Author results

6NDJ
  • Download 6ndj
  • View 6ndj
Molmil generated image of 6ndj
CRYSTAL STRUCTURE OF HUMAN NLRP6 PYD DOMAIN WITH MBP FUSION
Descriptor:Maltose/maltodextrin-binding periplasmic protein, NACHT, LRR and PYD domains-containing protein 6 chimera
Authors:Shen, C., Fu, T.M., Wu, H.
Deposit date:2018-12-13
Release date:2019-01-23
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Molecular mechanism for NLRP6 inflammasome assembly and activation.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
6NCV
  • Download 6ncv
  • View 6ncv
Molmil generated image of 6ncv
CRYO-EM STRUCTURE OF NLRP6 PYD FILAMENT
Descriptor:NACHT, LRR and PYD domains-containing protein 6
Authors:Shen, C., Fu, T.M., Wu, H.
Deposit date:2018-12-12
Release date:2019-01-23
Last modified:2019-02-20
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Molecular mechanism for NLRP6 inflammasome assembly and activation.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
6N1H
  • Download 6n1h
  • View 6n1h
Molmil generated image of 6n1h
CRYO-EM STRUCTURE OF ASC-CARD FILAMENT
Descriptor:Apoptosis-associated speck-like protein containing a CARD
Authors:Li, Y., Fu, T., Wu, H.
Deposit date:2018-11-08
Release date:2018-12-05
Method:ELECTRON MICROSCOPY (3.17 Å)
Cite:Cryo-EM structures of ASC and NLRC4 CARD filaments reveal a unified mechanism of nucleation and activation of caspase-1.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6N1I
  • Download 6n1i
  • View 6n1i
Molmil generated image of 6n1i
CRYO-EM STRUCTURE OF NLRC4-CARD FILAMENT
Descriptor:NLR family CARD domain-containing protein 4
Authors:Li, Y., Fu, T., Wu, H.
Deposit date:2018-11-08
Release date:2018-12-05
Method:ELECTRON MICROSCOPY (3.58 Å)
Cite:Cryo-EM structures of ASC and NLRC4 CARD filaments reveal a unified mechanism of nucleation and activation of caspase-1.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6MIX
  • Download 6mix
  • View 6mix
Molmil generated image of 6mix
HUMAN TRPM2 ION CHANNEL IN APO STATE
Descriptor:Transient receptor potential cation channel subfamily M member 2
Authors:Wang, L., Fu, T.M., Xia, S., Wu, H.
Deposit date:2018-09-20
Release date:2018-12-12
Last modified:2019-01-02
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structures and gating mechanism of human TRPM2.
Science, 362, 2018
6MIZ
  • Download 6miz
  • View 6miz
Molmil generated image of 6miz
HUMAN TRPM2 ION CHANNEL IN AN ADPR-BOUND STATE
Descriptor:Transient receptor potential cation channel subfamily M member 2
Authors:Wang, L., Fu, T.M., Xia, S., Wu, H.
Deposit date:2018-09-20
Release date:2018-12-12
Last modified:2019-01-02
Method:ELECTRON MICROSCOPY (6.1 Å)
Cite:Structures and gating mechanism of human TRPM2.
Science, 362, 2018
6MJ2
  • Download 6mj2
  • View 6mj2
Molmil generated image of 6mj2
HUMAN TRPM2 ION CHANNEL IN A CALCIUM- AND ADPR-BOUND STATE
Descriptor:Transient receptor potential cation channel subfamily M member 2, CALCIUM ION
Authors:Wang, L., Fu, T.M., Xia, S., Wu, H.
Deposit date:2018-09-20
Release date:2018-12-12
Last modified:2019-01-02
Method:ELECTRON MICROSCOPY (6.36 Å)
Cite:Structures and gating mechanism of human TRPM2.
Science, 362, 2018
5L08
  • Download 5l08
  • View 5l08
Molmil generated image of 5l08
CRYO-EM STRUCTURE OF CASP-8 TDED FILAMENT
Descriptor:Caspase-8
Authors:Fu, T.M., Li, Y., Lu, A., Wu, H.
Deposit date:2016-07-26
Release date:2016-11-02
Last modified:2016-11-30
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Cryo-EM Structure of Caspase-8 Tandem DED Filament Reveals Assembly and Regulation Mechanisms of the Death-Inducing Signaling Complex.
Mol.Cell, 64, 2016
5JQE
  • Download 5jqe
  • View 5jqe
Molmil generated image of 5jqe
CRYSTAL STRUCTURE OF CASPASE8 TDED
Descriptor:Sugar ABC transporter substrate-binding protein,Caspase-8 chimera
Authors:Fu, T., Li, Y., Lu, A., Wu, H.
Deposit date:2016-05-04
Release date:2016-10-26
Last modified:2018-02-21
Method:X-RAY DIFFRACTION (3.157 Å)
Cite:Cryo-EM Structure of Caspase-8 Tandem DED Filament Reveals Assembly and Regulation Mechanisms of the Death-Inducing Signaling Complex.
Mol. Cell, 64, 2016
2NA6
  • Download 2na6
  • View 2na6
Molmil generated image of 2na6
TRANSMEMBRANE DOMAIN OF MOUSE FAS/CD95 DEATH RECEPTOR
Descriptor:Tumor necrosis factor receptor superfamily member 6
Authors:Fu, Q., Chou, J.J., Wu, H., Fu, T., Membrane Protein Structures by Solution NMR (MPSbyNMR)
Deposit date:2015-12-21
Release date:2016-01-27
Last modified:2016-03-02
Method:SOLUTION NMR
Cite:Structural Basis and Functional Role of Intramembrane Trimerization of the Fas/CD95 Death Receptor.
Mol.Cell, 61, 2016
2NA7
  • Download 2na7
  • View 2na7
Molmil generated image of 2na7
TRANSMEMBRANE DOMAIN OF HUMAN FAS/CD95 DEATH RECEPTOR
Descriptor:Tumor necrosis factor receptor superfamily member 6
Authors:Fu, Q., Chou, J.J., Membrane Protein Structures by Solution NMR (MPSbyNMR)
Deposit date:2015-12-21
Release date:2016-01-27
Last modified:2016-03-02
Method:SOLUTION NMR
Cite:Structural Basis and Functional Role of Intramembrane Trimerization of the Fas/CD95 Death Receptor.
Mol.Cell, 61, 2016
5FNA
  • Download 5fna
  • View 5fna
Molmil generated image of 5fna
CRYO-EM RECONSTRUCTION OF CASPASE-1 CARD
Descriptor:CASPASE-1
Authors:Li, Y., Lu, A., Schmidt, F.I., Yin, Q., Chen, S., Fu, T.M., Tong, A.B., Ploegh, H.L., Mao, Y., Wu, H.
Deposit date:2015-11-11
Release date:2016-03-30
Last modified:2017-08-30
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Molecular Basis of Caspase-1 Polymerization and its Inhibition by a Novel Capping Mechanism
Nat.Struct.Mol.Biol., 23, 2016
3JBX
  • Download 3jbx
  • View 3jbx
Molmil generated image of 3jbx
CRYO-ELECTRON MICROSCOPY STRUCTURE OF RAG SIGNAL END COMPLEX (C2 SYMMETRY)
Descriptor:V(D)J recombination-activating protein 1, V(D)J recombination-activating protein 2, 5'-D(*CP*AP*CP*AP*GP*TP*GP*CP*TP*AP*CP*AP*GP*AP*C)-3', ...
Authors:Ru, H., Chambers, M.G., Fu, T.-M., Tong, A.B., Liao, M., Wu, H.
Deposit date:2015-10-22
Release date:2015-12-09
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Molecular Mechanism of V(D)J Recombination from Synaptic RAG1-RAG2 Complex Structures.
Cell(Cambridge,Mass.), 163, 2015
3JBY
  • Download 3jby
  • View 3jby
Molmil generated image of 3jby
CRYO-ELECTRON MICROSCOPY STRUCTURE OF RAG PAIRED COMPLEX (C2 SYMMETRY)
Descriptor:V(D)J recombination-activating protein 1, V(D)J recombination-activating protein 2, 5'-D(P*CP*AP*CP*AP*GP*TP*GP*CP*TP*AP*CP*AP*GP*AP*C)-3', ...
Authors:Ru, H., Chambers, M.G., Fu, T.-M., Tong, A.B., Liao, M., Wu, H.
Deposit date:2015-10-22
Release date:2015-12-09
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Molecular Mechanism of V(D)J Recombination from Synaptic RAG1-RAG2 Complex Structures.
Cell(Cambridge,Mass.), 163, 2015
3JBW
  • Download 3jbw
  • View 3jbw
Molmil generated image of 3jbw
CRYO-ELECTRON MICROSCOPY STRUCTURE OF RAG PAIRED COMPLEX (WITH NBD, NO SYMMETRY)
Descriptor:V(D)J recombination-activating protein 1, V(D)J recombination-activating protein 2, 12-RSS signal end forward strand, ...
Authors:Ru, H., Chambers, M.G., Fu, T.-M., Tong, A.B., Liao, M., Wu, H.
Deposit date:2015-10-21
Release date:2015-12-09
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (4.631 Å)
Cite:Molecular Mechanism of V(D)J Recombination from Synaptic RAG1-RAG2 Complex Structures.
Cell(Cambridge,Mass.), 163, 2015
3T0C
  • Download 3t0c
  • View 3t0c
Molmil generated image of 3t0c
CRYSTAL STRUCTURE OF STREPTOCOCCUS MUTANS METE COMPLEXED WITH ZINC
Descriptor:5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, SULFATE ION, ZINC ION
Authors:Fu, T.M., Liang, Y.H., Su, X.D.
Deposit date:2011-07-19
Release date:2011-08-03
Last modified:2011-09-28
Method:X-RAY DIFFRACTION (2.187 Å)
Cite:Crystal Structures of Cobalamin-Independent Methionine Synthase (MetE) from Streptococcus mutans: A Dynamic Zinc-Inversion Model
J.Mol.Biol., 412, 2011
3SR7
  • Download 3sr7
  • View 3sr7
Molmil generated image of 3sr7
CRYSTAL STRUCTURE OF S. MUTANS ISOPENTENYL PYROPHOSPHATE ISOMERASE
Descriptor:Isopentenyl-diphosphate delta-isomerase, PHOSPHATE ION
Authors:Liu, Y.H., Fu, T.M., Liu, X., Su, X.D.
Deposit date:2011-07-07
Release date:2012-07-11
Method:X-RAY DIFFRACTION (2.036 Å)
Cite:Crystal structure of S. mutans isopentenyl pyrophosphate isomerase
To be Published
3SQZ
  • Download 3sqz
  • View 3sqz
Molmil generated image of 3sqz
CRYSTAL STRUCTURE OF HMG_COA SYNTHASE COMPLEXED WITH COA
Descriptor:Putative hydroxymethylglutaryl-CoA synthase, GLYCEROL, COENZYME A
Authors:Liu, Y.H., Fu, T.M., Liu, X., Su, X.D.
Deposit date:2011-07-06
Release date:2012-07-11
Last modified:2014-02-05
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Crystal structure of HMG-CoA synthase from Streptococcus mutans
To be Published
3RNY
  • Download 3rny
  • View 3rny
Molmil generated image of 3rny
CRYSTAL STRUCTURE OF HUMAN RSK1 C-TERMINAL KINASE DOMAIN
Descriptor:Ribosomal protein S6 kinase alpha-1, SODIUM ION
Authors:Li, D., Fu, T.-M., Nan, J., Su, X.-D.
Deposit date:2011-04-24
Release date:2012-04-25
Last modified:2012-08-29
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis for the autoinhibition of the C-terminal kinase domain of human RSK1.
Acta Crystallogr.,Sect.D, 68, 2012
3LFG
  • Download 3lfg
  • View 3lfg
Molmil generated image of 3lfg
CRYSTAL STRUCTURE OF HPR-C-HIS FROM THERMOANAEROBACTER TENGCONGENSIS
Descriptor:Phosphotransferase system, HPr-related proteins
Authors:Fu, T.M., Su, X.D.
Deposit date:2010-01-17
Release date:2010-12-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Dimerization of HPr by reversible domain swapping
To be Published
3LFH
  • Download 3lfh
  • View 3lfh
Molmil generated image of 3lfh
CRYSTAL STRUCTURE OF MANXA FROM THERMOANAEROBACTER TENGCONGENSIS
Descriptor:Phosphotransferase system, mannose/fructose-specific component IIA
Authors:Fu, T.M., Su, X.-D.
Deposit date:2010-01-17
Release date:2010-12-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.805 Å)
Cite:Crystal structure of manxA and manxB from Thermoanaerobacter tengcongensis
To be Published
3LFJ
  • Download 3lfj
  • View 3lfj
Molmil generated image of 3lfj
CRYSTAL STRUCTURE OF MANXB FROM THERMOANAEROBACTER TENGCONGENSIS
Descriptor:Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB
Authors:Fu, T.M., Su, X.-D.
Deposit date:2010-01-17
Release date:2010-12-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.556 Å)
Cite:Crystal structure of manxA and manxB from Thermoanaerobacter tengcongensis
To be Published
3LE1
  • Download 3le1
  • View 3le1
Molmil generated image of 3le1
CRYSTAL STRUCTURE OF APOHPR MONOMER FROM THERMOANAEROBACTER TENGCONGENSIS
Descriptor:Phosphotransferase system, HPr-related proteins, CADMIUM ION
Authors:Fu, T.M., Su, X.D.
Deposit date:2010-01-14
Release date:2010-12-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.513 Å)
Cite:Dimerization of HPr by reversible domain swapping.
To be Published
3LE3
  • Download 3le3
  • View 3le3
Molmil generated image of 3le3
CRYSTAL STRUCTURE OF APOHPR MONOMER FROM THERMOANAEROBACTER TENGCONGENSIS
Descriptor:Phosphotransferase system, HPr-related proteins
Authors:Fu, T.M., Su, X.D.
Deposit date:2010-01-14
Release date:2010-12-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.861 Å)
Cite:Dimerization of HPr by reversible domain swapping
To be Published
3LE5
  • Download 3le5
  • View 3le5
Molmil generated image of 3le5
CRYSTAL STRUCTURE OF HPR DIMER FROM THERMOANAEROBACTER TENGCONGENSIS
Descriptor:Phosphotransferase system, HPr-related proteins
Authors:Fu, T.M., Su, X.D.
Deposit date:2010-01-14
Release date:2010-12-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Dimerization of HPr by reversible domain swapping
To be Published
<12>