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2CKB
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STRUCTURE OF THE 2C/KB/DEV8 COMPLEX
Descriptor:ALPHA, BETA T CELL RECEPTOR, MAJOR HISTOCOMPATIBILITY COMPLEX CLASS I MOLECULE K(B), ...
Authors:Garcia, K.C., Degano, M., Wilson, I.A.
Deposit date:1998-01-14
Release date:1998-04-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis of plasticity in T cell receptor recognition of a self peptide-MHC antigen.
Science, 279, 1998
1TCR
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MURINE T-CELL ANTIGEN RECEPTOR 2C CLONE
Descriptor:ALPHA, BETA T-CELL RECEPTOR (VB8.2DB2JB2.4CB2\;VA3JA58CA), N-ACETYL-D-GLUCOSAMINE, ...
Authors:Garcia, K.C., Degano, M., Stanfield, R.L., Wilson, I.A.
Deposit date:1996-09-12
Release date:1997-03-12
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:An alphabeta T cell receptor structure at 2.5 A and its orientation in the TCR-MHC complex.
Science, 274, 1996
2E7L
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STRUCTURE OF A HIGH-AFFINITY MUTANT OF THE 2C TCR IN COMPLEX WITH LD/QL9
Descriptor:Cytotoxic Tcell receptor, Beta-chain, H-2 class I histocompatibility antigen, ...
Authors:Garcia, K.C., Colf, L.A.
Deposit date:2007-01-11
Release date:2007-04-24
Last modified:2011-07-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:How a single T cell receptor recognizes both self and foreign MHC.
Cell(Cambridge,Mass.), 129, 2007
2NYK
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CRYSTAL STRUCTURE OF M157 FROM MOUSE CYTOMEGALOVIRUS
Descriptor:M157, N-ACETYL-D-GLUCOSAMINE, ALPHA-L-FUCOSE
Authors:Garcia, K.C.
Deposit date:2006-11-20
Release date:2007-05-29
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural elucidation of the m157 mouse cytomegalovirus ligand for Ly49 natural killer cell receptors.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2OI9
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STRUCTURE OF THE 2C/LD/QL9 ALLOGENEIC COMPLEX
Descriptor:Major Histocompatibility Complex protein, T cell receptor alpha chain, T cell receptor beta chain, ...
Authors:Garcia, K.C., Colf, L.A.
Deposit date:2007-01-10
Release date:2007-04-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:How a single T cell receptor recognizes both self and foreign MHC.
Cell(Cambridge,Mass.), 129, 2007
3BPL
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CRYSTAL STRUCTURE OF THE IL4-IL4R-COMMON GAMMA TERNARY COMPLEX
Descriptor:Interleukin-4, Interleukin-4 receptor alpha chain, Cytokine receptor common gamma chain, ...
Authors:Garcia, K.C.
Deposit date:2007-12-18
Release date:2008-02-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.93 Å)
Cite:Molecular and Structural Basis of Cytokine Receptor Pleiotropy in the Interleukin-4/13 System.
Cell(Cambridge,Mass.), 132, 2008
3BPN
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CRYSTAL STRUCTURE OF THE IL4-IL4R-IL13RA TERNARY COMPLEX
Descriptor:Interleukin-4, Interleukin-4 receptor alpha chain, Interleukin-13 receptor alpha-1 chain, ...
Authors:Garcia, K.C.
Deposit date:2007-12-18
Release date:2008-02-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.02 Å)
Cite:Molecular and Structural Basis of Cytokine Receptor Pleiotropy in the Interleukin-4/13 System.
Cell(Cambridge,Mass.), 132, 2008
3BPO
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CRYSTAL STRUCTURE OF THE IL13-IL4R-IL13RA TERNARY COMPLEX
Descriptor:Interleukin 13, Interleukin-4 receptor alpha chain, Interleukin-13 receptor alpha-1 chain, ...
Authors:Garcia, K.C.
Deposit date:2007-12-18
Release date:2008-02-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Molecular and Structural Basis of Cytokine Receptor Pleiotropy in the Interleukin-4/13 System.
Cell(Cambridge,Mass.), 132, 2008
5UK5
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COMPLEX OF NOTCH1(EGF8-12) BOUND TO JAGGED1(N-EGF3)
Descriptor:Neurogenic locus notch homolog protein 1, Protein jagged-1, CALCIUM ION, ...
Authors:Garcia, K.C., Luca, V.C.
Deposit date:2017-01-19
Release date:2017-03-08
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.506 Å)
Cite:Notch-Jagged complex structure implicates a catch bond in tuning ligand sensitivity.
Science, 355, 2017
1XFD
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STRUCTURE OF A HUMAN A-TYPE POTASSIUM CHANNEL ACCELERATING FACTOR DPPX, A MEMBER OF THE DIPEPTIDYL AMINOPEPTIDASE FAMILY
Descriptor:Dipeptidyl aminopeptidase-like protein 6, 2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Strop, P., Bankovich, A.J., Hansen, K.C., Garcia, K.C., Brunger, A.T.
Deposit date:2004-09-14
Release date:2004-10-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of a human A-type potassium channel interacting protein DPPX, a member of the dipeptidyl aminopeptidase family
J.Mol.Biol., 343, 2004
1G6R
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A FUNCTIONAL HOT SPOT FOR ANTIGEN RECOGNITION IN A SUPERAGONIST TCR/MHC COMPLEX
Descriptor:ALPHA T CELL RECEPTOR, BETA T CELL RECEPTOR, MAJOR HISTOCOMPATIBILITY COMPLEX CLASS I MOLECULE, ...
Authors:Degano, M., Garcia, K.C., Apostolopoulos, V., Rudolph, M.G., Teyton, L., Wilson, I.A.
Deposit date:2000-11-07
Release date:2000-11-15
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A functional hot spot for antigen recognition in a superagonist TCR/MHC complex.
Immunity, 12, 2000
1GNA
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DETERMINATION OF THE SOLUTION STRUCTURE OF THE PEPTIDE HORMONE GUANYLIN: OBSERVATION OF A NOVEL FORM OF TOPOLOGICAL STEREOISOMERISM
Descriptor:GUANYLIN PRECURSOR
Authors:Skelton, N.J., Garcia, K.C.
Deposit date:1994-06-30
Release date:1994-09-30
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Determination of the solution structure of the peptide hormone guanylin: observation of a novel form of topological stereoisomerism.
Biochemistry, 33, 1994
1GNB
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DETERMINATION OF THE SOLUTION STRUCTURE OF THE PEPTIDE HORMONE GUANYLIN: OBSERVATION OF A NOVEL FORM OF TOPOLOGICAL STEREOISOMERISM
Descriptor:GUANYLIN PRECURSOR
Authors:Skelton, N.J., Garcia, K.C.
Deposit date:1994-06-30
Release date:1994-09-30
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Determination of the solution structure of the peptide hormone guanylin: observation of a novel form of topological stereoisomerism.
Biochemistry, 33, 1994
1I1R
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CRYSTAL STRUCTURE OF A CYTOKINE/RECEPTOR COMPLEX
Descriptor:INTERLEUKIN-6 RECEPTOR BETA CHAIN, VIRAL IL-6
Authors:Chow, D., He, X., Snow, A.L., Rose-John, S., Garcia, K.C.
Deposit date:2001-02-02
Release date:2001-03-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of an extracellular gp130 cytokine receptor signaling complex.
Science, 291, 2001
1JDN
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CRYSTAL STRUCTURE OF HORMONE RECEPTOR
Descriptor:ATRIAL NATRIURETIC PEPTIDE CLEARANCE RECEPTOR, 2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE, BETA-D-MANNOSE, ...
Authors:He, X.-L., Chow, D.-C., Martick, M.M., Garcia, K.C.
Deposit date:2001-06-14
Release date:2001-09-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Allosteric activation of a spring-loaded natriuretic peptide receptor dimer by hormone.
Science, 293, 2001
1JDP
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CRYSTAL STRUCTURE OF HORMONE/RECEPTOR COMPLEX
Descriptor:ATRIAL NATRIURETIC PEPTIDE CLEARANCE RECEPTOR, C-TYPE NATRIURETIC PEPTIDE, 2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE, ...
Authors:He, X.-L., Chow, D.-C., Martick, M.M., Garcia, K.C.
Deposit date:2001-06-14
Release date:2001-09-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Allosteric activation of a spring-loaded natriuretic peptide receptor dimer by hormone.
Science, 293, 2001
1K2D
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CRYSTAL STRUCTURE OF THE AUTOIMMUNE MHC CLASS II I-AU COMPLEXED WITH MYELIN BASIC PROTEIN 1-11 AT 2.2A
Descriptor:H-2 class II histocompatibility antigen, A-U alpha chain, A-U beta chain, ...
Authors:He, X.L., Radu, C., Ward, E.S., Garcia, K.C.
Deposit date:2001-09-26
Release date:2003-03-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural snapshot of aberrant antigen presentation linked to autoimmunity: the immunodominant epitope of MBP complexed with I-Au
IMMUNITY, 17, 2002
1K8D
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CRYSTAL STRUCTURE OF THE NON-CLASSICAL MHC CLASS IB QA-2 COMPLEXED WITH A SELF PEPTIDE
Descriptor:QA-2 antigen, BETA-2-MICROGLOBULIN, 60S RIBOSOMAL PROTEIN
Authors:He, X., Tabaczewski, P., Ho, J., Stroynowski, I., Garcia, K.C.
Deposit date:2001-10-23
Release date:2001-12-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Promiscuous antigen presentation by the nonclassical MHC Ib Qa-2 is enabled by a shallow, hydrophobic groove and self-stabilized peptide conformation.
Structure, 9, 2001
1KZQ
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CRYSTAL STRUCTURE OF A PARASITE PROTEIN
Descriptor:Major Surface Antigen P30
Authors:He, X., Grigg, M.E., Boothroyd, J.C., Garcia, K.C.
Deposit date:2002-02-07
Release date:2002-07-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure of the immunodominant surface antigen from the Toxoplasma gondii SRS superfamily.
Nat.Struct.Biol., 9, 2002
1LEG
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CRYSTAL STRUCTURE OF H-2KB BOUND TO THE DEV8 PEPTIDE
Descriptor:H-2 CLASS I HISTOCOMPATIBILITY ANTIGEN, K-B ALPHA CHAIN, BETA-2-MICROGLOBULIN, ...
Authors:Luz, J.G., Huang, M., Garcia, K.C., Rudolph, M.G., Apostolopoulos, V., Teyton, L., Wilson, I.A.
Deposit date:2002-04-09
Release date:2002-06-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural comparison of allogeneic and syngeneic T cell receptor-peptide-major histocompatibility complex complexes: a buried alloreactive mutation subtly alters peptide presentation substantially increasing V(beta) Interactions.
J.Exp.Med., 195, 2002
1LEK
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CRYSTAL STRUCTURE OF H-2KBM3 BOUND TO DEV8
Descriptor:H-2 CLASS I HISTOCOMPATIBILITY ANTIGEN, K-B ALPHA CHAIN, Beta-2-microglobulin, ...
Authors:Luz, J.G., Huang, M., Garcia, K.C., Rudolph, M.G., Apostolopoulos, V., Teyton, L., Wilson, I.A.
Deposit date:2002-04-09
Release date:2002-06-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural comparison of allogeneic and syngeneic T cell receptor-peptide-major histocompatibility complex complexes: a buried alloreactive mutation subtly alters peptide presentation substantially increasing V(beta) Interactions.
J.Exp.Med., 195, 2002
1MWA
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2C/H-2KBM3/DEV8 ALLOGENEIC COMPLEX
Descriptor:2C T CELL RECEPTOR ALPHA CHAIN, 2C T CELL RECEPTOR BETA CHAIN, H-2KBM3 MHC CLASS I MOLECULE HEAVY CHAIN, ...
Authors:Luz, J.G., Huang, M.D., Garcia, K.C., Rudolph, M.G., Teyton, L., Wilson, I.A.
Deposit date:2002-09-27
Release date:2002-11-27
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural comparison of allogeneic and syngeneic T cell receptor-peptide-major histocompatibility complex complexes: a buried alloreactive mutation subtly alters peptide presentation substantially increasing V(beta) Interactions.
J.EXP.MED., 195, 2002
1OZN
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1.5A CRYSTAL STRUCTURE OF THE NOGO RECEPTOR LIGAND BINDING DOMAIN REVEALS A CONVERGENT RECOGNITION SCAFFOLD MEDIATING INHIBITION OF MYELINATION
Descriptor:Reticulon 4 receptor, 2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE, ALPHA-D-MANNOSE, ...
Authors:He, X., Bazan, J.F., Park, J.B., McDermott, G., He, Z., Garcia, K.C.
Deposit date:2003-04-09
Release date:2003-05-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:Structure of the Nogo Receptor Ectodomain. A Recognition module implicated in Myelin Inhibition.
Neuron, 38, 2003
1P9M
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CRYSTAL STRUCTURE OF THE HEXAMERIC HUMAN IL-6/IL-6 ALPHA RECEPTOR/GP130 COMPLEX
Descriptor:Interleukin-6 receptor beta chain, Interleukin-6, Interleukin-6 receptor alpha chain
Authors:Boulanger, M.J., Chow, D.C., Brevnova, E.E., Garcia, K.C.
Deposit date:2003-05-12
Release date:2003-07-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.65 Å)
Cite:Hexameric Structure and Assembly of the Interleukin-6/IL-6 alpha-Receptor/gp130 Complex
Science, 300, 2003
1PVH
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CRYSTAL STRUCTURE OF LEUKEMIA INHIBITORY FACTOR IN COMPLEX WITH GP130
Descriptor:Interleukin-6 receptor beta chain, Leukemia inhibitory factor, IODIDE ION
Authors:Boulanger, M.J., Bankovich, A.J., Kortemme, T., Baker, D., Garcia, K.C.
Deposit date:2003-06-27
Release date:2003-10-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Convergent mechanisms for recognition of divergent cytokines by the shared signaling receptor gp130.
Mol.Cell, 12, 2003