Author results

1QF0
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THERMOLYSIN (E.C.3.4.24.27) COMPLEXED WITH (2-SULPHANYL-3-PHENYLPROPANOYL)-PHE-TYR. PARAMETERS FOR ZN-BIDENTATION OF MERCAPTOACYLDIPEPTIDES IN METALLOENDOPEPTIDASE
分子名称:PROTEIN (THERMOLYSIN), ZINC ION, CALCIUM ION, ...
著者Gaucher, J.-F., Selkti, M., Tiraboschi, G., Prange, T., Roques, B.P., Tomas, A., Fournie-Zaluski, M.C.
登録日1999-04-06
公開日1999-12-29
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structures of alpha-mercaptoacyldipeptides in the thermolysin active site: structural parameters for a Zn monodentation or bidentation in metalloendopeptidases.
Biochemistry, 38, 1999
1QF1
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THERMOLYSIN (E.C.3.4.24.27) COMPLEXED WITH (2-SULPHANYLHEPTANOYL)-PHE-ALA. PARAMETERS FOR ZN-BIDENTATION OF MERCAPTOACYLDIPEPTIDES IN METALLOENDOPEPTIDASE
分子名称:PROTEIN (THERMOLYSIN), ZINC ION, CALCIUM ION, ...
著者Gaucher, J.-F., Selkti, M., Tiraboschi, G., Prange, T., Roques, B.P., Tomas, A., Fournie-Zaluski, M.C.
登録日1999-04-06
公開日1999-12-29
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structures of alpha-mercaptoacyldipeptides in the thermolysin active site: structural parameters for a Zn monodentation or bidentation in metalloendopeptidases.
Biochemistry, 38, 1999
1QF2
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THERMOLYSIN (E.C.3.4.24.27) COMPLEXED WITH (2-SULPHANYL-3-PHENYLPROPANOYL)-GLY-(5-PHENYLPROLINE). PARAMETERS FOR ZN-MONODENTATION OF MERCAPTOACYLDIPEPTIDES IN METALLOENDOPEPTIDASE
分子名称:PROTEIN (THERMOLYSIN), ZINC ION, CALCIUM ION, ...
著者Gaucher, J.-F., Selkti, M., Tiraboschi, G., Prange, T., Roques, B.P., Tomas, A., Fournie-Zaluski, M.C.
登録日1999-04-06
公開日1999-12-29
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (2.06 Å)
主引用文献Crystal structures of alpha-mercaptoacyldipeptides in the thermolysin active site: structural parameters for a Zn monodentation or bidentation in metalloendopeptidases.
Biochemistry, 38, 1999
1BJ6
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1H NMR OF (12-53) NCP7/D(ACGCC) COMPLEX, 10 STRUCTURES
分子名称:DNA (5'-D(*AP*CP*GP*CP*C)-3'), NUCLEOCAPSID PROTEIN 7, ZINC ION
著者Demene, H., Morellet, N., Teilleux, V., Huynh-Dinh, T., De Rocquigny, H., Fournie-Zaluski, M.C., Roques, B.P.
登録日1998-07-03
公開日1999-02-02
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Structure of the complex between the HIV-1 nucleocapsid protein NCp7 and the single-stranded pentanucleotide d(ACGCC).
J.Mol.Biol., 283, 1998
1R1H
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STRUCTURAL ANALYSIS OF NEPRILYSIN WITH VARIOUS SPECIFIC AND POTENT INHIBITORS
分子名称:Neprilysin, N-ACETYL-D-GLUCOSAMINE, ZINC ION, ...
著者Oefner, C., Roques, B.P., Fournie-Zaluski, M.C., Dale, G.E.
登録日2003-09-24
公開日2004-09-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural analysis of neprilysin with various specific and potent inhibitors.
Acta Crystallogr.,Sect.D, 60, 2004
1R1I
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STRUCTURAL ANALYSIS OF NEPRILYSIN WITH VARIOUS SPECIFIC AND POTENT INHIBITORS
分子名称:Neprilysin, N-ACETYL-D-GLUCOSAMINE, ZINC ION, ...
著者Oefner, C., Roques, B.P., Fournie-Zaluski, M.C., Dale, G.E.
登録日2003-09-24
公開日2004-09-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural analysis of neprilysin with various specific and potent inhibitors.
Acta Crystallogr.,Sect.D, 60, 2004
1R1J
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STRUCTURAL ANALYSIS OF NEPRILYSIN WITH VARIOUS SPECIFIC AND POTENT INHIBITORS
分子名称:Neprilysin, N-ACETYL-D-GLUCOSAMINE, ZINC ION, ...
著者Oefner, C., Roques, B.P., Fournie-Zaluski, M.C., Dale, G.E.
登録日2003-09-24
公開日2004-09-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structural analysis of neprilysin with various specific and potent inhibitors.
Acta Crystallogr.,Sect.D, 60, 2004
1Z9G
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CRYSTAL STRUCTURE ANALYSIS OF THERMOLYSIN COMPLEXED WITH THE INHIBITOR (R)-RETRO-THIORPHAN
分子名称:Thermolysin, CALCIUM ION, ZINC ION, ...
著者Roderick, S.L., Fournie-Zaluski, M.C., Roques, B.P., Matthews, B.W.
登録日2005-04-01
公開日2005-04-19
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Thiorphan and retro-thiorphan display equivalent interactions when bound to crystalline thermolysin
Biochemistry, 28, 1989
1ZDP
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CRYSTAL STRUCTURE ANALYSIS OF THERMOLYSIN COMPLEXED WITH THE INHIBITOR (S)-THIORPHAN
分子名称:Thermolysin, CALCIUM ION, ZINC ION, ...
著者Roderick, S.L., Fournie-Zaluski, M.C., Roques, B.P., Matthews, B.W.
登録日2005-04-14
公開日2005-04-26
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Thiorphan and retro-thiorphan display equivalent interactions when bound to crystalline thermolysin
Biochemistry, 28, 1989
2R59
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LEUKOTRIENE A4 HYDROLASE COMPLEXED WITH INHIBITOR RB3041
分子名称:Leukotriene A-4 hydrolase, ZINC ION, YTTERBIUM (III) ION, ...
著者Tholander, F., Haeggstrom, J.Z., Thunnissen, M., Muroya, A., Roques, B.P., Fournie-Zaluski, M.C.
登録日2007-09-03
公開日2008-08-12
最終更新日2018-03-07
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Structure-based dissection of the active site chemistry of leukotriene a4 hydrolase: implications for m1 aminopeptidases and inhibitor design.
Chem.Biol., 15, 2008
2ZXG
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AMINOPEPTIDASE N COMPLEXED WITH THE AMINOPHOSPHINIC INHIBITOR OF PL250, A TRANSITION STATE ANALOGUE
分子名称:Aminopeptidase N, ZINC ION, N-{(2S)-3-[(1R)-1-aminoethyl](hydroxy)phosphoryl-2-benzylpropanoyl}-L-phenylalanine, ...
著者Nakajima, Y., Ito, K., Yoshimoto, T.
登録日2008-12-24
公開日2009-08-25
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structure of aminopeptidase N from Escherichia coli complexed with the transition-state analogue aminophosphinic inhibitor PL250
Acta Crystallogr.,Sect.D, 65, 2009
1ESK
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SOLUTION STRUCTURE OF NCP7 FROM HIV-1
分子名称:GAG POLYPROTEIN, ZINC ION
著者Morellet, N., Demene, H., Teilleux, V., Huynh-Dinh, T., de Rocquigny, H., Fournie-Zaluski, M.-C., Roques, B.P.
登録日2000-04-10
公開日2000-04-26
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Solution Structure of (12-53)NCp7 of HIV-1
To be Published
3B7R
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LEUKOTRIENE A4 HYDROLASE COMPLEXED WITH INHIBITOR RB3040
分子名称:Leukotriene A-4 hydrolase, ZINC ION, YTTERBIUM (III) ION, ...
著者Tholander, F., Haeggstrom, J., Thunnissen, M., Muroya, A., Roques, B.-P., Fournie-Zaluski, M.-C.
登録日2007-10-31
公開日2008-09-16
最終更新日2018-03-07
実験手法X-RAY DIFFRACTION (1.811 Å)
主引用文献Structure-based dissection of the active site chemistry of leukotriene a4 hydrolase: implications for m1 aminopeptidases and inhibitor design.
Chem.Biol., 15, 2008
3B7S
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[E296Q]LTA4H IN COMPLEX WITH RSR SUBSTRATE
分子名称:Leukotriene A-4 hydrolase, RSR peptide, ZINC ION, ...
著者Tholander, F., Haeggstrom, J., Thunnissen, M., Muroya, A., Roques, B.-P., Fournie-Zaluski, M.-C.
登録日2007-10-31
公開日2008-09-16
最終更新日2018-03-07
実験手法X-RAY DIFFRACTION (1.465 Å)
主引用文献Structure-based dissection of the active site chemistry of leukotriene a4 hydrolase: implications for m1 aminopeptidases and inhibitor design.
Chem.Biol., 15, 2008
3B7T
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[E296Q]LTA4H IN COMPLEX WITH ARG-ALA-ARG SUBSTRATE
分子名称:Leukotriene A-4 hydrolase, RAR peptide, ZINC ION, ...
著者Tholander, F., Haeggstrom, J., Thunnissen, M., Muroya, A., Roques, B.-P., Fournie-Zaluski, M.-C.
登録日2007-10-31
公開日2008-09-16
最終更新日2018-03-07
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure-based dissection of the active site chemistry of leukotriene a4 hydrolase: implications for m1 aminopeptidases and inhibitor design.
Chem.Biol., 15, 2008
3B7U
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LEUKOTRIENE A4 HYDROLASE COMPLEXED WITH KELATORPHAN
分子名称:Leukotriene A-4 hydrolase, ZINC ION, YTTERBIUM (III) ION, ...
著者Tholander, F., Haeggstrom, J., Thunnissen, M., Muroya, A., Roques, B.-P., Fournie-Zaluski, M.-C.
登録日2007-10-31
公開日2008-09-16
最終更新日2018-03-07
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure-based dissection of the active site chemistry of leukotriene a4 hydrolase: implications for m1 aminopeptidases and inhibitor design.
Chem.Biol., 15, 2008
1OS0
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THERMOLYSIN WITH AN ALPHA-AMINO PHOSPHINIC INHIBITOR
分子名称:Thermolysin, ZINC ION, CALCIUM ION, ...
著者Selkti, M., Tomas, A., Prange, T.
登録日2003-03-18
公開日2003-03-25
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Interactions of a new alpha-aminophosphinic derivative inside the active site of TLN (thermolysin): a model for zinc-metalloendopeptidase inhibition.
Acta Crystallogr.,Sect.D, 59, 2003
1Q3Y
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NMR STRUCTURE OF THE CYS28HIS MUTANT (D FORM) OF THE NUCLEOCAPSID PROTEIN NCP7 OF HIV-1.
分子名称:GAG protein, ZINC ION
著者Ramboarina, S., Druillennec, S., Morellet, N., Bouaziz, S., Roques, B.P.
登録日2003-08-01
公開日2004-09-07
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Target specificity of human immunodeficiency virus type 1 NCp7 requires an intact conformation of its CCHC N-terminal zinc finger.
J.Virol., 78, 2004
1Q3Z
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NMR STRUCTURE OF THE CYS28HIS MUTANT (E FORM) OF THE NUCLEOCAPSID PROTEIN NCP7 OF HIV-1.
分子名称:GAG protein, ZINC ION
著者Ramboarina, S., Druillennec, S., Morellet, N., Bouaziz, S., Roques, B.P.
登録日2003-08-01
公開日2004-09-07
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Target specificity of human immunodeficiency virus type 1 NCp7 requires an intact conformation of its CCHC N-terminal zinc finger.
J.Virol., 78, 2004