Author results

1OEB
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MONA/GADS SH3C DOMAIN
Descriptor:GRB2-RELATED ADAPTOR PROTEIN 2, LYMPHOCYTE CYTOSOLIC PROTEIN 2, CADMIUM ION
Authors:Harkiolaki, M., Lewitzky, M., Gilbert, R.J.C., Jones, E.Y., Bourette, R.P., Mouchiroud, G., Sondermann, H., Moarefi, I., Feller, S.M.
Deposit date:2003-03-24
Release date:2003-04-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Structural Basis for SH3 Domain-Mediated High-Affinity Binding between Mona/Gads and Slp-76
Embo J., 22, 2003
1UTI
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MONA/GADS SH3C IN COMPLEX WITH HPK DERIVED PEPTIDE
Descriptor:GRB2-RELATED ADAPTOR PROTEIN 2, MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE KINASE 1
Authors:Lewitzky, M., Harkiolaki, M., Domart, M.C., Feller, S.M.
Deposit date:2003-12-09
Release date:2004-05-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Mona/Gads Sh3C Binding to Hematopoietic Progenitor Kinase 1 (Hpk1) Combines an Atypical SH3 Binding Motif, R/Kxxk, with a Classical Pxxp Motif Embedded in a Polyproline Type II (Ppii) Helix
J.Biol.Chem., 279, 2004
2BZX
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ATOMIC MODEL OF CRKL-SH3C MONOMER
Descriptor:CRK-LIKE PROTEIN
Authors:Harkiolaki, M., Gilbert, R.J., Jones, E.Y., Feller, S.M.
Deposit date:2005-08-24
Release date:2006-09-28
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The C-Terminal SH3 Domain of Crkl as a Dynamic Dimerization Module Transiently Exposing a Nuclear Export Signal.
Structure, 14, 2006
2BZY
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HOMODIMER OF CRKL-SH3C DOMAIN
Descriptor:CRK-LIKE PROTEIN
Authors:Harkiolaki, M., Gilbert, R.J., Jones, E.Y., Feller, S.M.
Deposit date:2005-08-24
Release date:2006-09-28
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The C-Terminal SH3 Domain of Crkl as a Dynamic Dimerization Module Transiently Exposing a Nuclear Export Signal.
Structure, 14, 2006
2VVK
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GRB2 SH3C (1)
Descriptor:GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2, GLYCEROL
Authors:Harkiolaki, M., Tsirka, T., Feller, S.M.
Deposit date:2008-06-09
Release date:2009-05-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Distinct Binding Modes of Two Epitopes in Gab2 that Interact with the Sh3C Domain of Grb2.
Structure, 17, 2009
2VWF
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GRB2 SH3C (2)
Descriptor:GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2, GRB2-ASSOCIATED-BINDING PROTEIN 2
Authors:Harkiolaki, M., Tsirka, T., Feller, S.M.
Deposit date:2008-06-24
Release date:2009-05-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Distinct Binding Modes of Two Epitopes in Gab2 that Interact with the Sh3C Domain of Grb2.
Structure, 17, 2009
2W0Z
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GRB2 SH3C (3)
Descriptor:GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2, GRB2-ASSOCIATED-BINDING PROTEIN 2
Authors:Harkiolaki, M., Tsirka, T., Feller, S.M.
Deposit date:2008-10-13
Release date:2009-05-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Distinct Binding Modes of Two Epitopes in Gab2 that Interact with the Sh3C Domain of Grb2.
Structure, 17, 2009
2W10
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MONA SH3C IN COMPLEX
Descriptor:GRB2-RELATED ADAPTOR PROTEIN 2, TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 23, PHOSPHATE ION
Authors:Harkiolaki, M., Feller, S.M.
Deposit date:2008-10-13
Release date:2009-05-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Distinct Binding Modes of Two Epitopes in Gab2 that Interact with the Sh3C Domain of Grb2.
Structure, 17, 2009
3RNJ
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CRYSTAL STRUCTURE OF THE SH3 DOMAIN FROM IRSP53 (BAIAP2)
Descriptor:Brain-specific angiogenesis inhibitor 1-associated protein 2, {[-(BIS-CARBOXYMETHYL-AMINO)-ETHYL]-CARBOXYMETHYL-AMINO}-ACETIC ACID, 1,2-ETHANEDIOL, ...
Authors:Simister, P.C., Barilari, M., Muniz, J.R.C., Dente, L., Knapp, S., von Delft, F., Filippakopoulos, P., Vollmar, M., Chaikuad, A., Raynor, J., Tregubova, A., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Bountra, C., Feller, S.M., Structural Genomics Consortium (SGC)
Deposit date:2011-04-22
Release date:2011-05-04
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structure of the SH3 domain from IRSp53 (BAIAP2)
To be Published
3U23
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ATOMIC RESOLUTION CRYSTAL STRUCTURE OF THE 2ND SH3 DOMAIN FROM HUMAN CD2AP (CMS) IN COMPLEX WITH A PROLINE-RICH PEPTIDE FROM HUMAN RIN3
Descriptor:CD2-associated protein, Ras and Rab interactor 3, 1,2-ETHANEDIOL
Authors:Simister, P.C., Rouka, E., Janning, M., Muniz, J.R.C., Kirsch, K.H., Knapp, S., von Delft, F., Filippakopoulos, P., Arrowsmith, C.H., Krojer, T., Edwards, A.M., Weigelt, J., Bountra, C., Feller, S.M., Structural Genomics Consortium (SGC)
Deposit date:2011-09-30
Release date:2011-12-28
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.11 Å)
Cite:Differential Recognition Preferences of the Three Src Homology 3 (SH3) Domains from the Adaptor CD2-associated Protein (CD2AP) and Direct Association with Ras and Rab Interactor 3 (RIN3).
J.Biol.Chem., 290, 2015
4WCI
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CRYSTAL STRUCTURE OF THE 1ST SH3 DOMAIN FROM HUMAN CD2AP (CMS) IN COMPLEX WITH A PROLINE-RICH PEPTIDE (AA 378-393) FROM HUMAN RIN3
Descriptor:CD2-associated protein, Ras and Rab interactor 3, SULFATE ION
Authors:Rouka, E., Simister, P.C., Janning, M., Kirsch, K.H., Krojer, T., Knapp, S., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Feller, S.M., Structural Genomics Consortium (SGC)
Deposit date:2014-09-04
Release date:2015-08-19
Last modified:2016-02-24
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Differential Recognition Preferences of the Three Src Homology 3 (SH3) Domains from the Adaptor CD2-associated Protein (CD2AP) and Direct Association with Ras and Rab Interactor 3 (RIN3).
J.Biol.Chem., 290, 2015
4X1V
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CRYSTAL STRUCTURE OF THE 2ND SH3 DOMAIN FROM HUMAN CD2AP (CMS) IN COMPLEX WITH A PROLINE-RICH PEPTIDE (AA 76-91) FROM HUMAN ARAP1
Descriptor:CD2-associated protein, Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1
Authors:Rouka, E., Krojer, T., von Delft, F., Knapp, S., Kirsch, K.H., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Feller, S.M., Simister, P.C.
Deposit date:2014-11-25
Release date:2016-02-17
Last modified:2016-02-24
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Crystal structure of the 2nd SH3 domain from human CD2AP (CMS) in complex with a proline-rich peptide (aa 76-91) from human ARAP1
to be published
1CKA
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STRUCTURAL BASIS FOR THE SPECIFIC INTERACTION OF LYSINE-CONTAINING PROLINE-RICH PEPTIDES WITH THE N-TERMINAL SH3 DOMAIN OF C-CRK
Descriptor:C-CRK N-TERMINAL SH3 DOMAIN, C3G PEPTIDE (PRO-PRO-PRO-ALA-LEU-PRO-PRO-LYS-LYS-ARG)
Authors:Wu, X., Kuriyan, J.
Deposit date:1995-01-24
Release date:1995-05-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural basis for the specific interaction of lysine-containing proline-rich peptides with the N-terminal SH3 domain of c-Crk.
Structure, 3, 1995
1CKB
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STRUCTURAL BASIS FOR THE SPECIFIC INTERACTION OF LYSINE-CONTAINING PROLINE-RICH PEPTIDES WITH THE N-TERMINAL SH3 DOMAIN OF C-CRK
Descriptor:C-CRK N-TERMINAL SH3 DOMAIN, SOS PEPTIDE (PRO-PRO-PRO-VAL-PRO-PRO-ARG-ARG-ARG-ARG)
Authors:Wu, X., Kuriyan, J.
Deposit date:1995-01-24
Release date:1995-05-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for the specific interaction of lysine-containing proline-rich peptides with the N-terminal SH3 domain of c-Crk.
Structure, 3, 1995
1H92
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SH3 DOMAIN OF HUMAN LCK TYROSINE KINASE
Descriptor:PROTO-ONCOGENE TYROSINE-PROTEIN KINASE LCK
Authors:Schweimer, K., Hoffmann, S., Friedrich, U., Biesinger, B., Roesch, P., Sticht, H.
Deposit date:2001-02-22
Release date:2001-10-22
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural Investigation of the Binding of a Herpesviral Protein to the SH3 Domain of Tyrosine Kinase Lck
Biochemistry, 41, 2002
1WA7
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SH3 DOMAIN OF HUMAN LYN TYROSINE KINASE IN COMPLEX WITH A HERPESVIRAL LIGAND
Descriptor:TYROSINE-PROTEIN KINASE LYN, HYPOTHETICAL 28.7 KDA PROTEIN IN DHFR 3'REGION (ORF1)
Authors:Bauer, F., Schweimer, K., Hoffmann, S., Roesch, P., Sticht, H.
Deposit date:2004-10-25
Release date:2005-07-07
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural Investigation of the Binding of a Herpesviral Protein to the SH3 Domain of Tyrosine Kinase Lck.
Biochemistry, 41, 2002