Author results

6J5W
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LIGAND-TRIGGERED ALLOSTERIC ADP RELEASE PRIMES A PLANT NLR COMPLEX
Descriptor:RKS1, Disease resistance RPP13-like protein 4, ADENOSINE-5'-DIPHOSPHATE
Authors:Wang, J.Z., Wang, J., Hu, M.J., Wang, H.W., Zhou, J.M., Chai, J.J.
Deposit date:2019-01-12
Release date:2019-04-03
Last modified:2019-04-17
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Ligand-triggered allosteric ADP release primes a plant NLR complex.
Science, 364, 2019
6J5V
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LIGAND-TRIGGERED ALLOSTERIC ADP RELEASE PRIMES A PLANT NLR COMPLEX
Descriptor:Disease resistance RPP13-like protein 4, Probable serine/threonine-protein kinase PBL2, Protein kinase superfamily protein, ...
Authors:Wang, J.Z., Wang, J., Hu, M.J., Wang, H.W., Zhou, J.M., Chai, J.J.
Deposit date:2019-01-12
Release date:2019-04-03
Last modified:2019-04-17
Method:ELECTRON MICROSCOPY (4.25 Å)
Cite:Ligand-triggered allosteric ADP release primes a plant NLR complex.
Science, 364, 2019
6J5U
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LIGAND-TRIGGERED ALLOSTERIC ADP RELEASE PRIMES A PLANT NLR COMPLEX
Descriptor:Disease resistance RPP13-like protein 4, Probable serine/threonine-protein kinase PBL2, Protein kinase superfamily protein, ...
Authors:Wang, J.Z., Wang, J., Meijuan, H., Wang, H.W., Zhou, J.M., Chai, J.J.
Deposit date:2019-01-12
Release date:2019-04-03
Last modified:2019-04-17
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Ligand-triggered allosteric ADP release primes a plant NLR complex.
Science, 364, 2019
6J0N
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CRYO-EM STRUCTURE OF AN EXTRACELLULAR CONTRACTILE INJECTION SYSTEM, BASEPLATE IN EXTENDED STATE, REFINED IN C6 SYMMETRY
Descriptor:Pvc9, Pvc11, Pvc12, ...
Authors:Jiang, F., Li, N., Wang, X., Cheng, J., Huang, Y., Yang, Y., Yang, J., Cai, B., Wang, Y., Jin, Q., Gao, N.
Deposit date:2018-12-25
Release date:2019-04-10
Last modified:2019-04-17
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Cryo-EM Structure and Assembly of an Extracellular Contractile Injection System.
Cell, 177, 2019
6J0M
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CRYO-EM STRUCTURE OF AN EXTRACELLULAR CONTRACTILE INJECTION SYSTEM, PVC BASEPLATE IN EXTENDED STATE (RECONSTRUCTED WITH C3 SYMMETRY)
Descriptor:Pvc8
Authors:Jiang, F., Li, N., Wang, X., Cheng, J., Huang, Y., Yang, Y., Yang, J., Cai, B., Wang, Y., Jin, Q., Gao, N.
Deposit date:2018-12-24
Release date:2019-04-10
Last modified:2019-04-17
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Cryo-EM Structure and Assembly of an Extracellular Contractile Injection System.
Cell, 177, 2019
6J0F
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CRYO-EM STRUCTURE OF AN EXTRACELLULAR CONTRACTILE INJECTION SYSTEM, PVC SHEATH/TUBE TERMINATOR IN EXTENDED STATE
Descriptor:Pvc16, Pvc1
Authors:Jiang, F., Li, N., Wang, X., Cheng, J., Huang, Y., Yang, Y., Yang, J., Cai, B., Wang, Y., Jin, Q., Gao, N.
Deposit date:2018-12-24
Release date:2019-04-10
Last modified:2019-04-17
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Cryo-EM Structure and Assembly of an Extracellular Contractile Injection System.
Cell, 177, 2019
6J0C
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CRYO-EM STRUCTURE OF AN EXTRACELLULAR CONTRACTILE INJECTION SYSTEM, PVC SHEATH COMPLEX IN CONTRACTED STATE
Descriptor:Pvc2
Authors:Jiang, F., Li, N., Wang, X., Cheng, J., Huang, Y., Yang, Y., Yang, J., Cai, B., Wang, Y., Jin, Q., Gao, N.
Deposit date:2018-12-23
Release date:2019-04-10
Last modified:2019-04-17
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Cryo-EM Structure and Assembly of an Extracellular Contractile Injection System.
Cell, 177, 2019
6J0B
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CRYO-EM STRUCTURE OF AN EXTRACELLULAR CONTRACTILE INJECTION SYSTEM, PVC SHEATH-TUBE COMPLEX IN EXTENDED STATE
Descriptor:Pvc2, Pvc1
Authors:Jiang, F., Li, N., Wang, X., Cheng, J., Huang, Y., Yang, Y., Yang, J., Cai, B., Wang, Y., Jin, Q., Gao, N.
Deposit date:2018-12-23
Release date:2019-04-10
Last modified:2019-04-17
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Cryo-EM Structure and Assembly of an Extracellular Contractile Injection System.
Cell, 177, 2019
6IV6
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CRYO-EM STRUCTURE OF ACRVA5-ACETYLATED MBCAS12A IN COMPLEX WITH CRRNA
Descriptor:nuclease, RNA (59-MER)
Authors:Dong, L., Li, N., Guan, X., Zhu, Y., Gao, N., Huang, Z.
Deposit date:2018-12-02
Release date:2019-04-10
Last modified:2019-04-17
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:An anti-CRISPR protein disables type V Cas12a by acetylation.
Nat. Struct. Mol. Biol., 26, 2019
6IUF
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CRYSTAL STRUCTURE OF ANTI-CRISPR PROTEIN ACRVA5
Descriptor:protein-a, ACETYL COENZYME *A, GLYCEROL
Authors:Dong, L., Guan, X., Zhu, Y., Huang, Z.
Deposit date:2018-11-28
Release date:2019-04-10
Last modified:2019-04-17
Method:X-RAY DIFFRACTION (2.052 Å)
Cite:An anti-CRISPR protein disables type V Cas12a by acetylation.
Nat. Struct. Mol. Biol., 26, 2019
6IRO
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THE CROSSLINKED COMPLEX OF ISWI-NUCLEOSOME IN THE ADP-BOUND STATE
Descriptor:ISWI chromatin-remodeling complex ATPase ISW1, Histone H3, Histone H4, ...
Authors:Yan, L.J., Wu, H., Li, X.M., Gao, N., Chen, Z.C.
Deposit date:2018-11-13
Release date:2019-04-03
Last modified:2019-04-17
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structures of the ISWI-nucleosome complex reveal a conserved mechanism of chromatin remodeling.
Nat. Struct. Mol. Biol., 26, 2019
6IRN
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THE COMPLEX OF ISWI-NUCLEOSOME IN THE ADP.BEF-BOUND STATE
Descriptor:Histone H3, Histone H4, Histone H2A, ...
Authors:Yan, L.J., Wu, H., Li, X.M., Gao, N., Chen, Z.C.
Deposit date:2018-11-13
Release date:2019-04-03
Last modified:2019-04-17
Method:ELECTRON MICROSCOPY (3.87 Å)
Cite:Structures of the ISWI-nucleosome complex reveal a conserved mechanism of chromatin remodeling.
Nat. Struct. Mol. Biol., 26, 2019
6IRM
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THE CROSSLINKED COMPLEX OF ISWI-NUCLEOSOME IN THE ADP.BEF-BOUND STATE
Descriptor:Histone H3, Histone H4, Histone H2A, ...
Authors:Yan, L.J., Wu, H., Li, X.M., Gao, N., Chen, Z.C.
Deposit date:2018-11-13
Release date:2019-04-10
Last modified:2019-04-17
Method:ELECTRON MICROSCOPY (3.37 Å)
Cite:Structures of the ISWI-nucleosome complex reveal a conserved mechanism of chromatin remodeling.
Nat. Struct. Mol. Biol., 26, 2019
6EW8
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CRYSTAL STRUCTURE OF THE BCL6 BTB DOMAIN IN COMPLEX WITH ANILINOPYRIMIDINE LIGAND
Descriptor:B-cell lymphoma 6 protein, CHLORIDE ION, anilinopyrimidine ligand
Authors:Robb, G., Ferguson, A., Hargreaves, D.
Deposit date:2017-11-03
Release date:2018-10-24
Last modified:2018-11-28
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Development of a Novel B-Cell Lymphoma 6 (BCL6) PROTAC To Provide Insight into Small Molecule Targeting of BCL6.
ACS Chem. Biol., 13, 2018
6EW7
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CRYSTAL STRUCTURE OF THE BCL6 BTB DOMAIN IN COMPLEX WITH ANILINOPYRIMIDINE LIGAND
Descriptor:B-cell lymphoma 6 protein, CHLORIDE ION, 2-chloranyl-4-[[5-chloranyl-4-[(4-fluorophenyl)amino]pyrimidin-2-yl]amino]benzoic acid
Authors:Robb, G., Ferguson, A., Hargreaves, D.
Deposit date:2017-11-03
Release date:2018-10-24
Last modified:2018-11-28
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Development of a Novel B-Cell Lymphoma 6 (BCL6) PROTAC To Provide Insight into Small Molecule Targeting of BCL6.
ACS Chem. Biol., 13, 2018
6EW6
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CRYSTAL STRUCTURE OF THE BCL6 BTB DOMAIN IN COMPLEX WITH ANILINOPYRIMIDINE LIGAND
Descriptor:B-cell lymphoma 6 protein, ~{N}2-(2-chlorophenyl)-1,3,5-triazine-2,4-diamine
Authors:Robb, G., Ferguson, A., Hargreaves, D.
Deposit date:2017-11-03
Release date:2018-10-24
Last modified:2018-11-28
Method:X-RAY DIFFRACTION (1.39 Å)
Cite:Development of a Novel B-Cell Lymphoma 6 (BCL6) PROTAC To Provide Insight into Small Molecule Targeting of BCL6.
ACS Chem. Biol., 13, 2018
6B3E
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CRYSTAL STRUCTURE OF HUMAN CDK12/CYCLINK IN COMPLEX WITH AN INHIBITOR
Descriptor:Cyclin-dependent kinase 12, Cyclin-K, MAGNESIUM ION, ...
Authors:Ferguson, A.D.
Deposit date:2017-09-21
Release date:2017-12-27
Last modified:2018-02-21
Method:X-RAY DIFFRACTION (3.06 Å)
Cite:Structure-Based Design of Selective Noncovalent CDK12 Inhibitors.
ChemMedChem, 13, 2018
5ZRV
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STRUCTURE OF HUMAN MITOCHONDRIAL TRIFUNCTIONAL PROTEIN, OCTAMER
Descriptor:Trifunctional enzyme subunit alpha, mitochondrial, Trifunctional enzyme subunit beta
Authors:Liang, K., Li, N., Dai, J., Wang, X., Liu, P., Chen, X., Wang, C., Gao, N., Xiao, J.
Deposit date:2018-04-25
Release date:2018-06-20
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (7.7 Å)
Cite:Cryo-EM structure of human mitochondrial trifunctional protein
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5ZR1
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SACCHAROMYCES CEREVISIAE ORIGIN RECOGNITION COMPLEX BOUND TO A 72-BP ORIGIN DNA CONTAINING ACS AND B1 ELEMENT
Descriptor:Origin recognition complex subunit 1, Origin recognition complex subunit 2, Origin recognition complex subunit 3, ...
Authors:Li, N., Lam, W.H., Zhai, Y., Cheng, J., Cheng, E., Zhao, Y., Gao, N., Tye, B.K.
Deposit date:2018-04-21
Release date:2018-07-11
Last modified:2018-07-25
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structure of the origin recognition complex bound to DNA replication origin.
Nature, 559, 2018
5ZQZ
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STRUCTURE OF HUMAN MITOCHONDRIAL TRIFUNCTIONAL PROTEIN, TETRAMER
Descriptor:Trifunctional enzyme subunit alpha, mitochondrial, Trifunctional enzyme subunit beta
Authors:Liang, K., Li, N., Dai, J., Wang, X., Liu, P., Chen, X., Wang, C., Gao, N., Xiao, J.
Deposit date:2018-04-20
Release date:2018-06-20
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Cryo-EM structure of human mitochondrial trifunctional protein
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5YE5
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STRUCTURE OF ENDO-LYSOSOMAL TRPML1 CHANNEL INSERTING INTO NANODISC
Descriptor:mammalian endo-lysosomal TRPML1 channel, N-ACETYL-D-GLUCOSAMINE
Authors:Yang, M., Gao, N.
Deposit date:2017-09-15
Release date:2017-11-15
Last modified:2017-11-22
Method:ELECTRON MICROSCOPY (5.8 Å)
Cite:Cryo-EM structures of the mammalian endo-lysosomal TRPML1 channel elucidate the combined regulation mechanism
Protein Cell, 8, 2017
5YE2
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MAMMALIAN ENDO-LYSOSOMAL TRPML1 CHANNEL INSERTING INTO AMPHIPOL
Descriptor:mammalian endo-lysosomal TRPML1 channel
Authors:Yang, M., Gao, N.
Deposit date:2017-09-15
Release date:2017-12-27
Method:ELECTRON MICROSCOPY (5.8 Å)
Cite:Cryo-EM structures of the mammalian endo-lysosomal TRPML1 channel elucidate the combined regulation mechanism
Protein Cell, 8, 2017
5YE1
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STRUCTURE OF ENDO-LYSOSOMAL TRPML1 CHANNEL INSERTING INTO AMPHIPOL: STATE 2
Descriptor:Mucolipin-1
Authors:Yang, M., Gao, N.
Deposit date:2017-09-15
Release date:2017-12-27
Method:ELECTRON MICROSCOPY (5.8 Å)
Cite:Cryo-EM structures of the mammalian endo-lysosomal TRPML1 channel elucidate the combined regulation mechanism
Protein Cell, 8, 2017
5YDZ
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STRUCTURE OF ENDO-LYSOSOMAL TRPML1 CHANNEL INSERTING INTO AMPHIPOL: STATE 1
Descriptor:mammalian endo-lysosomal TRPML1 channel
Authors:Yang, M., Gao, N.
Deposit date:2017-09-15
Release date:2017-12-27
Method:ELECTRON MICROSCOPY (5.8 Å)
Cite:Cryo-EM structures of the mammalian endo-lysosomal TRPML1 channel elucidate the combined regulation mechanism
Protein Cell, 8, 2017
5Y4O
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CRYO-EM STRUCTURE OF MSCS CHANNEL, YNAI
Descriptor:Low conductance mechanosensitive channel YnaI
Authors:Zhang, Y., Yu, J.
Deposit date:2017-08-04
Release date:2019-03-20
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:A binding-block ion selective mechanism revealed by a Na/K selective channel.
Protein Cell, 9, 2018