, Zhu, J.P, Xu, X, Xu, Q, Jiao, R.H, Tan, R.X, Ge, H.M.
Deposit date:2019-01-03
Release date:2020-01-15
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.244 Å)
Cite:Genome mining and biosynthesis of kitacinnamycins as a STING activator.
Chem Sci, 10, 2019
6J32
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BU of 6j32 by Molmil
Crystal Structure Analysis of the Glycotransferase of kitacinnamycin
Descriptor: Kcn28
Authors:Shi, J, Liu, C.L, Zhang, B, Guo, W.J, Zhu, J.P, Xu, X, Xu, Q, Jiao, R.H, Tan, R.X, Ge, H.M.
Deposit date:2019-01-03
Release date:2020-01-15
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Genome mining and biosynthesis of kitacinnamycins as a STING activator.
Chem Sci, 10, 2019
6A52
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BU of 6a52 by Molmil
Oxidase ChaP-H1
Descriptor: FE (II) ION, dioxidase ChaP-H1
Authors:Zhang, B, Ge, H.M.
Deposit date:2018-06-21
Release date:2018-08-29
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Molecular Basis for the Final Oxidative Rearrangement Steps in Chartreusin Biosynthesis.
J. Am. Chem. Soc., 140, 2018
6A5F
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BU of 6a5f by Molmil
The structure of [4+2] and [6+4] cyclase in the biosynthetic pathway of nargenicin
Descriptor: NgnD
Authors:Zhang, B, Ge, H.M.
Deposit date:2018-06-23
Release date:2019-02-06
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Enzyme-catalysed [6+4] cycloadditions in the biosynthesis of natural products.
Nature, 568, 2019
6A4X
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BU of 6a4x by Molmil
Oxidase ChaP-H2
Descriptor: Bleomycin resistance protein, FE (II) ION
Authors:Zhang, B, Wang, Y.S, Ge, H.M.
Deposit date:2018-06-21
Release date:2018-08-29
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Molecular Basis for the Final Oxidative Rearrangement Steps in Chartreusin Biosynthesis.
J. Am. Chem. Soc., 140, 2018
6A4Z
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BU of 6a4z by Molmil
Oxidase ChaP
Descriptor: ChaP protein, FE (II) ION
Authors:Zhang, B, Ge, H.M.
Deposit date:2018-06-21
Release date:2018-08-29
Last modified:2018-09-19
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Molecular Basis for the Final Oxidative Rearrangement Steps in Chartreusin Biosynthesis.
J. Am. Chem. Soc., 140, 2018
6A5G
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BU of 6a5g by Molmil
The structure of [4+2] and [6+4] cyclase in the biosynthetic pathway of streptoseomycin
Descriptor: [4+2] and [4+6] cyclase StmD
Authors:Zhang, B, Ge, H.M.
Deposit date:2018-06-23
Release date:2019-02-06
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Enzyme-catalysed [6+4] cycloadditions in the biosynthesis of natural products.
Nature, 568, 2019
6A5H
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BU of 6a5h by Molmil
The structure of [4+2] and [6+4] cyclase in the biosynthetic pathway of unidentified natural product
Descriptor: 101015D
Authors:Zhang, B, Ge, H.M.
Deposit date:2018-06-23
Release date:2019-02-06
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.618 Å)
Cite:Enzyme-catalysed [6+4] cycloadditions in the biosynthesis of natural products.
Nature, 568, 2019
7FE5
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BU of 7fe5 by Molmil
AvmM Catalyzes Macrocyclization in Alchivemycin A Biosynthesis
Descriptor: AvmM, CACODYLATE ION, CHLORIDE ION
Authors:Zhang, B, Ge, H.M.
Deposit date:2021-07-19
Release date:2021-09-01
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:AvmM catalyses macrocyclization through dehydration/Michael-type addition in alchivemycin A biosynthesis.
Nat Commun, 13, 2022
7FE6
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BU of 7fe6 by Molmil
AvmM Catalyzes Macrocyclization in Alchivemycin A Biosynthesis
Descriptor: Alchivemycin A, AvmM, CHLORIDE ION
Authors:Zhang, B, Ge, H.M.
Deposit date:2021-07-19
Release date:2021-09-01
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:AvmM catalyses macrocyclization through dehydration/Michael-type addition in alchivemycin A biosynthesis.
Nat Commun, 13, 2022
7FE0
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BU of 7fe0 by Molmil
AvmM Catalyzes Macrocyclization in Alchivemycin A Biosynthesis
Descriptor: AvmM, CACODYLATE ION, CHLORIDE ION, ...
Authors:Zhang, B, Ge, H.M.
Deposit date:2021-07-19
Release date:2021-09-01
Last modified:2022-09-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:AvmM catalyses macrocyclization through dehydration/Michael-type addition in alchivemycin A biosynthesis.
Nat Commun, 13, 2022

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