Author results

1B9Y
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STRUCTURAL ANALYSIS OF PHOSDUCIN AND ITS PHOSPHORYLATION-REGULATED INTERACTION WITH TRANSDUCIN BETA-GAMMA
Descriptor:PROTEIN (TRANSDUCIN), PROTEIN (PHOSDUCIN), GADOLINIUM ATOM
Authors:Gaudet, R., Sigler, P.B.
Deposit date:1999-02-16
Release date:1999-02-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:A molecular mechanism for the phosphorylation-dependent regulation of heterotrimeric G proteins by phosducin.
Mol.Cell, 3, 1999
1B9X
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STRUCTURAL ANALYSIS OF PHOSDUCIN AND ITS PHOSPHORYLATION-REGULATED INTERACTION WITH TRANSDUCIN
Descriptor:PROTEIN (TRANSDUCIN), PROTEIN (PHOSDUCIN), GADOLINIUM ATOM
Authors:Gaudet, R., Sigler, P.B.
Deposit date:1999-02-16
Release date:1999-02-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:A molecular mechanism for the phosphorylation-dependent regulation of heterotrimeric G proteins by phosducin.
Mol.Cell, 3, 1999
1JJ7
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CRYSTAL STRUCTURE OF THE C-TERMINAL ATPASE DOMAIN OF HUMAN TAP1
Descriptor:PEPTIDE TRANSPORTER TAP1, MAGNESIUM ION, ADENOSINE-5'-DIPHOSPHATE
Authors:Gaudet, R., Wiley, D.C.
Deposit date:2001-07-03
Release date:2001-09-12
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of the ABC ATPase domain of human TAP1, the transporter associated with antigen processing.
EMBO J., 20, 2001
2TRC
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PHOSDUCIN/TRANSDUCIN BETA-GAMMA COMPLEX
Descriptor:TRANSDUCIN, PHOSDUCIN, GADOLINIUM ATOM
Authors:Gaudet, R., Bohm, A., Sigler, P.B.
Deposit date:1997-01-06
Release date:1997-06-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure at 2.4 angstroms resolution of the complex of transducin betagamma and its regulator, phosducin.
Cell(Cambridge,Mass.), 87, 1996
6D9W
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CRYSTAL STRUCTURE OF DEINOCOCCUS RADIODURANS MNTH, AN NRAMP-FAMILY TRANSITION METAL TRANSPORTER, IN THE INWARD-OPEN APO STATE
Descriptor:Divalent metal cation transporter MntH, Fab Heavy Chain, Fab Light Chain, ...
Authors:Gaudet, R., Bane, L.B., Weihofen, W.A., Singharoy, A., Zimanyi, C.M., Bozzi, A.T.
Deposit date:2018-04-30
Release date:2019-02-13
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (3.941 Å)
Cite:Structures in multiple conformations reveal distinct transition metal and proton pathways in an Nramp transporter.
Elife, 8, 2019
4K8O
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CRYSTAL STRUCTURE OF THE ATPASE DOMAIN OF TAP1 WITH ATP (D645N, D651A MUTANT)
Descriptor:Antigen peptide transporter 1, ADENOSINE-5'-TRIPHOSPHATE, NICKEL (II) ION, ...
Authors:Vakkasoglu, A.S., Grossmann, N., Hulpke, S., Abele, R., Tampe, R., Gaudet, R.
Deposit date:2013-04-18
Release date:2014-09-03
Last modified:2014-12-03
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Mechanistic determinants of the directionality and energetics of active export by a heterodimeric ABC transporter.
Nat Commun, 5, 2014
3JXI
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CRYSTAL STRUCTURE OF THE CHICKEN TRPV4 ANKYRIN REPEAT DOMAIN
Descriptor:Vanilloid receptor-related osmotically activated channel protein
Authors:Phelps, C.B., Wang, R.R., Gaudet, R.
Deposit date:2009-09-19
Release date:2009-12-22
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Mutations in TRPV4 cause Charcot-Marie-Tooth disease type 2C.
Nat.Genet., 42, 2010
3JXJ
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CRYSTAL STRUCTURE OF THE CHICKEN TRPV4 ANKYRIN REPEAT DOMAIN
Descriptor:Vanilloid receptor-related osmotically activated channel protein, PHOSPHATE ION
Authors:Phelps, C.B., Choo, S.S., Gaudet, R.
Deposit date:2009-09-19
Release date:2009-12-22
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Mutations in TRPV4 cause Charcot-Marie-Tooth disease type 2C.
Nat.Genet., 42, 2010
5UCG
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STRUCTURE OF THE PP2C PHOSPHATASE DOMAIN AND A FRAGMENT OF THE REGULATORY DOMAIN OF THE CELL FATE DETERMINANT SPOIIE FROM BACILLUS SUBTILIS
Descriptor:Stage II sporulation protein E
Authors:Bradshaw, N., Levdikov, V., Zimanyi, C., Gaudet, R., Wilkinson, A., Losick, R.
Deposit date:2016-12-22
Release date:2017-05-31
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (3.906 Å)
Cite:A widespread family of serine/threonine protein phosphatases shares a common regulatory switch with proteasomal proteases.
Elife, 6, 2017
1XD3
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CRYSTAL STRUCTURE OF UCHL3-UBVME COMPLEX
Descriptor:Ubiquitin Carboxyl-terminal esterase L3, UBC protein, MAGNESIUM ION, ...
Authors:Misaghi, S., Galardy, P.J., Meester, W.J.N., Ovaa, H., Ploegh, H.L., Gaudet, R.
Deposit date:2004-09-03
Release date:2004-11-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structure of the Ubiquitin Hydrolase UCH-L3 Complexed with a Suicide Substrate
J.Biol.Chem., 280, 2005
1IM3
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CRYSTAL STRUCTURE OF THE HUMAN CYTOMEGALOVIRUS PROTEIN US2 BOUND TO THE MHC CLASS I MOLECULE HLA-A2/TAX
Descriptor:HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, A-2 ALPHA CHAIN, beta-2-microglobulin, ...
Authors:Gewurz, B.E., Gaudet, R., Tortorella, D., Wang, E.W., Ploegh, H.L., Wiley, D.C.
Deposit date:2001-05-09
Release date:2001-06-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Antigen presentation subverted: Structure of the human cytomegalovirus protein US2 bound to the class I molecule HLA-A2.
Proc.Natl.Acad.Sci.USA, 98, 2001
2ETA
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CRYSTAL STRUCTURE OF THE ANKYRIN REPEAT DOMAIN OF THE TRPV2
Descriptor:Transient receptor potential cation channel subfamily V member 2
Authors:Jin, X., Gaudet, R.
Deposit date:2005-10-27
Release date:2006-06-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of the N-terminal Ankyrin Repeat Domain of the TRPV2 Ion Channel.
J.Biol.Chem., 281, 2006
2ETB
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CRYSTAL STRUCTURE OF THE ANKYRIN REPEAT DOMAIN OF TRPV2
Descriptor:Transient receptor potential cation channel subfamily V member 2, ACETIC ACID
Authors:Jin, X., Gaudet, R.
Deposit date:2005-10-27
Release date:2006-06-27
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structure of the N-terminal Ankyrin Repeat Domain of the TRPV2 Ion Channel.
J.Biol.Chem., 281, 2006
2ETC
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CRYSTAL STRUCTURE OF THE ANKYRIN REPEAT DOMAIN OF TRPV2
Descriptor:Transient receptor potential cation channel subfamily V member 2
Authors:Jin, X., Gaudet, R.
Deposit date:2005-10-27
Release date:2006-06-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure of the N-terminal Ankyrin Repeat Domain of the TRPV2 Ion Channel.
J.Biol.Chem., 281, 2006
2IXE
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CRYSTAL STRUCTURE OF THE ATPASE DOMAIN OF TAP1 WITH ATP (D645N MUTANT)
Descriptor:ANTIGEN PEPTIDE TRANSPORTER 1, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Procko, E., Ferrin-O'Connell, I., Ng, S.-L., Gaudet, R.
Deposit date:2006-07-07
Release date:2006-10-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Distinct Structural and Functional Properties of the ATPase Sites in an Asymmetric Abc Transporter.
Mol.Cell, 24, 2001
2IXF
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CRYSTAL STRUCTURE OF THE ATPASE DOMAIN OF TAP1 WITH ATP (D645Q, Q678H MUTANT)
Descriptor:ANTIGEN PEPTIDE TRANSPORTER 1, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Procko, E., Ferrin-O'Connell, I., Ng, S.-L., Gaudet, R.
Deposit date:2006-07-08
Release date:2006-10-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Distinct Structural and Functional Properties of the ATPase Sites in an Asymmetric Abc Transporter.
Mol.Cell, 24, 2001
2IXG
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CRYSTAL STRUCTURE OF THE ATPASE DOMAIN OF TAP1 WITH ATP (S621A, G622V, D645N MUTANT)
Descriptor:ANTIGEN PEPTIDE TRANSPORTER 1, ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL
Authors:Procko, E., Ferrin-O'Connell, I., Ng, S.-L., Gaudet, R.
Deposit date:2006-07-08
Release date:2006-10-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Distinct Structural and Functional Properties of the ATPase Sites in an Asymmetric Abc Transporter.
Mol.Cell, 24, 2001
2J7Q
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CRYSTAL STRUCTURE OF THE UBIQUITIN-SPECIFIC PROTEASE ENCODED BY MURINE CYTOMEGALOVIRUS TEGUMENT PROTEIN M48 IN COMPLEX WITH A UBQUITIN-BASED SUICIDE SUBSTRATE
Descriptor:MCMV TEGUMENT PROTEIN M48 ENCODED UBIQUITIN- SPECIFIC PROTEASE, M48USP, UBIQUITIN, ...
Authors:Schlieker, C., Weihofen, W.A., Frijns, E., Kattenhorn, L.M., Gaudet, R., Ploegh, H.L.
Deposit date:2006-10-16
Release date:2007-03-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of a Herpesvirus-Encoded Cysteine Protease Reveals a Unique Class of Deubiquitinating Enzymes
Mol.Cell, 25, 2007
2NYJ
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CRYSTAL STRUCTURE OF THE ANKYRIN REPEAT DOMAIN OF TRPV1
Descriptor:Transient receptor potential cation channel subfamily V member 1, ADENOSINE-5'-TRIPHOSPHATE
Authors:Jin, X., Gaudet, R.
Deposit date:2006-11-20
Release date:2007-07-03
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:The Ankyrin Repeats of TRPV1 Bind Multiple Ligands and Modulate Channel Sensitivity.
Neuron, 54, 2007
2PNN
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CRYSTAL STRUCTURE OF THE ANKYRIN REPEAT DOMAIN OF TRPV1
Descriptor:Transient receptor potential cation channel subfamily V member 1, ADENOSINE-5'-TRIPHOSPHATE
Authors:Jin, X., Gaudet, R.
Deposit date:2007-04-24
Release date:2007-07-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The Ankyrin Repeats of TRPV1 Bind Multiple Ligands and Modulate Channel Sensitivity.
Neuron, 54, 2007
2RFA
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CRYSTAL STRUCTURE OF THE MOUSE TRPV6 ANKYRIN REPEAT DOMAIN
Descriptor:Transient receptor potential cation channel subfamily V member 6
Authors:Phelps, C.B., Huang, R.J., Wang, R.R., Gaudet, R.
Deposit date:2007-09-28
Release date:2008-02-19
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural analyses of the ankyrin repeat domain of TRPV6 and related TRPV ion channels.
Biochemistry, 47, 2008
2WBX
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CRYSTAL STRUCTURE OF MOUSE CADHERIN-23 EC1
Descriptor:CADHERIN-23, CALCIUM ION
Authors:Sotomayor, M., Weihofen, W., Gaudet, R., Corey, D.P.
Deposit date:2009-03-05
Release date:2010-04-21
Last modified:2012-06-06
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural Determinants of Cadherin-23 Function in Hearing and Deafness.
Neuron, 66, 2010
2WCP
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CRYSTAL STRUCTURE OF MOUSE CADHERIN-23 EC1-2
Descriptor:CADHERIN-23, CALCIUM ION, SODIUM ION, ...
Authors:Sotomayor, M., Weihofen, W., Gaudet, R., Corey, D.P.
Deposit date:2009-03-13
Release date:2010-04-21
Last modified:2012-06-06
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Structural Determinants of Cadherin-23 Function in Hearing and Deafness.
Neuron, 66, 2010
2WD0
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CRYSTAL STRUCTURE OF NONSYNDROMIC DEAFNESS (DFNB12) ASSOCIATED MUTANT D124G OF MOUSE CADHERIN-23 EC1-2
Descriptor:CADHERIN-23, CALCIUM ION, SODIUM ION, ...
Authors:Sotomayor, M., Weihofen, W., Gaudet, R., Corey, D.P.
Deposit date:2009-03-18
Release date:2010-04-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.74 Å)
Cite:Structural Determinants of Cadherin-23 Function in Hearing and Deafness.
Neuron, 66, 2010
2WDT
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CRYSTAL STRUCTURE OF PLASMODIUM FALCIPARUM UCHL3 IN COMPLEX WITH THE SUICIDE INHIBITOR UBVME
Descriptor:UBIQUITIN CARBOXYL-TERMINAL HYDROLASE L3, UBIQUITIN, CHLORIDE ION
Authors:Weihofen, W.A., Artavanis-Tsakonas, K., Gaudet, R., Ploegh, H.L.
Deposit date:2009-03-26
Release date:2009-12-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Characterization and Structural Studies of the Plasmodium Falciparum Ubiquitin and Nedd8 Hydrolase Uchl3.
J.Biol.Chem., 285, 2010
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