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2L28
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SOLUTION STRUCTURE OF LACTOBACILLUS CASEI DIHYDROFOLATE REDUCTASE APO-FORM, 25 CONFORMERS
Descriptor:Dihydrofolate reductase
Authors:Polshakov, V.I., Birdsall, B., Feeney, J.
Deposit date:2010-08-13
Release date:2011-04-06
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:NMR Structures of Apo L. casei Dihydrofolate Reductase and Its Complexes with Trimethoprim and NADPH: Contributions to Positive Cooperative Binding from Ligand-Induced Refolding, Conformational Changes, and Interligand Hydrophobic Interactions.
Biochemistry, 50, 2011
2LF1
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SOLUTION STRUCTURE OF L. CASEI DIHYDROFOLATE REDUCTASE COMPLEXED WITH NADPH, 30 STRUCTURES
Descriptor:Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Polshakov, V., Feeney, J., Birdsall, B., Kovalevskaya, N.
Deposit date:2011-06-28
Release date:2011-12-21
Method:SOLUTION NMR
Cite:NMR structures of apo L. casei dihydrofolate reductase and its complexes with trimethoprim and NADPH: contributions to positive cooperative binding from ligand-induced refolding, conformational changes, and interligand hydrophobic interactions
Biochemistry, 50, 2011
1LUD
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SOLUTION STRUCTURE OF DIHYDROFOLATE REDUCTASE COMPLEXED WITH TRIMETHOPRIM AND NADPH, 24 STRUCTURES
Descriptor:DIHYDROFOLATE REDUCTASE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 2,4-DIAMINO-5-(3,4,5-TRIMETHOXY-BENZYL)-PYRIMIDIN-1-IUM
Authors:Polshakov, V.I., Smirnov, E.G., Birdsall, B., Kelly, G., Feeney, J.
Deposit date:2002-05-22
Release date:2002-12-18
Last modified:2016-12-28
Method:SOLUTION NMR
Cite:NMR-based solution structure of the complex of Lactobacillus casei dihydrofolate reductase with trimethoprim and NADPH
J.Biomol.Nmr, 24, 2002
1DIS
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DIHYDROFOLATE REDUCTASE (E.C.1.5.1.3) COMPLEX WITH BRODIMOPRIM-4,6-DICARBOXYLATE
Descriptor:DIHYDROFOLATE REDUCTASE, BRODIMOPRIM-4,6-DICARBOXYLATE
Authors:Morgan, W.D., Birdsall, B., Polshakov, V.I., Sali, D., Kompis, I., Feeney, J.
Deposit date:1995-08-01
Release date:1995-11-14
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of a brodimoprim analogue in its complex with Lactobacillus casei dihydrofolate reductase.
Biochemistry, 34, 1995
1DIU
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DIHYDROFOLATE REDUCTASE (E.C.1.5.1.3) COMPLEX WITH BRODIMOPRIM-4,6-DICARBOXYLATE
Descriptor:DIHYDROFOLATE REDUCTASE, BRODIMOPRIM-4,6-DICARBOXYLATE
Authors:Morgan, W.D., Birdsall, B., Polshakov, V.I., Sali, D., Kompis, I., Feeney, J.
Deposit date:1995-08-01
Release date:1995-11-14
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of a brodimoprim analogue in its complex with Lactobacillus casei dihydrofolate reductase.
Biochemistry, 34, 1995
1HI7
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NMR SOLUTION STRUCTURE OF THE DISULPHIDE-LINKED HOMODIMER OF HUMAN TFF1, 10 STRUCTURES
Descriptor:PS2 PROTEIN
Authors:Williams, M.A., Feeney, J.
Deposit date:2001-01-03
Release date:2001-01-03
Last modified:2019-04-10
Method:SOLUTION NMR
Cite:The Solution Structure of the Disulphide-Linked Dimeric of the Human Trefoil Protein Tff1
FEBS Lett., 493, 2001
2TMP
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N-TERMINAL DOMAIN OF TISSUE INHIBITOR OF METALLOPROTEINASE-2 (N-TIMP-2), NMR, 49 STRUCTURES
Descriptor:TISSUE INHIBITOR OF METALLOPROTEINASES-2
Authors:Muskett, F.W., Frenkiel, T.A., Feeney, J., Freedman, R.B., Carr, M.D., Williamson, R.A.
Deposit date:1998-05-26
Release date:1998-12-09
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:High resolution structure of the N-terminal domain of tissue inhibitor of metalloproteinases-2 and characterization of its interaction site with matrix metalloproteinase-3.
J.Biol.Chem., 273, 1998
1A5J
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CHICKEN B-MYB DNA BINDING DOMAIN, REPEAT 2 AND REPEAT3, NMR, 32 STRUCTURES
Descriptor:B-MYB
Authors:Mcintosh, P.B., Carr, M.D., Wollborn, U., Frenkiel, T.A., Feeney, J., Mccormick, J.E., Klempnauer, K.H.
Deposit date:1998-02-16
Release date:1998-07-01
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the B-Myb DNA-binding domain: a possible role for conformational instability of the protein in DNA binding and control of gene expression.
Biochemistry, 37, 1998
1BZF
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NMR SOLUTION STRUCTURE AND DYNAMICS OF THE COMPLEX OF LACTOBACILLUS CASEI DIHYDROFOLATE REDUCTASE WITH THE NEW LIPOPHILIC ANTIFOLATE DRUG TRIMETREXATE, 22 STRUCTURES
Descriptor:DIHYDROFOLATE REDUCTASE, TRIMETREXATE
Authors:Polshakov, V.I., Birdsall, B., Frenkiel, T.A., Gargaro, A.R., Feeney, J.
Deposit date:1998-10-28
Release date:1999-05-18
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure and dynamics in solution of the complex of Lactobacillus casei dihydrofolate reductase with the new lipophilic antifolate drug trimetrexate.
Protein Sci., 8, 1999
1PS2
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HIGH RESOLUTION NMR SOLUTION STRUCTURE OF HUMAN PS2, 19 STRUCTURES
Descriptor:PS2
Authors:Williams, M.A., Polshakov, V.I., Gargaro, A.R., Feeney, J.
Deposit date:1997-01-07
Release date:1997-07-07
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:High-resolution solution structure of human pNR-2/pS2: a single trefoil motif protein.
J.Mol.Biol., 267, 1997
1AO8
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DIHYDROFOLATE REDUCTASE COMPLEXED WITH METHOTREXATE, NMR, 21 STRUCTURES
Descriptor:DIHYDROFOLATE REDUCTASE, METHOTREXATE
Authors:Gargaro, A.R., Soteriou, A., Frenkiel, T.A., Bauer, C.J., Birdsall, B., Polshakov, V.I., Barsukov, I.L., Roberts, G.C.K., Feeney, J.
Deposit date:1997-07-22
Release date:1998-02-25
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The solution structure of the complex of Lactobacillus casei dihydrofolate reductase with methotrexate.
J.Mol.Biol., 277, 1998
1CEJ
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SOLUTION STRUCTURE OF AN EGF MODULE PAIR FROM THE PLASMODIUM FALCIPARUM MEROZOITE SURFACE PROTEIN 1
Descriptor:PROTEIN (MEROZOITE SURFACE PROTEIN 1)
Authors:Morgan, W.D., Birdsall, B., Frenkiel, T.A., Gradwell, M.G., Burghaus, P.A., Syed, S.E.H., Uthaipibull, C., Holder, A.A., Feeney, J.
Deposit date:1999-03-08
Release date:1999-05-28
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of an EGF module pair from the Plasmodium falciparum merozoite surface protein 1.
J.Mol.Biol., 289, 1999
1PCP
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SOLUTION STRUCTURE OF A TREFOIL-MOTIF-CONTAINING CELL GROWTH FACTOR, PORCINE SPASMOLYTIC PROTEIN
Descriptor:PORCINE SPASMOLYTIC PROTEIN
Authors:Carr, M.D., Bauer, C.J., Gradwell, M.J., Feeney, J.
Deposit date:1993-02-04
Release date:1994-05-31
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Solution structure of a trefoil-motif-containing cell growth factor, porcine spasmolytic protein.
Proc.Natl.Acad.Sci.USA, 91, 1994
1PE3
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SOLUTION STRUCTURE OF THE DISULPHIDE-LINKED DIMER OF HUMAN INTESTINAL TREFOIL FACTOR (TFF3)
Descriptor:Trefoil factor 3
Authors:Muskett, F.W., May, F.E., Westley, B.R., Feeney, J.
Deposit date:2003-05-21
Release date:2004-03-09
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the disulfide-linked dimer of human intestinal trefoil factor (TFF3): the intermolecular orientation and interactions are markedly different from those of other dimeric trefoil proteins.
Biochemistry, 42, 2003
2NPR
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STRUCTURAL STUDIES ON PLASMODIUM VIVAX MEROZOITE SURFACE PROTEIN-1
Descriptor:Merozoite surface protein 1
Authors:Babon, J.J., Morgan, W.D., Kelly, G., Eccleston, J.F., Feeney, J., Holder, A.A.
Deposit date:2006-10-29
Release date:2007-03-20
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural studies on Plasmodium vivax merozoite surface protein-1
Mol.Biochem.Parasitol., 153, 2007
2HM9
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SOLUTION STRUCTURE OF DIHYDROFOLATE REDUCTASE COMPLEXED WITH TRIMETHOPRIM, 33 STRUCTURES
Descriptor:Dihydrofolate reductase, 2,4-DIAMINO-5-(3,4,5-TRIMETHOXY-BENZYL)-PYRIMIDIN-1-IUM
Authors:Polshakov, V.I., Birdsall, B.
Deposit date:2006-07-11
Release date:2007-06-05
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:NMR structures of apo L.casei dihydrofolate reductase and its complexes with trimethoprim and NADPH. Contributions to positive cooperative binding from ligand-induced refolding, conformational changes and interligand hydrophobic interactions
Biochemistry, 2011
1YHO
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SOLUTION STRUCTURE OF HUMAN DIHYDROFOLATE REDUCTASE COMPLEXED WITH TRIMETHOPRIM AND NADPH, 25 STRUCTURES
Descriptor:Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 2,4-DIAMINO-5-(3,4,5-TRIMETHOXY-BENZYL)-PYRIMIDIN-1-IUM
Authors:Polshakov, V.I., Birdsall, B.
Deposit date:2005-01-10
Release date:2005-11-22
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of human dihydrofolate reductase in its complex with trimethoprim and NADPH.
J.Biomol.Nmr, 33, 2005
2HQP
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SOLUTION STRUCTURE OF L.CASEI DIHYDROFOLATE REDUCTASE COMPLEXED WITH NADPH, 32 STRUCTURES
Descriptor:Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Polshakov, V.I., Birdsall, B.
Deposit date:2006-07-19
Release date:2007-06-05
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural insights into cooperative effects of ligand binding to L. casei dihydrofolate redutase
TO BE PUBLISHED