Author results

1VAF
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INDUCIBLE NITRIC OXIDE SYNTHASE OXYGENASE DOMAIN COMPLEXED WITH THE INHIBITOR AR-R17477
Descriptor:Nitric oxide synthase, inducible, ZINC ION, ...
Authors:Fedorov, R., Vasan, R., Ghosh, D.K., Schlichting, I.
Deposit date:2004-02-16
Release date:2004-06-01
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structures of nitric oxide synthase isoforms complexed with the inhibitor AR-R17477 suggest a rational basis for specificity and inhibitor design
Proc.Natl.Acad.Sci.USA, 101, 2004
1VAG
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NEURONAL NITRIC OXIDE SYNTHASE OXYGENASE DOMAIN COMPLEXED WITH THE INHIBITOR AR-R17477
Descriptor:Nitric-oxide synthase, brain, ZINC ION, ...
Authors:Fedorov, R., Vasan, R., Ghosh, D.K., Schlichting, I.
Deposit date:2004-02-16
Release date:2004-06-01
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of nitric oxide synthase isoforms complexed with the inhibitor AR-R17477 suggest a rational basis for specificity and inhibitor design
Proc.Natl.Acad.Sci.USA, 101, 2004
2JHR
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CRYSTAL STRUCTURE OF MYOSIN-2 MOTOR DOMAIN IN COMPLEX WITH ADP- METAVANADATE AND PENTABROMOPSEUDILIN
Descriptor:MYOSIN-2 HEAVY CHAIN, ADP METAVANADATE, MAGNESIUM ION, ...
Authors:Fedorov, R., Boehl, M., Tsiavaliaris, G., Hartmann, F.K., Baruch, P., Brenner, B., Martin, R., Knoelker, H.J., Gutzeit, H.O., Manstein, D.J.
Deposit date:2008-03-25
Release date:2009-01-13
Last modified:2018-02-28
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The Mechanism of Pentabromopseudilin Inhibition of Myosin Motor Activity.
Nat.Struct.Mol.Biol., 16, 2009
2JJ9
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CRYSTAL STRUCTURE OF MYOSIN-2 IN COMPLEX WITH ADP-METAVANADATE
Descriptor:MYOSIN-2 HEAVY CHAIN, ADP METAVANADATE, MAGNESIUM ION
Authors:Fedorov, R., Boehl, M., Tsiavaliaris, G., Hartmann, F.K., Baruch, P., Brenner, B., Martin, R., Knoelker, H.J., Gutzeit, H.O., Manstein, D.J.
Deposit date:2008-03-25
Release date:2009-01-13
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The Mechanism of Pentabromopseudilin Inhibition of Myosin Motor Activity.
Nat.Struct.Mol.Biol., 16, 2009
3MJX
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CRYSTAL STRUCTURE OF MYOSIN-2 MOTOR DOMAIN IN COMPLEX WITH ADP-METAVANADATE AND BLEBBISTATIN
Descriptor:Myosin-2 heavy chain, ADP METAVANADATE, MAGNESIUM ION, ...
Authors:Fedorov, R., Baruch, P., Bauer, S., Manstein, D.J.
Deposit date:2010-04-13
Release date:2011-04-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The mechanism of pentabromopseudilin inhibition of myosin motor activity.
Nat.Struct.Mol.Biol., 16, 2009
1BXY
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CRYSTAL STRUCTURE OF RIBOSOMAL PROTEIN L30 FROM THERMUS THERMOPHILUS AT 1.9 A RESOLUTION: CONFORMATIONAL FLEXIBILITY OF THE MOLECULE.
Descriptor:PROTEIN (RIBOSOMAL PROTEIN L30)
Authors:Fedorov, R., Nevskaya, N., Khairullina, A., Tishchenko, S., Mikhailov, A., Garber, M., Nikonov, S.
Deposit date:1998-10-09
Release date:1998-10-14
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of ribosomal protein L30 from Thermus thermophilus at 1.9 A resolution: conformational flexibility of the molecule.
Acta Crystallogr.,Sect.D, 55, 1999
1N2N
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CRYSTAL STRUCTURE OF CYANIDE COMPLEX OF THE OXYGENASE DOMAIN OF INDUCIBLE NITRIC OXIDE SYNTHASE.
Descriptor:Inducible Nitric Oxide Synthase, CYANIDE ION, ZINC ION, ...
Authors:Fedorov, R., Ghosh, D.K., Schlichting, I.
Deposit date:2002-10-23
Release date:2003-02-11
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structures of cyanide complexes of P450cam and the oxygenase domain of inducible nitric oxide synthase-structural models of the short-lived oxygen complexes
Arch.Biochem.Biophys., 409, 2003
1N9L
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CRYSTAL STRUCTURE OF THE PHOT-LOV1 DOMAIN FROM CHLAMYDOMONAS REINHARDTII IN THE DARK STATE.
Descriptor:putative blue light receptor, SULFATE ION, FLAVIN MONONUCLEOTIDE
Authors:Fedorov, R., Schlichting, I., Hartmann, E., Domratcheva, T., Fuhrmann, M., Hegemann, P.
Deposit date:2002-11-25
Release date:2003-06-17
Last modified:2019-11-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structures and molecular mechanism of a light-induced signaling switch: The Phot-LOV1 domain from Chlamydomonas reinhardtii.
Biophys.J., 84, 2003
1N9N
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CRYSTAL STRUCTURE OF THE PHOT-LOV1 DOMAIN FROM CHLAMYDOMONAS REINHARDTII IN ILLUMINATED STATE. DATA SET OF A SINGLE CRYSTAL.
Descriptor:putative blue light receptor, FLAVIN MONONUCLEOTIDE
Authors:Fedorov, R., Schlichting, I., Hartmann, E., Domratcheva, T., Fuhrmann, M., Hegemann, P.
Deposit date:2002-11-25
Release date:2003-06-17
Last modified:2019-11-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures and molecular mechanism of a light-induced signaling switch: The Phot-LOV1 domain from Chlamydomonas reinhardtii.
Biophys.J., 84, 2003
1N9O
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CRYSTAL STRUCTURE OF THE PHOT-LOV1 DOMAIN FROM CHLAMYDOMONAS REINHARDTII IN ILLUMINATED STATE. COMPOSITE DATA SET.
Descriptor:putative blue light receptor, SULFATE ION, FLAVIN MONONUCLEOTIDE
Authors:Fedorov, R., Schlichting, I., Hartmann, E., Domratcheva, T., Fuhrmann, M., Hegemann, P.
Deposit date:2002-11-25
Release date:2003-06-17
Last modified:2019-11-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structures and molecular mechanism of a light-induced signaling switch: The Phot-LOV1 domain from Chlamydomonas reinhardtii.
Biophys.J., 84, 2003
1O76
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CYANIDE COMPLEX OF P450CAM FROM PSEUDOMONAS PUTIDA
Descriptor:CYTOCHROME P450-CAM, PROTOPORPHYRIN IX CONTAINING FE, CYANIDE ION, ...
Authors:Fedorov, R., Ghosh, D., Schlichting, I.
Deposit date:2002-10-23
Release date:2002-12-19
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structures of Cyanide Complexes of P450Cam and the Oxygenase Domain of Inducible Nitric Oxide Synthase-Structural Models of the Short-Lived Oxygen Complexes
Arch.Biochem.Biophys., 409, 2003
1QW4
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CRYSTAL STRUCTURE OF MURINE INDUCIBLE NITRIC OXIDE SYNTHASE OXYGENASE DOMAIN IN COMPLEX WITH N-OMEGA-PROPYL-L-ARGININE.
Descriptor:Nitric oxide synthase, inducible, ZINC ION, ...
Authors:Fedorov, R., Hartmann, E., Ghosh, D.K., Schlichting, I.
Deposit date:2003-08-31
Release date:2003-12-09
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis for the specificity of the nitric-oxide synthase inhibitors W1400 and Nomega-propyl-L-Arg for the inducible and neuronal isoforms.
J.Biol.Chem., 278, 2003
1QW5
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MURINE INDUCIBLE NITRIC OXIDE SYNTHASE OXYGENASE DOMAIN IN COMPLEX WITH W1400 INHIBITOR.
Descriptor:Nitric oxide synthase, inducible, ZINC ION, ...
Authors:Fedorov, R., Hartmann, E., Ghosh, D.K., Schlichting, I.
Deposit date:2003-08-31
Release date:2003-12-09
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis for the specificity of the nitric-oxide synthase inhibitors W1400 and Nomega-propyl-L-Arg for the inducible and neuronal isoforms.
J.Biol.Chem., 278, 2003
1QW6
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RAT NEURONAL NITRIC OXIDE SYNTHASE OXYGENASE DOMAIN IN COMPLEX WITH N-OMEGA-PROPYL-L-ARG.
Descriptor:Nitric-oxide synthase, brain, ZINC ION, ...
Authors:Fedorov, R., Hartmann, E., Ghosh, D.K., Schlichting, I.
Deposit date:2003-09-01
Release date:2003-12-09
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis for the specificity of the nitric-oxide synthase inhibitors W1400 and Nomega-propyl-L-Arg for the inducible and neuronal isoforms.
J.Biol.Chem., 278, 2003
1QWC
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RAT NEURONAL NITRIC OXIDE SYNTHASE OXYGENASE DOMAIN IN COMPLEX WITH W1400 INHIBITOR.
Descriptor:Nitric-oxide synthase, brain, ZINC ION, ...
Authors:Fedorov, R., Hartmann, E., Ghosh, D.K., Schlichting, I.
Deposit date:2003-09-02
Release date:2003-12-09
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for the specificity of the nitric-oxide synthase inhibitors W1400 and Nomega-propyl-L-Arg for the inducible and neuronal isoforms.
J.Biol.Chem., 278, 2003
2IHE
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CRYSTAL STRUCTURE OF WILD-TYPE SINGLE-STRANDED DNA BINDING PROTEIN FROM THERMUS AQUATICUS
Descriptor:Single-stranded DNA-binding protein
Authors:Fedorov, R., Witte, G., Urbanke, C., Manstein, D.J., Curth, U.
Deposit date:2006-09-26
Release date:2007-01-02
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:3D structure of Thermus aquaticus single-stranded DNA-binding protein gives insight into the functioning of SSB proteins.
Nucleic Acids Res., 34, 2006
2IHF
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CRYSTAL STRUCTURE OF DELETION MUTANT DELTA 228-252 R190A OF THE SINGLE-STRANDED DNA BINDING PROTEIN FROM THERMUS AQUATICUS
Descriptor:Single-stranded DNA-binding protein
Authors:Fedorov, R., Witte, G., Urbanke, C., Manstein, D.J., Curth, U.
Deposit date:2006-09-26
Release date:2007-01-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:3D structure of Thermus aquaticus single-stranded DNA-binding protein gives insight into the functioning of SSB proteins.
Nucleic Acids Res., 34, 2006
4RWN
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CRYSTAL STRUCTURE OF THE PRE-REACTIVE STATE OF PORCINE OAS1
Descriptor:2'-5'-oligoadenylate synthase 1, RNA (5'-R(*GP*GP*CP*UP*UP*UP*UP*GP*AP*CP*CP*UP*UP*UP*AP*UP*GP*AP*A)-3'), RNA (5'-R(*UP*UP*CP*AP*UP*AP*AP*AP*GP*GP*UP*CP*AP*AP*AP*AP*GP*CP*C)-3'), ...
Authors:Lohoefener, J., Steinke, N., Kay-Fedorov, P., Baruch, P., Nikulin, A., Tishchenko, S., Manstein, D.J., Fedorov, R.
Deposit date:2014-12-05
Release date:2015-05-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Activation Mechanism of 2'-5'-Oligoadenylate Synthetase Gives New Insights Into OAS/cGAS Triggers of Innate Immunity.
Structure, 23, 2015
4RWO
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CRYSTAL STRUCTURE OF THE PORCINE OAS1 L149R MUTANT IN COMPLEX WITH DSRNA AND APCPP IN THE AMP DONOR POSITION
Descriptor:RNA (5'-R(*GP*GP*CP*UP*UP*UP*UP*GP*AP*CP*CP*UP*UP*UP*AP*UP*GP*AP*A)-3'), RNA (5'-R(*UP*UP*CP*AP*UP*AP*AP*AP*GP*GP*UP*CP*AP*AP*AP*AP*GP*CP*C)-3'), 2'-5'-oligoadenylate synthase 1, ...
Authors:Lohoefener, J., Steinke, N., Kay-Fedorov, P., Baruch, P., Nikulin, A., Tishchenko, S., Manstein, D.J., Fedorov, R.
Deposit date:2014-12-05
Release date:2015-05-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The Activation Mechanism of 2'-5'-Oligoadenylate Synthetase Gives New Insights Into OAS/cGAS Triggers of Innate Immunity.
Structure, 23, 2015
4RWP
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CRYSTAL STRUCTURE OF PORCINE OAS1 IN COMPLEX WITH DSRNA
Descriptor:2'-5'-oligoadenylate synthase 1, RNA (5'-R(*GP*GP*CP*UP*UP*UP*UP*GP*AP*CP*CP*UP*UP*UP*AP*UP*GP*AP*A)-3'), RNA (5'-R(*UP*UP*CP*AP*UP*AP*AP*AP*GP*GP*UP*CP*AP*AP*AP*AP*GP*CP*C)-3')
Authors:Lohoefener, J., Steinke, N., Kay-Fedorov, P., Baruch, P., Nikulin, A., Tishchenko, S., Manstein, D.J., Fedorov, R.
Deposit date:2014-12-05
Release date:2015-05-20
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:The Activation Mechanism of 2'-5'-Oligoadenylate Synthetase Gives New Insights Into OAS/cGAS Triggers of Innate Immunity.
Structure, 23, 2015
4RWQ
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CRYSTAL STRUCTURE OF THE APO-STATE OF PORCINE OAS1
Descriptor:2'-5'-oligoadenylate synthase 1
Authors:Lohoefener, J., Steinke, N., Kay-Fedorov, P., Baruch, P., Nikulin, A., Tishchenko, S., Manstein, D.J., Fedorov, R.
Deposit date:2014-12-05
Release date:2015-05-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:The Activation Mechanism of 2'-5'-Oligoadenylate Synthetase Gives New Insights Into OAS/cGAS Triggers of Innate Immunity.
Structure, 23, 2015
2XEL
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MOLECULAR MECHANISM OF PENTACHLOROPSEUDILIN MEDIATED INHIBITION OF MYOSIN MOTOR ACTIVITY
Descriptor:MYOSIN-2 HEAVY CHAIN, ADP METAVANADATE, MAGNESIUM ION, ...
Authors:Chinthalapudi, K., Taft, M.H., Martin, R., Hartmann, F.K., Heissler, S.M., Tsiavaliaris, G., Gutzeit, H.O., Knoelker, H.J., Coluccio, L.M., Fedorov, R., Manstein, D.J.
Deposit date:2010-05-16
Release date:2011-06-15
Last modified:2011-08-31
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Mechanism and Specificity of Pentachloropseudilin-Mediated Inhibition of Myosin Motor Activity.
J.Biol.Chem., 286, 2011
4J18
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CRYSTAL STRUCTURE OF H191L MUTANT OF UDP-GLUCOSE PYROPHOSPHORYLASE FROM LEISHMANIA MAJOR
Descriptor:UDP-glucose pyrophosphorylase
Authors:Fuehring, J.I., Routier, F.H., Lamerz, A.-C., Baruch, P., Gerardy-Schahn, R., Fedorov, R.
Deposit date:2013-02-01
Release date:2014-01-29
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Catalytic Mechanism and Allosteric Regulation of UDP-Glucose Pyrophosphorylase from Leishmania major
ACS CATALYSIS, 3, 2013
4M28
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UDP-GLUCOSE PYROPHOSPHORYLASE FROM LEISHMANIA MAJOR IN COMPLEX WITH UTP ANALOG DUPCPP
Descriptor:UDP-glucose pyrophosphorylase, 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]uridine
Authors:Fuehring, J.I., Routier, F.H., Lamerz, A.-C., Baruch, P., Gerardy-Schahn, R., Fedorov, R.
Deposit date:2013-08-05
Release date:2014-01-29
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (3 Å)
Cite:Catalytic mechanism and allosteric regulation of UDP-glucose pyrophosphorylase from Leishmania major
ACS CATALYSIS, 3, 2013
4M2A
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CRYSTAL STRUCTURE OF THE UDP-GLUCOSE PYROPHOSPHORYLASE FROM LEISHMANIA MAJOR IN THE POST-REACTIVE STATE
Descriptor:UDP-glucose pyrophosphorylase, URIDINE-5'-DIPHOSPHATE-GLUCOSE, MAGNESIUM ION, ...
Authors:Fuehring, J., Routier, F.H., Lamerz, A.-C., Baruch, P., Gerardy-Schahn, R., Fedorov, R.
Deposit date:2013-08-05
Release date:2014-01-29
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Catalytic Mechanism and Allosteric Regulation of Udp-Glucose Pyrophosphorylase from Leishmania Major
ACS CATALYSIS, 3, 2013
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