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6PAH
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BU of 6pah by Molmil
HUMAN PHENYLALANINE HYDROXYLASE CATALYTIC DOMAIN DIMER WITH BOUND L-DOPA (3,4-DIHYDROXYPHENYLALANINE) INHIBITOR
Descriptor: 3,4-DIHYDROXYPHENYLALANINE, FE (III) ION, PHENYLALANINE 4-MONOOXYGENASE
Authors:Erlandsen, H, Flatmark, T, Stevens, R.C.
Deposit date:1998-08-20
Release date:1999-04-27
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystallographic analysis of the human phenylalanine hydroxylase catalytic domain with bound catechol inhibitors at 2.0 A resolution.
Biochemistry, 37, 1998
4PAH
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BU of 4pah by Molmil
HUMAN PHENYLALANINE HYDROXYLASE CATALYTIC DOMAIN DIMER WITH BOUND NOR-ADRENALINE INHIBITOR
Descriptor: FE (III) ION, L-NOREPINEPHRINE, PHENYLALANINE HYDROXYLASE
Authors:Erlandsen, H, Flatmark, T, Stevens, R.C.
Deposit date:1998-08-20
Release date:1999-04-27
Last modified:2013-02-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystallographic analysis of the human phenylalanine hydroxylase catalytic domain with bound catechol inhibitors at 2.0 A resolution.
Biochemistry, 37, 1998
3PAH
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BU of 3pah by Molmil
HUMAN PHENYLALANINE HYDROXYLASE CATALYTIC DOMAIN DIMER WITH BOUND ADRENALINE INHIBITOR
Descriptor: 4-[(1S)-1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol, FE (III) ION, PHENYLALANINE HYDROXYLASE
Authors:Erlandsen, H, Flatmark, T, Stevens, R.C.
Deposit date:1998-08-20
Release date:1999-04-27
Last modified:2013-03-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystallographic analysis of the human phenylalanine hydroxylase catalytic domain with bound catechol inhibitors at 2.0 A resolution.
Biochemistry, 37, 1998
1DMW
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BU of 1dmw by Molmil
CRYSTAL STRUCTURE OF DOUBLE TRUNCATED HUMAN PHENYLALANINE HYDROXYLASE WITH BOUND 7,8-DIHYDRO-L-BIOPTERIN
Descriptor: 7,8-DIHYDROBIOPTERIN, FE (III) ION, PHENYLALANINE HYDROXYLASE
Authors:Erlandsen, H, Stevens, R.C, Flatmark, T.
Deposit date:1999-12-15
Release date:2000-03-24
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure and site-specific mutagenesis of pterin-bound human phenylalanine hydroxylase.
Biochemistry, 39, 2000
5PAH
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BU of 5pah by Molmil
HUMAN PHENYLALANINE HYDROXYLASE CATALYTIC DOMAIN DIMER WITH BOUND DOPAMINE INHIBITOR
Descriptor: FE (III) ION, L-DOPAMINE, PHENYLALANINE 4-MONOOXYGENASE
Authors:Erlandsen, H, Flatmark, T, Stevens, R.C.
Deposit date:1998-08-20
Release date:1999-04-27
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystallographic analysis of the human phenylalanine hydroxylase catalytic domain with bound catechol inhibitors at 2.0 A resolution.
Biochemistry, 37, 1998
1J8T
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BU of 1j8t by Molmil
Catalytic Domain of Human Phenylalanine Hydroxylase Fe(II)
Descriptor: FE (II) ION, PHENYLALANINE-4-HYDROXYLASE
Authors:Andersen, O.A, Flatmark, T, Hough, E.
Deposit date:2001-05-22
Release date:2002-05-22
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:High resolution crystal structures of the catalytic domain of human phenylalanine hydroxylase in its catalytically active Fe(II) form and binary complex with tetrahydrobiopterin.
J.Mol.Biol., 314, 2001
1J8U
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BU of 1j8u by Molmil
Catalytic Domain of Human Phenylalanine Hydroxylase Fe(II) in Complex with Tetrahydrobiopterin
Descriptor: 5,6,7,8-TETRAHYDROBIOPTERIN, FE (II) ION, PHENYLALANINE-4-HYDROXYLASE
Authors:Andersen, O.A, Flatmark, T, Hough, E.
Deposit date:2001-05-22
Release date:2002-05-22
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:High resolution crystal structures of the catalytic domain of human phenylalanine hydroxylase in its catalytically active Fe(II) form and binary complex with tetrahydrobiopterin.
J.Mol.Biol., 314, 2001
1KW0
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BU of 1kw0 by Molmil
Catalytic Domain of Human Phenylalanine Hydroxylase (Fe(II)) in Complex with Tetrahydrobiopterin and Thienylalanine
Descriptor: 5,6,7,8-TETRAHYDROBIOPTERIN, BETA(2-THIENYL)ALANINE, FE (II) ION, ...
Authors:Andersen, O.A, Flatmark, T, Hough, E.
Deposit date:2002-01-28
Release date:2003-01-28
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure of the Ternary Complex of the Catalytic Domain of Human Phenylalanine Hydroxylase with Tetrahydrobiopterin and 3-(2-thienyl)-L-alanine, and its Implications for the Mechanism of Catalysis and Substrate Activation
J.Mol.Biol., 320, 2002
1MMK
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BU of 1mmk by Molmil
Crystal structure of ternary complex of the catalytic domain of human phenylalanine hydroxylase ((FeII)) complexed with tetrahydrobiopterin and thienylalanine
Descriptor: 5,6,7,8-TETRAHYDROBIOPTERIN, BETA(2-THIENYL)ALANINE, FE (II) ION, ...
Authors:Andersen, O.A, Flatmark, T, Hough, E.
Deposit date:2002-09-04
Release date:2003-09-04
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:2.0A resolution crystal structures of the ternary complexes of human phenylalanine hydroxylase catalytic domain with tetrahydrobiopterin and 3-(2-thienyl)-L-alanine or L-norleucine: substrate specificity and molecular motions related to substrate binding
J.Mol.Biol., 333, 2003
1MMT
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BU of 1mmt by Molmil
Crystal structure of ternary complex of the catalytic domain of human phenylalanine hydroxylase (Fe(II)) complexed with tetrahydrobiopterin and norleucine
Descriptor: 5,6,7,8-TETRAHYDROBIOPTERIN, FE (II) ION, NORLEUCINE, ...
Authors:Andersen, O.A, Flatmark, T, Hough, E.
Deposit date:2002-09-04
Release date:2003-09-04
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2 Å)
Cite:2.0A resolution crystal structures of the ternary complexes of human phenylalanine hydroxylase catalytic domain with tetrahydrobiopterin and 3-(2-thienyl)-L-alanine or L-norleucine: substrate specificity and molecular motions related to substrate binding
J.Mol.Biol., 333, 2003
1PAH
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BU of 1pah by Molmil
HUMAN PHENYLALANINE HYDROXYLASE DIMER, RESIDUES 117-424
Descriptor: FE (III) ION, PHENYLALANINE HYDROXYLASE
Authors:Stevens, R.C, Erlandsen, H.
Deposit date:1997-10-25
Release date:1999-01-13
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of the catalytic domain of human phenylalanine hydroxylase reveals the structural basis for phenylketonuria.
Nat.Struct.Biol., 4, 1997
2PAH
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BU of 2pah by Molmil
TETRAMERIC HUMAN PHENYLALANINE HYDROXYLASE
Descriptor: FE (III) ION, PROTEIN (PHENYLALANINE HYDROXYLASE)
Authors:Stevens, R.C, Fusetti, F, Erlandsen, H.
Deposit date:1998-05-26
Release date:1999-10-06
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure of tetrameric human phenylalanine hydroxylase and its implications for phenylketonuria.
J.Biol.Chem., 273, 1998

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